Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target.
Identifieur interne : 000708 ( PubMed/Curation ); précédent : 000707; suivant : 000709Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target.
Auteurs : Haibo Zhang [Canada] ; Josef M. Penninger [Canada] ; Yimin Li [République populaire de Chine] ; Nanshan Zhong [République populaire de Chine] ; Arthur S. Slutsky [Canada]Source :
- Intensive care medicine [ 1432-1238 ] ; 2020.
Descripteurs français
- KwdFr :
- ARN viral, Glycoprotéine de spicule des coronavirus, Humains, Peptidyl-Dipeptidase A, Pneumocytes (métabolisme), Protéines de l'enveloppe virale (métabolisme), Récepteurs viraux (métabolisme), Syndrome de détresse respiratoire de l'adulte (traitement médicamenteux), Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (enzymologie), Syndrome respiratoire aigu sévère (virologie).
- MESH :
- enzymologie : Syndrome respiratoire aigu sévère.
- métabolisme : Pneumocytes, Protéines de l'enveloppe virale, Récepteurs viraux.
- traitement médicamenteux : Syndrome de détresse respiratoire de l'adulte.
- virologie : Syndrome respiratoire aigu sévère.
- ARN viral, Glycoprotéine de spicule des coronavirus, Humains, Peptidyl-Dipeptidase A, Syndrome respiratoire aigu sévère.
English descriptors
- KwdEn :
- Alveolar Epithelial Cells (metabolism), Betacoronavirus, Humans, Peptidyl-Dipeptidase A, RNA, Viral, Receptors, Virus (metabolism), Respiratory Distress Syndrome, Adult (drug therapy), Severe Acute Respiratory Syndrome (complications), Severe Acute Respiratory Syndrome (enzymology), Severe Acute Respiratory Syndrome (virology), Spike Glycoprotein, Coronavirus, Viral Envelope Proteins (metabolism).
- MESH :
- chemical , metabolism : Receptors, Virus, Viral Envelope Proteins.
- chemical : Peptidyl-Dipeptidase A, RNA, Viral, Spike Glycoprotein, Coronavirus.
- complications : Severe Acute Respiratory Syndrome.
- drug therapy : Respiratory Distress Syndrome, Adult.
- enzymology : Severe Acute Respiratory Syndrome.
- metabolism : Alveolar Epithelial Cells.
- virology : Severe Acute Respiratory Syndrome.
- Betacoronavirus, Humans.
DOI: 10.1007/s00134-020-05985-9
PubMed: 32125455
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