Medically unexplained symptoms in the times of Covid-19 pandemic: a case-report
Identifieur interne : 000836 ( Pmc/Curation ); précédent : 000835; suivant : 000837Medically unexplained symptoms in the times of Covid-19 pandemic: a case-report
Auteurs : Marco Colizzi [Italie, Royaume-Uni] ; Riccardo Bortoletto ; Marta Silvestri ; Federica Mondini ; Elena Puttini ; Chiara Cainelli ; Rossella Gaudino [Italie] ; Mirella Ruggeri [Italie] ; Leonardo ZoccanteSource :
- Brain, Behavior, & Immunity Health [ 2666-3546 ] ; 2020.
Abstract
In early 2020, a novel coronavirus (SARS-CoV-2) leading to a potentially fatal condition was discovered. Since then, the 2019 coronavirus disease (COVID-19) has spread worldwide becoming a pandemic. Beyond the risks strictly related to the infection, concerns have been expressed for the psychological impact that COVID-19 may have, especially on vulnerable individuals with pre-existing mental health conditions. Somatic symptom disorder (SSD) is characterized by a dysfunctional preoccupation with physical symptoms leading to excessive and unnecessary healthcare utilization. Despite being quite common, such condition remains underrecognized. We report a detailed clinical case of a 16 years old adolescent, who presented with a history suggestive of COVID-19 infection and associated psychological distress. Despite testing negative for the presence of SARS-CoV-2, his extreme and persisting health preoccupations required an inpatient admission to the Child and Adolescent Neuropsychiatric Unit. He responded rapidly to a low dose of antipsychotic and an antidepressant. Based on his medical history and current presentation, he received a diagnosis of SSD. When COVID-19-like symptoms occur, we highlight the importance of differentially diagnosing a possible exacerbation of a pre-existing SSD, triggered by fear of being infected. This may help preventing further burden to the healthcare system.
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DOI: 10.1016/j.bbih.2020.100073
PubMed: NONE
PubMed Central: 7166302
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Marco Colizzi<affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation>Le document en format XML
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case-report</title><author><name sortKey="Colizzi, Marco" sort="Colizzi, Marco" uniqKey="Colizzi M" first="Marco" last="Colizzi">Marco Colizzi</name><affiliation wicri:level="1"><nlm:aff id="aff1">Section of Psychiatry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Psychiatry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">National Institute for Health Research (NIHR) Biomedical Research Centre (BRC), South London and Maudsley NHS Foundation Trust, and Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Institute for Health Research (NIHR) Biomedical Research Centre (BRC), South London and Maudsley NHS Foundation Trust, and Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London</wicri:regionArea></affiliation><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation></author><author><name sortKey="Bortoletto, Riccardo" sort="Bortoletto, Riccardo" uniqKey="Bortoletto R" first="Riccardo" last="Bortoletto">Riccardo Bortoletto</name><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation></author><author><name sortKey="Silvestri, Marta" sort="Silvestri, Marta" uniqKey="Silvestri M" first="Marta" last="Silvestri">Marta Silvestri</name><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation></author><author><name sortKey="Mondini, Federica" sort="Mondini, Federica" uniqKey="Mondini F" first="Federica" last="Mondini">Federica Mondini</name><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation></author><author><name sortKey="Puttini, Elena" sort="Puttini, Elena" uniqKey="Puttini E" first="Elena" last="Puttini">Elena Puttini</name><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation></author><author><name sortKey="Cainelli, Chiara" sort="Cainelli, Chiara" uniqKey="Cainelli C" first="Chiara" last="Cainelli">Chiara Cainelli</name><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation></author><author><name