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Management of inpatients exposed to an outbreak of severe acute respiratory syndrome (SARS).

Identifieur interne : 002A90 ( PubMed/Curation ); précédent : 002A89; suivant : 002A91

Management of inpatients exposed to an outbreak of severe acute respiratory syndrome (SARS).

Auteurs : Y-M Tan [Singapour] ; P K H. Chow ; B-H Tan ; A. Kurup ; B K T. Tan ; F L S. Tan ; J. Seldrup ; D M K. Heng ; B. Ang ; J. Green ; C-Y Wong ; K-C Soo

Source :

RBID : pubmed:15501336

Descripteurs français

English descriptors

Abstract

This is a prospective observational study of a cohort of inpatients exposed to a severe acute respiratory syndrome (SARS) outbreak. Strict infection control policies were instituted. The 70 patients exposed to the SARS outbreak were isolated from the rest of the hospital. They were triaged, quarantined and cohorted in three open plan wards. Selective isolation was carried out immediately when symptoms and signs suspicious of SARS manifested clinically. The patients' ages ranged from 21 to 90 years and 56% had surgery before the quarantine. Sixteen patients with unexplained fever during the period of quarantine were isolated, seven of whom were eventually diagnosed with probable SARS. The crude incidence of SARS in our cohort was 10%. The SARS case fatality was 14%. No secondary transmission of the SARS virus within the cohort was observed. Strict infection control, together with appropriate triaging, cohorting and selective isolation, is an effective and practical model of intervention in cohorts exposed to a SARS outbreak. Such a management strategy eases the logistic constraints imposed by demands for large numbers of isolation facilities in the face of a massive outbreak.

DOI: 10.1016/j.jhin.2004.06.013
PubMed: 15501336

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pubmed:15501336

Le document en format XML

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<div type="abstract" xml:lang="en">This is a prospective observational study of a cohort of inpatients exposed to a severe acute respiratory syndrome (SARS) outbreak. Strict infection control policies were instituted. The 70 patients exposed to the SARS outbreak were isolated from the rest of the hospital. They were triaged, quarantined and cohorted in three open plan wards. Selective isolation was carried out immediately when symptoms and signs suspicious of SARS manifested clinically. The patients' ages ranged from 21 to 90 years and 56% had surgery before the quarantine. Sixteen patients with unexplained fever during the period of quarantine were isolated, seven of whom were eventually diagnosed with probable SARS. The crude incidence of SARS in our cohort was 10%. The SARS case fatality was 14%. No secondary transmission of the SARS virus within the cohort was observed. Strict infection control, together with appropriate triaging, cohorting and selective isolation, is an effective and practical model of intervention in cohorts exposed to a SARS outbreak. Such a management strategy eases the logistic constraints imposed by demands for large numbers of isolation facilities in the face of a massive outbreak.</div>
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<Citation>MMWR Morb Mortal Wkly Rep. 2003 Apr 4;52(13):269-72</Citation>
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<Citation>Wkly Epidemiol Rec. 2003 Apr 11;78(15):121-2</Citation>
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