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[Study of laboratory characteristic of 4 patients with sporadic severe acute respiratory syndrome in 2004].

Identifieur interne : 002677 ( PubMed/Corpus ); précédent : 002676; suivant : 002678

[Study of laboratory characteristic of 4 patients with sporadic severe acute respiratory syndrome in 2004].

Auteurs : Yu-Juan Guan ; Xiao-Ping Tang ; Fu-Chun Zhang ; Yan-Qing Chen ; Chi-Biao Yin ; Yi-Min Li ; Nan-Shan Zhong

Source :

RBID : pubmed:15970094

English descriptors

Abstract

To analyze the laboratory characteristics of patients with sporadic severe acute respiratory syndrome (SARS) in China.

PubMed: 15970094

Links to Exploration step

pubmed:15970094

Le document en format XML

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<title xml:lang="en">[Study of laboratory characteristic of 4 patients with sporadic severe acute respiratory syndrome in 2004].</title>
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<name sortKey="Guan, Yu Juan" sort="Guan, Yu Juan" uniqKey="Guan Y" first="Yu-Juan" last="Guan">Yu-Juan Guan</name>
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<nlm:affiliation>The Eighth People's Hospital of Guangzhou, Guangzhou 510060, Guangdong, China. zhouguand@hotmail.com</nlm:affiliation>
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<name sortKey="Tang, Xiao Ping" sort="Tang, Xiao Ping" uniqKey="Tang X" first="Xiao-Ping" last="Tang">Xiao-Ping Tang</name>
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<name sortKey="Zhang, Fu Chun" sort="Zhang, Fu Chun" uniqKey="Zhang F" first="Fu-Chun" last="Zhang">Fu-Chun Zhang</name>
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<name sortKey="Chen, Yan Qing" sort="Chen, Yan Qing" uniqKey="Chen Y" first="Yan-Qing" last="Chen">Yan-Qing Chen</name>
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<name sortKey="Yin, Chi Biao" sort="Yin, Chi Biao" uniqKey="Yin C" first="Chi-Biao" last="Yin">Chi-Biao Yin</name>
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<name sortKey="Li, Yi Min" sort="Li, Yi Min" uniqKey="Li Y" first="Yi-Min" last="Li">Yi-Min Li</name>
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<name sortKey="Zhong, Nan Shan" sort="Zhong, Nan Shan" uniqKey="Zhong N" first="Nan-Shan" last="Zhong">Nan-Shan Zhong</name>
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<name sortKey="Guan, Yu Juan" sort="Guan, Yu Juan" uniqKey="Guan Y" first="Yu-Juan" last="Guan">Yu-Juan Guan</name>
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<name sortKey="Zhang, Fu Chun" sort="Zhang, Fu Chun" uniqKey="Zhang F" first="Fu-Chun" last="Zhang">Fu-Chun Zhang</name>
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<name sortKey="Chen, Yan Qing" sort="Chen, Yan Qing" uniqKey="Chen Y" first="Yan-Qing" last="Chen">Yan-Qing Chen</name>
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<name sortKey="Yin, Chi Biao" sort="Yin, Chi Biao" uniqKey="Yin C" first="Chi-Biao" last="Yin">Chi-Biao Yin</name>
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<name sortKey="Li, Yi Min" sort="Li, Yi Min" uniqKey="Li Y" first="Yi-Min" last="Li">Yi-Min Li</name>
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<name sortKey="Zhong, Nan Shan" sort="Zhong, Nan Shan" uniqKey="Zhong N" first="Nan-Shan" last="Zhong">Nan-Shan Zhong</name>
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<title level="j">Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue</title>
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<term>China (epidemiology)</term>
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<term>Humans</term>
<term>Male</term>
<term>SARS Virus (pathogenicity)</term>
<term>Severe Acute Respiratory Syndrome (blood)</term>
<term>Severe Acute Respiratory Syndrome (epidemiology)</term>
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<term>China</term>
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<term>Severe Acute Respiratory Syndrome</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Severe Acute Respiratory Syndrome</term>
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<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en">
<term>SARS Virus</term>
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<term>Female</term>
<term>Humans</term>
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<div type="abstract" xml:lang="en">To analyze the laboratory characteristics of patients with sporadic severe acute respiratory syndrome (SARS) in China.</div>
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<DateCompleted>
<Year>2009</Year>
<Month>12</Month>
<Day>15</Day>
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<DateRevised>
<Year>2005</Year>
<Month>06</Month>
<Day>22</Day>
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<ISSN IssnType="Print">1003-0603</ISSN>
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<Volume>17</Volume>
<Issue>6</Issue>
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<Year>2005</Year>
<Month>Jun</Month>
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<Title>Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue</Title>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To analyze the laboratory characteristics of patients with sporadic severe acute respiratory syndrome (SARS) in China.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The laboratory findings of the 4 cases with SARS occurring in Guangzhou, People's Republic of China, in 2004 were analyzed and compared with that during epidemic.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Leukopenia and lymphocytopenia were seen in all the patients. Two patients had slightly decreased peripheral blood T lymphocyte count. Alanine aminotransferase (ALT) and aspartate transaminase (AST) levels increased slightly in 3 patients. No hypoxemia was seen in all the patients. Both SARS-IgM and IgG sero-conversion occurred earlier in all the patients with the titer increased more than 4-fold shortly. Neutralization test was positive in all the patients. SARS coronary virus (SARS-CoV) RNA was detected by polymerase chain reaction (PCR) in pharyngeal swabs only in 1 patient.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The 4 sporadic SARS patients in 2004 have milder manifestations, shorter course of disease with no complications during an epidemic, compared with patients seen previously. The change in laboratory findings is less than that, which might be attributable to milder virulence of the SARS-CoV. The antibody appears earlier in these patients. The SARS-CoV is eliminated rapidly.</AbstractText>
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