Longitudinal Analysis of Severe Acute Respiratory Syndrome (SARS) Coronavirus-Specific Antibody in SARS Patients
Identifieur interne : 000630 ( Pmc/Curation ); précédent : 000629; suivant : 000631Longitudinal Analysis of Severe Acute Respiratory Syndrome (SARS) Coronavirus-Specific Antibody in SARS Patients
Auteurs : Shan-Chwen Chang ; Jann-Tay Wang ; Li-Min Huang ; Yee-Chun Chen ; Chi-Tai Fang ; Wang-Huei Sheng ; Jiun-Ling Wang ; Chong-Jen Yu ; Pan-Chyr YangSource :
- Clinical and Diagnostic Laboratory Immunology [ 1071-412X ] ; 2005.
Abstract
The serum antibodies to severe acute respiratory syndrome (SARS) coronavirus of 18 SARS patients were checked at 1 month and every 3 months after disease onset. All of them except one, who missed blood sampling at 1 month, tested positive for the immunoglobulin G (IgG) antibody at 1 month. Fifteen out of 17 tested positive for the IgM antibody at 1 month. The serum IgM antibody of most patients became undetectable within 6 months after the onset of SARS. The IgG antibody of all 17 patients, whose serum was checked 1 year after disease onset, remained positive.
Url:
DOI: 10.1128/CDLI.12.12.1455-1457.2005
PubMed: 16339072
PubMed Central: 1317065
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<front><div type="abstract" xml:lang="en"><p>The serum antibodies to severe acute respiratory syndrome (SARS) coronavirus of 18 SARS patients were checked at 1 month and every 3 months after disease onset. All of them except one, who missed blood sampling at 1 month, tested positive for the immunoglobulin G (IgG) antibody at 1 month. Fifteen out of 17 tested positive for the IgM antibody at 1 month. The serum IgM antibody of most patients became undetectable within 6 months after the onset of SARS. The IgG antibody of all 17 patients, whose serum was checked 1 year after disease onset, remained positive.</p>
</div>
</front>
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<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Diagn Lab Immunol</journal-id>
<journal-id journal-id-type="publisher-id">cdli</journal-id>
<journal-title>Clinical and Diagnostic Laboratory Immunology</journal-title>
<issn pub-type="ppub">1071-412X</issn>
<issn pub-type="epub">1098-6588</issn>
<publisher><publisher-name>American Society for Microbiology</publisher-name>
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<article-meta><article-id pub-id-type="pmid">16339072</article-id>
<article-id pub-id-type="pmc">1317065</article-id>
<article-id pub-id-type="publisher-id">0045-05</article-id>
<article-id pub-id-type="doi">10.1128/CDLI.12.12.1455-1457.2005</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Microbial Immunology</subject>
</subj-group>
</article-categories>
<title-group><article-title>Longitudinal Analysis of Severe Acute Respiratory Syndrome (SARS) Coronavirus-Specific Antibody in SARS Patients</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Chang</surname>
<given-names>Shan-Chwen</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="corresp" rid="cor1">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wang</surname>
<given-names>Jann-Tay</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Huang</surname>
<given-names>Li-Min</given-names>
</name>
<xref ref-type="aff" rid="aff1">2</xref>
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<contrib contrib-type="author"><name><surname>Chen</surname>
<given-names>Yee-Chun</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
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<contrib contrib-type="author"><name><surname>Fang</surname>
<given-names>Chi-Tai</given-names>
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<xref ref-type="aff" rid="aff1">1</xref>
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<contrib contrib-type="author"><name><surname>Sheng</surname>
<given-names>Wang-Huei</given-names>
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<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wang</surname>
<given-names>Jiun-Ling</given-names>
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<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yu</surname>
<given-names>Chong-Jen</given-names>
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<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yang</surname>
<given-names>Pan-Chyr</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
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<aff id="aff1">Department of Internal Medicine,<label>1</label>
Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan<label>2</label>
</aff>
<author-notes><fn id="cor1"><label>*</label>
<p>Corresponding author. Mailing address: Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan. Phone: 886-2-23123456, ext. 5401. Fax: 886-2-23971412. E-mail: <email>sc4030@ha.mc.ntu.edu.tw</email>
.</p>
</fn>
</author-notes>
<pub-date pub-type="ppub"><month>12</month>
<year>2005</year>
</pub-date>
<volume>12</volume>
<issue>12</issue>
<fpage>1455</fpage>
<lpage>1457</lpage>
<history><date date-type="received"><day>14</day>
<month>2</month>
<year>2005</year>
</date>
<date date-type="rev-recd"><day>12</day>
<month>4</month>
<year>2005</year>
</date>
<date date-type="accepted"><day>29</day>
<month>9</month>
<year>2005</year>
</date>
</history>
<copyright-statement>Copyright © 2005, American Society for Microbiology</copyright-statement>
<copyright-year>2005</copyright-year>
<abstract><p>The serum antibodies to severe acute respiratory syndrome (SARS) coronavirus of 18 SARS patients were checked at 1 month and every 3 months after disease onset. All of them except one, who missed blood sampling at 1 month, tested positive for the immunoglobulin G (IgG) antibody at 1 month. Fifteen out of 17 tested positive for the IgM antibody at 1 month. The serum IgM antibody of most patients became undetectable within 6 months after the onset of SARS. The IgG antibody of all 17 patients, whose serum was checked 1 year after disease onset, remained positive.</p>
</abstract>
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