SrasV1, PubMed, Curation, bibRecord, 002682

Genetic lesions within the 3a gene of SARS-CoV.

Identifieur interne : 002682 ( PubMed/Curation ); précédent : 002681; suivant : 002683

Genetic lesions within the 3a gene of SARS-CoV.

Auteurs : Timothy H P. Tan [Singapour] ; Timothy Barkham ; Burtram C. Fielding ; Chih-Fong Chou ; Shuo Shen ; Seng Gee Lim ; Wanjin Hong ; Yee-Joo Tan

Source :

Virology journal [ 1743-422X ] ; 2005.

RBID : pubmed:15963240

Descripteurs français

KwdFr :
- ARN viral (génétique), Humains, Mutation avec décalage du cadre de lecture, Protéines virales (génétique), Syndrome respiratoire aigu sévère (virologie), Virus du SRAS (génétique), Virus du SRAS (isolement et purification).
MESH :
- génétique : ARN viral, Protéines virales, Virus du SRAS.
- isolement et purification : Virus du SRAS.
- virologie : Syndrome respiratoire aigu sévère.
- Humains, Mutation avec décalage du cadre de lecture.

English descriptors

KwdEn :
- Frameshift Mutation, Humans, RNA, Viral (genetics), SARS Virus (genetics), SARS Virus (isolation & purification), Severe Acute Respiratory Syndrome (virology), Viral Proteins (genetics).
MESH :
- chemical , genetics : RNA, Viral, Viral Proteins.
- genetics : SARS Virus.
- isolation & purification : SARS Virus.
- virology : Severe Acute Respiratory Syndrome.
- Frameshift Mutation, Humans.

Abstract

A series of frameshift mutations within the 3a gene has been observed in culture-derived severe acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical samples obtained from SARS-CoV infected patients also contains a heterogeneous population of wild-type and mutant 3a transcripts.

DOI: 10.1186/1743-422X-2-51
PubMed: 15963240

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pubmed:15963240

Le document en format XML

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<author><name sortKey="Tan, Timothy H P" sort="Tan, Timothy H P" uniqKey="Tan T" first="Timothy H P" last="Tan">Timothy H P. Tan</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute of Molecular and Cell Biology, 61 Biopolis Drive, 138673, Singapore. ttan@imcb.a-star.edu.sg</nlm:affiliation>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea>Institute of Molecular and Cell Biology, 61 Biopolis Drive, 138673</wicri:regionArea>
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<author><name sortKey="Barkham, Timothy" sort="Barkham, Timothy" uniqKey="Barkham T" first="Timothy" last="Barkham">Timothy Barkham</name>
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<author><name sortKey="Fielding, Burtram C" sort="Fielding, Burtram C" uniqKey="Fielding B" first="Burtram C" last="Fielding">Burtram C. Fielding</name>
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<author><name sortKey="Chou, Chih Fong" sort="Chou, Chih Fong" uniqKey="Chou C" first="Chih-Fong" last="Chou">Chih-Fong Chou</name>
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<author><name sortKey="Shen, Shuo" sort="Shen, Shuo" uniqKey="Shen S" first="Shuo" last="Shen">Shuo Shen</name>
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<author><name sortKey="Lim, Seng Gee" sort="Lim, Seng Gee" uniqKey="Lim S" first="Seng Gee" last="Lim">Seng Gee Lim</name>
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<author><name sortKey="Hong, Wanjin" sort="Hong, Wanjin" uniqKey="Hong W" first="Wanjin" last="Hong">Wanjin Hong</name>
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<author><name sortKey="Tan, Yee Joo" sort="Tan, Yee Joo" uniqKey="Tan Y" first="Yee-Joo" last="Tan">Yee-Joo Tan</name>
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Genetic lesions within the 3a gene of SARS-CoV.

Genetic lesions within the 3a gene of SARS-CoV.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki