[SARS vaccines].
Identifieur interne : 001961 ( PubMed/Checkpoint ); précédent : 001960; suivant : 001962[SARS vaccines].
Auteurs : Fumihiro TaguchiSource :
- Nihon rinsho. Japanese journal of clinical medicine [ 0047-1852 ] ; 2008.
Descripteurs français
- KwdFr :
- MESH :
- effets indésirables : Vaccins antiviraux.
- immunologie : Virus du SRAS.
- virologie : Syndrome respiratoire aigu sévère.
- Animaux, Conception de médicament, Humains, Protéines virales, Syndrome respiratoire aigu sévère, Vaccins atténués, Vaccins sous-unitaires, Vaccins à ADN, Vecteurs génétiques.
English descriptors
- KwdEn :
- MESH :
- chemical , adverse effects : Viral Vaccines.
- chemical : Vaccines, Attenuated, Vaccines, DNA, Vaccines, Subunit, Viral Proteins.
- immunology : SARS Virus.
- prevention & control : Severe Acute Respiratory Syndrome.
- virology : Severe Acute Respiratory Syndrome.
- Animals, Drug Design, Genetic Vectors, Humans.
Abstract
Severe acute respiratory syndrome (SARS) is an emerging disease derived from wild animals and is highly pathogenic with a high mortality. A novel coronavirus SARS coronavirus was identified to be a causative agent for SARS. Since its discovery, many trials have been executed to establish the prophylactic and therapeutics toward SARS using laboratory animals. A number of different types of vaccines, such as inactivated virus vaccine, subunit vaccine, DNA vaccine and vaccine using viral expression vector as well as attenuated live vaccine so far reported indicate that neutralizing antibodies play an important role for protection. However, vaccine applicable to humans with the high efficacy and safety has not yet been reported.
PubMed: 18939499
Affiliations:
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pubmed:18939499Le document en format XML
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<affiliation><nlm:affiliation>Department of Virology III, National Institute of Infectious Diseases.</nlm:affiliation>
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<term>Humains</term>
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<term>Syndrome respiratoire aigu sévère</term>
<term>Vaccins atténués</term>
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<front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome (SARS) is an emerging disease derived from wild animals and is highly pathogenic with a high mortality. A novel coronavirus SARS coronavirus was identified to be a causative agent for SARS. Since its discovery, many trials have been executed to establish the prophylactic and therapeutics toward SARS using laboratory animals. A number of different types of vaccines, such as inactivated virus vaccine, subunit vaccine, DNA vaccine and vaccine using viral expression vector as well as attenuated live vaccine so far reported indicate that neutralizing antibodies play an important role for protection. However, vaccine applicable to humans with the high efficacy and safety has not yet been reported.</div>
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<Abstract><AbstractText>Severe acute respiratory syndrome (SARS) is an emerging disease derived from wild animals and is highly pathogenic with a high mortality. A novel coronavirus SARS coronavirus was identified to be a causative agent for SARS. Since its discovery, many trials have been executed to establish the prophylactic and therapeutics toward SARS using laboratory animals. A number of different types of vaccines, such as inactivated virus vaccine, subunit vaccine, DNA vaccine and vaccine using viral expression vector as well as attenuated live vaccine so far reported indicate that neutralizing antibodies play an important role for protection. However, vaccine applicable to humans with the high efficacy and safety has not yet been reported.</AbstractText>
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