Effective Use of Angiotensin II in Coronavirus Disease 19–Associated Mixed Shock State: A Case Report
Identifieur interne : 001299 ( Ncbi/Curation ); précédent : 001298; suivant : 001300Effective Use of Angiotensin II in Coronavirus Disease 19–Associated Mixed Shock State: A Case Report
Auteurs : Kevin A. Bobeck ; Arthur W. Holtzclaw ; Tara E. Brown ; Paul A. ClarkSource :
- A&a Practice [ 2575-3126 ] ; 2020.
Abstract
The rapid spread of Coronavirus Disease 2019 (COVID-19) has sparked a search for effective therapies. The discovery that the virus binds the angiotensin-converting enzyme 2 (ACE2) receptor has led to investigation of the renin–angiotensin system for possible therapeutic targets. We present a case of an elderly woman with multiple comorbidities who developed severe acute respiratory distress syndrome (ARDS), a cardiomyopathy, and vasodilatory shock secondary to COVID-19 and was treated with exogenous angiotensin II. She rapidly demonstrated significant hemodynamic improvement without noted adverse effects. Thus, we propose further investigation into possible benefits of angiotensin II in shock secondary to COVID-19.
Url:
DOI: 10.1213/XAA.0000000000001221
PubMed: NONE
PubMed Central: 7172437
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Arthur W. Holtzclaw<affiliation><nlm:aff id="aff2">Pulmonary, Walter Reed National Military Medical Center, Bethesda, Maryland.</nlm:aff><wicri:noCountry code="subfield">Maryland.</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Pulmonary, Walter Reed National Military Medical Center, Bethesda, Maryland.</nlm:aff><wicri:noCountry code="subfield">Maryland.</wicri:noCountry></affiliation>Le document en format XML
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Bobeck</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Holtzclaw, Arthur W" sort="Holtzclaw, Arthur W" uniqKey="Holtzclaw A" first="Arthur W." last="Holtzclaw">Arthur W. Holtzclaw</name><affiliation><nlm:aff id="aff2">Pulmonary, Walter Reed National Military Medical Center, Bethesda, Maryland.</nlm:aff><wicri:noCountry code="subfield">Maryland.</wicri:noCountry></affiliation></author><author><name sortKey="Brown, Tara E" sort="Brown, Tara E" uniqKey="Brown T" first="Tara E." last="Brown">Tara E. Brown</name><affiliation><nlm:aff id="aff2">Pulmonary, Walter Reed National Military Medical Center, Bethesda, Maryland.</nlm:aff><wicri:noCountry code="subfield">Maryland.</wicri:noCountry></affiliation></author><author><name sortKey="Clark, Paul A" sort="Clark, Paul A" uniqKey="Clark P" first="Paul A." last="Clark">Paul A. Clark</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author></analytic><series><title level="j">A&a Practice</title><idno type="eISSN">2575-3126</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The rapid spread of Coronavirus Disease 2019 (COVID-19) has sparked a search for effective therapies. The discovery that the virus binds the angiotensin-converting enzyme 2 (ACE2) receptor has led to investigation of the renin–angiotensin system for possible therapeutic targets. We present a case of an elderly woman with multiple comorbidities who developed severe acute respiratory distress syndrome (ARDS), a cardiomyopathy, and vasodilatory shock secondary to COVID-19 and was treated with exogenous angiotensin II. She rapidly demonstrated significant hemodynamic improvement without noted adverse effects. Thus, we propose further investigation into possible benefits of angiotensin II in shock secondary to COVID-19.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Letko, M" uniqKey="Letko M">M Letko</name></author><author><name sortKey="Marzi, A" uniqKey="Marzi A">A Marzi</name></author><author><name sortKey="Munster, V" uniqKey="Munster V">V Munster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tikellis, C" uniqKey="Tikellis C">C Tikellis</name></author><author><name sortKey="Thomas, Mc" uniqKey="Thomas M">MC Thomas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xu, H" uniqKey="Xu H">H Xu</name></author><author><name sortKey="Zhong, L" uniqKey="Zhong L">L Zhong</name></author><author><name sortKey="Deng, J" uniqKey="Deng J">J Deng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Turner, Aj" uniqKey="Turner A">AJ Turner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chow, Jh" uniqKey="Chow J">JH Chow</name></author><author><name sortKey="Mazzeffi, Ma" uniqKey="Mazzeffi M">MA Mazzeffi</name></author><author><name sortKey="Mccurdy, Mt" uniqKey="Mccurdy M">MT McCurdy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tran, K" uniqKey="Tran K">K Tran</name></author><author><name sortKey="Cimon, K" uniqKey="Cimon K">K Cimon</name></author><author><name sortKey="Severn, M" uniqKey="Severn M">M Severn</name></author><author><name sortKey="Pessoa Silva, Cl" uniqKey="Pessoa Silva C">CL Pessoa-Silva</name></author><author><name sortKey="Conly, J" uniqKey="Conly J">J Conly</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gautret, P" uniqKey="Gautret P">P Gautret</name></author><author><name sortKey="Lagier, J C" uniqKey="Lagier J">J-C Lagier</name></author><author><name sortKey="Parola, P" uniqKey="Parola P">P Parola</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Onder, G" uniqKey="Onder G">G Onder</name></author><author><name sortKey="Rezza, G" uniqKey="Rezza G">G Rezza</name></author><author><name sortKey="Brusaferro, S" uniqKey="Brusaferro S">S Brusaferro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khanna, A" uniqKey="Khanna A">A Khanna</name></author><author><name sortKey="Ostermann, M" uniqKey="Ostermann M">M Ostermann</name></author><author><name sortKey="Bellomo, R" uniqKey="Bellomo R">R Bellomo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tumlin, Ja" uniqKey="Tumlin J">JA Tumlin</name></author><author><name sortKey="Murugan, R" uniqKey="Murugan R">R Murugan</name></author><author><name sortKey="Deane, Am" uniqKey="Deane A">AM Deane</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y Liu</name></author><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y Yang</name></author><author><name sortKey="Zhang, C" uniqKey="Zhang C">C Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chawla, Ls" uniqKey="Chawla L">LS Chawla</name></author><author><name sortKey="Chen, S" uniqKey="Chen S">S Chen</name></author><author><name sortKey="Bellomo, R" uniqKey="Bellomo R">R Bellomo</name></author><author><name sortKey="Tidmarsh, Gf" uniqKey="Tidmarsh G">GF Tidmarsh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lyon, Ar" uniqKey="Lyon A">AR Lyon</name></author><author><name sortKey="Bossone, E" uniqKey="Bossone E">E Bossone</name></author><author><name sortKey="Schneider, B" uniqKey="Schneider B">B Schneider</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Celi, A" uniqKey="Celi A">A Celi</name></author><author><name sortKey="Cianchetti, S" uniqKey="Cianchetti S">S Cianchetti</name></author><author><name sortKey="Dell Mo, G" uniqKey="Dell Mo G">G Dell’Omo</name></author><author><name sortKey="Pedrinelli, R" uniqKey="Pedrinelli R">R Pedrinelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hanify, Jm" uniqKey="Hanify J">JM Hanify</name></author><author><name sortKey="Dupree, Lh" uniqKey="Dupree L">LH Dupree</name></author><author><name sortKey="Johnson, Dw" uniqKey="Johnson D">DW Johnson</name></author><author><name sortKey="Ferreira, Ja" uniqKey="Ferreira J">JA Ferreira</name></author></analytic></biblStruct></listBibl></div1></back></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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