SrasV1, PascalFrancis, Corpus, bibRecord, 000203

Determining SARS sub-clinical infection: A longitudinal seroepidemiological study in recovered SARS patients and controls after an outbreak in a general hospital

Identifieur interne : 000203 ( PascalFrancis/Corpus ); précédent : 000202; suivant : 000204

Determining SARS sub-clinical infection: A longitudinal seroepidemiological study in recovered SARS patients and controls after an outbreak in a general hospital

Auteurs : ZHEN YANG ; SHIXIN WANG ; QIAN LI ; YUMING LI ; MAOTI WEI ; HONGSHENG GAO ; Catherine Donovan ; Peizhong Peter Wang

Source :

Scandinavian journal of infectious diseases [ 0036-5548 ] ; 2009.

RBID : Pascal:09-0309841

Descripteurs français

Pascal (Inist)
- Syndrome respiratoire aigu sévère, Asymptomatique, Epidémiologie, Contrôle, Homme, Epidémie, Hôpital, Microbiologie.

English descriptors

KwdEn :
- Asymptomatic, Check, Epidemic, Epidemiology, Hospital, Human, Microbiology, Severe acute respiratory syndrome.

Abstract

A cohort of 67 confirmed SARS patients were prospectively followed for 16 months and were compared with a control population. Serum samples taken at various times were tested for IgG and IgM; dynamic serological changes in these antibodies were described. The positive responses of IgM and IgG antibodies in sera against SARS virus from the first week to the sixth week after onset of the illness in patients with SARS were measured. The ELISA test of IgG antibody was negative in 200 community controls. The positive rate in the SARS high-risk population was 0.61 % tested by ELISA and 0.21 % by IFA. The high-risk population in this study was defined as those who provided health care and other services to SARS patients during the outbreak. IgG antibody in convalescent serum of patients with SARS revealed an increasing trend, peaking at the 22nd week after onset of illness followed by a slow decline. IgM appeared earlier than IgG and can be better used for early detection. IgG remained at a high level for a much longer period, serving as a good indicator for follow-up and for assessing past exposure. Our results also suggest that sub-clinical infection, if it exists, is very rare.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A02	`01`			`@0 SJIDB7`
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A11	`02`	`1`		`@1 SHIXIN WANG`
A11	`03`	`1`		`@1 QIAN LI`
A11	`04`	`1`		`@1 YUMING LI`
A11	`05`	`1`		`@1 MAOTI WEI`
A11	`06`	`1`		`@1 HONGSHENG GAO`
A11	`07`	`1`		`@1 DONOVAN (Catherine)`
A11	`08`	`1`		`@1 WANG (Peizhong Peter)`
A14	`01`			`@1 Department of Science Research, Medical College of Chinese People's Armed Police Force @2 Tianjin @3 CHN @Z 1 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut.`
A14	`02`			`@1 Dongli Hospital @2 Tianjin @3 CHN @Z 2 aut.`
A14	`03`			`@1 Division of Community Health and Humanities, Faculty of Medicine, Memorial University of Newfoundland @3 CAN @Z 7 aut. @Z 8 aut.`
A14	`04`			`@1 School of Public Health, Tianjin Medical University @3 CHN @Z 8 aut.`
A20				`@1 507-510`
A21				`@1 2009`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 14662 @5 354000187174060170`
A44				`@0 0000 @1 © 2009 INIST-CNRS. All rights reserved.`
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C01	`01`		`ENG`	@0 A cohort of 67 confirmed SARS patients were prospectively followed for 16 months and were compared with a control population. Serum samples taken at various times were tested for IgG and IgM; dynamic serological changes in these antibodies were described. The positive responses of IgM and IgG antibodies in sera against SARS virus from the first week to the sixth week after onset of the illness in patients with SARS were measured. The ELISA test of IgG antibody was negative in 200 community controls. The positive rate in the SARS high-risk population was 0.61 % tested by ELISA and 0.21 % by IFA. The high-risk population in this study was defined as those who provided health care and other services to SARS patients during the outbreak. IgG antibody in convalescent serum of patients with SARS revealed an increasing trend, peaking at the 22nd week after onset of illness followed by a slow decline. IgM appeared earlier than IgG and can be better used for early detection. IgG remained at a high level for a much longer period, serving as a good indicator for follow-up and for assessing past exposure. Our results also suggest that sub-clinical infection, if it exists, is very rare.
C02	`01`	`X`		`@0 002B05C02C`
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C03	`01`	`X`	`ENG`	`@0 Severe acute respiratory syndrome @2 NM @5 01`
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C03	`02`	`X`	`SPA`	`@0 Asintomático @5 07`
C03	`03`	`X`	`FRE`	`@0 Epidémiologie @5 08`
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C03	`04`	`X`	`SPA`	`@0 Control @5 09`
C03	`05`	`X`	`FRE`	`@0 Homme @5 10`
C03	`05`	`X`	`ENG`	`@0 Human @5 10`
C03	`05`	`X`	`SPA`	`@0 Hombre @5 10`
C03	`06`	`X`	`FRE`	`@0 Epidémie @5 13`
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C03	`06`	`X`	`SPA`	`@0 Epidemia @5 13`
C03	`07`	`X`	`FRE`	`@0 Hôpital @5 14`
C03	`07`	`X`	`ENG`	`@0 Hospital @5 14`
C03	`07`	`X`	`SPA`	`@0 Hospital @5 14`
C03	`08`	`X`	`FRE`	`@0 Microbiologie @5 16`
C03	`08`	`X`	`ENG`	`@0 Microbiology @5 16`
C03	`08`	`X`	`SPA`	`@0 Microbiología @5 16`
C07	`01`	`X`	`FRE`	`@0 Virose`
C07	`01`	`X`	`ENG`	`@0 Viral disease`
C07	`01`	`X`	`SPA`	`@0 Virosis`
C07	`02`	`X`	`FRE`	`@0 Infection`
C07	`02`	`X`	`ENG`	`@0 Infection`
C07	`02`	`X`	`SPA`	`@0 Infección`
C07	`03`	`X`	`FRE`	`@0 Pathologie de l'appareil respiratoire @5 38`
C07	`03`	`X`	`ENG`	`@0 Respiratory disease @5 38`
C07	`03`	`X`	`SPA`	`@0 Aparato respiratorio patología @5 38`
C07	`04`	`X`	`FRE`	`@0 Pathologie des poumons @5 39`
C07	`04`	`X`	`ENG`	`@0 Lung disease @5 39`
C07	`04`	`X`	`SPA`	`@0 Pulmón patología @5 39`
C07	`05`	`X`	`FRE`	`@0 Prévention @5 40`
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N21				`@1 222`
N44	`01`			`@1 OTO`
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Format Inist (serveur)

NO :	PASCAL 09-0309841 INIST
ET :	Determining SARS sub-clinical infection: A longitudinal seroepidemiological study in recovered SARS patients and controls after an outbreak in a general hospital
AU :	ZHEN YANG; SHIXIN WANG; QIAN LI; YUMING LI; MAOTI WEI; HONGSHENG GAO; DONOVAN (Catherine); WANG (Peizhong Peter)
AF :	Department of Science Research, Medical College of Chinese People's Armed Police Force/Tianjin/Chine (1 aut., 3 aut., 4 aut., 5 aut., 6 aut.); Dongli Hospital/Tianjin/Chine (2 aut.); Division of Community Health and Humanities, Faculty of Medicine, Memorial University of Newfoundland/Canada (7 aut., 8 aut.); School of Public Health, Tianjin Medical University/Chine (8 aut.)
DT :	Publication en série; Niveau analytique
SO :	Scandinavian journal of infectious diseases; ISSN 0036-5548; Coden SJIDB7; Royaume-Uni; Da. 2009; Vol. 41; No. 6-7; Pp. 507-510; Bibl. 15 ref.
LA :	Anglais
EA :	A cohort of 67 confirmed SARS patients were prospectively followed for 16 months and were compared with a control population. Serum samples taken at various times were tested for IgG and IgM; dynamic serological changes in these antibodies were described. The positive responses of IgM and IgG antibodies in sera against SARS virus from the first week to the sixth week after onset of the illness in patients with SARS were measured. The ELISA test of IgG antibody was negative in 200 community controls. The positive rate in the SARS high-risk population was 0.61 % tested by ELISA and 0.21 % by IFA. The high-risk population in this study was defined as those who provided health care and other services to SARS patients during the outbreak. IgG antibody in convalescent serum of patients with SARS revealed an increasing trend, peaking at the 22nd week after onset of illness followed by a slow decline. IgM appeared earlier than IgG and can be better used for early detection. IgG remained at a high level for a much longer period, serving as a good indicator for follow-up and for assessing past exposure. Our results also suggest that sub-clinical infection, if it exists, is very rare.
CC :	002B05C02C
FD :	Syndrome respiratoire aigu sévère; Asymptomatique; Epidémiologie; Contrôle; Homme; Epidémie; Hôpital; Microbiologie
FG :	Virose; Infection; Pathologie de l'appareil respiratoire; Pathologie des poumons; Prévention
ED :	Severe acute respiratory syndrome; Asymptomatic; Epidemiology; Check; Human; Epidemic; Hospital; Microbiology
EG :	Viral disease; Infection; Respiratory disease; Lung disease; Prevention
SD :	Síndrome respiratorio agudo severo; Asintomático; Epidemiología; Control; Hombre; Epidemia; Hospital; Microbiología
LO :	INIST-14662.354000187174060170
ID :	09-0309841

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Pascal:09-0309841

Le document en format XML

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<front><div type="abstract" xml:lang="en">A cohort of 67 confirmed SARS patients were prospectively followed for 16 months and were compared with a control population. Serum samples taken at various times were tested for IgG and IgM; dynamic serological changes in these antibodies were described. The positive responses of IgM and IgG antibodies in sera against SARS virus from the first week to the sixth week after onset of the illness in patients with SARS were measured. The ELISA test of IgG antibody was negative in 200 community controls. The positive rate in the SARS high-risk population was 0.61 % tested by ELISA and 0.21 % by IFA. The high-risk population in this study was defined as those who provided health care and other services to SARS patients during the outbreak. IgG antibody in convalescent serum of patients with SARS revealed an increasing trend, peaking at the 22nd week after onset of illness followed by a slow decline. IgM appeared earlier than IgG and can be better used for early detection. IgG remained at a high level for a much longer period, serving as a good indicator for follow-up and for assessing past exposure. Our results also suggest that sub-clinical infection, if it exists, is very rare.</div>
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<server><NO>PASCAL 09-0309841 INIST</NO>
<ET>Determining SARS sub-clinical infection: A longitudinal seroepidemiological study in recovered SARS patients and controls after an outbreak in a general hospital</ET>
<AU>ZHEN YANG; SHIXIN WANG; QIAN LI; YUMING LI; MAOTI WEI; HONGSHENG GAO; DONOVAN (Catherine); WANG (Peizhong Peter)</AU>
<AF>Department of Science Research, Medical College of Chinese People's Armed Police Force/Tianjin/Chine (1 aut., 3 aut., 4 aut., 5 aut., 6 aut.); Dongli Hospital/Tianjin/Chine (2 aut.); Division of Community Health and Humanities, Faculty of Medicine, Memorial University of Newfoundland/Canada (7 aut., 8 aut.); School of Public Health, Tianjin Medical University/Chine (8 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Scandinavian journal of infectious diseases; ISSN 0036-5548; Coden SJIDB7; Royaume-Uni; Da. 2009; Vol. 41; No. 6-7; Pp. 507-510; Bibl. 15 ref.</SO>
<LA>Anglais</LA>
<EA>A cohort of 67 confirmed SARS patients were prospectively followed for 16 months and were compared with a control population. Serum samples taken at various times were tested for IgG and IgM; dynamic serological changes in these antibodies were described. The positive responses of IgM and IgG antibodies in sera against SARS virus from the first week to the sixth week after onset of the illness in patients with SARS were measured. The ELISA test of IgG antibody was negative in 200 community controls. The positive rate in the SARS high-risk population was 0.61 % tested by ELISA and 0.21 % by IFA. The high-risk population in this study was defined as those who provided health care and other services to SARS patients during the outbreak. IgG antibody in convalescent serum of patients with SARS revealed an increasing trend, peaking at the 22nd week after onset of illness followed by a slow decline. IgM appeared earlier than IgG and can be better used for early detection. IgG remained at a high level for a much longer period, serving as a good indicator for follow-up and for assessing past exposure. Our results also suggest that sub-clinical infection, if it exists, is very rare.</EA>
<CC>002B05C02C</CC>
<FD>Syndrome respiratoire aigu sévère; Asymptomatique; Epidémiologie; Contrôle; Homme; Epidémie; Hôpital; Microbiologie</FD>
<FG>Virose; Infection; Pathologie de l'appareil respiratoire; Pathologie des poumons; Prévention</FG>
<ED>Severe acute respiratory syndrome; Asymptomatic; Epidemiology; Check; Human; Epidemic; Hospital; Microbiology</ED>
<EG>Viral disease; Infection; Respiratory disease; Lung disease; Prevention</EG>
<SD>Síndrome respiratorio agudo severo; Asintomático; Epidemiología; Control; Hombre; Epidemia; Hospital; Microbiología</SD>
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Determining SARS sub-clinical infection: A longitudinal seroepidemiological study in recovered SARS patients and controls after an outbreak in a general hospital

Determining SARS sub-clinical infection: A longitudinal seroepidemiological study in recovered SARS patients and controls after an outbreak in a general hospital

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