SARS and MERS: recent insights into emerging coronaviruses.
Identifieur interne : 000C34 ( PubMed/Curation ); précédent : 000C33; suivant : 000C35SARS and MERS: recent insights into emerging coronaviruses.
Auteurs : Emmie De Wit [États-Unis] ; Neeltje Van Doremalen [États-Unis] ; Darryl Falzarano [Canada] ; Vincent J. Munster [États-Unis]Source :
- Nature reviews. Microbiology [ 1740-1534 ] ; 2016.
Descripteurs français
- KwdFr :
- Animaux, Chameaux (virologie), Coronavirus du syndrome respiratoire du Moyen-Orient (pathogénicité), Coronavirus du syndrome respiratoire du Moyen-Orient (physiologie), Coronavirus du syndrome respiratoire du Moyen-Orient (ultrastructure), Flambées de maladies (), Humains, Infection croisée, Infections à coronavirus (), Infections à coronavirus (immunologie), Infections à coronavirus (transmission), Infections à coronavirus (virologie), Maladies transmissibles émergentes (), Maladies transmissibles émergentes (virologie), Pandémies (), Réplication virale, Syndrome respiratoire aigu sévère (immunologie), Syndrome respiratoire aigu sévère (transmission), Syndrome respiratoire aigu sévère (virologie), Virus du SRAS (pathogénicité), Virus du SRAS (physiologie), Virus du SRAS (ultrastructure), Voyage, Échappement immunitaire.
- MESH :
- immunologie : Infections à coronavirus, Syndrome respiratoire aigu sévère.
- pathogénicité : Coronavirus du syndrome respiratoire du Moyen-Orient, Virus du SRAS.
- physiologie : Coronavirus du syndrome respiratoire du Moyen-Orient, Virus du SRAS.
- virologie : Chameaux, Infections à coronavirus, Maladies transmissibles émergentes, Syndrome respiratoire aigu sévère.
- Animaux, Coronavirus du syndrome respiratoire du Moyen-Orient, Flambées de maladies, Humains, Infection croisée, Infections à coronavirus, Maladies transmissibles émergentes, Pandémies, Réplication virale, Syndrome respiratoire aigu sévère, Virus du SRAS, Voyage, Échappement immunitaire.
English descriptors
- KwdEn :
- Animals, Camelus (virology), Communicable Diseases, Emerging (prevention & control), Communicable Diseases, Emerging (virology), Coronavirus Infections (immunology), Coronavirus Infections (therapy), Coronavirus Infections (transmission), Coronavirus Infections (virology), Cross Infection, Disease Outbreaks (prevention & control), Humans, Immune Evasion, Middle East Respiratory Syndrome Coronavirus (pathogenicity), Middle East Respiratory Syndrome Coronavirus (physiology), Middle East Respiratory Syndrome Coronavirus (ultrastructure), Pandemics (prevention & control), SARS Virus (pathogenicity), SARS Virus (physiology), SARS Virus (ultrastructure), Severe Acute Respiratory Syndrome (immunology), Severe Acute Respiratory Syndrome (transmission), Severe Acute Respiratory Syndrome (virology), Travel, Virus Replication.
- MESH :
- immunology : Coronavirus Infections, Severe Acute Respiratory Syndrome.
- pathogenicity : Middle East Respiratory Syndrome Coronavirus, SARS Virus.
- physiology : Middle East Respiratory Syndrome Coronavirus, SARS Virus.
- prevention & control : Communicable Diseases, Emerging, Disease Outbreaks, Pandemics.
- therapy : Coronavirus Infections.
- transmission : Coronavirus Infections, Severe Acute Respiratory Syndrome.
- ultrastructure : Middle East Respiratory Syndrome Coronavirus, SARS Virus.
- virology : Camelus, Communicable Diseases, Emerging, Coronavirus Infections, Severe Acute Respiratory Syndrome.
- Animals, Cross Infection, Humans, Immune Evasion, Travel, Virus Replication.
Abstract
The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronavirus into the human population in the twenty-first century. The continuing introductions of MERS-CoV from dromedary camels, the subsequent travel-related viral spread, the unprecedented nosocomial outbreaks and the high case-fatality rates highlight the need for prophylactic and therapeutic measures. Scientific advancements since the 2002-2003 severe acute respiratory syndrome coronavirus (SARS-CoV) pandemic allowed for rapid progress in our understanding of the epidemiology and pathogenesis of MERS-CoV and the development of therapeutics. In this Review, we detail our present understanding of the transmission and pathogenesis of SARS-CoV and MERS-CoV, and discuss the current state of development of measures to combat emerging coronaviruses.
DOI: 10.1038/nrmicro.2016.81
PubMed: 27344959
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émergentes</term><term>Pandémies</term><term>Réplication virale</term><term>Syndrome respiratoire aigu sévère</term><term>Virus du SRAS</term><term>Voyage</term><term>Échappement immunitaire</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronavirus into the human population in the twenty-first century. The continuing introductions of MERS-CoV from dromedary camels, the subsequent travel-related viral spread, the unprecedented nosocomial outbreaks and the high case-fatality rates highlight the need for prophylactic and therapeutic measures. Scientific advancements since the 2002-2003 severe acute respiratory syndrome coronavirus (SARS-CoV) pandemic allowed for rapid progress in our understanding of the epidemiology and pathogenesis of MERS-CoV and the development of therapeutics. In this Review, we detail our present understanding of the transmission and pathogenesis of SARS-CoV and MERS-CoV, and discuss the current state of development of measures to combat emerging coronaviruses.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27344959</PMID><DateCompleted><Year>2017</Year><Month>05</Month><Day>10</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>27</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1740-1534</ISSN><JournalIssue CitedMedium="Internet"><Volume>14</Volume><Issue>8</Issue><PubDate><Year>2016</Year><Month>08</Month></PubDate></JournalIssue><Title>Nature reviews. Microbiology</Title><ISOAbbreviation>Nat. Rev. Microbiol.</ISOAbbreviation></Journal><ArticleTitle>SARS and MERS: recent insights into emerging coronaviruses.</ArticleTitle><Pagination><MedlinePgn>523-34</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/nrmicro.2016.81</ELocationID><Abstract><AbstractText>The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronavirus into the human population in the twenty-first century. The continuing introductions of MERS-CoV from dromedary camels, the subsequent travel-related viral spread, the unprecedented nosocomial outbreaks and the high case-fatality rates highlight the need for prophylactic and therapeutic measures. Scientific advancements since the 2002-2003 severe acute respiratory syndrome coronavirus (SARS-CoV) pandemic allowed for rapid progress in our understanding of the epidemiology and pathogenesis of MERS-CoV and the development of therapeutics. In this Review, we detail our present understanding of the transmission and pathogenesis of SARS-CoV and MERS-CoV, and discuss the current state of development of measures to combat emerging coronaviruses.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>de Wit</LastName><ForeName>Emmie</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana 59840, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Doremalen</LastName><ForeName>Neeltje</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana 59840, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Falzarano</LastName><ForeName>Darryl</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Vaccine and Infectious Disease Organization - International Vaccine Centre and Department of Veterinary Microbiology, University of Saskatchewan, 120 Veterinary Road, Saskatoon, Saskatchewan S7N 5E3, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Munster</LastName><ForeName>Vincent J</ForeName><Initials>VJ</Initials><AffiliationInfo><Affiliation>Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana 59840, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>06</Month><Day>27</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Nat Rev Microbiol</MedlineTA><NlmUniqueID>101190261</NlmUniqueID><ISSNLinking>1740-1526</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002162" MajorTopicYN="N">Camelus</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D021821" MajorTopicYN="N">Communicable Diseases, Emerging</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003428" MajorTopicYN="N">Cross Infection</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004196" MajorTopicYN="N">Disease Outbreaks</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D057131" MajorTopicYN="N">Immune Evasion</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D065207" MajorTopicYN="N">Middle East Respiratory Syndrome Coronavirus</DescriptorName><QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName><QualifierName UI="Q000648" MajorTopicYN="N">ultrastructure</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName><QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName><QualifierName UI="Q000648" MajorTopicYN="N">ultrastructure</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName><QualifierName UI="Q000821" 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