Understanding the T cell immune response in SARS coronavirus infection.
Identifieur interne : 001253 ( PubMed/Checkpoint ); précédent : 001252; suivant : 001254Understanding the T cell immune response in SARS coronavirus infection.
Auteurs : Hsueh-Ling Janice Oh [Singapour] ; Samuel Ken-En Gan [Singapour] ; Antonio Bertoletti [Singapour] ; Yee-Joo Tan [Singapour]Source :
- Emerging microbes & infections [ 2222-1751 ] ; 2012.
Abstract
The severe acute respiratory syndrome (SARS) epidemic started in late 2002 and swiftly spread across 5 continents with a mortality rate of around 10%. Although the epidemic was eventually controlled through the implementation of strict quarantine measures, there continues a need to investigate the SARS coronavirus (SARS-CoV) and develop interventions should it re-emerge. Numerous studies have shown that neutralizing antibodies against the virus can be found in patients infected with SARS-CoV within days upon the onset of illness and lasting up to several months. In contrast, there is little data on the kinetics of T cell responses during SARS-CoV infection and little is known about their role in the recovery process. However, recent studies in mice suggest the importance of T cells in viral clearance during SARS-CoV infection. Moreover, a growing number of studies have investigated the memory T cell responses in recovered SARS patients. This review covers the available literature on the emerging importance of T cell responses in SARS-CoV infection, particularly on the mapping of cytotoxic T lymphocyte (CTL) epitopes, longevity, polyfunctionality and human leukocyte antigen (HLA) association as well as their potential implications on treatment and vaccine development.
DOI: 10.1038/emi.2012.26
PubMed: 26038429
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Institute of Molecular and Cell Biology, Agency of Science Technology and Research (A*Star) , Singapore 138673, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Singapore Immunology Network, Agency of Science Technology and Research (AStar) , Singapore 138648, Singapore ; Institute of Molecular and Cell Biology, Agency of Science Technology and Research (A*Star) , Singapore 138673</wicri:regionArea><wicri:noRegion>Singapore 138673</wicri:noRegion></affiliation></author><author><name sortKey="Ken En Gan, Samuel" sort="Ken En Gan, Samuel" uniqKey="Ken En Gan S" first="Samuel" last="Ken-En Gan">Samuel Ken-En Gan</name><affiliation wicri:level="1"><nlm:affiliation>Bioinformatics Institute, Agency of Science Technology and Research (AStar) , Singapore 138671, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Bioinformatics Institute, Agency of Science Technology and Research (AStar) , Singapore 138671</wicri:regionArea><wicri:noRegion>Singapore 138671</wicri:noRegion></affiliation></author><author><name sortKey="Bertoletti, Antonio" sort="Bertoletti, Antonio" uniqKey="Bertoletti A" first="Antonio" last="Bertoletti">Antonio Bertoletti</name><affiliation wicri:level="1"><nlm:affiliation>Singapore Institute for Clinical Sciences, Agency of Science Technology and Research (AStar) , Singapore 117609, Singapore ; Program of Emerging Viral Diseases, Duke-NUS Graduate Medical School , Singapore 169857, Singapore ; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore , Singapore 119228, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Singapore Institute for Clinical Sciences, Agency of Science Technology and Research (AStar) , Singapore 117609, Singapore ; Program of Emerging Viral Diseases, Duke-NUS Graduate Medical School , Singapore 169857, Singapore ; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore , Singapore 119228</wicri:regionArea><wicri:noRegion>Singapore 119228</wicri:noRegion></affiliation></author><author><name sortKey="Tan, Yee Joo" sort="Tan, Yee Joo" uniqKey="Tan Y" first="Yee-Joo" last="Tan">Yee-Joo Tan</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Molecular and Cell Biology, Agency of Science Technology and Research (AStar) , Singapore 138673, Singapore ; Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore , Singapore 117597, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Institute of Molecular and Cell Biology, Agency of Science Technology and Research (AStar) , Singapore 138673, Singapore ; Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore , Singapore 117597</wicri:regionArea><wicri:noRegion>Singapore 117597</wicri:noRegion></affiliation></author></analytic><series><title level="j">Emerging microbes & infections</title><idno type="ISSN">2222-1751</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The severe acute respiratory syndrome (SARS) epidemic started in late 2002 and swiftly spread across 5 continents with a mortality rate of around 10%. Although the epidemic was eventually controlled through the implementation of strict quarantine measures, there continues a need to investigate the SARS coronavirus (SARS-CoV) and develop interventions should it re-emerge. Numerous studies have shown that neutralizing antibodies against the virus can be found in patients infected with SARS-CoV within days upon the onset of illness and lasting up to several months. In contrast, there is little data on the kinetics of T cell responses during SARS-CoV infection and little is known about their role in the recovery process. However, recent studies in mice suggest the importance of T cells in viral clearance during SARS-CoV infection. Moreover, a growing number of studies have investigated the memory T cell responses in recovered SARS patients. This review covers the available literature on the emerging importance of T cell responses in SARS-CoV infection, particularly on the mapping of cytotoxic T lymphocyte (CTL) epitopes, longevity, polyfunctionality and human leukocyte antigen (HLA) association as well as their potential implications on treatment and vaccine development. </div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">26038429</PMID><DateCompleted><Year>2015</Year><Month>06</Month><Day>03</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">2222-1751</ISSN><JournalIssue CitedMedium="Print"><Volume>1</Volume><Issue>9</Issue><PubDate><Year>2012</Year><Month>Sep</Month></PubDate></JournalIssue><Title>Emerging microbes & infections</Title><ISOAbbreviation>Emerg Microbes Infect</ISOAbbreviation></Journal><ArticleTitle>Understanding the T cell immune response in SARS coronavirus infection.</ArticleTitle><Pagination><MedlinePgn>e23</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/emi.2012.26</ELocationID><Abstract><AbstractText>The severe acute respiratory syndrome (SARS) epidemic started in late 2002 and swiftly spread across 5 continents with a mortality rate of around 10%. Although the epidemic was eventually controlled through the implementation of strict quarantine measures, there continues a need to investigate the SARS coronavirus (SARS-CoV) and develop interventions should it re-emerge. Numerous studies have shown that neutralizing antibodies against the virus can be found in patients infected with SARS-CoV within days upon the onset of illness and lasting up to several months. In contrast, there is little data on the kinetics of T cell responses during SARS-CoV infection and little is known about their role in the recovery process. However, recent studies in mice suggest the importance of T cells in viral clearance during SARS-CoV infection. Moreover, a growing number of studies have investigated the memory T cell responses in recovered SARS patients. This review covers the available literature on the emerging importance of T cell responses in SARS-CoV infection, particularly on the mapping of cytotoxic T lymphocyte (CTL) epitopes, longevity, polyfunctionality and human leukocyte antigen (HLA) association as well as their potential implications on treatment and vaccine development. </AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Janice Oh</LastName><ForeName>Hsueh-Ling</ForeName><Initials>HL</Initials><AffiliationInfo><Affiliation>Singapore Immunology Network, Agency of Science Technology and Research (AStar) , Singapore 138648, Singapore ; Institute of Molecular and Cell Biology, Agency of Science Technology and Research (A*Star) , Singapore 138673, Singapore.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ken-En Gan</LastName><ForeName>Samuel</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Bioinformatics Institute, Agency of Science Technology and Research (AStar) , Singapore 138671, Singapore.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bertoletti</LastName><ForeName>Antonio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Singapore Institute for Clinical Sciences, Agency of Science Technology and Research (AStar) , Singapore 117609, Singapore ; Program of Emerging Viral Diseases, Duke-NUS Graduate Medical School , Singapore 169857, Singapore ; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore , Singapore 119228, Singapore.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tan</LastName><ForeName>Yee-Joo</ForeName><Initials>YJ</Initials><AffiliationInfo><Affiliation>Institute of Molecular and Cell Biology, Agency of Science Technology and Research (AStar) , Singapore 138673, Singapore ; Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore , Singapore 117597, 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Oct;24(5):421-6</Citation><ArticleIdList><ArticleId IdType="pubmed">21958371</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 1997 Oct;71(10):7889-94</Citation><ArticleIdList><ArticleId IdType="pubmed">9311878</ArticleId></ArticleIdList></Reference><Reference><Citation>Semin Cancer Biol. 1996 Dec;7(6):359-71</Citation><ArticleIdList><ArticleId IdType="pubmed">9284528</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2006 Apr 1;176(7):4094-101</Citation><ArticleIdList><ArticleId IdType="pubmed">16547245</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1967-76</Citation><ArticleIdList><ArticleId IdType="pubmed">12690091</ArticleId></ArticleIdList></Reference><Reference><Citation>J Mol Biol. 2003 Aug 29;331(5):991-1004</Citation><ArticleIdList><ArticleId IdType="pubmed">12927536</ArticleId></ArticleIdList></Reference><Reference><Citation>Immunol Lett. 2004 Apr 15;92(3):237-43</Citation><ArticleIdList><ArticleId IdType="pubmed">15081618</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):14040-5</Citation><ArticleIdList><ArticleId IdType="pubmed">16169905</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2011 Jun 15;186(12):7264-8</Citation><ArticleIdList><ArticleId IdType="pubmed">21576510</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 2006 Aug 1;351(2):466-75</Citation><ArticleIdList><ArticleId IdType="pubmed">16690096</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2004 Jul 15;190(2):379-86</Citation><ArticleIdList><ArticleId IdType="pubmed">15216476</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Microbiol Infect. 2004 Jul;10(7):676-8</Citation><ArticleIdList><ArticleId IdType="pubmed">15214887</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9804-9</Citation><ArticleIdList><ArticleId IdType="pubmed">15210961</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2004 Aug 1;190(3):515-8</Citation><ArticleIdList><ArticleId IdType="pubmed">15243926</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2004 Jan 10;363(9403):99-104</Citation><ArticleIdList><ArticleId IdType="pubmed">14726162</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2001 Jul 1;184(1):16-21</Citation><ArticleIdList><ArticleId IdType="pubmed">11398104</ArticleId></ArticleIdList></Reference><Reference><Citation>Blood. 2006 Jun 15;107(12):4781-9</Citation><ArticleIdList><ArticleId IdType="pubmed">16467198</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Microbiol. 2004 Apr;42(4):1570-6</Citation><ArticleIdList><ArticleId IdType="pubmed">15071006</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Med Genet. 2003 Sep 12;4:9</Citation><ArticleIdList><ArticleId IdType="pubmed">12969506</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2004 May;78(9):4638-45</Citation><ArticleIdList><ArticleId IdType="pubmed">15078946</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Med. 2003;54:535-51</Citation><ArticleIdList><ArticleId IdType="pubmed">12525683</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2005 Oct 28;310(5748):676-9</Citation><ArticleIdList><ArticleId IdType="pubmed">16195424</ArticleId></ArticleIdList></Reference><Reference><Citation>J Gen Virol. 2007 Oct;88(Pt 10):2740-8</Citation><ArticleIdList><ArticleId IdType="pubmed">17872527</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2003 May 30;300(5624):1399-404</Citation><ArticleIdList><ArticleId IdType="pubmed">12730501</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Med. 2004 Aug;10(8):871-5</Citation><ArticleIdList><ArticleId IdType="pubmed">15247913</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2011 Sep 2;29(38):6606-13</Citation><ArticleIdList><ArticleId IdType="pubmed">21762752</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Immunol. 2009 Dec 03;10:61</Citation><ArticleIdList><ArticleId IdType="pubmed">19958537</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Microbiol Infect. 2004 Dec;10(12):1062-6</Citation><ArticleIdList><ArticleId IdType="pubmed">15606632</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2006 Dec 20;1:e24</Citation><ArticleIdList><ArticleId IdType="pubmed">17183651</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2006 Jun 5;24(23):4905-13</Citation><ArticleIdList><ArticleId IdType="pubmed">16621188</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2005 May 2;23 (24):3202-9</Citation><ArticleIdList><ArticleId IdType="pubmed">15837221</ArticleId></ArticleIdList></Reference><Reference><Citation>Blood. 2004 Jul 1;104(1):200-6</Citation><ArticleIdList><ArticleId IdType="pubmed">15016646</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Med. 2007 Jun 11;204(6):1405-16</Citation><ArticleIdList><ArticleId IdType="pubmed">17535971</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Microbiol Rev. 2007 Oct;20(4):660-94</Citation><ArticleIdList><ArticleId IdType="pubmed">17934078</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 2005 Mar 25;328(4):979-86</Citation><ArticleIdList><ArticleId IdType="pubmed">15707974</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2003 Apr 19;361(9366):1319-25</Citation><ArticleIdList><ArticleId IdType="pubmed">12711465</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2003 Oct 25;362(9393):1353-8</Citation><ArticleIdList><ArticleId IdType="pubmed">14585636</ArticleId></ArticleIdList></Reference><Reference><Citation>Antiviral Res. 2006 Nov;72(2):78-88</Citation><ArticleIdList><ArticleId IdType="pubmed">16820226</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 2005 Apr 10;334(2):160-5</Citation><ArticleIdList><ArticleId IdType="pubmed">15780866</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2010 Sep;84(18):9318-25</Citation><ArticleIdList><ArticleId IdType="pubmed">20610717</ArticleId></ArticleIdList></Reference><Reference><Citation>J Viral Hepat. 2001 May;8(3):174-9</Citation><ArticleIdList><ArticleId IdType="pubmed">11380794</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2006 Aug 15;177(4):2138-45</Citation><ArticleIdList><ArticleId IdType="pubmed">16887973</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2008 Oct 15;181(8):5490-500</Citation><ArticleIdList><ArticleId IdType="pubmed">18832706</ArticleId></ArticleIdList></Reference><Reference><Citation>Dev Comp Immunol. 2000 Mar-Apr;24(2-3):187-200</Citation><ArticleIdList><ArticleId IdType="pubmed">10717287</ArticleId></ArticleIdList></Reference><Reference><Citation>Immunology. 2010 Jun;130(2):254-61</Citation><ArticleIdList><ArticleId IdType="pubmed">20406307</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Pathog. 2009 Oct;5(10):e1000636</Citation><ArticleIdList><ArticleId IdType="pubmed">19851468</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Vaccine Immunol. 2009 Jan;16(1):73-7</Citation><ArticleIdList><ArticleId IdType="pubmed">18987164</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2004 Apr 1;172(7):4435-43</Citation><ArticleIdList><ArticleId IdType="pubmed">15034059</ArticleId></ArticleIdList></Reference><Reference><Citation>J Gen Virol. 2000 Apr;81(Pt 4):853-79</Citation><ArticleIdList><ArticleId IdType="pubmed">10725411</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2010 Sep 24;28(41):6666-74</Citation><ArticleIdList><ArticleId IdType="pubmed">20709007</ArticleId></ArticleIdList></Reference><Reference><Citation>J Gen Virol. 