SrasV1, PubMed, Curation, bibRecord, 001229

The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease.

Identifieur interne : 001229 ( PubMed/Curation ); précédent : 001228; suivant : 001230

The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease.

Auteurs : Zhilin Ren [République populaire de Chine] ; Liming Yan ; Ning Zhang ; Yu Guo ; Cheng Yang ; Zhiyong Lou ; Zihe Rao

Source :

Protein & cell [ 1674-8018 ] ; 2013.

RBID : pubmed:23549610

Descripteurs français

KwdFr :
- Cysteine endopeptidases (métabolisme), Humains, Inhibiteurs de protéases (), Inhibiteurs de protéases (métabolisme), Inhibiteurs de protéases (pharmacologie), Isoxazoles (), Isoxazoles (pharmacologie), Protéines virales (antagonistes et inhibiteurs), Protéines virales (métabolisme), Pyrrolidones (), Pyrrolidones (pharmacologie), Rhinovirus (), Sites de fixation, Structure tertiaire des protéines, Syndrome respiratoire aigu sévère (virologie), Virus du SRAS (), Virus du SRAS (enzymologie).
MESH :
- antagonistes et inhibiteurs : Protéines virales.
- enzymologie : Virus du SRAS.
- métabolisme : Cysteine endopeptidases, Inhibiteurs de protéases, Protéines virales.
- pharmacologie : Inhibiteurs de protéases, Isoxazoles, Pyrrolidones.
- virologie : Syndrome respiratoire aigu sévère.
- Humains, Inhibiteurs de protéases, Isoxazoles, Pyrrolidones, Rhinovirus, Sites de fixation, Structure tertiaire des protéines, Virus du SRAS.

English descriptors

KwdEn :
- Binding Sites, Cysteine Endopeptidases (metabolism), Humans, Isoxazoles (chemistry), Isoxazoles (pharmacology), Protease Inhibitors (chemistry), Protease Inhibitors (metabolism), Protease Inhibitors (pharmacology), Protein Structure, Tertiary, Pyrrolidinones (chemistry), Pyrrolidinones (pharmacology), Rhinovirus (drug effects), SARS Virus (drug effects), SARS Virus (enzymology), Severe Acute Respiratory Syndrome (virology), Viral Proteins (antagonists & inhibitors), Viral Proteins (metabolism).
MESH :
- chemical , antagonists & inhibitors : Viral Proteins.
- chemical , chemistry : Isoxazoles, Protease Inhibitors, Pyrrolidinones.
- chemical , metabolism : Cysteine Endopeptidases, Protease Inhibitors, Viral Proteins.
- chemical , pharmacology : Isoxazoles, Protease Inhibitors, Pyrrolidinones.
- drug effects : Rhinovirus, SARS Virus.
- enzymology : SARS Virus.
- virology : Severe Acute Respiratory Syndrome.
- Binding Sites, Humans, Protein Structure, Tertiary.

DOI: 10.1007/s13238-013-2841-3
PubMed: 23549610

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Le document en format XML

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<affiliation wicri:level="1"><nlm:affiliation>College of Pharmacy and State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.</nlm:affiliation>
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The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease.

The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease.

Source :

Descripteurs français

English descriptors

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki