SrasV1, PubMed, Checkpoint, bibRecord, 001F67

Synthesis of stilbene derivatives with inhibition of SARS coronavirus replication.

Identifieur interne : 001F67 ( PubMed/Checkpoint ); précédent : 001F66; suivant : 001F68

Synthesis of stilbene derivatives with inhibition of SARS coronavirus replication.

Auteurs : Yue-Qing Li [République populaire de Chine] ; Ze-Lin Li ; Wei-Jie Zhao ; Rui-Xing Wen ; Qing-Wei Meng ; Yi Zeng

Source :

European journal of medicinal chemistry [ 0223-5234 ] ; 2006.

RBID : pubmed:16875760

Descripteurs français

KwdFr :
- Animaux, Cellules Vero, Relation structure-activité, Réplication virale (), Stilbènes (), Stilbènes (pharmacologie), Stilbènes (synthèse chimique), Structure moléculaire, Virus du SRAS (), Virus du SRAS (physiologie).
MESH :
- pharmacologie : Stilbènes.
- physiologie : Virus du SRAS.
- synthèse chimique : Stilbènes.
- Animaux, Cellules Vero, Relation structure-activité, Réplication virale, Stilbènes, Structure moléculaire, Virus du SRAS.

English descriptors

KwdEn :
- Animals, Chlorocebus aethiops, Molecular Structure, SARS Virus (drug effects), SARS Virus (physiology), Stilbenes (chemical synthesis), Stilbenes (chemistry), Stilbenes (pharmacology), Structure-Activity Relationship, Vero Cells, Virus Replication (drug effects).
MESH :
- chemical , chemical synthesis : Stilbenes.
- chemical , chemistry : Stilbenes.
- drug effects : SARS Virus, Virus Replication.
- chemical , pharmacology : Stilbenes.
- physiology : SARS Virus.
- Animals, Chlorocebus aethiops, Molecular Structure, Structure-Activity Relationship, Vero Cells.

Abstract

Stilbene derivatives have wide range of activities. In an effort to find other potential activities of this kind of compounds, 17 derivatives, including resveratrol, were synthesized. Twelve of them were evaluated for their antiviral potential against severe acute respiratory syndrome (SARS)-CoV-induced cytopathicity in Vero E6 cell culture. The result showed that SARS virus was totally inhibited by compounds 17 and 19 (
DOI: 10.1016/j.ejmech.2006.03.024
PubMed: 16875760

Affiliations:

République populaire de Chine

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Le document en format XML

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<term>Relation structure-activité</term>
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<front><div type="abstract" xml:lang="en">Stilbene derivatives have wide range of activities. In an effort to find other potential activities of this kind of compounds, 17 derivatives, including resveratrol, were synthesized. Twelve of them were evaluated for their antiviral potential against severe acute respiratory syndrome (SARS)-CoV-induced cytopathicity in Vero E6 cell culture. The result showed that SARS virus was totally inhibited by compounds 17 and 19 (</div>
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Synthesis of stilbene derivatives with inhibition of SARS coronavirus replication.

Synthesis of stilbene derivatives with inhibition of SARS coronavirus replication.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki