Immune regulation of the unfolded protein response at the mucosal barrier in viral infection
Identifieur interne : 000A02 ( Main/Exploration ); précédent : 000A01; suivant : 000A03Immune regulation of the unfolded protein response at the mucosal barrier in viral infection
Auteurs : Ran Wang ; Md. Moniruzzaman ; Eric Shuffle ; Rohan Lourie ; Sumaira Z. HasnainSource :
- Clinical & Translational Immunology [ 2050-0068 ] ; 2018.
Abstract
Protein folding in the endoplasmic reticulum (
Url:
DOI: 10.1002/cti2.1014
PubMed: 29632667
PubMed Central: 5881172
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000891
- to stream Pmc, to step Curation: 000891
- to stream Pmc, to step Checkpoint: 000743
- to stream Ncbi, to step Merge: 000924
- to stream Ncbi, to step Curation: 000924
- to stream Ncbi, to step Checkpoint: 000924
- to stream Main, to step Merge: 000A03
- to stream Main, to step Curation: 000A02
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Immune regulation of the unfolded protein response at the mucosal barrier in viral infection</title>
<author><name sortKey="Wang, Ran" sort="Wang, Ran" uniqKey="Wang R" first="Ran" last="Wang">Ran Wang</name>
<affiliation><nlm:aff id="cti21014-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="cti21014-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Moniruzzaman, Md" sort="Moniruzzaman, Md" uniqKey="Moniruzzaman M" first="Md." last="Moniruzzaman">Md. Moniruzzaman</name>
<affiliation><nlm:aff id="cti21014-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="cti21014-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Shuffle, Eric" sort="Shuffle, Eric" uniqKey="Shuffle E" first="Eric" last="Shuffle">Eric Shuffle</name>
<affiliation><nlm:aff id="cti21014-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lourie, Rohan" sort="Lourie, Rohan" uniqKey="Lourie R" first="Rohan" last="Lourie">Rohan Lourie</name>
<affiliation><nlm:aff id="cti21014-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="cti21014-aff-0003"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hasnain, Sumaira Z" sort="Hasnain, Sumaira Z" uniqKey="Hasnain S" first="Sumaira Z" last="Hasnain">Sumaira Z. Hasnain</name>
<affiliation><nlm:aff id="cti21014-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="cti21014-aff-0002"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">29632667</idno>
<idno type="pmc">5881172</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881172</idno>
<idno type="RBID">PMC:5881172</idno>
<idno type="doi">10.1002/cti2.1014</idno>
<date when="2018">2018</date>
<idno type="wicri:Area/Pmc/Corpus">000891</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000891</idno>
<idno type="wicri:Area/Pmc/Curation">000891</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000891</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000743</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000743</idno>
<idno type="wicri:Area/Ncbi/Merge">000924</idno>
<idno type="wicri:Area/Ncbi/Curation">000924</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000924</idno>
<idno type="wicri:Area/Main/Merge">000A03</idno>
<idno type="wicri:Area/Main/Curation">000A02</idno>
<idno type="wicri:Area/Main/Exploration">000A02</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Immune regulation of the unfolded protein response at the mucosal barrier in viral infection</title>
<author><name sortKey="Wang, Ran" sort="Wang, Ran" uniqKey="Wang R" first="Ran" last="Wang">Ran Wang</name>
<affiliation><nlm:aff id="cti21014-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="cti21014-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Moniruzzaman, Md" sort="Moniruzzaman, Md" uniqKey="Moniruzzaman M" first="Md." last="Moniruzzaman">Md. Moniruzzaman</name>
<affiliation><nlm:aff id="cti21014-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="cti21014-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Shuffle, Eric" sort="Shuffle, Eric" uniqKey="Shuffle E" first="Eric" last="Shuffle">Eric Shuffle</name>
<affiliation><nlm:aff id="cti21014-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lourie, Rohan" sort="Lourie, Rohan" uniqKey="Lourie R" first="Rohan" last="Lourie">Rohan Lourie</name>
<affiliation><nlm:aff id="cti21014-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="cti21014-aff-0003"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hasnain, Sumaira Z" sort="Hasnain, Sumaira Z" uniqKey="Hasnain S" first="Sumaira Z" last="Hasnain">Sumaira Z. Hasnain</name>
<affiliation><nlm:aff id="cti21014-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="cti21014-aff-0002"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Clinical & Translational Immunology</title>
<idno type="eISSN">2050-0068</idno>
<imprint><date when="2018">2018</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>Abstract</title>
<p>Protein folding in the endoplasmic reticulum (<styled-content style="fixed-case" toggle="no">ER</styled-content>
) is subject to stringent quality control. When protein secretion demand exceeds the protein folding capacity of the <styled-content style="fixed-case" toggle="no">ER</styled-content>
, the unfolded protein response (<styled-content style="fixed-case" toggle="no">UPR</styled-content>
) is triggered as a consequence of <styled-content style="fixed-case" toggle="no">ER</styled-content>
stress. Due to the secretory function of epithelial cells, <styled-content style="fixed-case" toggle="no">UPR</styled-content>
plays an important role in maintaining epithelial barrier function at mucosal sites. <styled-content style="fixed-case" toggle="no">ER</styled-content>
stress and activation of the <styled-content style="fixed-case" toggle="no">UPR</styled-content>
are natural mechanisms by which mucosal epithelial cells combat viral infections. In this review, we discuss the important role of <styled-content style="fixed-case" toggle="no">UPR</styled-content>
in regulating mucosal epithelium homeostasis. In addition, we review current insights into how the <styled-content style="fixed-case" toggle="no">UPR</styled-content>
is involved in viral infection at mucosal barriers and potential therapeutic strategies that restore epithelial cell integrity following acute viral infections via cytokine and cellular stress manipulation.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Hasnain, Sumaira Z" sort="Hasnain, Sumaira Z" uniqKey="Hasnain S" first="Sumaira Z" last="Hasnain">Sumaira Z. Hasnain</name>
<name sortKey="Lourie, Rohan" sort="Lourie, Rohan" uniqKey="Lourie R" first="Rohan" last="Lourie">Rohan Lourie</name>
<name sortKey="Moniruzzaman, Md" sort="Moniruzzaman, Md" uniqKey="Moniruzzaman M" first="Md." last="Moniruzzaman">Md. Moniruzzaman</name>
<name sortKey="Shuffle, Eric" sort="Shuffle, Eric" uniqKey="Shuffle E" first="Eric" last="Shuffle">Eric Shuffle</name>
<name sortKey="Wang, Ran" sort="Wang, Ran" uniqKey="Wang R" first="Ran" last="Wang">Ran Wang</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/StressCovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A02 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000A02 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= StressCovidV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:5881172 |texte= Immune regulation of the unfolded protein response at the mucosal barrier in viral infection }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:29632667" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a StressCovidV1
This area was generated with Dilib version V0.6.33. |