Critical care lessons from severe acute respiratory syndrome.
Identifieur interne : 002D65 ( PubMed/Checkpoint ); précédent : 002D64; suivant : 002D66Critical care lessons from severe acute respiratory syndrome.
Auteurs : Stephen E. Lapinsky [Canada] ; John T. GrantonSource :
- Current opinion in critical care [ 1070-5295 ] ; 2004.
Descripteurs français
- KwdFr :
- Antiviraux (usage thérapeutique), Chine (épidémiologie), Hong Kong (épidémiologie), Hormones corticosurrénaliennes (usage thérapeutique), Humains, Lutte contre l'infection, Ontario (épidémiologie), Pronostic, Résultat thérapeutique, Singapour (épidémiologie), Soins de réanimation, Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (mortalité), Syndrome respiratoire aigu sévère (transmission).
- MESH :
- mortalité : Syndrome respiratoire aigu sévère.
- usage thérapeutique : Antiviraux, Hormones corticosurrénaliennes, Syndrome respiratoire aigu sévère.
- épidémiologie : Chine, Hong Kong, Ontario, Singapour.
- Humains, Lutte contre l'infection, Pronostic, Résultat thérapeutique, Soins de réanimation, Syndrome respiratoire aigu sévère.
- Wicri :
- geographic : République populaire de Chine, Hong Kong, Singapour.
English descriptors
- KwdEn :
- Adrenal Cortex Hormones (therapeutic use), Antiviral Agents (therapeutic use), China (epidemiology), Critical Care, Hong Kong (epidemiology), Humans, Infection Control, Ontario (epidemiology), Prognosis, Severe Acute Respiratory Syndrome (mortality), Severe Acute Respiratory Syndrome (therapy), Severe Acute Respiratory Syndrome (transmission), Singapore (epidemiology), Treatment Outcome.
- MESH :
- chemical , therapeutic use : Adrenal Cortex Hormones, Antiviral Agents.
- geographic , epidemiology : China, Hong Kong, Ontario, Singapore.
- mortality : Severe Acute Respiratory Syndrome.
- therapy : Severe Acute Respiratory Syndrome.
- transmission : Severe Acute Respiratory Syndrome.
- Critical Care, Humans, Infection Control, Prognosis, Treatment Outcome.
Abstract
Severe acute respiratory syndrome (SARS) is a new disease that caused large outbreaks in several countries in the first half of 2003, resulting in infection in more than 8000 people and more than 900 deaths. During that time, a large body of literature rapidly emerged describing the clinical disease, the etiologic viral agent, and management options. This paper reviews the current status of this knowledge base, with particular reference to the critically ill patient.
DOI: 10.1097/00075198-200402000-00009
PubMed: 15166850
Affiliations:
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pubmed:15166850Le document en format XML
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<wicri:regionArea>Mount Sinai Hospital, University Health Network, and the Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario</wicri:regionArea>
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<term>Critical Care</term>
<term>Hong Kong (epidemiology)</term>
<term>Humans</term>
<term>Infection Control</term>
<term>Ontario (epidemiology)</term>
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<term>Severe Acute Respiratory Syndrome (therapy)</term>
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<term>Chine (épidémiologie)</term>
<term>Hong Kong (épidémiologie)</term>
<term>Hormones corticosurrénaliennes (usage thérapeutique)</term>
<term>Humains</term>
<term>Lutte contre l'infection</term>
<term>Ontario (épidémiologie)</term>
<term>Pronostic</term>
<term>Résultat thérapeutique</term>
<term>Singapour (épidémiologie)</term>
<term>Soins de réanimation</term>
<term>Syndrome respiratoire aigu sévère ()</term>
<term>Syndrome respiratoire aigu sévère (mortalité)</term>
<term>Syndrome respiratoire aigu sévère (transmission)</term>
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<term>Antiviral Agents</term>
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<term>Hong Kong</term>
<term>Ontario</term>
<term>Singapore</term>
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<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
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<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term>
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<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term>
<term>Hormones corticosurrénaliennes</term>
<term>Syndrome respiratoire aigu sévère</term>
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<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Chine</term>
<term>Hong Kong</term>
<term>Ontario</term>
<term>Singapour</term>
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<term>Humans</term>
<term>Infection Control</term>
<term>Prognosis</term>
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<term>Résultat thérapeutique</term>
<term>Soins de réanimation</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>République populaire de Chine</term>
<term>Hong Kong</term>
<term>Singapour</term>
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<front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome (SARS) is a new disease that caused large outbreaks in several countries in the first half of 2003, resulting in infection in more than 8000 people and more than 900 deaths. During that time, a large body of literature rapidly emerged describing the clinical disease, the etiologic viral agent, and management options. This paper reviews the current status of this knowledge base, with particular reference to the critically ill patient.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">15166850</PMID>
<DateCompleted><Year>2004</Year>
<Month>06</Month>
<Day>23</Day>
</DateCompleted>
<DateRevised><Year>2019</Year>
<Month>11</Month>
<Day>08</Day>
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<Article PubModel="Print"><Journal><ISSN IssnType="Print">1070-5295</ISSN>
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<Issue>1</Issue>
<PubDate><Year>2004</Year>
<Month>Feb</Month>
</PubDate>
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<Title>Current opinion in critical care</Title>
<ISOAbbreviation>Curr Opin Crit Care</ISOAbbreviation>
</Journal>
<ArticleTitle>Critical care lessons from severe acute respiratory syndrome.</ArticleTitle>
<Pagination><MedlinePgn>53-8</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="PURPOSE OF REVIEW" NlmCategory="OBJECTIVE">Severe acute respiratory syndrome (SARS) is a new disease that caused large outbreaks in several countries in the first half of 2003, resulting in infection in more than 8000 people and more than 900 deaths. During that time, a large body of literature rapidly emerged describing the clinical disease, the etiologic viral agent, and management options. This paper reviews the current status of this knowledge base, with particular reference to the critically ill patient.</AbstractText>
<AbstractText Label="RECENT FINDINGS" NlmCategory="RESULTS">Case series of patients from Hong Kong, China, Singapore, and Toronto have characterized the disease with remarkable uniformity. A similarly consistent picture of the SARS patient with respiratory failure has emerged from studies from Toronto and Singapore. Worldwide collaboration led to the rapid identification and gene sequencing of the etiologic virus, SARS-CoV.</AbstractText>
<AbstractText Label="SUMMARY" NlmCategory="CONCLUSIONS">SARS is a predominantly respiratory illness, spread through droplets from respiratory secretions and possibly via a fecal-oral route. A small number of "super-spreaders" appear to have contributed to the rapid proliferation of the disease. Infection control precautions are an essential component of management. Approximately 20% of patients develop progressive pulmonary infiltrates and respiratory failure, and the mortality rate is as high as 10%. Treatment strategies with antiviral agents such as ribavirin have not clearly demonstrated a benefit, but high-dose corticosteroids appear to be beneficial in patients with progressive disease. The recent outbreaks highlighted the potential for this disease to overwhelm critical care resources, by the volume of patients and loss of healthcare workers to illness and quarantine.</AbstractText>
</Abstract>
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<ForeName>Stephen E</ForeName>
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<AffiliationInfo><Affiliation>Mount Sinai Hospital, University Health Network, and the Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario, Canada. Stephen.lapinsky@utoronto.ca</Affiliation>
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<MeshHeading><DescriptorName UI="D017053" MajorTopicYN="Y">Infection Control</DescriptorName>
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<MeshHeading><DescriptorName UI="D011379" MajorTopicYN="N">Prognosis</DescriptorName>
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