Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020
Identifieur interne : 003349 ( Ncbi/Merge ); précédent : 003348; suivant : 003350Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020
Auteurs : Rui Liu [République populaire de Chine] ; Huan Han [République populaire de Chine] ; Fang Liu [République populaire de Chine] ; Zhihua Lv [République populaire de Chine] ; Kailang Wu [République populaire de Chine] ; Yingle Liu [République populaire de Chine] ; Yong Feng [République populaire de Chine] ; Chengliang Zhu [République populaire de Chine]Source :
- Clinica Chimica Acta; International Journal of Clinical Chemistry [ 0009-8981 ] ; 2020.
Descripteurs français
- KwdFr :
- ADN viral (analyse), Adolescent, Adulte, Adulte d'âge moyen, Appareil respiratoire (virologie), Chine (épidémiologie), Expectoration (virologie), Facteurs de l'âge, Facteurs de risque, Facteurs sexuels, Femelle, Flambées de maladies, Humains, Infections à coronavirus (diagnostic), Infections à coronavirus (épidémiologie), Jeune adulte, Liquide de lavage bronchoalvéolaire (virologie), Mâle, Nucléocapside (), Nucléocapside (génétique), Pandémies, Pneumopathie virale (diagnostic), Pneumopathie virale (épidémiologie), Réaction de polymérisation en chaine en temps réel (), Sujet âgé, Techniques de laboratoire clinique.
- MESH :
- analyse : ADN viral.
- diagnostic : Infections à coronavirus, Pneumopathie virale.
- génétique : Nucléocapside.
- virologie : Appareil respiratoire, Expectoration, Liquide de lavage bronchoalvéolaire.
- épidémiologie : Chine, Infections à coronavirus, Pneumopathie virale.
- Adolescent, Adulte, Adulte d'âge moyen, Facteurs de l'âge, Facteurs de risque, Facteurs sexuels, Femelle, Flambées de maladies, Humains, Jeune adulte, Mâle, Nucléocapside, Pandémies, Réaction de polymérisation en chaine en temps réel, Sujet âgé, Techniques de laboratoire clinique.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- Adolescent, Adult, Age Factors, Aged, Betacoronavirus (chemistry), Bronchoalveolar Lavage Fluid (virology), China (epidemiology), Clinical Laboratory Techniques, Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), DNA, Viral (analysis), Disease Outbreaks, Female, Humans, Male, Middle Aged, Nucleocapsid (chemistry), Nucleocapsid (genetics), Pandemics, Pneumonia, Viral (diagnosis), Pneumonia, Viral (epidemiology), Real-Time Polymerase Chain Reaction (methods), Respiratory System (virology), Risk Factors, Sex Factors, Sputum (virology), Young Adult.
- MESH :
- chemical , analysis : DNA, Viral.
- geographic , epidemiology : China.
- chemistry : Betacoronavirus, Nucleocapsid.
- diagnosis : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- genetics : Nucleocapsid.
- methods : Real-Time Polymerase Chain Reaction.
- virology : Bronchoalveolar Lavage Fluid, Respiratory System, Sputum.
- Adolescent, Adult, Age Factors, Aged, Clinical Laboratory Techniques, Disease Outbreaks, Female, Humans, Male, Middle Aged, Pandemics, Risk Factors, Sex Factors, Young Adult.
Abstract
The SARS-CoV-2 NAT positive rate was about 38% for the total 4880 specimens. Male and older population had a significant higher positive rates. 57% was positive among the specimens from the Fever Clinics. Age, not gender, was the risk factor for SARS-CoV-2 infection in fever clinics. Viral NAT played an important role in identifying SARS-CoV-2 infection.
Url:
DOI: 10.1016/j.cca.2020.03.009
PubMed: 32156607
PubMed Central: 7094385
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PMC:7094385Le document en format XML
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adulte</term><term>Mâle</term><term>Nucléocapside</term><term>Pandémies</term><term>Réaction de polymérisation en chaine en temps réel</term><term>Sujet âgé</term><term>Techniques de laboratoire clinique</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>République populaire de Chine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="l0005"><list-item id="o0005"><label>•</label><p id="p0005">The SARS-CoV-2 NAT positive rate was about 38% for the total 4880 specimens. Male and older population had a significant higher positive rates.</p></list-item><list-item id="o0010"><label>•</label><p id="p0010">57% was positive among the specimens from the Fever Clinics. Age, not gender, was the risk factor for SARS-CoV-2 infection in fever clinics.</p></list-item><list-item id="o0015"><label>•</label><p id="p0015">Viral NAT played an important role in identifying SARS-CoV-2 infection.</p></list-item></list></p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Fang, Y" uniqKey="Fang Y">Y. Fang</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H. Zhang</name></author><author><name sortKey="Xie, J" uniqKey="Xie J">J. Xie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xie, X" uniqKey="Xie X">X. Xie</name></author><author><name sortKey="Zhong, Z" uniqKey="Zhong Z">Z. Zhong</name></author><author><name sortKey="Zhao, W" uniqKey="Zhao W">W. Zhao</name></author><author><name sortKey="Zheng, C" uniqKey="Zheng C">C. Zheng</name></author><author><name sortKey="Wang, F" uniqKey="Wang F">F. Wang</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Q" uniqKey="Li Q">Q. Li</name></author><author><name sortKey="Guan, X" uniqKey="Guan X">X. Guan</name></author><author><name sortKey="Wu, P" uniqKey="Wu P">P. Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhu, N" uniqKey="Zhu N">N. Zhu</name></author><author><name sortKey="Zhang, D" uniqKey="Zhang D">D. Zhang</name></author><author><name sortKey="Wang, W" uniqKey="Wang W">W. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Hu, B" uniqKey="Hu B">B. Hu</name></author><author><name sortKey="Hu, C" uniqKey="Hu C">C. Hu</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chen, N" uniqKey="Chen N">N. Chen</name></author><author><name sortKey="Zhou, M" uniqKey="Zhou M">M. Zhou</name></author><author><name sortKey="Dong, X" uniqKey="Dong X">X. Dong</name></author></analytic></biblStruct></listBibl></div1></back></TEI><double pmid="32156607"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020</title><author><name sortKey="Liu, Rui" sort="Liu, Rui" uniqKey="Liu R" first="Rui" last="Liu">Rui Liu</name><affiliation wicri:level="1"><nlm:aff id="af005">Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Han, Huan" sort="Han, Huan" uniqKey="Han H" first="Huan" last="Han">Huan Han</name><affiliation wicri:level="1"><nlm:aff id="af005">Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Fang" sort="Liu, Fang" uniqKey="Liu F" first="Fang" last="Liu">Fang Liu</name><affiliation wicri:level="1"><nlm:aff id="af010">Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="af015">Dept.Wuhan Institute of Biotechnology, Wuhan 430075, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept.Wuhan Institute of Biotechnology, Wuhan 430075, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Lv, Zhihua" sort="Lv, Zhihua" uniqKey="Lv Z" first="Zhihua" last="Lv">Zhihua Lv</name><affiliation wicri:level="1"><nlm:aff id="af005">Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Kailang" sort="Wu, Kailang" uniqKey="Wu K" first="Kailang" last="Wu">Kailang Wu</name><affiliation wicri:level="1"><nlm:aff id="af010">Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Yingle" sort="Liu, Yingle" uniqKey="Liu Y" first="Yingle" last="Liu">Yingle Liu</name><affiliation wicri:level="1"><nlm:aff id="af010">Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Feng, Yong" sort="Feng, Yong" uniqKey="Feng Y" first="Yong" last="Feng">Yong Feng</name><affiliation wicri:level="4"><nlm:aff id="af020">School of Basic Medical Sciences, Wuhan University, Wuhan 430071, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>School of Basic Medical Sciences, Wuhan University, Wuhan 430071, Hubei</wicri:regionArea><orgName type="university">Université de Wuhan</orgName><placeName><settlement type="city">Wuhan</settlement><region type="province">Hubei</region></placeName></affiliation></author><author><name sortKey="Zhu, Chengliang" sort="Zhu, Chengliang" uniqKey="Zhu C" first="Chengliang" last="Zhu">Chengliang Zhu</name><affiliation wicri:level="1"><nlm:aff id="af005">Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">32156607</idno><idno type="pmc">7094385</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094385</idno><idno type="RBID">PMC:7094385</idno><idno type="doi">10.1016/j.cca.2020.03.009</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">000E91</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000E91</idno><idno type="wicri:Area/Pmc/Curation">000E91</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000E91</idno><idno type="wicri:Area/Pmc/Checkpoint">000148</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000148</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020</title><author><name sortKey="Liu, Rui" sort="Liu, Rui" uniqKey="Liu R" first="Rui" last="Liu">Rui Liu</name><affiliation wicri:level="1"><nlm:aff id="af005">Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Han, Huan" sort="Han, Huan" uniqKey="Han H" first="Huan" last="Han">Huan Han</name><affiliation wicri:level="1"><nlm:aff id="af005">Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Fang" sort="Liu, Fang" uniqKey="Liu F" first="Fang" last="Liu">Fang Liu</name><affiliation wicri:level="1"><nlm:aff id="af010">Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="af015">Dept.Wuhan Institute of Biotechnology, Wuhan 430075, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept.Wuhan Institute of Biotechnology, Wuhan 430075, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Lv, Zhihua" sort="Lv, Zhihua" uniqKey="Lv Z" first="Zhihua" last="Lv">Zhihua Lv</name><affiliation wicri:level="1"><nlm:aff id="af005">Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Kailang" sort="Wu, Kailang" uniqKey="Wu K" first="Kailang" last="Wu">Kailang Wu</name><affiliation wicri:level="1"><nlm:aff id="af010">Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Yingle" sort="Liu, Yingle" uniqKey="Liu Y" first="Yingle" last="Liu">Yingle Liu</name><affiliation wicri:level="1"><nlm:aff id="af010">Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept.State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Feng, Yong" sort="Feng, Yong" uniqKey="Feng Y" first="Yong" last="Feng">Yong Feng</name><affiliation wicri:level="4"><nlm:aff id="af020">School of Basic Medical Sciences, Wuhan University, Wuhan 430071, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>School of Basic Medical Sciences, Wuhan University, Wuhan 430071, Hubei</wicri:regionArea><orgName type="university">Université de Wuhan</orgName><placeName><settlement type="city">Wuhan</settlement><region type="province">Hubei</region></placeName></affiliation></author><author><name sortKey="Zhu, Chengliang" sort="Zhu, Chengliang" uniqKey="Zhu C" first="Chengliang" last="Zhu">Chengliang Zhu</name><affiliation wicri:level="1"><nlm:aff id="af005">Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author></analytic><series><title level="j">Clinica Chimica Acta; International Journal of Clinical Chemistry</title><idno type="ISSN">0009-8981</idno><idno type="eISSN">1873-3492</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="l0005"><list-item id="o0005"><label>•</label><p id="p0005">The SARS-CoV-2 NAT positive rate was about 38% for the total 4880 specimens. Male and older population had a significant higher positive rates.</p></list-item><list-item id="o0010"><label>•</label><p id="p0010">57% was positive among the specimens from the Fever Clinics. Age, not gender, was the risk factor for SARS-CoV-2 infection in fever clinics.</p></list-item><list-item id="o0015"><label>•</label><p id="p0015">Viral NAT played an important role in identifying SARS-CoV-2 infection.</p></list-item></list></p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Fang, Y" uniqKey="Fang Y">Y. Fang</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H. Zhang</name></author><author><name sortKey="Xie, J" uniqKey="Xie J">J. Xie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xie, X" uniqKey="Xie X">X. Xie</name></author><author><name sortKey="Zhong, Z" uniqKey="Zhong Z">Z. Zhong</name></author><author><name sortKey="Zhao, W" uniqKey="Zhao W">W. Zhao</name></author><author><name sortKey="Zheng, C" uniqKey="Zheng C">C. Zheng</name></author><author><name sortKey="Wang, F" uniqKey="Wang F">F. Wang</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Q" uniqKey="Li Q">Q. Li</name></author><author><name sortKey="Guan, X" uniqKey="Guan X">X. Guan</name></author><author><name sortKey="Wu, P" uniqKey="Wu P">P. Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhu, N" uniqKey="Zhu N">N. Zhu</name></author><author><name sortKey="Zhang, D" uniqKey="Zhang D">D. Zhang</name></author><author><name sortKey="Wang, W" uniqKey="Wang W">W. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Hu, B" uniqKey="Hu B">B. Hu</name></author><author><name sortKey="Hu, C" uniqKey="Hu C">C. Hu</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chen, N" uniqKey="Chen N">N. Chen</name></author><author><name sortKey="Zhou, M" uniqKey="Zhou M">M. Zhou</name></author><author><name sortKey="Dong, X" uniqKey="Dong X">X. Dong</name></author></analytic></biblStruct></listBibl></div1></back></TEI></pmc><pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020.</title><author><name sortKey="Liu, Rui" sort="Liu, Rui" uniqKey="Liu R" first="Rui" last="Liu">Rui Liu</name><affiliation wicri:level="1"><nlm:affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Han, Huan" sort="Han, Huan" uniqKey="Han H" first="Huan" last="Han">Huan Han</name><affiliation wicri:level="1"><nlm:affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Fang" sort="Liu, Fang" uniqKey="Liu F" first="Fang" last="Liu">Fang Liu</name><affiliation wicri:level="1"><nlm:affiliation>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China; Dept. Wuhan Institute of Biotechnology, Wuhan 430075, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China; Dept. Wuhan Institute of Biotechnology, Wuhan 430075, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Lv, Zhihua" sort="Lv, Zhihua" uniqKey="Lv Z" first="Zhihua" last="Lv">Zhihua Lv</name><affiliation wicri:level="1"><nlm:affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Kailang" sort="Wu, Kailang" uniqKey="Wu K" first="Kailang" last="Wu">Kailang Wu</name><affiliation wicri:level="1"><nlm:affiliation>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Yingle" sort="Liu, Yingle" uniqKey="Liu Y" first="Yingle" last="Liu">Yingle Liu</name><affiliation wicri:level="1"><nlm:affiliation>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Feng, Yong" sort="Feng, Yong" uniqKey="Feng Y" first="Yong" last="Feng">Yong Feng</name><affiliation wicri:level="4"><nlm:affiliation>School of Basic Medical Sciences, Wuhan University, Wuhan 430071, Hubei, China. Electronic address: yongfeng@whu.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>School of Basic Medical Sciences, Wuhan University, Wuhan 430071, Hubei</wicri:regionArea><orgName type="university">Université de Wuhan</orgName><placeName><settlement type="city">Wuhan</settlement><region type="province">Hubei</region></placeName></affiliation></author><author><name sortKey="Zhu, Chengliang" sort="Zhu, Chengliang" uniqKey="Zhu C" first="Chengliang" last="Zhu">Chengliang Zhu</name><affiliation wicri:level="1"><nlm:affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China. Electronic address: xinchengzhu@163.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32156607</idno><idno type="pmid">32156607</idno><idno type="doi">10.1016/j.cca.2020.03.009</idno><idno type="wicri:Area/PubMed/Corpus">000652</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000652</idno><idno type="wicri:Area/PubMed/Curation">000652</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000652</idno><idno type="wicri:Area/PubMed/Checkpoint">000333</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000333</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020.</title><author><name sortKey="Liu, Rui" sort="Liu, Rui" uniqKey="Liu R" first="Rui" last="Liu">Rui Liu</name><affiliation wicri:level="1"><nlm:affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Han, Huan" sort="Han, Huan" uniqKey="Han H" first="Huan" last="Han">Huan Han</name><affiliation wicri:level="1"><nlm:affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Fang" sort="Liu, Fang" uniqKey="Liu F" first="Fang" last="Liu">Fang Liu</name><affiliation wicri:level="1"><nlm:affiliation>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China; Dept. Wuhan Institute of Biotechnology, Wuhan 430075, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China; Dept. Wuhan Institute of Biotechnology, Wuhan 430075, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Lv, Zhihua" sort="Lv, Zhihua" uniqKey="Lv Z" first="Zhihua" last="Lv">Zhihua Lv</name><affiliation wicri:level="1"><nlm:affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Kailang" sort="Wu, Kailang" uniqKey="Wu K" first="Kailang" last="Wu">Kailang Wu</name><affiliation wicri:level="1"><nlm:affiliation>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Yingle" sort="Liu, Yingle" uniqKey="Liu Y" first="Yingle" last="Liu">Yingle Liu</name><affiliation wicri:level="1"><nlm:affiliation>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Feng, Yong" sort="Feng, Yong" uniqKey="Feng Y" first="Yong" last="Feng">Yong Feng</name><affiliation wicri:level="4"><nlm:affiliation>School of Basic Medical Sciences, Wuhan University, Wuhan 430071, Hubei, China. Electronic address: yongfeng@whu.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>School of Basic Medical Sciences, Wuhan University, Wuhan 430071, Hubei</wicri:regionArea><orgName type="university">Université de Wuhan</orgName><placeName><settlement type="city">Wuhan</settlement><region type="province">Hubei</region></placeName></affiliation></author><author><name sortKey="Zhu, Chengliang" sort="Zhu, Chengliang" uniqKey="Zhu C" first="Chengliang" last="Zhu">Chengliang Zhu</name><affiliation wicri:level="1"><nlm:affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China. Electronic address: xinchengzhu@163.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author></analytic><series><title level="j">Clinica chimica acta; international journal of clinical chemistry</title><idno type="eISSN">1873-3492</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Age Factors</term><term>Aged</term><term>Betacoronavirus (chemistry)</term><term>Bronchoalveolar Lavage Fluid (virology)</term><term>China (epidemiology)</term><term>Clinical Laboratory Techniques</term><term>Coronavirus Infections (diagnosis)</term><term>Coronavirus Infections (epidemiology)</term><term>DNA, Viral (analysis)</term><term>Disease Outbreaks</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Nucleocapsid (chemistry)</term><term>Nucleocapsid (genetics)</term><term>Pandemics</term><term>Pneumonia, Viral (diagnosis)</term><term>Pneumonia, Viral (epidemiology)</term><term>Real-Time Polymerase Chain Reaction (methods)</term><term>Respiratory System (virology)</term><term>Risk Factors</term><term>Sex Factors</term><term>Sputum (virology)</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ADN viral (analyse)</term><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Appareil respiratoire (virologie)</term><term>Chine (épidémiologie)</term><term>Expectoration (virologie)</term><term>Facteurs de l'âge</term><term>Facteurs de risque</term><term>Facteurs sexuels</term><term>Femelle</term><term>Flambées de maladies</term><term>Humains</term><term>Infections à coronavirus (diagnostic)</term><term>Infections à coronavirus (épidémiologie)</term><term>Jeune adulte</term><term>Liquide de lavage bronchoalvéolaire (virologie)</term><term>Mâle</term><term>Nucléocapside ()</term><term>Nucléocapside (génétique)</term><term>Pandémies</term><term>Pneumopathie virale (diagnostic)</term><term>Pneumopathie virale (épidémiologie)</term><term>Réaction de polymérisation en chaine en temps réel ()</term><term>Sujet âgé</term><term>Techniques de laboratoire clinique</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>DNA, Viral</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>China</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>ADN viral</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Betacoronavirus</term><term>Nucleocapsid</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Nucleocapsid</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Nucléocapside</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Real-Time Polymerase Chain Reaction</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Appareil respiratoire</term><term>Expectoration</term><term>Liquide de lavage bronchoalvéolaire</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Bronchoalveolar Lavage Fluid</term><term>Respiratory System</term><term>Sputum</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Chine</term><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Age Factors</term><term>Aged</term><term>Clinical Laboratory Techniques</term><term>Disease Outbreaks</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pandemics</term><term>Risk Factors</term><term>Sex Factors</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Facteurs de l'âge</term><term>Facteurs de risque</term><term>Facteurs sexuels</term><term>Femelle</term><term>Flambées de maladies</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Nucléocapside</term><term>Pandémies</term><term>Réaction de polymérisation en chaine en temps réel</term><term>Sujet âgé</term><term>Techniques de laboratoire clinique</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>République populaire de Chine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">There's an outbreak of a novel coronavirus (SARS-CoV-2) infection since December 2019, first in China, and currently with more than 80 thousand confirmed infection globally in 29 countries till March 2, 2020. Identification, isolation and caring for patients early are essential to limit human-to-human transmission including reducing secondary infections among close contacts and health care workers, preventing transmission amplification events. The RT-PCR detection of viral nucleic acid test (NAT) was one of the most quickly established laboratory diagnosis method in a novel viral pandemic, just as in this COVID-19 outbreak.</div></front></TEI></pubmed></double></record>Pour manipuler ce document sous Unix (Dilib)
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