sortKey="Gaudino, Rossella" sort="Gaudino, Rossella" uniqKey="Gaudino R" first="Rossella" last="Gaudino">Rossella Gaudino</name><affiliation wicri:level="1"><nlm:aff id="aff4">Section of Paediatrics, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University of Verona, Verona, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Paediatrics, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University of Verona, Verona</wicri:regionArea></affiliation></author><author><name sortKey="Ruggeri, Mirella" sort="Ruggeri, Mirella" uniqKey="Ruggeri M" first="Mirella" last="Ruggeri">Mirella Ruggeri</name><affiliation wicri:level="1"><nlm:aff id="aff1">Section of Psychiatry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Psychiatry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona</wicri:regionArea></affiliation></author><author><name sortKey="Zoccante, Leonardo" sort="Zoccante, Leonardo" uniqKey="Zoccante L" first="Leonardo" last="Zoccante">Leonardo Zoccante</name><affiliation><nlm:aff id="aff3">Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</nlm:aff><wicri:noCountry code="subfield">Integrated University Hospital of Verona</wicri:noCountry></affiliation></author></analytic><series><title level="j">Brain, Behavior, & Immunity Health</title><idno type="eISSN">2666-3546</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In early 2020, a novel coronavirus (SARS-CoV-2) leading to a potentially fatal condition was discovered. Since then, the 2019 coronavirus disease (COVID-19) has spread worldwide becoming a pandemic. Beyond the risks strictly related to the infection, concerns have been expressed for the psychological impact that COVID-19 may have, especially on vulnerable individuals with pre-existing mental health conditions. Somatic symptom disorder (SSD) is characterized by a dysfunctional preoccupation with physical symptoms leading to excessive and unnecessary healthcare utilization. Despite being quite common, such condition remains underrecognized. We report a detailed clinical case of a 16 years old adolescent, who presented with a history suggestive of COVID-19 infection and associated psychological distress. Despite testing negative for the presence of SARS-CoV-2, his extreme and persisting health preoccupations required an inpatient admission to the Child and Adolescent Neuropsychiatric Unit. He responded rapidly to a low dose of antipsychotic and an antidepressant. Based on his medical history and current presentation, he received a diagnosis of SSD. When COVID-19-like symptoms occur, we highlight the importance of differentially diagnosing a possible exacerbation of a pre-existing SSD, triggered by fear of being infected. This may help preventing further burden to the healthcare system.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Baranowska, B" uniqKey="Baranowska B">B. Baranowska</name></author><author><name sortKey="Kochanowski, J" uniqKey="Kochanowski J">J. Kochanowski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barsky, A J" uniqKey="Barsky A">A.J. Barsky</name></author><author><name sortKey="Orav, E J" uniqKey="Orav E">E.J. Orav</name></author><author><name sortKey="Bates, D W" uniqKey="Bates D">D.W. Bates</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bedard Thomas, K K" uniqKey="Bedard Thomas K">K.K. Bedard-Thomas</name></author><author><name sortKey="Bujoreanu, S" uniqKey="Bujoreanu S">S. Bujoreanu</name></author><author><name sortKey="Choi, C H" uniqKey="Choi C">C.H. Choi</name></author><author><name sortKey="Ibeziako, P I" uniqKey="Ibeziako P">P.I. Ibeziako</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Berger, Z D" uniqKey="Berger Z">Z.D. Berger</name></author><author><name sortKey="Evans, N G" uniqKey="Evans N">N.G. Evans</name></author><author><name sortKey="Phelan, A L" uniqKey="Phelan A">A.L. Phelan</name></author><author><name sortKey="Silverman, R D" uniqKey="Silverman R">R.D. Silverman</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Colizzi, M" uniqKey="Colizzi M">M. Colizzi</name></author><author><name sortKey="Lasalvia, A" uniqKey="Lasalvia A">A. Lasalvia</name></author><author><name sortKey="Ruggeri, M" uniqKey="Ruggeri M">M. Ruggeri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cucinotta, D" uniqKey="Cucinotta D">D. Cucinotta</name></author><author><name sortKey="Vanelli, M" uniqKey="Vanelli M">M. Vanelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dong, Y" uniqKey="Dong Y">Y. Dong</name></author><author><name sortKey="Mo, X" uniqKey="Mo X">X. Mo</name></author><author><name sortKey="Hu, Y" uniqKey="Hu Y">Y. Hu</name></author><author><name sortKey="Qi, X" uniqKey="Qi X">X. Qi</name></author><author><name sortKey="Jiang, F" uniqKey="Jiang F">F. Jiang</name></author><author><name sortKey="Jiang, Z" uniqKey="Jiang Z">Z. Jiang</name></author><author><name sortKey="Tong, S" uniqKey="Tong S">S. Tong</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Gagliano, A" uniqKey="Gagliano A">A. Gagliano</name></author><author><name sortKey="Villani, P G" uniqKey="Villani P">P.G. Villani</name></author><author><name sortKey="C, F M" uniqKey="C F">F.M. Cò</name></author><author><name sortKey="Paglia, S" uniqKey="Paglia S">S. Paglia</name></author><author><name sortKey="Bisagni, P A G" uniqKey="Bisagni P">P.A.G. Bisagni</name></author><author><name sortKey="Perotti, G M" uniqKey="Perotti G">G.M. Perotti</name></author><author><name sortKey="Storti, E" uniqKey="Storti E">E. Storti</name></author><author><name sortKey="Lombardo, M" uniqKey="Lombardo M">M. Lombardo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garfin, D R" uniqKey="Garfin D">D.R. Garfin</name></author><author><name sortKey="Silver, R C" uniqKey="Silver R">R.C. Silver</name></author><author><name sortKey="Holman, E A" uniqKey="Holman E">E.A. Holman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author><author><name sortKey="Ren, L" uniqKey="Ren L">L. Ren</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Hu, Y" uniqKey="Hu Y">Y. Hu</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author><author><name sortKey="Fan, G" uniqKey="Fan G">G. Fan</name></author><author><name sortKey="Xu, J" uniqKey="Xu J">J. Xu</name></author><author><name sortKey="Gu, X" uniqKey="Gu X">X. Gu</name></author><author><name sortKey="Cheng, Z" uniqKey="Cheng Z">Z. Cheng</name></author><author><name sortKey="Yu, T" uniqKey="Yu T">T. Yu</name></author><author><name sortKey="Xia, J" uniqKey="Xia J">J. Xia</name></author><author><name sortKey="Wei, Y" uniqKey="Wei Y">Y. Wei</name></author><author><name sortKey="Wu, W" uniqKey="Wu W">W. Wu</name></author><author><name sortKey="Xie, X" uniqKey="Xie X">X. Xie</name></author><author><name sortKey="Yin, W" uniqKey="Yin W">W. Yin</name></author><author><name sortKey="Li, H" uniqKey="Li H">H. Li</name></author><author><name sortKey="Liu, M" uniqKey="Liu M">M. Liu</name></author><author><name sortKey="Xiao, Y" uniqKey="Xiao Y">Y. Xiao</name></author><author><name sortKey="Gao, H" uniqKey="Gao H">H. Gao</name></author><author><name sortKey="Guo, L" uniqKey="Guo L">L. Guo</name></author><author><name sortKey="Xie, J" uniqKey="Xie J">J. Xie</name></author><author><name sortKey="Wang, G" uniqKey="Wang G">G. Wang</name></author><author><name sortKey="Jiang, R" uniqKey="Jiang R">R. Jiang</name></author><author><name sortKey="Gao, Z" uniqKey="Gao Z">Z. Gao</name></author><author><name sortKey="Jin, Q" uniqKey="Jin Q">Q. Jin</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J. Wang</name></author><author><name sortKey="Cao, B" uniqKey="Cao B">B. Cao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lai, J" uniqKey="Lai J">J. Lai</name></author><author><name sortKey="Ma, S" uniqKey="Ma S">S. Ma</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Cai, Z" uniqKey="Cai Z">Z. Cai</name></author><author><name sortKey="Hu, J" uniqKey="Hu J">J. Hu</name></author><author><name sortKey="Wei, N" uniqKey="Wei N">N. Wei</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J. Wu</name></author><author><name sortKey="Du, H" uniqKey="Du H">H. Du</name></author><author><name sortKey="Chen, T" uniqKey="Chen T">T. Chen</name></author><author><name sortKey="Li, R" uniqKey="Li R">R. Li</name></author><author><name sortKey="Tan, H" uniqKey="Tan H">H. Tan</name></author><author><name sortKey="Kang, L" uniqKey="Kang L">L. Kang</name></author><author><name sortKey="Yao, L" uniqKey="Yao L">L. Yao</name></author><author><name sortKey="Huang, M" uniqKey="Huang M">M. Huang</name></author><author><name sortKey="Wang, H" uniqKey="Wang H">H. Wang</name></author><author><name sortKey="Wang, G" uniqKey="Wang G">G. Wang</name></author><author><name sortKey="Liu, Z" uniqKey="Liu Z">Z. Liu</name></author><author><name sortKey="Hu, S" uniqKey="Hu S">S. Hu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, J" uniqKey="Li J">J. Li</name></author><author><name sortKey="Zhang, M M" uniqKey="Zhang M">M.M. Zhang</name></author><author><name sortKey="Zhao, L" uniqKey="Zhao L">L. Zhao</name></author><author><name sortKey="Li, W Q" uniqKey="Li W">W.Q. Li</name></author><author><name sortKey="Mu, J L" uniqKey="Mu J">J.L. Mu</name></author><author><name sortKey="Zhang, Z H" uniqKey="Zhang Z">Z.H. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Q" uniqKey="Li Q">Q. Li</name></author><author><name sortKey="Guan, X" uniqKey="Guan X">X. Guan</name></author><author><name sortKey="Wu, P" uniqKey="Wu P">P. Wu</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Zhou, L" uniqKey="Zhou L">L. Zhou</name></author><author><name sortKey="Tong, Y" uniqKey="Tong Y">Y. Tong</name></author><author><name sortKey="Ren, R" uniqKey="Ren R">R. Ren</name></author><author><name sortKey="Leung, K S M" uniqKey="Leung K">K.S.M. Leung</name></author><author><name sortKey="Lau, E H Y" uniqKey="Lau E">E.H.Y. Lau</name></author><author><name sortKey="Wong, J Y" uniqKey="Wong J">J.Y. Wong</name></author><author><name sortKey="Xing, X" uniqKey="Xing X">X. Xing</name></author><author><name sortKey="Xiang, N" uniqKey="Xiang N">N. Xiang</name></author><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y. Wu</name></author><author><name sortKey="Li, C" uniqKey="Li C">C. Li</name></author><author><name sortKey="Chen, Q" uniqKey="Chen Q">Q. Chen</name></author><author><name sortKey="Li, D" uniqKey="Li D">D. Li</name></author><author><name sortKey="Liu, T" uniqKey="Liu T">T. Liu</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Liu, M" uniqKey="Liu M">M. Liu</name></author><author><name sortKey="Tu, W" uniqKey="Tu W">W. Tu</name></author><author><name sortKey="Chen, C" uniqKey="Chen C">C. Chen</name></author><author><name sortKey="Jin, L" uniqKey="Jin L">L. Jin</name></author><author><name sortKey="Yang, R" uniqKey="Yang R">R. Yang</name></author><author><name sortKey="Wang, Q" uniqKey="Wang Q">Q. Wang</name></author><author><name sortKey="Zhou, S" uniqKey="Zhou S">S. Zhou</name></author><author><name sortKey="Wang, R" uniqKey="Wang R">R. Wang</name></author><author><name sortKey="Liu, H" uniqKey="Liu H">H. Liu</name></author><author><name sortKey="Luo, Y" uniqKey="Luo Y">Y. Luo</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y. Liu</name></author><author><name sortKey="Shao, G" uniqKey="Shao G">G. Shao</name></author><author><name sortKey="Li, H" uniqKey="Li H">H. Li</name></author><author><name sortKey="Tao, Z" uniqKey="Tao Z">Z. Tao</name></author><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y. Yang</name></author><author><name sortKey="Deng, Z" uniqKey="Deng Z">Z. Deng</name></author><author><name sortKey="Liu, B" uniqKey="Liu B">B. Liu</name></author><author><name sortKey="Ma, Z" uniqKey="Ma Z">Z. Ma</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y. Zhang</name></author><author><name sortKey="Shi, G" uniqKey="Shi G">G. Shi</name></author><author><name sortKey="Lam, T T Y" uniqKey="Lam T">T.T.Y. Lam</name></author><author><name sortKey="Wu, J T" uniqKey="Wu J">J.T. Wu</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G.F. Gao</name></author><author><name sortKey="Cowling, B J" uniqKey="Cowling B">B.J. Cowling</name></author><author><name sortKey="Yang, B" uniqKey="Yang B">B. Yang</name></author><author><name sortKey="Leung, G M" uniqKey="Leung G">G.M. Leung</name></author><author><name sortKey="Feng, Z" uniqKey="Feng Z">Z. Feng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lima, C K T" uniqKey="Lima C">C.K.T. Lima</name></author><author><name sortKey="Carvalho, P M M" uniqKey="Carvalho P">P.M.M. Carvalho</name></author><author><name sortKey="Lima, I A A S" uniqKey="Lima I">I.A.A.S. Lima</name></author><author><name sortKey="Nunes, J V A O" uniqKey="Nunes J">J.V.A.O. Nunes</name></author><author><name sortKey="Saraiva, J S" uniqKey="Saraiva J">J.S. Saraiva</name></author><author><name sortKey="De Souza, R I" uniqKey="De Souza R">R.I. de Souza</name></author><author><name sortKey="Da Silva, C G L" uniqKey="Da Silva C">C.G.L. da Silva</name></author><author><name sortKey="Neto, M L R" uniqKey="Neto M">M.L.R. Neto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, R" uniqKey="Lu R">R. Lu</name></author><author><name sortKey="Zhao, X" uniqKey="Zhao X">X. Zhao</name></author><author><name sortKey="Li, J" uniqKey="Li J">J. Li</name></author><author><name sortKey="Niu, P" uniqKey="Niu P">P. Niu</name></author><author><name sortKey="Yang, B" uniqKey="Yang B">B. Yang</name></author><author><name sortKey="Wu, H" uniqKey="Wu H">H. Wu</name></author><author><name sortKey="Wang, W" uniqKey="Wang W">W. Wang</name></author><author><name sortKey="Song, H" uniqKey="Song H">H. Song</name></author><author><name sortKey="Huang, B" uniqKey="Huang B">B. Huang</name></author><author><name sortKey="Zhu, N" uniqKey="Zhu N">N. Zhu</name></author><author><name sortKey="Bi, Y" uniqKey="Bi Y">Y. Bi</name></author><author><name sortKey="Ma, X" uniqKey="Ma X">X. Ma</name></author><author><name sortKey="Zhan, F" uniqKey="Zhan F">F. Zhan</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L. Wang</name></author><author><name sortKey="Hu, T" uniqKey="Hu T">T. Hu</name></author><author><name sortKey="Zhou, H" uniqKey="Zhou H">H. Zhou</name></author><author><name sortKey="Hu, Z" uniqKey="Hu Z">Z. Hu</name></author><author><name sortKey="Zhou, W" uniqKey="Zhou W">W. Zhou</name></author><author><name sortKey="Zhao, L" uniqKey="Zhao L">L. Zhao</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J. Chen</name></author><author><name sortKey="Meng, Y" uniqKey="Meng Y">Y. Meng</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J. Wang</name></author><author><name sortKey="Lin, Y" uniqKey="Lin Y">Y. Lin</name></author><author><name sortKey="Yuan, J" uniqKey="Yuan J">J. Yuan</name></author><author><name sortKey="Xie, Z" uniqKey="Xie Z">Z. Xie</name></author><author><name sortKey="Ma, J" uniqKey="Ma J">J. Ma</name></author><author><name sortKey="Liu, W J" uniqKey="Liu W">W.J. Liu</name></author><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Xu, W" uniqKey="Xu W">W. Xu</name></author><author><name sortKey="Holmes, E C" uniqKey="Holmes E">E.C. Holmes</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G.F. Gao</name></author><author><name sortKey="Wu, G" uniqKey="Wu G">G. Wu</name></author><author><name sortKey="Chen, W" uniqKey="Chen W">W. Chen</name></author><author><name sortKey="Shi, W" uniqKey="Shi W">W. Shi</name></author><author><name sortKey="Tan, W" uniqKey="Tan W">W. Tan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Onder, G" uniqKey="Onder G">G. Onder</name></author><author><name sortKey="Rezza, G" uniqKey="Rezza G">G. Rezza</name></author><author><name sortKey="Brusaferro, S" uniqKey="Brusaferro S">S. Brusaferro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosic, T" uniqKey="Rosic T">T. Rosic</name></author><author><name sortKey="Kalra, S" uniqKey="Kalra S">S. Kalra</name></author><author><name sortKey="Samaan, Z" uniqKey="Samaan Z">Z. Samaan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rothe, C" uniqKey="Rothe C">C. Rothe</name></author><author><name sortKey="Schunk, M" uniqKey="Schunk M">M. Schunk</name></author><author><name sortKey="Sothmann, P" uniqKey="Sothmann P">P. Sothmann</name></author><author><name sortKey="Bretzel, G" uniqKey="Bretzel G">G. Bretzel</name></author><author><name sortKey="Froeschl, G" uniqKey="Froeschl G">G. Froeschl</name></author><author><name sortKey="Wallrauch, C" uniqKey="Wallrauch C">C. Wallrauch</name></author><author><name sortKey="Zimmer, T" uniqKey="Zimmer T">T. Zimmer</name></author><author><name sortKey="Thiel, V" uniqKey="Thiel V">V. Thiel</name></author><author><name sortKey="Janke, C" uniqKey="Janke C">C. Janke</name></author><author><name sortKey="Guggemos, W" uniqKey="Guggemos W">W. Guggemos</name></author><author><name sortKey="Seilmaier, M" uniqKey="Seilmaier M">M. Seilmaier</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Vollmar, P" uniqKey="Vollmar P">P. Vollmar</name></author><author><name sortKey="Zwirglmaier, K" uniqKey="Zwirglmaier K">K. Zwirglmaier</name></author><author><name sortKey="Zange, S" uniqKey="Zange S">S. Zange</name></author><author><name sortKey="Wolfel, R" uniqKey="Wolfel R">R. Wölfel</name></author><author><name sortKey="Hoelscher, M" uniqKey="Hoelscher M">M. Hoelscher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sartorious, N" uniqKey="Sartorious N">N. Sartorious</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seminog, O O" uniqKey="Seminog O">O.O. Seminog</name></author><author><name sortKey="Goldacre, M J" uniqKey="Goldacre M">M.J. Goldacre</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Wilder Smith, A" uniqKey="Wilder Smith A">A. Wilder-Smith</name></author><author><name sortKey="Freedman, D O" uniqKey="Freedman D">D.O. Freedman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yao, H" uniqKey="Yao H">H. Yao</name></author><author><name sortKey="Chen, J H" uniqKey="Chen J">J.H. Chen</name></author><author><name sortKey="Xu, Y F" uniqKey="Xu Y">Y.F. Xu</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="brief-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Brain Behav Immun Health</journal-id><journal-id journal-id-type="iso-abbrev">Brain Behav Immun Health</journal-id><journal-title-group><journal-title>Brain, Behavior, & Immunity Health</journal-title></journal-title-group><issn pub-type="epub">2666-3546</issn><publisher><publisher-name>The Author(s). Published by Elsevier Inc.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmc">7166302</article-id><article-id pub-id-type="publisher-id">S2666-3546(20)30038-7</article-id><article-id pub-id-type="doi">10.1016/j.bbih.2020.100073</article-id><article-id pub-id-type="publisher-id">100073</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Medically unexplained symptoms in the times of Covid-19 pandemic: a case-report</article-title></title-group><contrib-group><contrib contrib-type="author" id="au1"><name><surname>Colizzi</surname><given-names>Marco</given-names></name><degrees>M.D., Ph.D.</degrees><email>marco.colizzi@univr.it</email><xref rid="aff1" ref-type="aff">1</xref><xref rid="aff2" ref-type="aff">2</xref><xref rid="aff3" ref-type="aff">3</xref><xref rid="cor1" ref-type="corresp">∗</xref></contrib><contrib contrib-type="author" id="au2"><name><surname>Bortoletto</surname><given-names>Riccardo</given-names></name><degrees>M.D.</degrees><xref rid="aff3" ref-type="aff">3</xref></contrib><contrib contrib-type="author" id="au3"><name><surname>Silvestri</surname><given-names>Marta</given-names></name><degrees>M.D.</degrees><xref rid="aff3" ref-type="aff">3</xref></contrib><contrib contrib-type="author" id="au4"><name><surname>Mondini</surname><given-names>Federica</given-names></name><degrees>M.D.</degrees><xref rid="aff3" ref-type="aff">3</xref></contrib><contrib contrib-type="author" id="au5"><name><surname>Puttini</surname><given-names>Elena</given-names></name><degrees>Psy.D.</degrees><xref rid="aff3" ref-type="aff">3</xref></contrib><contrib contrib-type="author" id="au6"><name><surname>Cainelli</surname><given-names>Chiara</given-names></name><degrees>Psy.D.</degrees><xref rid="aff3" ref-type="aff">3</xref></contrib><contrib contrib-type="author" id="au7"><name><surname>Gaudino</surname><given-names>Rossella</given-names></name><degrees>M.D.</degrees><xref rid="aff4" ref-type="aff">4</xref></contrib><contrib contrib-type="author" id="au8"><name><surname>Ruggeri</surname><given-names>Mirella</given-names></name><degrees>M.D., Ph.D.</degrees><xref rid="aff1" ref-type="aff">1</xref></contrib><contrib contrib-type="author" id="au9"><name><surname>Zoccante</surname><given-names>Leonardo</given-names></name><degrees>M.D.</degrees><xref rid="aff3" ref-type="aff">3</xref></contrib></contrib-group><aff id="aff1"><label>1</label>Section of Psychiatry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy</aff><aff id="aff2"><label>2</label>National Institute for Health Research (NIHR) Biomedical Research Centre (BRC), South London and Maudsley NHS Foundation Trust, and Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, United Kingdom</aff><aff id="aff3"><label>3</label>Child and Adolescent Neuropsychiatry Unit, Maternal-Child Integrated Care Department, Integrated University Hospital of Verona</aff><aff id="aff4"><label>4</label>Section of Paediatrics, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University of Verona, Verona, Italy</aff><author-notes><corresp id="cor1"><label>∗</label>Correspondiing author. Section of Psychiatry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy. Telephone number: +39 045 812 6832. <email>marco.colizzi@univr.it</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>19</day><month>4</month><year>2020</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="epub"><day>19</day><month>4</month><year>2020</year></pub-date><elocation-id>100073</elocation-id><history><date date-type="received"><day>9</day><month>4</month><year>2020</year></date><date date-type="accepted"><day>17</day><month>4</month><year>2020</year></date></history><permissions><copyright-statement>© 2020 The Author(s)</copyright-statement><copyright-year>2020</copyright-year><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract id="abs0010"><p>In early 2020, a novel coronavirus (SARS-CoV-2) leading to a potentially fatal condition was discovered. Since then, the 2019 coronavirus disease (COVID-19) has spread worldwide becoming a pandemic. Beyond the risks strictly related to the infection, concerns have been expressed for the psychological impact that COVID-19 may have, especially on vulnerable individuals with pre-existing mental health conditions. Somatic symptom disorder (SSD) is characterized by a dysfunctional preoccupation with physical symptoms leading to excessive and unnecessary healthcare utilization. Despite being quite common, such condition remains underrecognized. We report a detailed clinical case of a 16 years old adolescent, who presented with a history suggestive of COVID-19 infection and associated psychological distress. Despite testing negative for the presence of SARS-CoV-2, his extreme and persisting health preoccupations required an inpatient admission to the Child and Adolescent Neuropsychiatric Unit. He responded rapidly to a low dose of antipsychotic and an antidepressant. Based on his medical history and current presentation, he received a diagnosis of SSD. When COVID-19-like symptoms occur, we highlight the importance of differentially diagnosing a possible exacerbation of a pre-existing SSD, triggered by fear of being infected. This may help preventing further burden to the healthcare system.</p></abstract><abstract abstract-type="author-highlights" id="abs0015"><title>Highlights</title><p><list list-type="simple" id="ulist0010"><list-item id="u0010"><label>•</label><p id="p0010">COVID-19 may have a substantial psychological impact, independent of getting the infection</p></list-item><list-item id="u0015"><label>•</label><p id="p0015">Fear to get COVID-19 may exacerbate pre-existing mental health disorders</p></list-item><list-item id="u0020"><label>•</label><p id="p0020">Extreme anxiety reactions to COVID-19 may elicit unexplained medical symptoms in predisposed individuals</p></list-item></list></p></abstract><kwd-group id="kwrds0010"><title>Keywords</title><kwd>Coronavirus</kwd><kwd>2019-nCoV</kwd><kwd>Somatic Symptom Disorder</kwd><kwd>Anxiety</kwd><kwd>Obsessive Compulsive Symptoms</kwd><kwd>Child and Adolescent Psychiatry</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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