2006 Mar;87(Pt 3):641-50</Citation><ArticleIdList><ArticleId IdType="pubmed">16476986</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2536-41</Citation><ArticleIdList><ArticleId IdType="pubmed">14983044</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Virol. 2009;154(7):1093-9</Citation><ArticleIdList><ArticleId IdType="pubmed">19526193</ArticleId></ArticleIdList></Reference><Reference><Citation>Hepatology. 2006 Mar;43(3):563-72</Citation><ArticleIdList><ArticleId IdType="pubmed">16496339</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2009 Sep;83(18):9258-72</Citation><ArticleIdList><ArticleId IdType="pubmed">19570864</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2005 Jul 1;175(1):591-8</Citation><ArticleIdList><ArticleId IdType="pubmed">15972696</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2004 Jun;78(11):5612-8</Citation><ArticleIdList><ArticleId IdType="pubmed">15140958</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2003 Dec 6;362(9399):1895-6</Citation><ArticleIdList><ArticleId IdType="pubmed">14667748</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2006 Jan 30;24(5):652-61</Citation><ArticleIdList><ArticleId IdType="pubmed">16214268</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Mol Immunol. 2004 Jun;1(3):193-8</Citation><ArticleIdList><ArticleId IdType="pubmed">16219167</ArticleId></ArticleIdList></Reference><Reference><Citation>Tissue Antigens. 2000 Mar;55(3):280-7</Citation><ArticleIdList><ArticleId IdType="pubmed">10777106</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2003 May 30;300(5624):1394-9</Citation><ArticleIdList><ArticleId IdType="pubmed">12730500</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2011 Oct;85(20):10464-71</Citation><ArticleIdList><ArticleId IdType="pubmed">21813600</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2010 Feb;84(3):1289-301</Citation><ArticleIdList><ArticleId IdType="pubmed">19906920</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 2006 May 26;344(1):63-71</Citation><ArticleIdList><ArticleId IdType="pubmed">16630549</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1953-66</Citation><ArticleIdList><ArticleId IdType="pubmed">12690092</ArticleId></ArticleIdList></Reference><Reference><Citation>J Med Virol. 2006 Jan;78(1):1-8</Citation><ArticleIdList><ArticleId IdType="pubmed">16299724</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2002 May;76(10):4792-7</Citation><ArticleIdList><ArticleId IdType="pubmed">11967296</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Microbiol. 2006 Feb;44(2):359-65</Citation><ArticleIdList><ArticleId IdType="pubmed">16455884</ArticleId></ArticleIdList></Reference><Reference><Citation>Virus Res. 2008 Apr;133(1):113-21</Citation><ArticleIdList><ArticleId IdType="pubmed">18045721</ArticleId></ArticleIdList></Reference><Reference><Citation>Microbiol Mol Biol Rev. 2005 Dec;69(4):635-64</Citation><ArticleIdList><ArticleId IdType="pubmed">16339739</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2009 Jun 12;27(29):3912-20</Citation><ArticleIdList><ArticleId IdType="pubmed">19490987</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2011 Sep 2;29(38):6670-8</Citation><ArticleIdList><ArticleId IdType="pubmed">21745520</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2004 Dec 9;432(7018):769-75</Citation><ArticleIdList><ArticleId IdType="pubmed">15592417</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 2005 Jan 5;331(1):128-35</Citation><ArticleIdList><ArticleId IdType="pubmed">15582659</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Singapour</li></country></list><tree><country name="Singapour"><noRegion><name sortKey="Janice Oh, Hsueh Ling" sort="Janice Oh, Hsueh Ling" uniqKey="Janice Oh H" first="Hsueh-Ling" last="Janice Oh">Hsueh-Ling Janice Oh</name></noRegion><name sortKey="Bertoletti, Antonio" sort="Bertoletti, Antonio" uniqKey="Bertoletti A" first="Antonio" last="Bertoletti">Antonio Bertoletti</name><name sortKey="Ken En Gan, Samuel" sort="Ken En Gan, Samuel" uniqKey="Ken En Gan S" first="Samuel" last="Ken-En Gan">Samuel Ken-En Gan</name><name sortKey="Tan, Yee Joo" sort="Tan, Yee Joo" uniqKey="Tan Y" first="Yee-Joo" last="Tan">Yee-Joo Tan</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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