Effective Use of Angiotensin II in Coronavirus Disease 19–Associated Mixed Shock State: A Case Report
Identifieur interne : 001299 ( Ncbi/Checkpoint ); précédent : 001298; suivant : 001300Effective Use of Angiotensin II in Coronavirus Disease 19–Associated Mixed Shock State: A Case Report
Auteurs : Kevin A. Bobeck ; Arthur W. Holtzclaw ; Tara E. Brown ; Paul A. ClarkSource :
- A&a Practice [ 2575-3126 ] ; 2020.
Abstract
The rapid spread of Coronavirus Disease 2019 (COVID-19) has sparked a search for effective therapies. The discovery that the virus binds the angiotensin-converting enzyme 2 (ACE2) receptor has led to investigation of the renin–angiotensin system for possible therapeutic targets. We present a case of an elderly woman with multiple comorbidities who developed severe acute respiratory distress syndrome (ARDS), a cardiomyopathy, and vasodilatory shock secondary to COVID-19 and was treated with exogenous angiotensin II. She rapidly demonstrated significant hemodynamic improvement without noted adverse effects. Thus, we propose further investigation into possible benefits of angiotensin II in shock secondary to COVID-19.
Url:
DOI: 10.1213/XAA.0000000000001221
PubMed: NONE
PubMed Central: 7172437
Affiliations:
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PMC:7172437Le document en format XML
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