[SARS vaccines].
Identifieur interne : 001A47 ( PubMed/Corpus ); précédent : 001A46; suivant : 001A48[SARS vaccines].
Auteurs : Fumihiro TaguchiSource :
- Nihon rinsho. Japanese journal of clinical medicine [ 0047-1852 ] ; 2008.
English descriptors
- KwdEn :
- MESH :
- chemical , adverse effects : Viral Vaccines.
- chemical : Vaccines, Attenuated, Vaccines, DNA, Vaccines, Subunit, Viral Proteins.
- immunology : SARS Virus.
- prevention & control : Severe Acute Respiratory Syndrome.
- virology : Severe Acute Respiratory Syndrome.
- Animals, Drug Design, Genetic Vectors, Humans.
Abstract
Severe acute respiratory syndrome (SARS) is an emerging disease derived from wild animals and is highly pathogenic with a high mortality. A novel coronavirus SARS coronavirus was identified to be a causative agent for SARS. Since its discovery, many trials have been executed to establish the prophylactic and therapeutics toward SARS using laboratory animals. A number of different types of vaccines, such as inactivated virus vaccine, subunit vaccine, DNA vaccine and vaccine using viral expression vector as well as attenuated live vaccine so far reported indicate that neutralizing antibodies play an important role for protection. However, vaccine applicable to humans with the high efficacy and safety has not yet been reported.
PubMed: 18939499
Links to Exploration step
pubmed:18939499Le document en format XML
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<author><name sortKey="Taguchi, Fumihiro" sort="Taguchi, Fumihiro" uniqKey="Taguchi F" first="Fumihiro" last="Taguchi">Fumihiro Taguchi</name>
<affiliation><nlm:affiliation>Department of Virology III, National Institute of Infectious Diseases.</nlm:affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">[SARS vaccines].</title>
<author><name sortKey="Taguchi, Fumihiro" sort="Taguchi, Fumihiro" uniqKey="Taguchi F" first="Fumihiro" last="Taguchi">Fumihiro Taguchi</name>
<affiliation><nlm:affiliation>Department of Virology III, National Institute of Infectious Diseases.</nlm:affiliation>
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<series><title level="j">Nihon rinsho. Japanese journal of clinical medicine</title>
<idno type="ISSN">0047-1852</idno>
<imprint><date when="2008" type="published">2008</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Drug Design</term>
<term>Genetic Vectors</term>
<term>Humans</term>
<term>SARS Virus (immunology)</term>
<term>Severe Acute Respiratory Syndrome (prevention & control)</term>
<term>Severe Acute Respiratory Syndrome (virology)</term>
<term>Vaccines, Attenuated</term>
<term>Vaccines, DNA</term>
<term>Vaccines, Subunit</term>
<term>Viral Proteins</term>
<term>Viral Vaccines (adverse effects)</term>
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<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Viral Vaccines</term>
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<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Vaccines, Attenuated</term>
<term>Vaccines, DNA</term>
<term>Vaccines, Subunit</term>
<term>Viral Proteins</term>
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<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>SARS Virus</term>
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<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
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<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
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<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
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<front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome (SARS) is an emerging disease derived from wild animals and is highly pathogenic with a high mortality. A novel coronavirus SARS coronavirus was identified to be a causative agent for SARS. Since its discovery, many trials have been executed to establish the prophylactic and therapeutics toward SARS using laboratory animals. A number of different types of vaccines, such as inactivated virus vaccine, subunit vaccine, DNA vaccine and vaccine using viral expression vector as well as attenuated live vaccine so far reported indicate that neutralizing antibodies play an important role for protection. However, vaccine applicable to humans with the high efficacy and safety has not yet been reported.</div>
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<DateCompleted><Year>2008</Year>
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<Month>07</Month>
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<JournalIssue CitedMedium="Print"><Volume>66</Volume>
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<Title>Nihon rinsho. Japanese journal of clinical medicine</Title>
<ISOAbbreviation>Nippon Rinsho</ISOAbbreviation>
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<ArticleTitle>[SARS vaccines].</ArticleTitle>
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<Abstract><AbstractText>Severe acute respiratory syndrome (SARS) is an emerging disease derived from wild animals and is highly pathogenic with a high mortality. A novel coronavirus SARS coronavirus was identified to be a causative agent for SARS. Since its discovery, many trials have been executed to establish the prophylactic and therapeutics toward SARS using laboratory animals. A number of different types of vaccines, such as inactivated virus vaccine, subunit vaccine, DNA vaccine and vaccine using viral expression vector as well as attenuated live vaccine so far reported indicate that neutralizing antibodies play an important role for protection. However, vaccine applicable to humans with the high efficacy and safety has not yet been reported.</AbstractText>
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<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Taguchi</LastName>
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<NumberOfReferences>22</NumberOfReferences>
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