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Longitudinal Analysis of Severe Acute Respiratory Syndrome (SARS) Coronavirus-Specific Antibody in SARS Patients

Identifieur interne : 000630 ( Pmc/Corpus ); précédent : 000629; suivant : 000631

Longitudinal Analysis of Severe Acute Respiratory Syndrome (SARS) Coronavirus-Specific Antibody in SARS Patients

Auteurs : Shan-Chwen Chang ; Jann-Tay Wang ; Li-Min Huang ; Yee-Chun Chen ; Chi-Tai Fang ; Wang-Huei Sheng ; Jiun-Ling Wang ; Chong-Jen Yu ; Pan-Chyr Yang

Source :

RBID : PMC:1317065

Abstract

The serum antibodies to severe acute respiratory syndrome (SARS) coronavirus of 18 SARS patients were checked at 1 month and every 3 months after disease onset. All of them except one, who missed blood sampling at 1 month, tested positive for the immunoglobulin G (IgG) antibody at 1 month. Fifteen out of 17 tested positive for the IgM antibody at 1 month. The serum IgM antibody of most patients became undetectable within 6 months after the onset of SARS. The IgG antibody of all 17 patients, whose serum was checked 1 year after disease onset, remained positive.


Url:
DOI: 10.1128/CDLI.12.12.1455-1457.2005
PubMed: 16339072
PubMed Central: 1317065

Links to Exploration step

PMC:1317065

Le document en format XML

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<name sortKey="Yu, Chong Jen" sort="Yu, Chong Jen" uniqKey="Yu C" first="Chong-Jen" last="Yu">Chong-Jen Yu</name>
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<name sortKey="Yang, Pan Chyr" sort="Yang, Pan Chyr" uniqKey="Yang P" first="Pan-Chyr" last="Yang">Pan-Chyr Yang</name>
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<name sortKey="Wang, Jiun Ling" sort="Wang, Jiun Ling" uniqKey="Wang J" first="Jiun-Ling" last="Wang">Jiun-Ling Wang</name>
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<name sortKey="Yu, Chong Jen" sort="Yu, Chong Jen" uniqKey="Yu C" first="Chong-Jen" last="Yu">Chong-Jen Yu</name>
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<title level="j">Clinical and Diagnostic Laboratory Immunology</title>
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<p>The serum antibodies to severe acute respiratory syndrome (SARS) coronavirus of 18 SARS patients were checked at 1 month and every 3 months after disease onset. All of them except one, who missed blood sampling at 1 month, tested positive for the immunoglobulin G (IgG) antibody at 1 month. Fifteen out of 17 tested positive for the IgM antibody at 1 month. The serum IgM antibody of most patients became undetectable within 6 months after the onset of SARS. The IgG antibody of all 17 patients, whose serum was checked 1 year after disease onset, remained positive.</p>
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<journal-id journal-id-type="nlm-ta">Clin Diagn Lab Immunol</journal-id>
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<journal-title>Clinical and Diagnostic Laboratory Immunology</journal-title>
<issn pub-type="ppub">1071-412X</issn>
<issn pub-type="epub">1098-6588</issn>
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<publisher-name>American Society for Microbiology</publisher-name>
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<article-id pub-id-type="pmc">1317065</article-id>
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<article-id pub-id-type="doi">10.1128/CDLI.12.12.1455-1457.2005</article-id>
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<subject>Microbial Immunology</subject>
</subj-group>
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<title-group>
<article-title>Longitudinal Analysis of Severe Acute Respiratory Syndrome (SARS) Coronavirus-Specific Antibody in SARS Patients</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Chang</surname>
<given-names>Shan-Chwen</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="corresp" rid="cor1">*</xref>
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<surname>Wang</surname>
<given-names>Jann-Tay</given-names>
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<name>
<surname>Huang</surname>
<given-names>Li-Min</given-names>
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<xref ref-type="aff" rid="aff1">2</xref>
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<contrib contrib-type="author">
<name>
<surname>Chen</surname>
<given-names>Yee-Chun</given-names>
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<name>
<surname>Wang</surname>
<given-names>Jiun-Ling</given-names>
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<contrib contrib-type="author">
<name>
<surname>Yu</surname>
<given-names>Chong-Jen</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Yang</surname>
<given-names>Pan-Chyr</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
</contrib-group>
<aff id="aff1">Department of Internal Medicine,
<label>1</label>
Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan
<label>2</label>
</aff>
<author-notes>
<fn id="cor1">
<label>*</label>
<p>Corresponding author. Mailing address: Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan. Phone: 886-2-23123456, ext. 5401. Fax: 886-2-23971412. E-mail:
<email>sc4030@ha.mc.ntu.edu.tw</email>
.</p>
</fn>
</author-notes>
<pub-date pub-type="ppub">
<month>12</month>
<year>2005</year>
</pub-date>
<volume>12</volume>
<issue>12</issue>
<fpage>1455</fpage>
<lpage>1457</lpage>
<history>
<date date-type="received">
<day>14</day>
<month>2</month>
<year>2005</year>
</date>
<date date-type="rev-recd">
<day>12</day>
<month>4</month>
<year>2005</year>
</date>
<date date-type="accepted">
<day>29</day>
<month>9</month>
<year>2005</year>
</date>
</history>
<copyright-statement>Copyright © 2005, American Society for Microbiology</copyright-statement>
<copyright-year>2005</copyright-year>
<abstract>
<p>The serum antibodies to severe acute respiratory syndrome (SARS) coronavirus of 18 SARS patients were checked at 1 month and every 3 months after disease onset. All of them except one, who missed blood sampling at 1 month, tested positive for the immunoglobulin G (IgG) antibody at 1 month. Fifteen out of 17 tested positive for the IgM antibody at 1 month. The serum IgM antibody of most patients became undetectable within 6 months after the onset of SARS. The IgG antibody of all 17 patients, whose serum was checked 1 year after disease onset, remained positive.</p>
</abstract>
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