Extremely low exposure of a community to severe acute respiratory syndrome coronavirus: false seropositivity due to use of bacterially derived antigens.
Identifieur interne : 002112 ( PubMed/Curation ); précédent : 002111; suivant : 002113Extremely low exposure of a community to severe acute respiratory syndrome coronavirus: false seropositivity due to use of bacterially derived antigens.
Auteurs : D T M. Leung [Hong Kong] ; W W C. Van Maren ; F K L. Chan ; W S Chan ; A W I. Lo ; C H Ma ; F C H. Tam ; K F To ; P K S. Chan ; J J Y. Sung ; P L LimSource :
- Journal of virology [ 0022-538X ] ; 2006.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (sang), Cellules Vero, Dépistage systématique, Faux positifs, Hong Kong, Humains, Immunoglobulines (), Immunoglobulines (sang), Protéines nucléocapside (métabolisme), Spécificité des anticorps, Syndrome respiratoire aigu sévère (diagnostic), Syndrome respiratoire aigu sévère (épidémiologie), Transfection, Virus du SRAS (pathogénicité), Épitopes (), Études de cohortes.
- MESH :
- diagnostic : Syndrome respiratoire aigu sévère.
- métabolisme : Protéines nucléocapside.
- pathogénicité : Virus du SRAS.
- sang : Anticorps antiviraux, Immunoglobulines.
- épidémiologie : Syndrome respiratoire aigu sévère.
- Animaux, Cellules Vero, Dépistage systématique, Faux positifs, Hong Kong, Humains, Immunoglobulines, Spécificité des anticorps, Transfection, Épitopes, Études de cohortes.
- Wicri :
- geographic : Hong Kong.
English descriptors
- KwdEn :
- Animals, Antibodies, Viral (blood), Antibody Specificity, Chlorocebus aethiops, Cohort Studies, Epitopes (chemistry), False Positive Reactions, Hong Kong, Humans, Immunoglobulins (blood), Immunoglobulins (chemistry), Mass Screening, Nucleocapsid Proteins (metabolism), SARS Virus (pathogenicity), Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (epidemiology), Transfection, Vero Cells.
- MESH :
- chemical , blood : Antibodies, Viral, Immunoglobulins.
- chemical , chemistry : Epitopes, Immunoglobulins.
- chemical , metabolism : Nucleocapsid Proteins.
- geographic : Hong Kong.
- diagnosis : Severe Acute Respiratory Syndrome.
- epidemiology : Severe Acute Respiratory Syndrome.
- pathogenicity : SARS Virus.
- Animals, Antibody Specificity, Chlorocebus aethiops, Cohort Studies, False Positive Reactions, Humans, Mass Screening, Transfection, Vero Cells.
Abstract
Estimates of seropositivity to a new infectious agent in a community are useful to public health. For severe acute respiratory syndrome (SARS), the figures are conflicting. Herein, we screened 12,000 people in a community stricken by SARS 10 months previously and found 53 individuals (0.44%) who had immunoglobulin G antibodies to the SARS coronavirus (SARS-CoV) nucleocapsid (N) produced in bacteria. However, only seven of these (group 1) had sera which also reacted with the native N antigen expressed in SARS-CoV-infected Vero cells, N-transfected 293T cells, and tissues of infected SARS patients. Of these, six individuals had had SARS previously. The remaining person, as well as the 46 other individuals (group 2), were healthy and had no history of SARS. Group 1 antibodies recognized epitopes located slightly differently in N from those of group 2 antibodies, and a mouse hybridoma antibody resembling the former type was generated. Unusually, group 2 antibodies appeared to recognize cross-reactive bacterial epitopes that presumably were posttranslationally modified in eukaryotes and hence were probably not induced by SARS-CoV or related coronaviruses but rather by bacteria. The N antigen is thus highly unique. The extremely low rate (0.008%) of asymptomatic SARS infection found attests to the high virulence of the SARS-CoV virus.
DOI: 10.1128/JVI.00649-06
PubMed: 16940504
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Sung</name></author><author><name sortKey="Lim, P L" sort="Lim, P L" uniqKey="Lim P" first="P L" last="Lim">P L Lim</name></author></analytic><series><title level="j">Journal of virology</title><idno type="ISSN">0022-538X</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antibodies, Viral (blood)</term><term>Antibody Specificity</term><term>Chlorocebus aethiops</term><term>Cohort Studies</term><term>Epitopes (chemistry)</term><term>False Positive Reactions</term><term>Hong Kong</term><term>Humans</term><term>Immunoglobulins (blood)</term><term>Immunoglobulins (chemistry)</term><term>Mass Screening</term><term>Nucleocapsid Proteins (metabolism)</term><term>SARS Virus (pathogenicity)</term><term>Severe Acute Respiratory Syndrome (diagnosis)</term><term>Severe Acute Respiratory Syndrome (epidemiology)</term><term>Transfection</term><term>Vero Cells</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Anticorps antiviraux (sang)</term><term>Cellules Vero</term><term>Dépistage systématique</term><term>Faux positifs</term><term>Hong Kong</term><term>Humains</term><term>Immunoglobulines ()</term><term>Immunoglobulines (sang)</term><term>Protéines nucléocapside (métabolisme)</term><term>Spécificité des anticorps</term><term>Syndrome respiratoire aigu sévère (diagnostic)</term><term>Syndrome respiratoire aigu sévère (épidémiologie)</term><term>Transfection</term><term>Virus du SRAS (pathogénicité)</term><term>Épitopes ()</term><term>Études de cohortes</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Viral</term><term>Immunoglobulins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Epitopes</term><term>Immunoglobulins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Nucleocapsid Proteins</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Hong Kong</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Protéines nucléocapside</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antiviraux</term><term>Immunoglobulines</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Antibody Specificity</term><term>Chlorocebus aethiops</term><term>Cohort Studies</term><term>False Positive Reactions</term><term>Humans</term><term>Mass Screening</term><term>Transfection</term><term>Vero Cells</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Cellules Vero</term><term>Dépistage systématique</term><term>Faux positifs</term><term>Hong Kong</term><term>Humains</term><term>Immunoglobulines</term><term>Spécificité des anticorps</term><term>Transfection</term><term>Épitopes</term><term>Études de cohortes</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Hong Kong</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Estimates of seropositivity to a new infectious agent in a community are useful to public health. For severe acute respiratory syndrome (SARS), the figures are conflicting. Herein, we screened 12,000 people in a community stricken by SARS 10 months previously and found 53 individuals (0.44%) who had immunoglobulin G antibodies to the SARS coronavirus (SARS-CoV) nucleocapsid (N) produced in bacteria. However, only seven of these (group 1) had sera which also reacted with the native N antigen expressed in SARS-CoV-infected Vero cells, N-transfected 293T cells, and tissues of infected SARS patients. Of these, six individuals had had SARS previously. The remaining person, as well as the 46 other individuals (group 2), were healthy and had no history of SARS. Group 1 antibodies recognized epitopes located slightly differently in N from those of group 2 antibodies, and a mouse hybridoma antibody resembling the former type was generated. Unusually, group 2 antibodies appeared to recognize cross-reactive bacterial epitopes that presumably were posttranslationally modified in eukaryotes and hence were probably not induced by SARS-CoV or related coronaviruses but rather by bacteria. The N antigen is thus highly unique. The extremely low rate (0.008%) of asymptomatic SARS infection found attests to the high virulence of the SARS-CoV virus.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">16940504</PMID><DateCompleted><Year>2006</Year><Month>10</Month><Day>20</Day></DateCompleted><DateRevised><Year>2019</Year><Month>12</Month><Day>10</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0022-538X</ISSN><JournalIssue CitedMedium="Print"><Volume>80</Volume><Issue>18</Issue><PubDate><Year>2006</Year><Month>Sep</Month></PubDate></JournalIssue><Title>Journal of virology</Title><ISOAbbreviation>J. Virol.</ISOAbbreviation></Journal><ArticleTitle>Extremely low exposure of a community to severe acute respiratory syndrome coronavirus: false seropositivity due to use of bacterially derived antigens.</ArticleTitle><Pagination><MedlinePgn>8920-8</MedlinePgn></Pagination><Abstract><AbstractText>Estimates of seropositivity to a new infectious agent in a community are useful to public health. For severe acute respiratory syndrome (SARS), the figures are conflicting. Herein, we screened 12,000 people in a community stricken by SARS 10 months previously and found 53 individuals (0.44%) who had immunoglobulin G antibodies to the SARS coronavirus (SARS-CoV) nucleocapsid (N) produced in bacteria. However, only seven of these (group 1) had sera which also reacted with the native N antigen expressed in SARS-CoV-infected Vero cells, N-transfected 293T cells, and tissues of infected SARS patients. Of these, six individuals had had SARS previously. The remaining person, as well as the 46 other individuals (group 2), were healthy and had no history of SARS. Group 1 antibodies recognized epitopes located slightly differently in N from those of group 2 antibodies, and a mouse hybridoma antibody resembling the former type was generated. Unusually, group 2 antibodies appeared to recognize cross-reactive bacterial epitopes that presumably were posttranslationally modified in eukaryotes and hence were probably not induced by SARS-CoV or related coronaviruses but rather by bacteria. The N antigen is thus highly unique. The extremely low rate (0.008%) of asymptomatic SARS infection found attests to the high virulence of the SARS-CoV virus.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Leung</LastName><ForeName>D T M</ForeName><Initials>DT</Initials><AffiliationInfo><Affiliation>Clinical Immunology Unit, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Maren</LastName><ForeName>W W C</ForeName><Initials>WW</Initials></Author><Author ValidYN="Y"><LastName>Chan</LastName><ForeName>F K L</ForeName><Initials>FK</Initials></Author><Author ValidYN="Y"><LastName>Chan</LastName><ForeName>W S</ForeName><Initials>WS</Initials></Author><Author ValidYN="Y"><LastName>Lo</LastName><ForeName>A W I</ForeName><Initials>AW</Initials></Author><Author ValidYN="Y"><LastName>Ma</LastName><ForeName>C H</ForeName><Initials>CH</Initials></Author><Author ValidYN="Y"><LastName>Tam</LastName><ForeName>F C H</ForeName><Initials>FC</Initials></Author><Author ValidYN="Y"><LastName>To</LastName><ForeName>K F</ForeName><Initials>KF</Initials></Author><Author ValidYN="Y"><LastName>Chan</LastName><ForeName>P K S</ForeName><Initials>PK</Initials></Author><Author ValidYN="Y"><LastName>Sung</LastName><ForeName>J J Y</ForeName><Initials>JJ</Initials></Author><Author ValidYN="Y"><LastName>Lim</LastName><ForeName>P L</ForeName><Initials>PL</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Virol</MedlineTA><NlmUniqueID>0113724</NlmUniqueID><ISSNLinking>0022-538X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000914">Antibodies, Viral</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000939">Epitopes</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007136">Immunoglobulins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D019590">Nucleocapsid Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C099602">nucleocapsid protein, Coronavirus</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000914" MajorTopicYN="N">Antibodies, Viral</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000918" MajorTopicYN="N">Antibody Specificity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002522" MajorTopicYN="N">Chlorocebus aethiops</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000939" MajorTopicYN="N">Epitopes</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005189" MajorTopicYN="N">False Positive Reactions</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006723" MajorTopicYN="N" Type="Geographic">Hong Kong</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007136" MajorTopicYN="N">Immunoglobulins</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000737" 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19;361(9366):1319-25</Citation><ArticleIdList><ArticleId IdType="pubmed">12711465</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2003 May 30;300(5624):1394-9</Citation><ArticleIdList><ArticleId IdType="pubmed">12730500</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2003 May 30;300(5624):1399-404</Citation><ArticleIdList><ArticleId IdType="pubmed">12730501</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2003 Nov;9(11):1453-4</Citation><ArticleIdList><ArticleId IdType="pubmed">14718090</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Pathol. 2004 Mar;57(3):260-5</Citation><ArticleIdList><ArticleId IdType="pubmed">14990596</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2004 Feb;10(2):176-8</Citation><ArticleIdList><ArticleId IdType="pubmed">15030679</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2004 Feb;10(2):249-50</Citation><ArticleIdList><ArticleId IdType="pubmed">15030691</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2004 Mar 13;363(9412):841-5</Citation><ArticleIdList><ArticleId IdType="pubmed">15031027</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 1999 Apr 15;162(8):5011-8</Citation><ArticleIdList><ArticleId IdType="pubmed">10202050</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15748-53</Citation><ArticleIdList><ArticleId IdType="pubmed">15496474</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Microbiol. 2004 Dec;42(12):5885-8</Citation><ArticleIdList><ArticleId IdType="pubmed">15583332</ArticleId></ArticleIdList></Reference><Reference><Citation>J Gen Virol. 2005 Jan;86(Pt 1):211-5</Citation><ArticleIdList><ArticleId IdType="pubmed">15604448</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Diagn Lab Immunol. 2005 Apr;12(4):552-4</Citation><ArticleIdList><ArticleId IdType="pubmed">15817766</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2005 Jun 15;191(12):2033-7</Citation><ArticleIdList><ArticleId IdType="pubmed">15897988</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Diagn Lab Immunol. 2005 Jul;12(7):848-54</Citation><ArticleIdList><ArticleId IdType="pubmed">16002634</ArticleId></ArticleIdList></Reference><Reference><Citation>Scand J Infect Dis. 2005;37(6-7):500-3</Citation><ArticleIdList><ArticleId IdType="pubmed">16012012</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Med. 2005 Aug;11(8):875-9</Citation><ArticleIdList><ArticleId IdType="pubmed">16007097</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2005 Sep;79(17):11476-86</Citation><ArticleIdList><ArticleId IdType="pubmed">16103198</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Immunol. 2005 Dec;5(12):917-27</Citation><ArticleIdList><ArticleId IdType="pubmed">16322745</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Genet. 2006 Jan;38(1):38-46</Citation><ArticleIdList><ArticleId IdType="pubmed">16369534</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2006 Mar 15;193(6):792-5</Citation><ArticleIdList><ArticleId IdType="pubmed">16479513</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Microbiol. 2004 May;42(5):2351-2</Citation><ArticleIdList><ArticleId IdType="pubmed">15131233</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2004 Jun;78(11):5612-8</Citation><ArticleIdList><ArticleId IdType="pubmed">15140958</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2004 May 29;363(9423):1825; author reply 1826-7</Citation><ArticleIdList><ArticleId IdType="pubmed">15172784</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Microbiol. 2004 Jun;42(6):2629-35</Citation><ArticleIdList><ArticleId IdType="pubmed">15184444</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2004 Jul 15;190(2):379-86</Citation><ArticleIdList><ArticleId IdType="pubmed">15216476</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Infect Dis. 2004 Jun 15;38(12):e116-8</Citation><ArticleIdList><ArticleId IdType="pubmed">15227633</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Microbiol. 2004 Jul;42(7):2884-9</Citation><ArticleIdList><ArticleId IdType="pubmed">15243033</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2004 Sep 15;190(6):1119-26</Citation><ArticleIdList><ArticleId IdType="pubmed">15319862</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2004 Sep;10(9):1653-6</Citation><ArticleIdList><ArticleId IdType="pubmed">15498170</ArticleId></ArticleIdList></Reference><Reference><Citation>Int Immunol. 2001 Sep;13(9):1099-107</Citation><ArticleIdList><ArticleId IdType="pubmed">11526090</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2001 Dec 27;345(26):1877-82</Citation><ArticleIdList><ArticleId IdType="pubmed">11756578</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1953-66</Citation><ArticleIdList><ArticleId IdType="pubmed">12690092</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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|type= RBID
|clé= pubmed:16940504
|texte= Extremely low exposure of a community to severe acute respiratory syndrome coronavirus: false seropositivity due to use of bacterially derived antigens.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:16940504" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |