SrasV1, PascalFrancis, Checkpoint, bibRecord, 000829

Inactivation of the coronavirus that induces severe acute respiratory syndrome, SARS-CoV

Identifieur interne : 000829 ( PascalFrancis/Checkpoint ); précédent : 000828; suivant : 000830

Inactivation of the coronavirus that induces severe acute respiratory syndrome, SARS-CoV

Auteurs : Miriam E. R. Darnell [États-Unis] ; Kanta Subbarao [États-Unis] ; Stephen M. Feinstone [États-Unis] ; Deborah R. Taylor [États-Unis]

Source :

Journal of virological methods [ 0166-0934 ] ; 2004.

RBID : Pascal:04-0535983

Descripteurs français

Pascal (Inist)
- Coronavirus, Culture tissu, Microbiologie, Méthode, Virologie, Syndrome respiratoire aigu sévère.

English descriptors

KwdEn :
- Coronavirus, Method, Microbiology, Severe acute respiratory syndrome, Tissue culture, Virology.

Abstract

Severe acute respiratory syndrome (SARS) is a life-threatening disease caused by a novel coronavirus termed SARS-CoV. Due to the severity of this disease, the World Health Organization (WHO) recommends that manipulation of active viral cultures of SARS-CoV be performed in containment laboratories at biosafety level 3 (BSL3). The virus was inactivated by ultraviolet light (UV) at 254 nm, heat treatment of 65 °C or greater, alkaline (pH > 12) or acidic (pH < 3) conditions, formalin and glutaraldehyde treatments. We describe the kinetics of these efficient viral inactivation methods, which will allow research with SARS-CoV containing materials, that are rendered non-infectious, to be conducted at reduced safety levels.

Affiliations:

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Pascal:04-0535983

Le document en format XML

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Inactivation of the coronavirus that induces severe acute respiratory syndrome, SARS-CoV

Inactivation of the coronavirus that induces severe acute respiratory syndrome, SARS-CoV

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri