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Substrate specificity and rational design of peptidomimetic inhibitors for SARS coronavirus main protease.

Identifieur interne : 000F30 ( PubMed/Curation ); précédent : 000F29; suivant : 000F31

Substrate specificity and rational design of peptidomimetic inhibitors for SARS coronavirus main protease.

Auteurs : K B Wong [Hong Kong] ; D C C. Wan [Hong Kong] ; H F Chow [Hong Kong]

Source :

Hong Kong medical journal = Xianggang yi xue za zhi [ 1024-2708 ] ; 2014.

RBID : pubmed:25224113

Descripteurs français

KwdFr :
- Acides aminés, Concentration inhibitrice 50, Conception de médicament, Cysteine endopeptidases, Inhibiteurs de protéases (synthèse chimique), Oligopeptides (synthèse chimique), Peptidomimétiques (synthèse chimique), Protéines virales (antagonistes et inhibiteurs), Spécificité du substrat, Structure moléculaire, Virus du SRAS (enzymologie).
MESH :
- antagonistes et inhibiteurs : Protéines virales.
- enzymologie : Virus du SRAS.
- synthèse chimique : Inhibiteurs de protéases, Oligopeptides, Peptidomimétiques.
- Acides aminés, Concentration inhibitrice 50, Conception de médicament, Cysteine endopeptidases, Spécificité du substrat, Structure moléculaire.

English descriptors

KwdEn :
- Amino Acids, Cysteine Endopeptidases, Drug Design, Inhibitory Concentration 50, Molecular Structure, Oligopeptides (chemical synthesis), Peptidomimetics (chemical synthesis), Protease Inhibitors (chemical synthesis), SARS Virus (enzymology), Substrate Specificity, Viral Proteins (antagonists & inhibitors).
MESH :
- chemical , antagonists & inhibitors : Viral Proteins.
- chemical , chemical synthesis : Oligopeptides, Peptidomimetics, Protease Inhibitors.
- chemical : Amino Acids, Cysteine Endopeptidases.
- enzymology : SARS Virus.
- Drug Design, Inhibitory Concentration 50, Molecular Structure, Substrate Specificity.

PubMed: 25224113

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pubmed:25224113

Le document en format XML

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<author><name sortKey="Wan, D C C" sort="Wan, D C C" uniqKey="Wan D" first="D C C" last="Wan">D C C. Wan</name>
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<author><name sortKey="Chow, H F" sort="Chow, H F" uniqKey="Chow H" first="H F" last="Chow">H F Chow</name>
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<term>Molecular Structure</term>
<term>Oligopeptides (chemical synthesis)</term>
<term>Peptidomimetics (chemical synthesis)</term>
<term>Protease Inhibitors (chemical synthesis)</term>
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<term>Structure moléculaire</term>
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<term>Concentration inhibitrice 50</term>
<term>Conception de médicament</term>
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<term>Spécificité du substrat</term>
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<DateRevised><Year>2020</Year>
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Substrate specificity and rational design of peptidomimetic inhibitors for SARS coronavirus main protease.

Substrate specificity and rational design of peptidomimetic inhibitors for SARS coronavirus main protease.

Source :

Descripteurs français

English descriptors

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki