SrasV1, PubMed, Corpus, bibRecord, 002A80

Programmed -1 ribosomal frameshifting in the SARS coronavirus.

Identifieur interne : 002A80 ( PubMed/Corpus ); précédent : 002A79; suivant : 002A81

Programmed -1 ribosomal frameshifting in the SARS coronavirus.

Auteurs : F. Dos Ramos ; M. Carrasco ; T. Doyle ; I. Brierley

Source :

Biochemical Society transactions [ 0300-5127 ] ; 2004.

RBID : pubmed:15506971

English descriptors

KwdEn :
- Amino Acid Sequence, Base Sequence, Frameshift Mutation (genetics), Genome, Viral, Molecular Sequence Data, Nucleic Acid Conformation, Open Reading Frames (genetics), Ribosomes (genetics), SARS Virus (genetics), Signal Transduction (genetics).
MESH :
- genetics : Frameshift Mutation, Open Reading Frames, Ribosomes, SARS Virus, Signal Transduction.
- Amino Acid Sequence, Base Sequence, Genome, Viral, Molecular Sequence Data, Nucleic Acid Conformation.

Abstract

Programmed -1 ribosomal frameshifting is an alternate mechanism of translation used by coronavirus to synthesize replication proteins encoded by two overlapping open reading frames. For some coronaviruses, the mRNA cis-acting stimulatory structures involved in this process have been characterized, but their precise contribution to ribosomal frameshifting is not completely understood. Recently, a novel coronavirus was identified as the causative agent of the severe acute respiratory syndrome. This review describes the mRNA motifs involved in programmed -1 ribosomal frameshifting in this virus.

DOI: 10.1042/BST0321081
PubMed: 15506971

Links to Exploration step

pubmed:15506971

Le document en format XML

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<author><name sortKey="Dos Ramos, F" sort="Dos Ramos, F" uniqKey="Dos Ramos F" first="F" last="Dos Ramos">F. Dos Ramos</name>
<affiliation><nlm:affiliation>Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Box 157, Cambridge CB2 2QQ, UK. fjd24@cam.ac.uk</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Carrasco, M" sort="Carrasco, M" uniqKey="Carrasco M" first="M" last="Carrasco">M. Carrasco</name>
</author>
<author><name sortKey="Doyle, T" sort="Doyle, T" uniqKey="Doyle T" first="T" last="Doyle">T. Doyle</name>
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<author><name sortKey="Brierley, I" sort="Brierley, I" uniqKey="Brierley I" first="I" last="Brierley">I. Brierley</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Programmed -1 ribosomal frameshifting in the SARS coronavirus.</title>
<author><name sortKey="Dos Ramos, F" sort="Dos Ramos, F" uniqKey="Dos Ramos F" first="F" last="Dos Ramos">F. Dos Ramos</name>
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<author><name sortKey="Carrasco, M" sort="Carrasco, M" uniqKey="Carrasco M" first="M" last="Carrasco">M. Carrasco</name>
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<author><name sortKey="Doyle, T" sort="Doyle, T" uniqKey="Doyle T" first="T" last="Doyle">T. Doyle</name>
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<author><name sortKey="Brierley, I" sort="Brierley, I" uniqKey="Brierley I" first="I" last="Brierley">I. Brierley</name>
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<term>Base Sequence</term>
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<term>Genome, Viral</term>
<term>Molecular Sequence Data</term>
<term>Nucleic Acid Conformation</term>
<term>Open Reading Frames (genetics)</term>
<term>Ribosomes (genetics)</term>
<term>SARS Virus (genetics)</term>
<term>Signal Transduction (genetics)</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Frameshift Mutation</term>
<term>Open Reading Frames</term>
<term>Ribosomes</term>
<term>SARS Virus</term>
<term>Signal Transduction</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Amino Acid Sequence</term>
<term>Base Sequence</term>
<term>Genome, Viral</term>
<term>Molecular Sequence Data</term>
<term>Nucleic Acid Conformation</term>
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<front><div type="abstract" xml:lang="en">Programmed -1 ribosomal frameshifting is an alternate mechanism of translation used by coronavirus to synthesize replication proteins encoded by two overlapping open reading frames. For some coronaviruses, the mRNA cis-acting stimulatory structures involved in this process have been characterized, but their precise contribution to ribosomal frameshifting is not completely understood. Recently, a novel coronavirus was identified as the causative agent of the severe acute respiratory syndrome. This review describes the mRNA motifs involved in programmed -1 ribosomal frameshifting in this virus.</div>
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<Month>04</Month>
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<DateRevised><Year>2017</Year>
<Month>09</Month>
<Day>22</Day>
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<JournalIssue CitedMedium="Print"><Volume>32</Volume>
<Issue>Pt 6</Issue>
<PubDate><Year>2004</Year>
<Month>Dec</Month>
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<Title>Biochemical Society transactions</Title>
<ISOAbbreviation>Biochem. Soc. Trans.</ISOAbbreviation>
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<ArticleTitle>Programmed -1 ribosomal frameshifting in the SARS coronavirus.</ArticleTitle>
<Pagination><MedlinePgn>1081-3</MedlinePgn>
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<Abstract><AbstractText>Programmed -1 ribosomal frameshifting is an alternate mechanism of translation used by coronavirus to synthesize replication proteins encoded by two overlapping open reading frames. For some coronaviruses, the mRNA cis-acting stimulatory structures involved in this process have been characterized, but their precise contribution to ribosomal frameshifting is not completely understood. Recently, a novel coronavirus was identified as the causative agent of the severe acute respiratory syndrome. This review describes the mRNA motifs involved in programmed -1 ribosomal frameshifting in this virus.</AbstractText>
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<MeshHeading><DescriptorName UI="D001483" MajorTopicYN="N">Base Sequence</DescriptorName>
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<MeshHeading><DescriptorName UI="D012270" MajorTopicYN="N">Ribosomes</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
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<MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
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<MeshHeading><DescriptorName UI="D015398" MajorTopicYN="N">Signal Transduction</DescriptorName>
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Programmed -1 ribosomal frameshifting in the SARS coronavirus.

Programmed -1 ribosomal frameshifting in the SARS coronavirus.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki