Pathology and Pathogenesis of Severe Acute Respiratory Syndrome
Identifieur interne : 000F23 ( Pmc/Checkpoint ); précédent : 000F22; suivant : 000F24Pathology and Pathogenesis of Severe Acute Respiratory Syndrome
Auteurs : Jiang Gu ; Christine KortewegSource :
- The American Journal of Pathology [ 0002-9440 ] ; 2007.
Abstract
Severe acute respiratory syndrome (SARS) is an emerging infectious viral disease characterized by severe clinical manifestations of the lower respiratory tract. The pathogenesis of SARS is highly complex, with multiple factors leading to severe injury in the lungs and dissemination of the virus to several other organs. The SARS coronavirus targets the epithelial cells of the respiratory tract, resulting in diffuse alveolar damage. Several organs/cell types may be infected in the course of the illness, including mucosal cells of the intestines, tubular epithelial cells of the kidneys, neurons of the brain, and several types of immune cells, and certain organs may suffer from indirect injury. Extensive studies have provided a basic understanding of the pathogenesis of this disease. In this review we describe the most significant pathological features of SARS, explore the etiological factors causing these pathological changes, and discuss the major pathogenetic mechanisms. The latter include dysregulation of cytokines/chemokines, deficiencies in the innate immune response, direct infection of immune cells, direct viral cytopathic effects, down-regulation of lung protective angiotensin converting enzyme 2, autoimmunity, and genetic factors. It seems that both abnormal immune responses and injury to immune cells may be key factors in the pathogenesis of this new disease.
Url:
DOI: 10.2353/ajpath.2007.061088
PubMed: 17392154
PubMed Central: 1829448
Affiliations:
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<front><div type="abstract" xml:lang="en"><p>Severe acute respiratory syndrome (SARS) is an emerging infectious viral disease characterized by severe clinical manifestations of the lower respiratory tract. The pathogenesis of SARS is highly complex, with multiple factors leading to severe injury in the lungs and dissemination of the virus to several other organs. The SARS coronavirus targets the epithelial cells of the respiratory tract, resulting in diffuse alveolar damage. Several organs/cell types may be infected in the course of the illness, including mucosal cells of the intestines, tubular epithelial cells of the kidneys, neurons of the brain, and several types of immune cells, and certain organs may suffer from indirect injury. Extensive studies have provided a basic understanding of the pathogenesis of this disease. In this review we describe the most significant pathological features of SARS, explore the etiological factors causing these pathological changes, and discuss the major pathogenetic mechanisms. The latter include dysregulation of cytokines/chemokines, deficiencies in the innate immune response, direct infection of immune cells, direct viral cytopathic effects, down-regulation of lung protective angiotensin converting enzyme 2, autoimmunity, and genetic factors. It seems that both abnormal immune responses and injury to immune cells may be key factors in the pathogenesis of this new disease.</p>
</div>
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<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Drosten, C" uniqKey="Drosten C">C Drosten</name>
</author>
<author><name sortKey="Gunther, S" uniqKey="Gunther S">S Gunther</name>
</author>
<author><name sortKey="Preiser, W" uniqKey="Preiser W">W Preiser</name>
</author>
<author><name sortKey="Van Der Werf, S" uniqKey="Van Der Werf S">S van der Werf</name>
</author>
<author><name sortKey="Brodt, Hr" uniqKey="Brodt H">HR Brodt</name>
</author>
<author><name sortKey="Becker, S" uniqKey="Becker S">S Becker</name>
</author>
<author><name sortKey="Rabenau, H" uniqKey="Rabenau H">H Rabenau</name>
</author>
<author><name sortKey="Panning, M" uniqKey="Panning M">M Panning</name>
</author>
<author><name sortKey="Kolesnikova, L" uniqKey="Kolesnikova L">L Kolesnikova</name>
</author>
<author><name sortKey="Fouchier, Ra" uniqKey="Fouchier R">RA Fouchier</name>
</author>
<author><name sortKey="Berger, A" uniqKey="Berger A">A Berger</name>
</author>
<author><name sortKey="Burguiere, Am" uniqKey="Burguiere A">AM Burguiere</name>
</author>
<author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J Cinatl</name>
</author>
<author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M Eickmann</name>
</author>
<author><name sortKey="Escriou, N" uniqKey="Escriou N">N Escriou</name>
</author>
<author><name sortKey="Grywna, K" uniqKey="Grywna K">K Grywna</name>
</author>
<author><name sortKey="Kramme, S" uniqKey="Kramme S">S Kramme</name>
</author>
<author><name sortKey="Manuguerra, Jc" uniqKey="Manuguerra J">JC Manuguerra</name>
</author>
<author><name sortKey="Muller, S" uniqKey="Muller S">S Muller</name>
</author>
<author><name sortKey="Rickerts, V" uniqKey="Rickerts V">V Rickerts</name>
</author>
<author><name sortKey="Sturmer, M" uniqKey="Sturmer M">M Sturmer</name>
</author>
<author><name sortKey="Vieth, S" uniqKey="Vieth S">S Vieth</name>
</author>
<author><name sortKey="Klenk, Hd" uniqKey="Klenk H">HD Klenk</name>
</author>
<author><name sortKey="Osterhaus, Ad" uniqKey="Osterhaus A">AD Osterhaus</name>
</author>
<author><name sortKey="Schmitz, H" uniqKey="Schmitz H">H Schmitz</name>
</author>
<author><name sortKey="Doerr, Hw" uniqKey="Doerr H">HW Doerr</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fouchier, Ra" uniqKey="Fouchier R">RA Fouchier</name>
</author>
<author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T Kuiken</name>
</author>
<author><name sortKey="Schutten, M" uniqKey="Schutten M">M Schutten</name>
</author>
<author><name sortKey="Van Amerongen, G" uniqKey="Van Amerongen G">G van Amerongen</name>
</author>
<author><name sortKey="Van Doornum, Gj" uniqKey="Van Doornum G">GJ van Doornum</name>
</author>
<author><name sortKey="Van Den Hoogen, Bg" uniqKey="Van Den Hoogen B">BG van den Hoogen</name>
</author>
<author><name sortKey="Peiris, M" uniqKey="Peiris M">M Peiris</name>
</author>
<author><name sortKey="Lim, W" uniqKey="Lim W">W Lim</name>
</author>
<author><name sortKey="Stohr, K" uniqKey="Stohr K">K Stohr</name>
</author>
<author><name sortKey="Osterhaus, Ad" uniqKey="Osterhaus A">AD Osterhaus</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Marra, Ma" uniqKey="Marra M">MA Marra</name>
</author>
<author><name sortKey="Jones, Sj" uniqKey="Jones S">SJ Jones</name>
</author>
<author><name sortKey="Astell, Cr" uniqKey="Astell C">CR Astell</name>
</author>
<author><name sortKey="Holt, Ra" uniqKey="Holt R">RA Holt</name>
</author>
<author><name sortKey="Brooks Wilson, A" uniqKey="Brooks Wilson A">A Brooks-Wilson</name>
</author>
<author><name sortKey="Butterfield, Ys" uniqKey="Butterfield Y">YS Butterfield</name>
</author>
<author><name sortKey="Khattra, J" uniqKey="Khattra J">J Khattra</name>
</author>
<author><name sortKey="Asano, Jk" uniqKey="Asano J">JK Asano</name>
</author>
<author><name sortKey="Barber, Sa" uniqKey="Barber S">SA Barber</name>
</author>
<author><name sortKey="Chan, Sy" uniqKey="Chan S">SY Chan</name>
</author>
<author><name sortKey="Cloutier, A" uniqKey="Cloutier A">A Cloutier</name>
</author>
<author><name sortKey="Coughlin, Sm" uniqKey="Coughlin S">SM Coughlin</name>
</author>
<author><name sortKey="Freeman, D" uniqKey="Freeman D">D Freeman</name>
</author>
<author><name sortKey="Girn, N" uniqKey="Girn N">N Girn</name>
</author>
<author><name sortKey="Griffith, Ol" uniqKey="Griffith O">OL Griffith</name>
</author>
<author><name sortKey="Leach, Sr" uniqKey="Leach S">SR Leach</name>
</author>
<author><name sortKey="Mayo, M" uniqKey="Mayo M">M Mayo</name>
</author>
<author><name sortKey="Mcdonald, H" uniqKey="Mcdonald H">H McDonald</name>
</author>
<author><name sortKey="Montgomery, Sb" uniqKey="Montgomery S">SB Montgomery</name>
</author>
<author><name sortKey="Pandoh, Pk" uniqKey="Pandoh P">PK Pandoh</name>
</author>
<author><name sortKey="Petrescu, As" uniqKey="Petrescu A">AS Petrescu</name>
</author>
<author><name sortKey="Robertson, Ag" uniqKey="Robertson A">AG Robertson</name>
</author>
<author><name sortKey="Schein, Je" uniqKey="Schein J">JE Schein</name>
</author>
<author><name sortKey="Siddiqui, A" uniqKey="Siddiqui A">A Siddiqui</name>
</author>
<author><name sortKey="Smailus, De" uniqKey="Smailus D">DE Smailus</name>
</author>
<author><name sortKey="Stott, Jm" uniqKey="Stott J">JM Stott</name>
</author>
<author><name sortKey="Yang, Gs" uniqKey="Yang G">GS Yang</name>
</author>
<author><name sortKey="Plummer, F" uniqKey="Plummer F">F Plummer</name>
</author>
<author><name sortKey="Andonov, A" uniqKey="Andonov A">A Andonov</name>
</author>
<author><name sortKey="Artsob, H" uniqKey="Artsob H">H Artsob</name>
</author>
<author><name sortKey="Bastien, N" uniqKey="Bastien N">N Bastien</name>
</author>
<author><name sortKey="Bernard, K" uniqKey="Bernard K">K Bernard</name>
</author>
<author><name sortKey="Booth, Tf" uniqKey="Booth T">TF Booth</name>
</author>
<author><name sortKey="Bowness, D" uniqKey="Bowness D">D Bowness</name>
</author>
<author><name sortKey="Czub, M" uniqKey="Czub M">M Czub</name>
</author>
<author><name sortKey="Drebot, M" uniqKey="Drebot M">M Drebot</name>
</author>
<author><name sortKey="Fernando, L" uniqKey="Fernando L">L Fernando</name>
</author>
<author><name sortKey="Flick, R" uniqKey="Flick R">R Flick</name>
</author>
<author><name sortKey="Garbutt, M" uniqKey="Garbutt M">M Garbutt</name>
</author>
<author><name sortKey="Gray, M" uniqKey="Gray M">M Gray</name>
</author>
<author><name sortKey="Grolla, A" uniqKey="Grolla A">A Grolla</name>
</author>
<author><name sortKey="Jones, S" uniqKey="Jones S">S Jones</name>
</author>
<author><name sortKey="Feldmann, H" uniqKey="Feldmann H">H Feldmann</name>
</author>
<author><name sortKey="Meyers, A" uniqKey="Meyers A">A Meyers</name>
</author>
<author><name sortKey="Kabani, A" uniqKey="Kabani A">A Kabani</name>
</author>
<author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name>
</author>
<author><name sortKey="Normand, S" uniqKey="Normand S">S Normand</name>
</author>
<author><name sortKey="Stroher, U" uniqKey="Stroher U">U Stroher</name>
</author>
<author><name sortKey="Tipples, Ga" uniqKey="Tipples G">GA Tipples</name>
</author>
<author><name sortKey="Tyler, S" uniqKey="Tyler S">S Tyler</name>
</author>
<author><name sortKey="Vogrig, R" uniqKey="Vogrig R">R Vogrig</name>
</author>
<author><name sortKey="Ward, D" uniqKey="Ward D">D Ward</name>
</author>
<author><name sortKey="Watson, B" uniqKey="Watson B">B Watson</name>
</author>
<author><name sortKey="Brunham, Rc" uniqKey="Brunham R">RC Brunham</name>
</author>
<author><name sortKey="Krajden, M" uniqKey="Krajden M">M Krajden</name>
</author>
<author><name sortKey="Petric, M" uniqKey="Petric M">M Petric</name>
</author>
<author><name sortKey="Skowronski, Dm" uniqKey="Skowronski D">DM Skowronski</name>
</author>
<author><name sortKey="Upton, C" uniqKey="Upton C">C Upton</name>
</author>
<author><name sortKey="Roper, Rl" uniqKey="Roper R">RL Roper</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y Guan</name>
</author>
<author><name sortKey="Zheng, Bj" uniqKey="Zheng B">BJ Zheng</name>
</author>
<author><name sortKey="He, Yq" uniqKey="He Y">YQ He</name>
</author>
<author><name sortKey="Liu, Xl" uniqKey="Liu X">XL Liu</name>
</author>
<author><name sortKey="Zhuang, Zx" uniqKey="Zhuang Z">ZX Zhuang</name>
</author>
<author><name sortKey="Cheung, Cl" uniqKey="Cheung C">CL Cheung</name>
</author>
<author><name sortKey="Luo, Sw" uniqKey="Luo S">SW Luo</name>
</author>
<author><name sortKey="Li, Ph" uniqKey="Li P">PH Li</name>
</author>
<author><name sortKey="Zhang, Lj" uniqKey="Zhang L">LJ Zhang</name>
</author>
<author><name sortKey="Guan, Yj" uniqKey="Guan Y">YJ Guan</name>
</author>
<author><name sortKey="Butt, Km" uniqKey="Butt K">KM Butt</name>
</author>
<author><name sortKey="Wong, Kl" uniqKey="Wong K">KL Wong</name>
</author>
<author><name sortKey="Chan, Kw" uniqKey="Chan K">KW Chan</name>
</author>
<author><name sortKey="Lim, W" uniqKey="Lim W">W Lim</name>
</author>
<author><name sortKey="Shortridge, Kf" uniqKey="Shortridge K">KF Shortridge</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
<author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS Peiris</name>
</author>
<author><name sortKey="Poon, Ll" uniqKey="Poon L">LL Poon</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Li, W" uniqKey="Li W">W Li</name>
</author>
<author><name sortKey="Shi, Z" uniqKey="Shi Z">Z Shi</name>
</author>
<author><name sortKey="Yu, M" uniqKey="Yu M">M Yu</name>
</author>
<author><name sortKey="Ren, W" uniqKey="Ren W">W Ren</name>
</author>
<author><name sortKey="Smith, C" uniqKey="Smith C">C Smith</name>
</author>
<author><name sortKey="Epstein, Jh" uniqKey="Epstein J">JH Epstein</name>
</author>
<author><name sortKey="Wang, H" uniqKey="Wang H">H Wang</name>
</author>
<author><name sortKey="Crameri, G" uniqKey="Crameri G">G Crameri</name>
</author>
<author><name sortKey="Hu, Z" uniqKey="Hu Z">Z Hu</name>
</author>
<author><name sortKey="Zhang, H" uniqKey="Zhang H">H Zhang</name>
</author>
<author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name>
</author>
<author><name sortKey="Mceachern, J" uniqKey="Mceachern J">J McEachern</name>
</author>
<author><name sortKey="Field, H" uniqKey="Field H">H Field</name>
</author>
<author><name sortKey="Daszak, P" uniqKey="Daszak P">P Daszak</name>
</author>
<author><name sortKey="Eaton, Bt" uniqKey="Eaton B">BT Eaton</name>
</author>
<author><name sortKey="Zhang, S" uniqKey="Zhang S">S Zhang</name>
</author>
<author><name sortKey="Wang, Lf" uniqKey="Wang L">LF Wang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS Peiris</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
<author><name sortKey="Osterhaus, Ad" uniqKey="Osterhaus A">AD Osterhaus</name>
</author>
<author><name sortKey="Stohr, K" uniqKey="Stohr K">K Stohr</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name>
</author>
<author><name sortKey="Poon, Ll" uniqKey="Poon L">LL Poon</name>
</author>
<author><name sortKey="Cheng, Vc" uniqKey="Cheng V">VC Cheng</name>
</author>
<author><name sortKey="Guan, Y" uniqKey="Guan Y">Y Guan</name>
</author>
<author><name sortKey="Hung, If" uniqKey="Hung I">IF Hung</name>
</author>
<author><name sortKey="Kong, J" uniqKey="Kong J">J Kong</name>
</author>
<author><name sortKey="Yam, Ly" uniqKey="Yam L">LY Yam</name>
</author>
<author><name sortKey="Seto, Wh" uniqKey="Seto W">WH Seto</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
<author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS Peiris</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Donnelly, Ca" uniqKey="Donnelly C">CA Donnelly</name>
</author>
<author><name sortKey="Chani, Ac" uniqKey="Chani A">AC Chani</name>
</author>
<author><name sortKey="Leung, Gm" uniqKey="Leung G">GM Leung</name>
</author>
<author><name sortKey="Hedley, Aj" uniqKey="Hedley A">AJ Hedley</name>
</author>
<author><name sortKey="Fraser, C" uniqKey="Fraser C">C Fraser</name>
</author>
<author><name sortKey="Riley, S" uniqKey="Riley S">S Riley</name>
</author>
<author><name sortKey="Abu Raddad, Lj" uniqKey="Abu Raddad L">LJ Abu-Raddad</name>
</author>
<author><name sortKey="Ho, Lm" uniqKey="Ho L">LM Ho</name>
</author>
<author><name sortKey="Thach, Tq" uniqKey="Thach T">TQ Thach</name>
</author>
<author><name sortKey="Chau, P" uniqKey="Chau P">P Chau</name>
</author>
<author><name sortKey="Chan, Kp" uniqKey="Chan K">KP Chan</name>
</author>
<author><name sortKey="Lam, Th" uniqKey="Lam T">TH Lam</name>
</author>
<author><name sortKey="Tse, Ly" uniqKey="Tse L">LY Tse</name>
</author>
<author><name sortKey="Tsang, T" uniqKey="Tsang T">T Tsang</name>
</author>
<author><name sortKey="Liu, Sh" uniqKey="Liu S">SH Liu</name>
</author>
<author><name sortKey="Kong, Jh" uniqKey="Kong J">JH Kong</name>
</author>
<author><name sortKey="Lau, Em" uniqKey="Lau E">EM Lau</name>
</author>
<author><name sortKey="Ferguson, Nm" uniqKey="Ferguson N">NM Ferguson</name>
</author>
<author><name sortKey="Anderson, Rm" uniqKey="Anderson R">RM Anderson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, Hly" uniqKey="Chan H">HLY Chan</name>
</author>
<author><name sortKey="Leung, Wk" uniqKey="Leung W">WK Leung</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Chan, Pks" uniqKey="Chan P">PKS Chan</name>
</author>
<author><name sortKey="Lee, N" uniqKey="Lee N">N Lee</name>
</author>
<author><name sortKey="Wu, A" uniqKey="Wu A">A Wu</name>
</author>
<author><name sortKey="Tam, Jsl" uniqKey="Tam J">JSL Tam</name>
</author>
<author><name sortKey="Sung, Jjy" uniqKey="Sung J">JJY Sung</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="He, Z" uniqKey="He Z">Z He</name>
</author>
<author><name sortKey="Zhao, C" uniqKey="Zhao C">C Zhao</name>
</author>
<author><name sortKey="Dong, Q" uniqKey="Dong Q">Q Dong</name>
</author>
<author><name sortKey="Zhuang, H" uniqKey="Zhuang H">H Zhuang</name>
</author>
<author><name sortKey="Song, S" uniqKey="Song S">S Song</name>
</author>
<author><name sortKey="Peng, G" uniqKey="Peng G">G Peng</name>
</author>
<author><name sortKey="Dwyer, De" uniqKey="Dwyer D">DE Dwyer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wong, Rsm" uniqKey="Wong R">RSM Wong</name>
</author>
<author><name sortKey="Wu, A" uniqKey="Wu A">A Wu</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Lee, N" uniqKey="Lee N">N Lee</name>
</author>
<author><name sortKey="Lam, Cwk" uniqKey="Lam C">CWK Lam</name>
</author>
<author><name sortKey="Wong, Ck" uniqKey="Wong C">CK Wong</name>
</author>
<author><name sortKey="Chan, Pks" uniqKey="Chan P">PKS Chan</name>
</author>
<author><name sortKey="Margaret, Hln" uniqKey="Margaret H">HLN Margaret</name>
</author>
<author><name sortKey="Yu, Lm" uniqKey="Yu L">LM Yu</name>
</author>
<author><name sortKey="Hui, Ds" uniqKey="Hui D">DS Hui</name>
</author>
<author><name sortKey="Tam, Js" uniqKey="Tam J">JS Tam</name>
</author>
<author><name sortKey="Cheng, G" uniqKey="Cheng G">G Cheng</name>
</author>
<author><name sortKey="Sung, Jjy" uniqKey="Sung J">JJY Sung</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ding, Yq" uniqKey="Ding Y">YQ Ding</name>
</author>
<author><name sortKey="Wang, Hj" uniqKey="Wang H">HJ Wang</name>
</author>
<author><name sortKey="Shen, H" uniqKey="Shen H">H Shen</name>
</author>
<author><name sortKey="Li, Zg" uniqKey="Li Z">ZG Li</name>
</author>
<author><name sortKey="Geng, J" uniqKey="Geng J">J Geng</name>
</author>
<author><name sortKey="Han, Hx" uniqKey="Han H">HX Han</name>
</author>
<author><name sortKey="Cai, Jj" uniqKey="Cai J">JJ Cai</name>
</author>
<author><name sortKey="Li, X" uniqKey="Li X">X Li</name>
</author>
<author><name sortKey="Kang, W" uniqKey="Kang W">W Kang</name>
</author>
<author><name sortKey="Weng, Ds" uniqKey="Weng D">DS Weng</name>
</author>
<author><name sortKey="Lu, Yd" uniqKey="Lu Y">YD Lu</name>
</author>
<author><name sortKey="Wu, Dh" uniqKey="Wu D">DH Wu</name>
</author>
<author><name sortKey="He, L" uniqKey="He L">L He</name>
</author>
<author><name sortKey="Yao, Kt" uniqKey="Yao K">KT Yao</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lang, Zw" uniqKey="Lang Z">ZW Lang</name>
</author>
<author><name sortKey="Zhang, Lj" uniqKey="Zhang L">LJ Zhang</name>
</author>
<author><name sortKey="Zhang, Sj" uniqKey="Zhang S">SJ Zhang</name>
</author>
<author><name sortKey="Meng, X" uniqKey="Meng X">X Meng</name>
</author>
<author><name sortKey="Li, Jq" uniqKey="Li J">JQ Li</name>
</author>
<author><name sortKey="Song, Cz" uniqKey="Song C">CZ Song</name>
</author>
<author><name sortKey="Sun, L" uniqKey="Sun L">L Sun</name>
</author>
<author><name sortKey="Zhou, Ys" uniqKey="Zhou Y">YS Zhou</name>
</author>
<author><name sortKey="Dwyer, De" uniqKey="Dwyer D">DE Dwyer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tse, Gmk" uniqKey="Tse G">GMK Tse</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Chan, Pks" uniqKey="Chan P">PKS Chan</name>
</author>
<author><name sortKey="Lo, Awi" uniqKey="Lo A">AWI Lo</name>
</author>
<author><name sortKey="Ng, Kc" uniqKey="Ng K">KC Ng</name>
</author>
<author><name sortKey="Wu, A" uniqKey="Wu A">A Wu</name>
</author>
<author><name sortKey="Lee, N" uniqKey="Lee N">N Lee</name>
</author>
<author><name sortKey="Wong, Hc" uniqKey="Wong H">HC Wong</name>
</author>
<author><name sortKey="Mak, Sm" uniqKey="Mak S">SM Mak</name>
</author>
<author><name sortKey="Chan, Kf" uniqKey="Chan K">KF Chan</name>
</author>
<author><name sortKey="Hui, Dsc" uniqKey="Hui D">DSC Hui</name>
</author>
<author><name sortKey="Sung, Jjy" uniqKey="Sung J">JJY Sung</name>
</author>
<author><name sortKey="Ng, Hk" uniqKey="Ng H">HK Ng</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gu, J" uniqKey="Gu J">J Gu</name>
</author>
<author><name sortKey="Gong, Ec" uniqKey="Gong E">EC Gong</name>
</author>
<author><name sortKey="Zhang, B" uniqKey="Zhang B">B Zhang</name>
</author>
<author><name sortKey="Zheng, J" uniqKey="Zheng J">J Zheng</name>
</author>
<author><name sortKey="Gao, Zf" uniqKey="Gao Z">ZF Gao</name>
</author>
<author><name sortKey="Zhong, Yf" uniqKey="Zhong Y">YF Zhong</name>
</author>
<author><name sortKey="Zou, Wz" uniqKey="Zou W">WZ Zou</name>
</author>
<author><name sortKey="Zhan, J" uniqKey="Zhan J">J Zhan</name>
</author>
<author><name sortKey="Wang, Sl" uniqKey="Wang S">SL Wang</name>
</author>
<author><name sortKey="Xie, Zg" uniqKey="Xie Z">ZG Xie</name>
</author>
<author><name sortKey="Zhuang, H" uniqKey="Zhuang H">H Zhuang</name>
</author>
<author><name sortKey="Wu, Bq" uniqKey="Wu B">BQ Wu</name>
</author>
<author><name sortKey="Zhong, Hh" uniqKey="Zhong H">HH Zhong</name>
</author>
<author><name sortKey="Shao, Hq" uniqKey="Shao H">HQ Shao</name>
</author>
<author><name sortKey="Fang, Wg" uniqKey="Fang W">WG Fang</name>
</author>
<author><name sortKey="Gao, Dx" uniqKey="Gao D">DX Gao</name>
</author>
<author><name sortKey="Pei, F" uniqKey="Pei F">F Pei</name>
</author>
<author><name sortKey="Li, Xw" uniqKey="Li X">XW Li</name>
</author>
<author><name sortKey="He, Zp" uniqKey="He Z">ZP He</name>
</author>
<author><name sortKey="Xu, Dz" uniqKey="Xu D">DZ Xu</name>
</author>
<author><name sortKey="Shi, Xy" uniqKey="Shi X">XY Shi</name>
</author>
<author><name sortKey="Anderson, Vm" uniqKey="Anderson V">VM Anderson</name>
</author>
<author><name sortKey="Leong, Asy" uniqKey="Leong A">ASY Leong</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nicholls, Jm" uniqKey="Nicholls J">JM Nicholls</name>
</author>
<author><name sortKey="Poon, Ll" uniqKey="Poon L">LL Poon</name>
</author>
<author><name sortKey="Lee, Kc" uniqKey="Lee K">KC Lee</name>
</author>
<author><name sortKey="Ng, Wf" uniqKey="Ng W">WF Ng</name>
</author>
<author><name sortKey="Lai, St" uniqKey="Lai S">ST Lai</name>
</author>
<author><name sortKey="Leung, Cy" uniqKey="Leung C">CY Leung</name>
</author>
<author><name sortKey="Chu, Cm" uniqKey="Chu C">CM Chu</name>
</author>
<author><name sortKey="Hui, Pk" uniqKey="Hui P">PK Hui</name>
</author>
<author><name sortKey="Mak, Kl" uniqKey="Mak K">KL Mak</name>
</author>
<author><name sortKey="Lim, W" uniqKey="Lim W">W Lim</name>
</author>
<author><name sortKey="Yan, Kw" uniqKey="Yan K">KW Yan</name>
</author>
<author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name>
</author>
<author><name sortKey="Tsang, Nc" uniqKey="Tsang N">NC Tsang</name>
</author>
<author><name sortKey="Guan, Y" uniqKey="Guan Y">Y Guan</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
<author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS Peiris</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chong, Py" uniqKey="Chong P">PY Chong</name>
</author>
<author><name sortKey="Chui, P" uniqKey="Chui P">P Chui</name>
</author>
<author><name sortKey="Ling, Ae" uniqKey="Ling A">AE Ling</name>
</author>
<author><name sortKey="Franks, Tj" uniqKey="Franks T">TJ Franks</name>
</author>
<author><name sortKey="Tai, Dy" uniqKey="Tai D">DY Tai</name>
</author>
<author><name sortKey="Leo, Ys" uniqKey="Leo Y">YS Leo</name>
</author>
<author><name sortKey="Kaw, Gj" uniqKey="Kaw G">GJ Kaw</name>
</author>
<author><name sortKey="Wansaicheong, G" uniqKey="Wansaicheong G">G Wansaicheong</name>
</author>
<author><name sortKey="Chan, Kp" uniqKey="Chan K">KP Chan</name>
</author>
<author><name sortKey="Ean Oon, Ll" uniqKey="Ean Oon L">LL Ean Oon</name>
</author>
<author><name sortKey="Teo, Es" uniqKey="Teo E">ES Teo</name>
</author>
<author><name sortKey="Tan, Kb" uniqKey="Tan K">KB Tan</name>
</author>
<author><name sortKey="Nakajima, N" uniqKey="Nakajima N">N Nakajima</name>
</author>
<author><name sortKey="Sata, T" uniqKey="Sata T">T Sata</name>
</author>
<author><name sortKey="Travis, Wd" uniqKey="Travis W">WD Travis</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cheung, Oy" uniqKey="Cheung O">OY Cheung</name>
</author>
<author><name sortKey="Chan, Jw" uniqKey="Chan J">JW Chan</name>
</author>
<author><name sortKey="Ng, Ck" uniqKey="Ng C">CK Ng</name>
</author>
<author><name sortKey="Koo, Ck" uniqKey="Koo C">CK Koo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hwang, Dm" uniqKey="Hwang D">DM Hwang</name>
</author>
<author><name sortKey="Chamberlain, Dw" uniqKey="Chamberlain D">DW Chamberlain</name>
</author>
<author><name sortKey="Poutanen, Sm" uniqKey="Poutanen S">SM Poutanen</name>
</author>
<author><name sortKey="Low, De" uniqKey="Low D">DE Low</name>
</author>
<author><name sortKey="Asa, Sl" uniqKey="Asa S">SL Asa</name>
</author>
<author><name sortKey="Butany, J" uniqKey="Butany J">J Butany</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Franks, Tj" uniqKey="Franks T">TJ Franks</name>
</author>
<author><name sortKey="Chong, Py" uniqKey="Chong P">PY Chong</name>
</author>
<author><name sortKey="Chui, P" uniqKey="Chui P">P Chui</name>
</author>
<author><name sortKey="Galvin, Jr" uniqKey="Galvin J">JR Galvin</name>
</author>
<author><name sortKey="Lourens, Rm" uniqKey="Lourens R">RM Lourens</name>
</author>
<author><name sortKey="Reid, Ah" uniqKey="Reid A">AH Reid</name>
</author>
<author><name sortKey="Selbs, E" uniqKey="Selbs E">E Selbs</name>
</author>
<author><name sortKey="Mcevoy, Cpl" uniqKey="Mcevoy C">CPL McEvoy</name>
</author>
<author><name sortKey="Hayden, Cdl" uniqKey="Hayden C">CDL Hayden</name>
</author>
<author><name sortKey="Fukuoka, J" uniqKey="Fukuoka J">J Fukuoka</name>
</author>
<author><name sortKey="Taubenberger, Jk" uniqKey="Taubenberger J">JK Taubenberger</name>
</author>
<author><name sortKey="Travis, Wd" uniqKey="Travis W">WD Travis</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hsiao, Ch" uniqKey="Hsiao C">CH Hsiao</name>
</author>
<author><name sortKey="Wu, Mz" uniqKey="Wu M">MZ Wu</name>
</author>
<author><name sortKey="Chen, Cl" uniqKey="Chen C">CL Chen</name>
</author>
<author><name sortKey="Hsueh, Pr" uniqKey="Hsueh P">PR Hsueh</name>
</author>
<author><name sortKey="Hsieh, Sw" uniqKey="Hsieh S">SW Hsieh</name>
</author>
<author><name sortKey="Yang, Pc" uniqKey="Yang P">PC Yang</name>
</author>
<author><name sortKey="Su, Ij" uniqKey="Su I">IJ Su</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nakajima, N" uniqKey="Nakajima N">N Nakajima</name>
</author>
<author><name sortKey="Asahi Ozaki, Y" uniqKey="Asahi Ozaki Y">Y Asahi-Ozaki</name>
</author>
<author><name sortKey="Nagata, N" uniqKey="Nagata N">N Nagata</name>
</author>
<author><name sortKey="Yko, S" uniqKey="Yko S">S Yko</name>
</author>
<author><name sortKey="Dizon, F" uniqKey="Dizon F">F Dizon</name>
</author>
<author><name sortKey="Paladin, Fj" uniqKey="Paladin F">FJ Paladin</name>
</author>
<author><name sortKey="Olveda, Rm" uniqKey="Olveda R">RM Olveda</name>
</author>
<author><name sortKey="Odagiri, T" uniqKey="Odagiri T">T Odagiri</name>
</author>
<author><name sortKey="Masato, T" uniqKey="Masato T">T Masato</name>
</author>
<author><name sortKey="Sata, T" uniqKey="Sata T">T Sata</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="He, L" uniqKey="He L">L He</name>
</author>
<author><name sortKey="Ding, Y" uniqKey="Ding Y">Y Ding</name>
</author>
<author><name sortKey="Zhang, Q" uniqKey="Zhang Q">Q Zhang</name>
</author>
<author><name sortKey="Che, X" uniqKey="Che X">X Che</name>
</author>
<author><name sortKey="He, Y" uniqKey="He Y">Y He</name>
</author>
<author><name sortKey="Shen, H" uniqKey="Shen H">H Shen</name>
</author>
<author><name sortKey="Wang, H" uniqKey="Wang H">H Wang</name>
</author>
<author><name sortKey="Li, Z" uniqKey="Li Z">Z Li</name>
</author>
<author><name sortKey="Zhao, L" uniqKey="Zhao L">L Zhao</name>
</author>
<author><name sortKey="Geng, J" uniqKey="Geng J">J Geng</name>
</author>
<author><name sortKey="Deng, Y" uniqKey="Deng Y">Y Deng</name>
</author>
<author><name sortKey="Yang, L" uniqKey="Yang L">L Yang</name>
</author>
<author><name sortKey="Li, J" uniqKey="Li J">J Li</name>
</author>
<author><name sortKey="Cai, J" uniqKey="Cai J">J Cai</name>
</author>
<author><name sortKey="Qiu, L" uniqKey="Qiu L">L Qiu</name>
</author>
<author><name sortKey="Wen, K" uniqKey="Wen K">K Wen</name>
</author>
<author><name sortKey="Xu, X" uniqKey="Xu X">X Xu</name>
</author>
<author><name sortKey="Jiang, S" uniqKey="Jiang S">S Jiang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shieh, Wj" uniqKey="Shieh W">WJ Shieh</name>
</author>
<author><name sortKey="Hsiao, Ch" uniqKey="Hsiao C">CH Hsiao</name>
</author>
<author><name sortKey="Paddock, Cd" uniqKey="Paddock C">CD Paddock</name>
</author>
<author><name sortKey="Guarner, J" uniqKey="Guarner J">J Guarner</name>
</author>
<author><name sortKey="Goldsmith, Cs" uniqKey="Goldsmith C">CS Goldsmith</name>
</author>
<author><name sortKey="Tatti, K" uniqKey="Tatti K">K Tatti</name>
</author>
<author><name sortKey="Packard, M" uniqKey="Packard M">M Packard</name>
</author>
<author><name sortKey="Mueller, L" uniqKey="Mueller L">L Mueller</name>
</author>
<author><name sortKey="Wu, Mz" uniqKey="Wu M">MZ Wu</name>
</author>
<author><name sortKey="Rollin, P" uniqKey="Rollin P">P Rollin</name>
</author>
<author><name sortKey="Su, Ij" uniqKey="Su I">IJ Su</name>
</author>
<author><name sortKey="Zaki, Sr" uniqKey="Zaki S">SR Zaki</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hsueh, Pr" uniqKey="Hsueh P">PR Hsueh</name>
</author>
<author><name sortKey="Chen, Pj" uniqKey="Chen P">PJ Chen</name>
</author>
<author><name sortKey="Hsiao, Ch" uniqKey="Hsiao C">CH Hsiao</name>
</author>
<author><name sortKey="Yeh, Sh" uniqKey="Yeh S">SH Yeh</name>
</author>
<author><name sortKey="Cheng, Wc" uniqKey="Cheng W">WC Cheng</name>
</author>
<author><name sortKey="Wang, Jl" uniqKey="Wang J">JL Wang</name>
</author>
<author><name sortKey="Chiang, Bl" uniqKey="Chiang B">BL Chiang</name>
</author>
<author><name sortKey="Chang, Sc" uniqKey="Chang S">SC Chang</name>
</author>
<author><name sortKey="Chang, Fy" uniqKey="Chang F">FY Chang</name>
</author>
<author><name sortKey="Wong, Ww" uniqKey="Wong W">WW Wong</name>
</author>
<author><name sortKey="Kao, Cl" uniqKey="Kao C">CL Kao</name>
</author>
<author><name sortKey="Yang, Pc" uniqKey="Yang P">PC Yang</name>
</author>
<author><name sortKey="Sars Research Group Of National Taiwan University College Of Medicine And National Taiwan University Hospital" uniqKey="Sars Research Group Of National Taiwan University College Of Medicine And National Taiwan University Hospital">SARS Research Group of National Taiwan University College of Medicine and National Taiwan University Hospital</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yen, Yt" uniqKey="Yen Y">YT Yen</name>
</author>
<author><name sortKey="Liao, F" uniqKey="Liao F">F Liao</name>
</author>
<author><name sortKey="Hsiao, Ch" uniqKey="Hsiao C">CH Hsiao</name>
</author>
<author><name sortKey="Kao, Cl" uniqKey="Kao C">CL Kao</name>
</author>
<author><name sortKey="Chen, Yc" uniqKey="Chen Y">YC Chen</name>
</author>
<author><name sortKey="Wu Hsieh, Ba" uniqKey="Wu Hsieh B">BA Wu-Hsieh</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhan, J" uniqKey="Zhan J">J Zhan</name>
</author>
<author><name sortKey="Deng, R" uniqKey="Deng R">R Deng</name>
</author>
<author><name sortKey="Tang, J" uniqKey="Tang J">J Tang</name>
</author>
<author><name sortKey="Zhang, B" uniqKey="Zhang B">B Zhang</name>
</author>
<author><name sortKey="Tang, Y" uniqKey="Tang Y">Y Tang</name>
</author>
<author><name sortKey="Wang, Jk" uniqKey="Wang J">JK Wang</name>
</author>
<author><name sortKey="Li, F" uniqKey="Li F">F Li</name>
</author>
<author><name sortKey="Anderson, Vm" uniqKey="Anderson V">VM Anderson</name>
</author>
<author><name sortKey="Mcnutt, Ma" uniqKey="Mcnutt M">MA McNutt</name>
</author>
<author><name sortKey="Gu, J" uniqKey="Gu J">J Gu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nicholls, Jm" uniqKey="Nicholls J">JM Nicholls</name>
</author>
<author><name sortKey="Butany, J" uniqKey="Butany J">J Butany</name>
</author>
<author><name sortKey="Poon, Ll" uniqKey="Poon L">LL Poon</name>
</author>
<author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name>
</author>
<author><name sortKey="Beh, Sl" uniqKey="Beh S">SL Beh</name>
</author>
<author><name sortKey="Poutanen, S" uniqKey="Poutanen S">S Poutanen</name>
</author>
<author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS Peiris</name>
</author>
<author><name sortKey="Wong, M" uniqKey="Wong M">M Wong</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, Ws" uniqKey="Chan W">WS Chan</name>
</author>
<author><name sortKey="Wu, C" uniqKey="Wu C">C Wu</name>
</author>
<author><name sortKey="Chow, Sc" uniqKey="Chow S">SC Chow</name>
</author>
<author><name sortKey="Cheung, T" uniqKey="Cheung T">T Cheung</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Leung, Wk" uniqKey="Leung W">WK Leung</name>
</author>
<author><name sortKey="Chan, Pk" uniqKey="Chan P">PK Chan</name>
</author>
<author><name sortKey="Lee, Kc" uniqKey="Lee K">KC Lee</name>
</author>
<author><name sortKey="Ng, Hk" uniqKey="Ng H">HK Ng</name>
</author>
<author><name sortKey="Au, Dm" uniqKey="Au D">DM Au</name>
</author>
<author><name sortKey="Lo, Aw" uniqKey="Lo A">AW Lo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ding, Yq" uniqKey="Ding Y">YQ Ding</name>
</author>
<author><name sortKey="He, L" uniqKey="He L">L He</name>
</author>
<author><name sortKey="Zhang, Ql" uniqKey="Zhang Q">QL Zhang</name>
</author>
<author><name sortKey="Huang, Zx" uniqKey="Huang Z">ZX Huang</name>
</author>
<author><name sortKey="Che, Xy" uniqKey="Che X">XY Che</name>
</author>
<author><name sortKey="Hou, Jl" uniqKey="Hou J">JL Hou</name>
</author>
<author><name sortKey="Wang, Hj" uniqKey="Wang H">HJ Wang</name>
</author>
<author><name sortKey="Shen, H" uniqKey="Shen H">H Shen</name>
</author>
<author><name sortKey="Qiu, Lw" uniqKey="Qiu L">LW Qiu</name>
</author>
<author><name sortKey="Li, Zg" uniqKey="Li Z">ZG Li</name>
</author>
<author><name sortKey="Geng, J" uniqKey="Geng J">J Geng</name>
</author>
<author><name sortKey="Cai, Jj" uniqKey="Cai J">JJ Cai</name>
</author>
<author><name sortKey="Han, Hx" uniqKey="Han H">HX Han</name>
</author>
<author><name sortKey="Li, X" uniqKey="Li X">X Li</name>
</author>
<author><name sortKey="Kang, W" uniqKey="Kang W">W Kang</name>
</author>
<author><name sortKey="Weng, Ds" uniqKey="Weng D">DS Weng</name>
</author>
<author><name sortKey="Liang, P" uniqKey="Liang P">P Liang</name>
</author>
<author><name sortKey="Jiang, Sb" uniqKey="Jiang S">SB Jiang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Tong, Jh" uniqKey="Tong J">JH Tong</name>
</author>
<author><name sortKey="Chan, Pk" uniqKey="Chan P">PK Chan</name>
</author>
<author><name sortKey="Au, Fw" uniqKey="Au F">FW Au</name>
</author>
<author><name sortKey="Chim, Ss" uniqKey="Chim S">SS Chim</name>
</author>
<author><name sortKey="Chan, Kc" uniqKey="Chan K">KC Chan</name>
</author>
<author><name sortKey="Cheung, Jl" uniqKey="Cheung J">JL Cheung</name>
</author>
<author><name sortKey="Liu, Ey" uniqKey="Liu E">EY Liu</name>
</author>
<author><name sortKey="Tse, Gm" uniqKey="Tse G">GM Tse</name>
</author>
<author><name sortKey="Lo, Aw" uniqKey="Lo A">AW Lo</name>
</author>
<author><name sortKey="Lo, Ym" uniqKey="Lo Y">YM Lo</name>
</author>
<author><name sortKey="Ng, Hk" uniqKey="Ng H">HK Ng</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chow, Kc" uniqKey="Chow K">KC Chow</name>
</author>
<author><name sortKey="Hsiao, Ch" uniqKey="Hsiao C">CH Hsiao</name>
</author>
<author><name sortKey="Lin, Ty" uniqKey="Lin T">TY Lin</name>
</author>
<author><name sortKey="Chen, Cl" uniqKey="Chen C">CL Chen</name>
</author>
<author><name sortKey="Chiou, Sh" uniqKey="Chiou S">SH Chiou</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ye, J" uniqKey="Ye J">J Ye</name>
</author>
<author><name sortKey="Zhang, B" uniqKey="Zhang B">B Zhang</name>
</author>
<author><name sortKey="Xu, J" uniqKey="Xu J">J Xu</name>
</author>
<author><name sortKey="Chang, Q" uniqKey="Chang Q">Q Chang</name>
</author>
<author><name sortKey="Mcnutt, Ma" uniqKey="Mcnutt M">MA McNutt</name>
</author>
<author><name sortKey="Korteweg, C" uniqKey="Korteweg C">C Korteweg</name>
</author>
<author><name sortKey="Gong, E" uniqKey="Gong E">E Gong</name>
</author>
<author><name sortKey="Gu, J" uniqKey="Gu J">J Gu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jiang, Y" uniqKey="Jiang Y">Y Jiang</name>
</author>
<author><name sortKey="Xu, J" uniqKey="Xu J">J Xu</name>
</author>
<author><name sortKey="Zhou, C" uniqKey="Zhou C">C Zhou</name>
</author>
<author><name sortKey="Wu, Z" uniqKey="Wu Z">Z Wu</name>
</author>
<author><name sortKey="Zhong, S" uniqKey="Zhong S">S Zhong</name>
</author>
<author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name>
</author>
<author><name sortKey="Luo, W" uniqKey="Luo W">W Luo</name>
</author>
<author><name sortKey="Chen, T" uniqKey="Chen T">T Chen</name>
</author>
<author><name sortKey="Qin, Q" uniqKey="Qin Q">Q Qin</name>
</author>
<author><name sortKey="Deng, P" uniqKey="Deng P">P Deng</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tang, Nl" uniqKey="Tang N">NL Tang</name>
</author>
<author><name sortKey="Chan, Pk" uniqKey="Chan P">PK Chan</name>
</author>
<author><name sortKey="Wong, Ck" uniqKey="Wong C">CK Wong</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Wu, Ak" uniqKey="Wu A">AK Wu</name>
</author>
<author><name sortKey="Sung, Ym" uniqKey="Sung Y">YM Sung</name>
</author>
<author><name sortKey="Hui, Ds" uniqKey="Hui D">DS Hui</name>
</author>
<author><name sortKey="Sung, Jj" uniqKey="Sung J">JJ Sung</name>
</author>
<author><name sortKey="Lam, Cw" uniqKey="Lam C">CW Lam</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Goldsmith, Cs" uniqKey="Goldsmith C">CS Goldsmith</name>
</author>
<author><name sortKey="Tatti, Km" uniqKey="Tatti K">KM Tatti</name>
</author>
<author><name sortKey="Ksiazek, Tg" uniqKey="Ksiazek T">TG Ksiazek</name>
</author>
<author><name sortKey="Rollin, Pe" uniqKey="Rollin P">PE Rollin</name>
</author>
<author><name sortKey="Comer, Ja" uniqKey="Comer J">JA Comer</name>
</author>
<author><name sortKey="Lee, Ww" uniqKey="Lee W">WW Lee</name>
</author>
<author><name sortKey="Rota, Pa" uniqKey="Rota P">PA Rota</name>
</author>
<author><name sortKey="Bankamp, B" uniqKey="Bankamp B">B Bankamp</name>
</author>
<author><name sortKey="Bellini, Wj" uniqKey="Bellini W">WJ Bellini</name>
</author>
<author><name sortKey="Zaki, Sr" uniqKey="Zaki S">SR Zaki</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Farcas, Ga" uniqKey="Farcas G">GA Farcas</name>
</author>
<author><name sortKey="Poutanen, Sm" uniqKey="Poutanen S">SM Poutanen</name>
</author>
<author><name sortKey="Mazzulli, T" uniqKey="Mazzulli T">T Mazzulli</name>
</author>
<author><name sortKey="Willey, Bm" uniqKey="Willey B">BM Willey</name>
</author>
<author><name sortKey="Butany, J" uniqKey="Butany J">J Butany</name>
</author>
<author><name sortKey="Asa, Sl" uniqKey="Asa S">SL Asa</name>
</author>
<author><name sortKey="Faure, P" uniqKey="Faure P">P Faure</name>
</author>
<author><name sortKey="Akhavan, P" uniqKey="Akhavan P">P Akhavan</name>
</author>
<author><name sortKey="Low, De" uniqKey="Low D">DE Low</name>
</author>
<author><name sortKey="Kain, Kc" uniqKey="Kain K">KC Kain</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ng, Wf" uniqKey="Ng W">WF Ng</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Lam, Ww" uniqKey="Lam W">WW Lam</name>
</author>
<author><name sortKey="Ng, Tk" uniqKey="Ng T">TK Ng</name>
</author>
<author><name sortKey="Lee, Kc" uniqKey="Lee K">KC Lee</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shi, X" uniqKey="Shi X">X Shi</name>
</author>
<author><name sortKey="Gong, E" uniqKey="Gong E">E Gong</name>
</author>
<author><name sortKey="Gao, D" uniqKey="Gao D">D Gao</name>
</author>
<author><name sortKey="Zhang, B" uniqKey="Zhang B">B Zhang</name>
</author>
<author><name sortKey="Zheng, J" uniqKey="Zheng J">J Zheng</name>
</author>
<author><name sortKey="Gao, Z" uniqKey="Gao Z">Z Gao</name>
</author>
<author><name sortKey="Zhong, Y" uniqKey="Zhong Y">Y Zhong</name>
</author>
<author><name sortKey="Zou, W" uniqKey="Zou W">W Zou</name>
</author>
<author><name sortKey="Wu, B" uniqKey="Wu B">B Wu</name>
</author>
<author><name sortKey="Fang, W" uniqKey="Fang W">W Fang</name>
</author>
<author><name sortKey="Liao, S" uniqKey="Liao S">S Liao</name>
</author>
<author><name sortKey="Wang, S" uniqKey="Wang S">S Wang</name>
</author>
<author><name sortKey="Xie, Z" uniqKey="Xie Z">Z Xie</name>
</author>
<author><name sortKey="Lu, M" uniqKey="Lu M">M Lu</name>
</author>
<author><name sortKey="Hou, L" uniqKey="Hou L">L Hou</name>
</author>
<author><name sortKey="Zhong, H" uniqKey="Zhong H">H Zhong</name>
</author>
<author><name sortKey="Shao, H" uniqKey="Shao H">H Shao</name>
</author>
<author><name sortKey="Li, N" uniqKey="Li N">N Li</name>
</author>
<author><name sortKey="Liu, C" uniqKey="Liu C">C Liu</name>
</author>
<author><name sortKey="Pei, F" uniqKey="Pei F">F Pei</name>
</author>
<author><name sortKey="Yang, J" uniqKey="Yang J">J Yang</name>
</author>
<author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name>
</author>
<author><name sortKey="Han, Z" uniqKey="Han Z">Z Han</name>
</author>
<author><name sortKey="Shi, X" uniqKey="Shi X">X Shi</name>
</author>
<author><name sortKey="Zhang, Q" uniqKey="Zhang Q">Q Zhang</name>
</author>
<author><name sortKey="You, J" uniqKey="You J">J You</name>
</author>
<author><name sortKey="Zhu, X" uniqKey="Zhu X">X Zhu</name>
</author>
<author><name sortKey="Gu, J" uniqKey="Gu J">J Gu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hung, Ec" uniqKey="Hung E">EC Hung</name>
</author>
<author><name sortKey="Chim, Ss" uniqKey="Chim S">SS Chim</name>
</author>
<author><name sortKey="Chan, Pk" uniqKey="Chan P">PK Chan</name>
</author>
<author><name sortKey="Chan, Pk" uniqKey="Chan P">PK Chan</name>
</author>
<author><name sortKey="Tong, Yk" uniqKey="Tong Y">YK Tong</name>
</author>
<author><name sortKey="Ng, Ek" uniqKey="Ng E">EK Ng</name>
</author>
<author><name sortKey="Chiu, Rw" uniqKey="Chiu R">RW Chiu</name>
</author>
<author><name sortKey="Leung, Cb" uniqKey="Leung C">CB Leung</name>
</author>
<author><name sortKey="Sung, Jj" uniqKey="Sung J">JJ Sung</name>
</author>
<author><name sortKey="Tam, Js" uniqKey="Tam J">JS Tam</name>
</author>
<author><name sortKey="Lo, Ym" uniqKey="Lo Y">YM Lo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lau, Kk" uniqKey="Lau K">KK Lau</name>
</author>
<author><name sortKey="Yu, Wc" uniqKey="Yu W">WC Yu</name>
</author>
<author><name sortKey="Chu, Cm" uniqKey="Chu C">CM Chu</name>
</author>
<author><name sortKey="Lau, St" uniqKey="Lau S">ST Lau</name>
</author>
<author><name sortKey="Sheng, B" uniqKey="Sheng B">B Sheng</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Xu, J" uniqKey="Xu J">J Xu</name>
</author>
<author><name sortKey="Zhong, S" uniqKey="Zhong S">S Zhong</name>
</author>
<author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name>
</author>
<author><name sortKey="Li, L" uniqKey="Li L">L Li</name>
</author>
<author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name>
</author>
<author><name sortKey="Wu, X" uniqKey="Wu X">X Wu</name>
</author>
<author><name sortKey="Li, Z" uniqKey="Li Z">Z Li</name>
</author>
<author><name sortKey="Deng, P" uniqKey="Deng P">P Deng</name>
</author>
<author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name>
</author>
<author><name sortKey="Zhong, N" uniqKey="Zhong N">N Zhong</name>
</author>
<author><name sortKey="Ding, Y" uniqKey="Ding Y">Y Ding</name>
</author>
<author><name sortKey="Jiang, Y" uniqKey="Jiang Y">Y Jiang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chu, Kh" uniqKey="Chu K">KH Chu</name>
</author>
<author><name sortKey="Tsang, Wk" uniqKey="Tsang W">WK Tsang</name>
</author>
<author><name sortKey="Tang, Cs" uniqKey="Tang C">CS Tang</name>
</author>
<author><name sortKey="Lam, Mf" uniqKey="Lam M">MF Lam</name>
</author>
<author><name sortKey="Lai, Fm" uniqKey="Lai F">FM Lai</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Fung, Ks" uniqKey="Fung K">KS Fung</name>
</author>
<author><name sortKey="Tang, Hl" uniqKey="Tang H">HL Tang</name>
</author>
<author><name sortKey="Yan, Ww" uniqKey="Yan W">WW Yan</name>
</author>
<author><name sortKey="Chan, Hw" uniqKey="Chan H">HW Chan</name>
</author>
<author><name sortKey="Lai, Ts" uniqKey="Lai T">TS Lai</name>
</author>
<author><name sortKey="Tong, Kl" uniqKey="Tong K">KL Tong</name>
</author>
<author><name sortKey="Lai, Kn" uniqKey="Lai K">KN Lai</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wu, Vc" uniqKey="Wu V">VC Wu</name>
</author>
<author><name sortKey="Hsueh, Pr" uniqKey="Hsueh P">PR Hsueh</name>
</author>
<author><name sortKey="Lin, Wc" uniqKey="Lin W">WC Lin</name>
</author>
<author><name sortKey="Huang, Jw" uniqKey="Huang J">JW Huang</name>
</author>
<author><name sortKey="Tsai, Hb" uniqKey="Tsai H">HB Tsai</name>
</author>
<author><name sortKey="Chen, Ym" uniqKey="Chen Y">YM Chen</name>
</author>
<author><name sortKey="Wu, Kd" uniqKey="Wu K">KD Wu</name>
</author>
<author><name sortKey="The Sars Research Group Of The National Taiwan" uniqKey="The Sars Research Group Of The National Taiwan">the SARS Research Group of the National Taiwan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Xu, J" uniqKey="Xu J">J Xu</name>
</author>
<author><name sortKey="Qi, L" uniqKey="Qi L">L Qi</name>
</author>
<author><name sortKey="Chi, X" uniqKey="Chi X">X Chi</name>
</author>
<author><name sortKey="Yang, J" uniqKey="Yang J">J Yang</name>
</author>
<author><name sortKey="Wei, X" uniqKey="Wei X">X Wei</name>
</author>
<author><name sortKey="Gong, E" uniqKey="Gong E">E Gong</name>
</author>
<author><name sortKey="Peh, S" uniqKey="Peh S">S Peh</name>
</author>
<author><name sortKey="Gu, J" uniqKey="Gu J">J Gu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Leung, Wk" uniqKey="Leung W">WK Leung</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Chan, Pk" uniqKey="Chan P">PK Chan</name>
</author>
<author><name sortKey="Chan, Hl" uniqKey="Chan H">HL Chan</name>
</author>
<author><name sortKey="Wu, Ak" uniqKey="Wu A">AK Wu</name>
</author>
<author><name sortKey="Lee, N" uniqKey="Lee N">N Lee</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
<author><name sortKey="Sung, Jj" uniqKey="Sung J">JJ Sung</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, Hl" uniqKey="Chan H">HL Chan</name>
</author>
<author><name sortKey="Kwan, Ac" uniqKey="Kwan A">AC Kwan</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Lai, St" uniqKey="Lai S">ST Lai</name>
</author>
<author><name sortKey="Chan, Pk" uniqKey="Chan P">PK Chan</name>
</author>
<author><name sortKey="Leung, Wk" uniqKey="Leung W">WK Leung</name>
</author>
<author><name sortKey="Lee, N" uniqKey="Lee N">N Lee</name>
</author>
<author><name sortKey="Wu, A" uniqKey="Wu A">A Wu</name>
</author>
<author><name sortKey="Sung, Jj" uniqKey="Sung J">JJ Sung</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chau, Tn" uniqKey="Chau T">TN Chau</name>
</author>
<author><name sortKey="Lee, Kc" uniqKey="Lee K">KC Lee</name>
</author>
<author><name sortKey="Yao, H" uniqKey="Yao H">H Yao</name>
</author>
<author><name sortKey="Tsang, Ty" uniqKey="Tsang T">TY Tsang</name>
</author>
<author><name sortKey="Chow, Tc" uniqKey="Chow T">TC Chow</name>
</author>
<author><name sortKey="Yeung, Yc" uniqKey="Yeung Y">YC Yeung</name>
</author>
<author><name sortKey="Choi, Kw" uniqKey="Choi K">KW Choi</name>
</author>
<author><name sortKey="Tso, Yk" uniqKey="Tso Y">YK Tso</name>
</author>
<author><name sortKey="Lau, T" uniqKey="Lau T">T Lau</name>
</author>
<author><name sortKey="Lai, St" uniqKey="Lai S">ST Lai</name>
</author>
<author><name sortKey="Lai, Cl" uniqKey="Lai C">CL Lai</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wei, L" uniqKey="Wei L">L Wei</name>
</author>
<author><name sortKey="Sun, S" uniqKey="Sun S">S Sun</name>
</author>
<author><name sortKey="Xu, Ch" uniqKey="Xu C">CH Xu</name>
</author>
<author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name>
</author>
<author><name sortKey="Xu, Y" uniqKey="Xu Y">Y Xu</name>
</author>
<author><name sortKey="Zhu, H" uniqKey="Zhu H">H Zhu</name>
</author>
<author><name sortKey="Peh, Sc" uniqKey="Peh S">SC Peh</name>
</author>
<author><name sortKey="Korteweg, C" uniqKey="Korteweg C">C Korteweg</name>
</author>
<author><name sortKey="Mcnutt, Ma" uniqKey="Mcnutt M">MA McNutt</name>
</author>
<author><name sortKey="Gu, J" uniqKey="Gu J">J Gu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Leung, Tw" uniqKey="Leung T">TW Leung</name>
</author>
<author><name sortKey="Wong, Ks" uniqKey="Wong K">KS Wong</name>
</author>
<author><name sortKey="Hui, Ac" uniqKey="Hui A">AC Hui</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Lai, St" uniqKey="Lai S">ST Lai</name>
</author>
<author><name sortKey="Ng, Wf" uniqKey="Ng W">WF Ng</name>
</author>
<author><name sortKey="Ng, Hk" uniqKey="Ng H">HK Ng</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Li, W" uniqKey="Li W">W Li</name>
</author>
<author><name sortKey="Moore, Mj" uniqKey="Moore M">MJ Moore</name>
</author>
<author><name sortKey="Vasilieva, N" uniqKey="Vasilieva N">N Vasilieva</name>
</author>
<author><name sortKey="Sui, J" uniqKey="Sui J">J Sui</name>
</author>
<author><name sortKey="Wong, Sk" uniqKey="Wong S">SK Wong</name>
</author>
<author><name sortKey="Berne, Ma" uniqKey="Berne M">MA Berne</name>
</author>
<author><name sortKey="Somasundaran, M" uniqKey="Somasundaran M">M Somasundaran</name>
</author>
<author><name sortKey="Sullivan, Jl" uniqKey="Sullivan J">JL Sullivan</name>
</author>
<author><name sortKey="Luzuriaga, K" uniqKey="Luzuriaga K">K Luzuriaga</name>
</author>
<author><name sortKey="Greenough, Tc" uniqKey="Greenough T">TC Greenough</name>
</author>
<author><name sortKey="Choe, H" uniqKey="Choe H">H Choe</name>
</author>
<author><name sortKey="Farzan, M" uniqKey="Farzan M">M Farzan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sims, Ac" uniqKey="Sims A">AC Sims</name>
</author>
<author><name sortKey="Baric, Rs" uniqKey="Baric R">RS Baric</name>
</author>
<author><name sortKey="Yount, B" uniqKey="Yount B">B Yount</name>
</author>
<author><name sortKey="Burkett, Se" uniqKey="Burkett S">SE Burkett</name>
</author>
<author><name sortKey="Collins, Pl" uniqKey="Collins P">PL Collins</name>
</author>
<author><name sortKey="Pickles, Rj" uniqKey="Pickles R">RJ Pickles</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hamming, I" uniqKey="Hamming I">I Hamming</name>
</author>
<author><name sortKey="Timens, W" uniqKey="Timens W">W Timens</name>
</author>
<author><name sortKey="Bulthuis, Mlc" uniqKey="Bulthuis M">MLC Bulthuis</name>
</author>
<author><name sortKey="Lely, At" uniqKey="Lely A">AT Lely</name>
</author>
<author><name sortKey="Navis, Gj" uniqKey="Navis G">GJ Navis</name>
</author>
<author><name sortKey="Goor, Hv" uniqKey="Goor H">HV Goor</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ren, X" uniqKey="Ren X">X Ren</name>
</author>
<author><name sortKey="Glende, J" uniqKey="Glende J">J Glende</name>
</author>
<author><name sortKey="Al Falah, M" uniqKey="Al Falah M">M Al-Falah</name>
</author>
<author><name sortKey="De Vries, V" uniqKey="De Vries V">V de Vries</name>
</author>
<author><name sortKey="Schwegmann Wessels, C" uniqKey="Schwegmann Wessels C">C Schwegmann-Wessels</name>
</author>
<author><name sortKey="Qu, X" uniqKey="Qu X">X Qu</name>
</author>
<author><name sortKey="Tan, L" uniqKey="Tan L">L Tan</name>
</author>
<author><name sortKey="Tschernig, T" uniqKey="Tschernig T">T Tschernig</name>
</author>
<author><name sortKey="Deng, H" uniqKey="Deng H">H Deng</name>
</author>
<author><name sortKey="Naim, Hy" uniqKey="Naim H">HY Naim</name>
</author>
<author><name sortKey="Herrler, G" uniqKey="Herrler G">G Herrler</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, Pk" uniqKey="Chan P">PK Chan</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Lo, Aw" uniqKey="Lo A">AW Lo</name>
</author>
<author><name sortKey="Cheung, Jl" uniqKey="Cheung J">JL Cheung</name>
</author>
<author><name sortKey="Chu, I" uniqKey="Chu I">I Chu</name>
</author>
<author><name sortKey="Au, Fw" uniqKey="Au F">FW Au</name>
</author>
<author><name sortKey="Tong, Jh" uniqKey="Tong J">JH Tong</name>
</author>
<author><name sortKey="Tam, Js" uniqKey="Tam J">JS Tam</name>
</author>
<author><name sortKey="Sung, Jj" uniqKey="Sung J">JJ Sung</name>
</author>
<author><name sortKey="Ng, Hk" uniqKey="Ng H">HK Ng</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jia, Hp" uniqKey="Jia H">HP Jia</name>
</author>
<author><name sortKey="Look, Dc" uniqKey="Look D">DC Look</name>
</author>
<author><name sortKey="Shi, L" uniqKey="Shi L">L Shi</name>
</author>
<author><name sortKey="Hickey, M" uniqKey="Hickey M">M Hickey</name>
</author>
<author><name sortKey="Pewe, L" uniqKey="Pewe L">L Pewe</name>
</author>
<author><name sortKey="Netland, J" uniqKey="Netland J">J Netland</name>
</author>
<author><name sortKey="Farzan, M" uniqKey="Farzan M">M Farzan</name>
</author>
<author><name sortKey="Wohlford Lenane, C" uniqKey="Wohlford Lenane C">C Wohlford-Lenane</name>
</author>
<author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name>
</author>
<author><name sortKey="Mccray, Pb" uniqKey="Mccray P">PB McCray</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Huang, Ic" uniqKey="Huang I">IC Huang</name>
</author>
<author><name sortKey="Bosch, Bj" uniqKey="Bosch B">BJ Bosch</name>
</author>
<author><name sortKey="Li, F" uniqKey="Li F">F Li</name>
</author>
<author><name sortKey="Li, W" uniqKey="Li W">W Li</name>
</author>
<author><name sortKey="Lee, Kh" uniqKey="Lee K">KH Lee</name>
</author>
<author><name sortKey="Ghiran, S" uniqKey="Ghiran S">S Ghiran</name>
</author>
<author><name sortKey="Vasilieva, N" uniqKey="Vasilieva N">N Vasilieva</name>
</author>
<author><name sortKey="Dermody, Ts" uniqKey="Dermody T">TS Dermody</name>
</author>
<author><name sortKey="Harrison, Sc" uniqKey="Harrison S">SC Harrison</name>
</author>
<author><name sortKey="Dormitzer, Pr" uniqKey="Dormitzer P">PR Dormitzer</name>
</author>
<author><name sortKey="Farzan, M" uniqKey="Farzan M">M Farzan</name>
</author>
<author><name sortKey="Rottier, Pj" uniqKey="Rottier P">PJ Rottier</name>
</author>
<author><name sortKey="Choe, H" uniqKey="Choe H">H Choe</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Simmons, G" uniqKey="Simmons G">G Simmons</name>
</author>
<author><name sortKey="Gosalia, Dn" uniqKey="Gosalia D">DN Gosalia</name>
</author>
<author><name sortKey="Rennekamp, Aj" uniqKey="Rennekamp A">AJ Rennekamp</name>
</author>
<author><name sortKey="Reeves, Jd" uniqKey="Reeves J">JD Reeves</name>
</author>
<author><name sortKey="Diamond, Sl" uniqKey="Diamond S">SL Diamond</name>
</author>
<author><name sortKey="Bates, P" uniqKey="Bates P">P Bates</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jeffers, Sa" uniqKey="Jeffers S">SA Jeffers</name>
</author>
<author><name sortKey="Tusell, Sm" uniqKey="Tusell S">SM Tusell</name>
</author>
<author><name sortKey="Gillim Ross, L" uniqKey="Gillim Ross L">L Gillim-Ross</name>
</author>
<author><name sortKey="Hemmila, Em" uniqKey="Hemmila E">EM Hemmila</name>
</author>
<author><name sortKey="Achenbach, Je" uniqKey="Achenbach J">JE Achenbach</name>
</author>
<author><name sortKey="Babcock, Gj" uniqKey="Babcock G">GJ Babcock</name>
</author>
<author><name sortKey="Thomas, Wd" uniqKey="Thomas W">WD Thomas</name>
</author>
<author><name sortKey="Thackray, Lb" uniqKey="Thackray L">LB Thackray</name>
</author>
<author><name sortKey="Young, Md" uniqKey="Young M">MD Young</name>
</author>
<author><name sortKey="Mason, Rj" uniqKey="Mason R">RJ Mason</name>
</author>
<author><name sortKey="Ambrosino, Dm" uniqKey="Ambrosino D">DM Ambrosino</name>
</author>
<author><name sortKey="Wentworth, De" uniqKey="Wentworth D">DE Wentworth</name>
</author>
<author><name sortKey="Demartini, Jc" uniqKey="Demartini J">JC Demartini</name>
</author>
<author><name sortKey="Holmes, Kv" uniqKey="Holmes K">KV Holmes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Marzi, A" uniqKey="Marzi A">A Marzi</name>
</author>
<author><name sortKey="Gramberg, T" uniqKey="Gramberg T">T Gramberg</name>
</author>
<author><name sortKey="Simmons, G" uniqKey="Simmons G">G Simmons</name>
</author>
<author><name sortKey="Moller, P" uniqKey="Moller P">P Moller</name>
</author>
<author><name sortKey="Rennekamp, Aj" uniqKey="Rennekamp A">AJ Rennekamp</name>
</author>
<author><name sortKey="Krumbiegel, M" uniqKey="Krumbiegel M">M Krumbiegel</name>
</author>
<author><name sortKey="Geier, M" uniqKey="Geier M">M Geier</name>
</author>
<author><name sortKey="Eisemann, J" uniqKey="Eisemann J">J Eisemann</name>
</author>
<author><name sortKey="Turza, N" uniqKey="Turza N">N Turza</name>
</author>
<author><name sortKey="Saunier, B" uniqKey="Saunier B">B Saunier</name>
</author>
<author><name sortKey="Steinkasserer, A" uniqKey="Steinkasserer A">A Steinkasserer</name>
</author>
<author><name sortKey="Becker, S" uniqKey="Becker S">S Becker</name>
</author>
<author><name sortKey="Bates, P" uniqKey="Bates P">P Bates</name>
</author>
<author><name sortKey="Hofmann, H" uniqKey="Hofmann H">H Hofmann</name>
</author>
<author><name sortKey="Pohlmann, S" uniqKey="Pohlmann S">S Pohlmann</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bashirova, Aa" uniqKey="Bashirova A">AA Bashirova</name>
</author>
<author><name sortKey="Geijtenbeek, Tb" uniqKey="Geijtenbeek T">TB Geijtenbeek</name>
</author>
<author><name sortKey="Van Duijnhoven, Gc" uniqKey="Van Duijnhoven G">GC van Duijnhoven</name>
</author>
<author><name sortKey="Van Vliet, Sj" uniqKey="Van Vliet S">SJ van Vliet</name>
</author>
<author><name sortKey="Eilering, Jb" uniqKey="Eilering J">JB Eilering</name>
</author>
<author><name sortKey="Martin, Mp" uniqKey="Martin M">MP Martin</name>
</author>
<author><name sortKey="Wu, L" uniqKey="Wu L">L Wu</name>
</author>
<author><name sortKey="Martin, Td" uniqKey="Martin T">TD Martin</name>
</author>
<author><name sortKey="Viebig, N" uniqKey="Viebig N">N Viebig</name>
</author>
<author><name sortKey="Knolle, Pa" uniqKey="Knolle P">PA Knolle</name>
</author>
<author><name sortKey="Kewalramani, Vn" uniqKey="Kewalramani V">VN KewalRamani</name>
</author>
<author><name sortKey="Van Kooyk, Y" uniqKey="Van Kooyk Y">Y van Kooyk</name>
</author>
<author><name sortKey="Carrington, M" uniqKey="Carrington M">M Carrington</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Soilleux, Ej" uniqKey="Soilleux E">EJ Soilleux</name>
</author>
<author><name sortKey="Morris, Ls" uniqKey="Morris L">LS Morris</name>
</author>
<author><name sortKey="Leslie, G" uniqKey="Leslie G">G Leslie</name>
</author>
<author><name sortKey="Chehimi, J" uniqKey="Chehimi J">J Chehimi</name>
</author>
<author><name sortKey="Luo, Q" uniqKey="Luo Q">Q Luo</name>
</author>
<author><name sortKey="Levroney, E" uniqKey="Levroney E">E Levroney</name>
</author>
<author><name sortKey="Trowsdale, J" uniqKey="Trowsdale J">J Trowsdale</name>
</author>
<author><name sortKey="Montaner, Lj" uniqKey="Montaner L">LJ Montaner</name>
</author>
<author><name sortKey="Doms, Rw" uniqKey="Doms R">RW Doms</name>
</author>
<author><name sortKey="Weissman, D" uniqKey="Weissman D">D Weissman</name>
</author>
<author><name sortKey="Coleman, N" uniqKey="Coleman N">N Coleman</name>
</author>
<author><name sortKey="Lee, B" uniqKey="Lee B">B Lee</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yang, Zy" uniqKey="Yang Z">ZY Yang</name>
</author>
<author><name sortKey="Huang, Y" uniqKey="Huang Y">Y Huang</name>
</author>
<author><name sortKey="Ganesh, L" uniqKey="Ganesh L">L Ganesh</name>
</author>
<author><name sortKey="Leung, K" uniqKey="Leung K">K Leung</name>
</author>
<author><name sortKey="Kong, Wp" uniqKey="Kong W">WP Kong</name>
</author>
<author><name sortKey="Schwartz, O" uniqKey="Schwartz O">O Schwartz</name>
</author>
<author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K Subbarao</name>
</author>
<author><name sortKey="Nabel, Gj" uniqKey="Nabel G">GJ Nabel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Imai, Y" uniqKey="Imai Y">Y Imai</name>
</author>
<author><name sortKey="Kuba, K" uniqKey="Kuba K">K Kuba</name>
</author>
<author><name sortKey="Rao, S" uniqKey="Rao S">S Rao</name>
</author>
<author><name sortKey="Huan, Y" uniqKey="Huan Y">Y Huan</name>
</author>
<author><name sortKey="Guo, F" uniqKey="Guo F">F Guo</name>
</author>
<author><name sortKey="Guan, B" uniqKey="Guan B">B Guan</name>
</author>
<author><name sortKey="Yang, P" uniqKey="Yang P">P Yang</name>
</author>
<author><name sortKey="Sarao, R" uniqKey="Sarao R">R Sarao</name>
</author>
<author><name sortKey="Wada, T" uniqKey="Wada T">T Wada</name>
</author>
<author><name sortKey="Leong Poi, H" uniqKey="Leong Poi H">H Leong-Poi</name>
</author>
<author><name sortKey="Crackower, Ma" uniqKey="Crackower M">MA Crackower</name>
</author>
<author><name sortKey="Fukamizu, A" uniqKey="Fukamizu A">A Fukamizu</name>
</author>
<author><name sortKey="Hui, Cc" uniqKey="Hui C">CC Hui</name>
</author>
<author><name sortKey="Hein, L" uniqKey="Hein L">L Hein</name>
</author>
<author><name sortKey="Uhlig, S" uniqKey="Uhlig S">S Uhlig</name>
</author>
<author><name sortKey="Slutsky, As" uniqKey="Slutsky A">AS Slutsky</name>
</author>
<author><name sortKey="Jiang, C" uniqKey="Jiang C">C Jiang</name>
</author>
<author><name sortKey="Penninger, Jm" uniqKey="Penninger J">JM Penninger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kuba, K" uniqKey="Kuba K">K Kuba</name>
</author>
<author><name sortKey="Imai, Y" uniqKey="Imai Y">Y Imai</name>
</author>
<author><name sortKey="Rao, S" uniqKey="Rao S">S Rao</name>
</author>
<author><name sortKey="Gao, H" uniqKey="Gao H">H Gao</name>
</author>
<author><name sortKey="Guo, F" uniqKey="Guo F">F Guo</name>
</author>
<author><name sortKey="Guan, B" uniqKey="Guan B">B Guan</name>
</author>
<author><name sortKey="Huan, Y" uniqKey="Huan Y">Y Huan</name>
</author>
<author><name sortKey="Yang, P" uniqKey="Yang P">P Yang</name>
</author>
<author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name>
</author>
<author><name sortKey="Deng, W" uniqKey="Deng W">W Deng</name>
</author>
<author><name sortKey="Bao, L" uniqKey="Bao L">L Bao</name>
</author>
<author><name sortKey="Zhang, B" uniqKey="Zhang B">B Zhang</name>
</author>
<author><name sortKey="Liu, G" uniqKey="Liu G">G Liu</name>
</author>
<author><name sortKey="Wang, Z" uniqKey="Wang Z">Z Wang</name>
</author>
<author><name sortKey="Chappell, M" uniqKey="Chappell M">M Chappell</name>
</author>
<author><name sortKey="Liu, Y" uniqKey="Liu Y">Y Liu</name>
</author>
<author><name sortKey="Zheng, D" uniqKey="Zheng D">D Zheng</name>
</author>
<author><name sortKey="Leibbrandt, A" uniqKey="Leibbrandt A">A Leibbrandt</name>
</author>
<author><name sortKey="Wada, T" uniqKey="Wada T">T Wada</name>
</author>
<author><name sortKey="Slutsky, As" uniqKey="Slutsky A">AS Slutsky</name>
</author>
<author><name sortKey="Liu, D" uniqKey="Liu D">D Liu</name>
</author>
<author><name sortKey="Qin, C" uniqKey="Qin C">C Qin</name>
</author>
<author><name sortKey="Jiang, C" uniqKey="Jiang C">C Jiang</name>
</author>
<author><name sortKey="Penninger, Jm" uniqKey="Penninger J">JM Penninger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yan, H" uniqKey="Yan H">H Yan</name>
</author>
<author><name sortKey="Xiao, G" uniqKey="Xiao G">G Xiao</name>
</author>
<author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name>
</author>
<author><name sortKey="Hu, Y" uniqKey="Hu Y">Y Hu</name>
</author>
<author><name sortKey="Yuan, F" uniqKey="Yuan F">F Yuan</name>
</author>
<author><name sortKey="Cole, Dk" uniqKey="Cole D">DK Cole</name>
</author>
<author><name sortKey="Zheng, C" uniqKey="Zheng C">C Zheng</name>
</author>
<author><name sortKey="Gao, Gf" uniqKey="Gao G">GF Gao</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tan, Yj" uniqKey="Tan Y">YJ Tan</name>
</author>
<author><name sortKey="Fielding, Bc" uniqKey="Fielding B">BC Fielding</name>
</author>
<author><name sortKey="Goh, Py" uniqKey="Goh P">PY Goh</name>
</author>
<author><name sortKey="Shen, S" uniqKey="Shen S">S Shen</name>
</author>
<author><name sortKey="Tan, Th" uniqKey="Tan T">TH Tan</name>
</author>
<author><name sortKey="Lim, Sg" uniqKey="Lim S">SG Lim</name>
</author>
<author><name sortKey="Hong, W" uniqKey="Hong W">W Hong</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Law, Pt" uniqKey="Law P">PT Law</name>
</author>
<author><name sortKey="Wong, Ch" uniqKey="Wong C">CH Wong</name>
</author>
<author><name sortKey="Au, Tc" uniqKey="Au T">TC Au</name>
</author>
<author><name sortKey="Chuck, Cp" uniqKey="Chuck C">CP Chuck</name>
</author>
<author><name sortKey="Kong, Sk" uniqKey="Kong S">SK Kong</name>
</author>
<author><name sortKey="Chan, Pk" uniqKey="Chan P">PK Chan</name>
</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Lo, Aw" uniqKey="Lo A">AW Lo</name>
</author>
<author><name sortKey="Chan, Jy" uniqKey="Chan J">JY Chan</name>
</author>
<author><name sortKey="Suen, Yk" uniqKey="Suen Y">YK Suen</name>
</author>
<author><name sortKey="Chan, Hy" uniqKey="Chan H">HY Chan</name>
</author>
<author><name sortKey="Fung, Kp" uniqKey="Fung K">KP Fung</name>
</author>
<author><name sortKey="Waye, Mm" uniqKey="Waye M">MM Waye</name>
</author>
<author><name sortKey="Sung, Jj" uniqKey="Sung J">JJ Sung</name>
</author>
<author><name sortKey="Lo, Ym" uniqKey="Lo Y">YM Lo</name>
</author>
<author><name sortKey="Tsui, Sk" uniqKey="Tsui S">SK Tsui</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y Yang</name>
</author>
<author><name sortKey="Xiong, Z" uniqKey="Xiong Z">Z Xiong</name>
</author>
<author><name sortKey="Zhang, S" uniqKey="Zhang S">S Zhang</name>
</author>
<author><name sortKey="Yan, Y" uniqKey="Yan Y">Y Yan</name>
</author>
<author><name sortKey="Nguyen, J" uniqKey="Nguyen J">J Nguyen</name>
</author>
<author><name sortKey="Ng, B" uniqKey="Ng B">B Ng</name>
</author>
<author><name sortKey="Lu, H" uniqKey="Lu H">H Lu</name>
</author>
<author><name sortKey="Brendese, J" uniqKey="Brendese J">J Brendese</name>
</author>
<author><name sortKey="Yang, F" uniqKey="Yang F">F Yang</name>
</author>
<author><name sortKey="Wang, H" uniqKey="Wang H">H Wang</name>
</author>
<author><name sortKey="Yang, Xf" uniqKey="Yang X">XF Yang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ng, Lf" uniqKey="Ng L">LF Ng</name>
</author>
<author><name sortKey="Hibberd, Ml" uniqKey="Hibberd M">ML Hibberd</name>
</author>
<author><name sortKey="Ooi, Ee" uniqKey="Ooi E">EE Ooi</name>
</author>
<author><name sortKey="Tang, Kf" uniqKey="Tang K">KF Tang</name>
</author>
<author><name sortKey="Neo, Sy" uniqKey="Neo S">SY Neo</name>
</author>
<author><name sortKey="Tan, J" uniqKey="Tan J">J Tan</name>
</author>
<author><name sortKey="Murthy, Kr" uniqKey="Murthy K">KR Murthy</name>
</author>
<author><name sortKey="Vega, Vb" uniqKey="Vega V">VB Vega</name>
</author>
<author><name sortKey="Chia, Jm" uniqKey="Chia J">JM Chia</name>
</author>
<author><name sortKey="Liu, Et" uniqKey="Liu E">ET Liu</name>
</author>
<author><name sortKey="Ren, Ec" uniqKey="Ren E">EC Ren</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Law, Hk" uniqKey="Law H">HK Law</name>
</author>
<author><name sortKey="Cheung, Cy" uniqKey="Cheung C">CY Cheung</name>
</author>
<author><name sortKey="Ng, Hy" uniqKey="Ng H">HY Ng</name>
</author>
<author><name sortKey="Sia, Sf" uniqKey="Sia S">SF Sia</name>
</author>
<author><name sortKey="Chan, Yo" uniqKey="Chan Y">YO Chan</name>
</author>
<author><name sortKey="Luk, W" uniqKey="Luk W">W Luk</name>
</author>
<author><name sortKey="Nicholls, Jm" uniqKey="Nicholls J">JM Nicholls</name>
</author>
<author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS Peiris</name>
</author>
<author><name sortKey="Lau, Yl" uniqKey="Lau Y">YL Lau</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cheung, Cy" uniqKey="Cheung C">CY Cheung</name>
</author>
<author><name sortKey="Poon, Ll" uniqKey="Poon L">LL Poon</name>
</author>
<author><name sortKey="Ng, Ih" uniqKey="Ng I">IH Ng</name>
</author>
<author><name sortKey="Luk, W" uniqKey="Luk W">W Luk</name>
</author>
<author><name sortKey="Sia, Sf" uniqKey="Sia S">SF Sia</name>
</author>
<author><name sortKey="Wu, Mh" uniqKey="Wu M">MH Wu</name>
</author>
<author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
<author><name sortKey="Gordon, S" uniqKey="Gordon S">S Gordon</name>
</author>
<author><name sortKey="Guan, Y" uniqKey="Guan Y">Y Guan</name>
</author>
<author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS Peiris</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Li, L" uniqKey="Li L">L Li</name>
</author>
<author><name sortKey="Wo, J" uniqKey="Wo J">J Wo</name>
</author>
<author><name sortKey="Shao, J" uniqKey="Shao J">J Shao</name>
</author>
<author><name sortKey="Zhu, H" uniqKey="Zhu H">H Zhu</name>
</author>
<author><name sortKey="Wu, N" uniqKey="Wu N">N Wu</name>
</author>
<author><name sortKey="Li, M" uniqKey="Li M">M Li</name>
</author>
<author><name sortKey="Yao, H" uniqKey="Yao H">H Yao</name>
</author>
<author><name sortKey="Hu, M" uniqKey="Hu M">M Hu</name>
</author>
<author><name sortKey="Dennin, Rh" uniqKey="Dennin R">RH Dennin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schneider Schaulies, S" uniqKey="Schneider Schaulies S">S Schneider-Schaulies</name>
</author>
<author><name sortKey="Niewiesk, S" uniqKey="Niewiesk S">S Niewiesk</name>
</author>
<author><name sortKey="Schneider Schaulies, J" uniqKey="Schneider Schaulies J">J Schneider-Schaulies</name>
</author>
<author><name sortKey="Ter Meulen, V" uniqKey="Ter Meulen V">V ter Meulen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Geisbert, Tw" uniqKey="Geisbert T">TW Geisbert</name>
</author>
<author><name sortKey="Jahrling, Pb" uniqKey="Jahrling P">PB Jahrling</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Openshaw, Pj" uniqKey="Openshaw P">PJ Openshaw</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lee, Ch" uniqKey="Lee C">CH Lee</name>
</author>
<author><name sortKey="Chen, Rf" uniqKey="Chen R">RF Chen</name>
</author>
<author><name sortKey="Liu, Jw" uniqKey="Liu J">JW Liu</name>
</author>
<author><name sortKey="Yeh, Wt" uniqKey="Yeh W">WT Yeh</name>
</author>
<author><name sortKey="Chang, Jc" uniqKey="Chang J">JC Chang</name>
</author>
<author><name sortKey="Liu, Pm" uniqKey="Liu P">PM Liu</name>
</author>
<author><name sortKey="Eng, Hl" uniqKey="Eng H">HL Eng</name>
</author>
<author><name sortKey="Lin, Mc" uniqKey="Lin M">MC Lin</name>
</author>
<author><name sortKey="Yang, Kd" uniqKey="Yang K">KD Yang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Huang, Kj" uniqKey="Huang K">KJ Huang</name>
</author>
<author><name sortKey="Su, Ij" uniqKey="Su I">IJ Su</name>
</author>
<author><name sortKey="Theron, M" uniqKey="Theron M">M Theron</name>
</author>
<author><name sortKey="Wu, Yc" uniqKey="Wu Y">YC Wu</name>
</author>
<author><name sortKey="Lai, Sk" uniqKey="Lai S">SK Lai</name>
</author>
<author><name sortKey="Liu, Cc" uniqKey="Liu C">CC Liu</name>
</author>
<author><name sortKey="Lei, Hy" uniqKey="Lei H">HY Lei</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wong, Ck" uniqKey="Wong C">CK Wong</name>
</author>
<author><name sortKey="Lam, Cw" uniqKey="Lam C">CW Lam</name>
</author>
<author><name sortKey="Wu, Ak" uniqKey="Wu A">AK Wu</name>
</author>
<author><name sortKey="Ip, Wk" uniqKey="Ip W">WK Ip</name>
</author>
<author><name sortKey="Lee, Nl" uniqKey="Lee N">NL Lee</name>
</author>
<author><name sortKey="Chan, Ih" uniqKey="Chan I">IH Chan</name>
</author>
<author><name sortKey="Lit, Lc" uniqKey="Lit L">LC Lit</name>
</author>
<author><name sortKey="Hui, Ds" uniqKey="Hui D">DS Hui</name>
</author>
<author><name sortKey="Chan, Mh" uniqKey="Chan M">MH Chan</name>
</author>
<author><name sortKey="Chung, Ss" uniqKey="Chung S">SS Chung</name>
</author>
<author><name sortKey="Sung, Jj" uniqKey="Sung J">JJ Sung</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Spiegel, M" uniqKey="Spiegel M">M Spiegel</name>
</author>
<author><name sortKey="Pichlmair, A" uniqKey="Pichlmair A">A Pichlmair</name>
</author>
<author><name sortKey="Martinez Sobrido, L" uniqKey="Martinez Sobrido L">L Martinez-Sobrido</name>
</author>
<author><name sortKey="Cros, J" uniqKey="Cros J">J Cros</name>
</author>
<author><name sortKey="Garcia Sastre, A" uniqKey="Garcia Sastre A">A Garcia-Sastre</name>
</author>
<author><name sortKey="Haller, O" uniqKey="Haller O">O Haller</name>
</author>
<author><name sortKey="Weber, F" uniqKey="Weber F">F Weber</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tseng, Ct" uniqKey="Tseng C">CT Tseng</name>
</author>
<author><name sortKey="Perrone, La" uniqKey="Perrone L">LA Perrone</name>
</author>
<author><name sortKey="Zhu, H" uniqKey="Zhu H">H Zhu</name>
</author>
<author><name sortKey="Makino, S" uniqKey="Makino S">S Makino</name>
</author>
<author><name sortKey="Peters, Cj" uniqKey="Peters C">CJ Peters</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Medzhitov, R" uniqKey="Medzhitov R">R Medzhitov</name>
</author>
<author><name sortKey="Janeway, C" uniqKey="Janeway C">C Janeway</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ip, Wk" uniqKey="Ip W">WK Ip</name>
</author>
<author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name>
</author>
<author><name sortKey="Law, Hk" uniqKey="Law H">HK Law</name>
</author>
<author><name sortKey="Tso, Gh" uniqKey="Tso G">GH Tso</name>
</author>
<author><name sortKey="Kong, Ek" uniqKey="Kong E">EK Kong</name>
</author>
<author><name sortKey="Wong, Wh" uniqKey="Wong W">WH Wong</name>
</author>
<author><name sortKey="To, Yf" uniqKey="To Y">YF To</name>
</author>
<author><name sortKey="Yung, Rw" uniqKey="Yung R">RW Yung</name>
</author>
<author><name sortKey="Chow, Ey" uniqKey="Chow E">EY Chow</name>
</author>
<author><name sortKey="Au, Kl" uniqKey="Au K">KL Au</name>
</author>
<author><name sortKey="Chan, Ey" uniqKey="Chan E">EY Chan</name>
</author>
<author><name sortKey="Lim, W" uniqKey="Lim W">W Lim</name>
</author>
<author><name sortKey="Jensenius, Jc" uniqKey="Jensenius J">JC Jensenius</name>
</author>
<author><name sortKey="Turner, Mw" uniqKey="Turner M">MW Turner</name>
</author>
<author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS Peiris</name>
</author>
<author><name sortKey="Lau, Yl" uniqKey="Lau Y">YL Lau</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lin, Ys" uniqKey="Lin Y">YS Lin</name>
</author>
<author><name sortKey="Lin, Cf" uniqKey="Lin C">CF Lin</name>
</author>
<author><name sortKey="Fang, Yt" uniqKey="Fang Y">YT Fang</name>
</author>
<author><name sortKey="Kuo, Ym" uniqKey="Kuo Y">YM Kuo</name>
</author>
<author><name sortKey="Liao, Pc" uniqKey="Liao P">PC Liao</name>
</author>
<author><name sortKey="Yeh, Tm" uniqKey="Yeh T">TM Yeh</name>
</author>
<author><name sortKey="Hwa, Ky" uniqKey="Hwa K">KY Hwa</name>
</author>
<author><name sortKey="Shieh, Cc" uniqKey="Shieh C">CC Shieh</name>
</author>
<author><name sortKey="Yen, Jh" uniqKey="Yen J">JH Yen</name>
</author>
<author><name sortKey="Wang, Hj" uniqKey="Wang H">HJ Wang</name>
</author>
<author><name sortKey="Su, Ij" uniqKey="Su I">IJ Su</name>
</author>
<author><name sortKey="Lei, Hy" uniqKey="Lei H">HY Lei</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yang, Yh" uniqKey="Yang Y">YH Yang</name>
</author>
<author><name sortKey="Huang, Yh" uniqKey="Huang Y">YH Huang</name>
</author>
<author><name sortKey="Chuang, Yh" uniqKey="Chuang Y">YH Chuang</name>
</author>
<author><name sortKey="Peng, Cm" uniqKey="Peng C">CM Peng</name>
</author>
<author><name sortKey="Wang, Lc" uniqKey="Wang L">LC Wang</name>
</author>
<author><name sortKey="Lin, Yt" uniqKey="Lin Y">YT Lin</name>
</author>
<author><name sortKey="Chiang, Bl" uniqKey="Chiang B">BL Chiang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Leung, Gm" uniqKey="Leung G">GM Leung</name>
</author>
<author><name sortKey="Hedley, Aj" uniqKey="Hedley A">AJ Hedley</name>
</author>
<author><name sortKey="Ho, Lm" uniqKey="Ho L">LM Ho</name>
</author>
<author><name sortKey="Chau, P" uniqKey="Chau P">P Chau</name>
</author>
<author><name sortKey="Wong, Io" uniqKey="Wong I">IO Wong</name>
</author>
<author><name sortKey="Thach, Tq" uniqKey="Thach T">TQ Thach</name>
</author>
<author><name sortKey="Ghani, Ac" uniqKey="Ghani A">AC Ghani</name>
</author>
<author><name sortKey="Donnelly, Ca" uniqKey="Donnelly C">CA Donnelly</name>
</author>
<author><name sortKey="Fraser, C" uniqKey="Fraser C">C Fraser</name>
</author>
<author><name sortKey="Riley, S" uniqKey="Riley S">S Riley</name>
</author>
<author><name sortKey="Ferguson, Nm" uniqKey="Ferguson N">NM Ferguson</name>
</author>
<author><name sortKey="Anderson, Rm" uniqKey="Anderson R">RM Anderson</name>
</author>
<author><name sortKey="Tsang, T" uniqKey="Tsang T">T Tsang</name>
</author>
<author><name sortKey="Leung, Py" uniqKey="Leung P">PY Leung</name>
</author>
<author><name sortKey="Wong, V" uniqKey="Wong V">V Wong</name>
</author>
<author><name sortKey="Chan, Jc" uniqKey="Chan J">JC Chan</name>
</author>
<author><name sortKey="Tsui, E" uniqKey="Tsui E">E Tsui</name>
</author>
<author><name sortKey="Lo, Sv" uniqKey="Lo S">SV Lo</name>
</author>
<author><name sortKey="Lam, Th" uniqKey="Lam T">TH Lam</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Booth, Cm" uniqKey="Booth C">CM Booth</name>
</author>
<author><name sortKey="Matukas, Lm" uniqKey="Matukas L">LM Matukas</name>
</author>
<author><name sortKey="Tomlinson, Ga" uniqKey="Tomlinson G">GA Tomlinson</name>
</author>
<author><name sortKey="Rachlis, Ar" uniqKey="Rachlis A">AR Rachlis</name>
</author>
<author><name sortKey="Rose, Db" uniqKey="Rose D">DB Rose</name>
</author>
<author><name sortKey="Dwosh, Ha" uniqKey="Dwosh H">HA Dwosh</name>
</author>
<author><name sortKey="Walmsley, Sl" uniqKey="Walmsley S">SL Walmsley</name>
</author>
<author><name sortKey="Mazzulli, T" uniqKey="Mazzulli T">T Mazzulli</name>
</author>
<author><name sortKey="Avendano, M" uniqKey="Avendano M">M Avendano</name>
</author>
<author><name sortKey="Derkach, P" uniqKey="Derkach P">P Derkach</name>
</author>
<author><name sortKey="Ephtimios, Ie" uniqKey="Ephtimios I">IE Ephtimios</name>
</author>
<author><name sortKey="Kitai, I" uniqKey="Kitai I">I Kitai</name>
</author>
<author><name sortKey="Mederski, Bd" uniqKey="Mederski B">BD Mederski</name>
</author>
<author><name sortKey="Shadowitz, Sb" uniqKey="Shadowitz S">SB Shadowitz</name>
</author>
<author><name sortKey="Gold, Wl" uniqKey="Gold W">WL Gold</name>
</author>
<author><name sortKey="Hawryluck, La" uniqKey="Hawryluck L">LA Hawryluck</name>
</author>
<author><name sortKey="Rea, E" uniqKey="Rea E">E Rea</name>
</author>
<author><name sortKey="Chenkin, Js" uniqKey="Chenkin J">JS Chenkin</name>
</author>
<author><name sortKey="Cescon, Dw" uniqKey="Cescon D">DW Cescon</name>
</author>
<author><name sortKey="Poutanen, Sm" uniqKey="Poutanen S">SM Poutanen</name>
</author>
<author><name sortKey="Detsky, As" uniqKey="Detsky A">AS Detsky</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zou, Z" uniqKey="Zou Z">Z Zou</name>
</author>
<author><name sortKey="Yang, Y" uniqKey="Yang Y">Y Yang</name>
</author>
<author><name sortKey="Chen, J" uniqKey="Chen J">J Chen</name>
</author>
<author><name sortKey="Xin, S" uniqKey="Xin S">S Xin</name>
</author>
<author><name sortKey="Zhang, W" uniqKey="Zhang W">W Zhang</name>
</author>
<author><name sortKey="Zhou, X" uniqKey="Zhou X">X Zhou</name>
</author>
<author><name sortKey="Mao, Y" uniqKey="Mao Y">Y Mao</name>
</author>
<author><name sortKey="Hu, L" uniqKey="Hu L">L Hu</name>
</author>
<author><name sortKey="Liu, D" uniqKey="Liu D">D Liu</name>
</author>
<author><name sortKey="Chang, B" uniqKey="Chang B">B Chang</name>
</author>
<author><name sortKey="Chang, W" uniqKey="Chang W">W Chang</name>
</author>
<author><name sortKey="Liu, Y" uniqKey="Liu Y">Y Liu</name>
</author>
<author><name sortKey="Ma, X" uniqKey="Ma X">X Ma</name>
</author>
<author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name>
</author>
<author><name sortKey="Liu, X" uniqKey="Liu X">X Liu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, Jw" uniqKey="Chan J">JW Chan</name>
</author>
<author><name sortKey="Ng, Ck" uniqKey="Ng C">CK Ng</name>
</author>
<author><name sortKey="Chan, Yh" uniqKey="Chan Y">YH Chan</name>
</author>
<author><name sortKey="Mok, Ty" uniqKey="Mok T">TY Mok</name>
</author>
<author><name sortKey="Lee, S" uniqKey="Lee S">S Lee</name>
</author>
<author><name sortKey="Chu, Sy" uniqKey="Chu S">SY Chu</name>
</author>
<author><name sortKey="Law, Wl" uniqKey="Law W">WL Law</name>
</author>
<author><name sortKey="Lee, Mp" uniqKey="Lee M">MP Lee</name>
</author>
<author><name sortKey="Li, Pc" uniqKey="Li P">PC Li</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS Peiris</name>
</author>
<author><name sortKey="Chu, Cm" uniqKey="Chu C">CM Chu</name>
</author>
<author><name sortKey="Cheng, Vc" uniqKey="Cheng V">VC Cheng</name>
</author>
<author><name sortKey="Chan, Ks" uniqKey="Chan K">KS Chan</name>
</author>
<author><name sortKey="Hung, If" uniqKey="Hung I">IF Hung</name>
</author>
<author><name sortKey="Poon, Ll" uniqKey="Poon L">LL Poon</name>
</author>
<author><name sortKey="Law, Ki" uniqKey="Law K">KI Law</name>
</author>
<author><name sortKey="Tang, Bs" uniqKey="Tang B">BS Tang</name>
</author>
<author><name sortKey="Hon, Ty" uniqKey="Hon T">TY Hon</name>
</author>
<author><name sortKey="Chan, Cs" uniqKey="Chan C">CS Chan</name>
</author>
<author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name>
</author>
<author><name sortKey="Ng, Js" uniqKey="Ng J">JS Ng</name>
</author>
<author><name sortKey="Zheng, Bj" uniqKey="Zheng B">BJ Zheng</name>
</author>
<author><name sortKey="Ng, Wl" uniqKey="Ng W">WL Ng</name>
</author>
<author><name sortKey="Lai, Rw" uniqKey="Lai R">RW Lai</name>
</author>
<author><name sortKey="Guan, Y" uniqKey="Guan Y">Y Guan</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
<author><name sortKey="Hku Uch Sars Study Group" uniqKey="Hku Uch Sars Study Group">HKU/UCH SARS Study Group</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lin, M" uniqKey="Lin M">M Lin</name>
</author>
<author><name sortKey="Tseng, Hk" uniqKey="Tseng H">HK Tseng</name>
</author>
<author><name sortKey="Trejaut, Ja" uniqKey="Trejaut J">JA Trejaut</name>
</author>
<author><name sortKey="Lee, Hl" uniqKey="Lee H">HL Lee</name>
</author>
<author><name sortKey="Loo, Jh" uniqKey="Loo J">JH Loo</name>
</author>
<author><name sortKey="Chu, Cc" uniqKey="Chu C">CC Chu</name>
</author>
<author><name sortKey="Chen, Pj" uniqKey="Chen P">PJ Chen</name>
</author>
<author><name sortKey="Su, Yw" uniqKey="Su Y">YW Su</name>
</author>
<author><name sortKey="Lim, Kh" uniqKey="Lim K">KH Lim</name>
</author>
<author><name sortKey="Tsai, Zu" uniqKey="Tsai Z">ZU Tsai</name>
</author>
<author><name sortKey="Lin, Ry" uniqKey="Lin R">RY Lin</name>
</author>
<author><name sortKey="Lin, Rs" uniqKey="Lin R">RS Lin</name>
</author>
<author><name sortKey="Huang, Ch" uniqKey="Huang C">CH Huang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ng, Mh" uniqKey="Ng M">MH Ng</name>
</author>
<author><name sortKey="Lau, Km" uniqKey="Lau K">KM Lau</name>
</author>
<author><name sortKey="Li, L" uniqKey="Li L">L Li</name>
</author>
<author><name sortKey="Cheng, Sh" uniqKey="Cheng S">SH Cheng</name>
</author>
<author><name sortKey="Chan, Wy" uniqKey="Chan W">WY Chan</name>
</author>
<author><name sortKey="Hui, Pk" uniqKey="Hui P">PK Hui</name>
</author>
<author><name sortKey="Zee, B" uniqKey="Zee B">B Zee</name>
</author>
<author><name sortKey="Leung, Cb" uniqKey="Leung C">CB Leung</name>
</author>
<author><name sortKey="Sung, Jj" uniqKey="Sung J">JJ Sung</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, Vs" uniqKey="Chan V">VS Chan</name>
</author>
<author><name sortKey="Chan, Ky" uniqKey="Chan K">KY Chan</name>
</author>
<author><name sortKey="Chen, Y" uniqKey="Chen Y">Y Chen</name>
</author>
<author><name sortKey="Poon, Ll" uniqKey="Poon L">LL Poon</name>
</author>
<author><name sortKey="Cheung, An" uniqKey="Cheung A">AN Cheung</name>
</author>
<author><name sortKey="Zheng, B" uniqKey="Zheng B">B Zheng</name>
</author>
<author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name>
</author>
<author><name sortKey="Mak, W" uniqKey="Mak W">W Mak</name>
</author>
<author><name sortKey="Ngan, Hy" uniqKey="Ngan H">HY Ngan</name>
</author>
<author><name sortKey="Xu, X" uniqKey="Xu X">X Xu</name>
</author>
<author><name sortKey="Screaton, G" uniqKey="Screaton G">G Screaton</name>
</author>
<author><name sortKey="Tam, Pk" uniqKey="Tam P">PK Tam</name>
</author>
<author><name sortKey="Austyn, Jm" uniqKey="Austyn J">JM Austyn</name>
</author>
<author><name sortKey="Chan, Lc" uniqKey="Chan L">LC Chan</name>
</author>
<author><name sortKey="Yip, Sp" uniqKey="Yip S">SP Yip</name>
</author>
<author><name sortKey="Peiris, M" uniqKey="Peiris M">M Peiris</name>
</author>
<author><name sortKey="Khoo, Us" uniqKey="Khoo U">US Khoo</name>
</author>
<author><name sortKey="Lin, Cl" uniqKey="Lin C">CL Lin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gu, J" uniqKey="Gu J">J Gu</name>
</author>
<author><name sortKey="Taylor, Rc" uniqKey="Taylor R">RC Taylor</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Am J Pathol</journal-id>
<journal-id journal-id-type="iso-abbrev">Am. J. Pathol</journal-id>
<journal-title-group><journal-title>The American Journal of Pathology</journal-title>
</journal-title-group>
<issn pub-type="ppub">0002-9440</issn>
<issn pub-type="epub">1525-2191</issn>
<publisher><publisher-name>American Society for Investigative Pathology. Published by Elsevier Inc.</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">17392154</article-id>
<article-id pub-id-type="pmc">1829448</article-id>
<article-id pub-id-type="publisher-id">S0002-9440(10)61329-6</article-id>
<article-id pub-id-type="doi">10.2353/ajpath.2007.061088</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Pathology and Pathogenesis of Severe Acute Respiratory Syndrome</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Gu</surname>
<given-names>Jiang</given-names>
</name>
<email>jianggu@bmcu.edu.cn</email>
<xref rid="cor1" ref-type="corresp">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Korteweg</surname>
<given-names>Christine</given-names>
</name>
</contrib>
</contrib-group>
<aff>Department of Pathology and Infectious Disease Center, School of Basic Medical Sciences, Peking (Beijing) University, Beijing, China</aff>
<author-notes><corresp id="cor1"><label>*</label>
Address reprint requests to Jiang Gu, M.D., Ph.D., Professor and Chairman, Department of Pathology, Dean, School of Medical Sciences, Director, Infectious Disease Center, Peking (Beijing) University, 38 Xueyuan Rd., 100083 Beijing, China <email>jianggu@bmcu.edu.cn</email>
</corresp>
</author-notes>
<pub-date pub-type="pmc-release"><day>16</day>
<month>12</month>
<year>2010</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>4</month>
<year>2007</year>
</pub-date>
<pub-date pub-type="epub"><day>16</day>
<month>12</month>
<year>2010</year>
</pub-date>
<volume>170</volume>
<issue>4</issue>
<fpage>1136</fpage>
<lpage>1147</lpage>
<history><date date-type="accepted"><day>9</day>
<month>1</month>
<year>2007</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2007 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.</copyright-statement>
<copyright-year>2007</copyright-year>
<copyright-holder>American Society for Investigative Pathology</copyright-holder>
<license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
</license>
</permissions>
<abstract><p>Severe acute respiratory syndrome (SARS) is an emerging infectious viral disease characterized by severe clinical manifestations of the lower respiratory tract. The pathogenesis of SARS is highly complex, with multiple factors leading to severe injury in the lungs and dissemination of the virus to several other organs. The SARS coronavirus targets the epithelial cells of the respiratory tract, resulting in diffuse alveolar damage. Several organs/cell types may be infected in the course of the illness, including mucosal cells of the intestines, tubular epithelial cells of the kidneys, neurons of the brain, and several types of immune cells, and certain organs may suffer from indirect injury. Extensive studies have provided a basic understanding of the pathogenesis of this disease. In this review we describe the most significant pathological features of SARS, explore the etiological factors causing these pathological changes, and discuss the major pathogenetic mechanisms. The latter include dysregulation of cytokines/chemokines, deficiencies in the innate immune response, direct infection of immune cells, direct viral cytopathic effects, down-regulation of lung protective angiotensin converting enzyme 2, autoimmunity, and genetic factors. It seems that both abnormal immune responses and injury to immune cells may be key factors in the pathogenesis of this new disease.</p>
</abstract>
</article-meta>
</front>
</pmc>
<affiliations><list></list>
<tree><noCountry><name sortKey="Gu, Jiang" sort="Gu, Jiang" uniqKey="Gu J" first="Jiang" last="Gu">Jiang Gu</name>
<name sortKey="Korteweg, Christine" sort="Korteweg, Christine" uniqKey="Korteweg C" first="Christine" last="Korteweg">Christine Korteweg</name>
</noCountry>
</tree>
</affiliations>
</record>
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