SrasV1, PubMed, Curation, bibRecord, 000652

Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020.

Identifieur interne : 000652 ( PubMed/Curation ); précédent : 000651; suivant : 000653

Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020.

Auteurs : Rui Liu [République populaire de Chine] ; Huan Han [République populaire de Chine] ; Fang Liu [République populaire de Chine] ; Zhihua Lv [République populaire de Chine] ; Kailang Wu [République populaire de Chine] ; Yingle Liu [République populaire de Chine] ; Yong Feng [République populaire de Chine] ; Chengliang Zhu [République populaire de Chine]

Source :

Clinica chimica acta; international journal of clinical chemistry [ 1873-3492 ] ; 2020.

RBID : pubmed:32156607

Descripteurs français

KwdFr :
- ADN viral (analyse), Adolescent, Adulte, Adulte d'âge moyen, Appareil respiratoire (virologie), Chine (épidémiologie), Expectoration (virologie), Facteurs de l'âge, Facteurs de risque, Facteurs sexuels, Femelle, Flambées de maladies, Humains, Infections à coronavirus (diagnostic), Infections à coronavirus (épidémiologie), Jeune adulte, Liquide de lavage bronchoalvéolaire (virologie), Mâle, Nucléocapside (), Nucléocapside (génétique), Pandémies, Pneumopathie virale (diagnostic), Pneumopathie virale (épidémiologie), Réaction de polymérisation en chaine en temps réel (), Sujet âgé, Techniques de laboratoire clinique.
MESH :
- analyse : ADN viral.
- diagnostic : Infections à coronavirus, Pneumopathie virale.
- génétique : Nucléocapside.
- virologie : Appareil respiratoire, Expectoration, Liquide de lavage bronchoalvéolaire.
- épidémiologie : Chine, Infections à coronavirus, Pneumopathie virale.
- Adolescent, Adulte, Adulte d'âge moyen, Facteurs de l'âge, Facteurs de risque, Facteurs sexuels, Femelle, Flambées de maladies, Humains, Jeune adulte, Mâle, Nucléocapside, Pandémies, Réaction de polymérisation en chaine en temps réel, Sujet âgé, Techniques de laboratoire clinique.
Wicri :
- geographic : République populaire de Chine.

English descriptors

KwdEn :
- Adolescent, Adult, Age Factors, Aged, Betacoronavirus (chemistry), Bronchoalveolar Lavage Fluid (virology), China (epidemiology), Clinical Laboratory Techniques, Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), DNA, Viral (analysis), Disease Outbreaks, Female, Humans, Male, Middle Aged, Nucleocapsid (chemistry), Nucleocapsid (genetics), Pandemics, Pneumonia, Viral (diagnosis), Pneumonia, Viral (epidemiology), Real-Time Polymerase Chain Reaction (methods), Respiratory System (virology), Risk Factors, Sex Factors, Sputum (virology), Young Adult.
MESH :
- chemical , analysis : DNA, Viral.
- geographic , epidemiology : China.
- chemistry : Betacoronavirus, Nucleocapsid.
- diagnosis : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- genetics : Nucleocapsid.
- methods : Real-Time Polymerase Chain Reaction.
- virology : Bronchoalveolar Lavage Fluid, Respiratory System, Sputum.
- Adolescent, Adult, Age Factors, Aged, Clinical Laboratory Techniques, Disease Outbreaks, Female, Humans, Male, Middle Aged, Pandemics, Risk Factors, Sex Factors, Young Adult.

Abstract

There's an outbreak of a novel coronavirus (SARS-CoV-2) infection since December 2019, first in China, and currently with more than 80 thousand confirmed infection globally in 29 countries till March 2, 2020. Identification, isolation and caring for patients early are essential to limit human-to-human transmission including reducing secondary infections among close contacts and health care workers, preventing transmission amplification events. The RT-PCR detection of viral nucleic acid test (NAT) was one of the most quickly established laboratory diagnosis method in a novel viral pandemic, just as in this COVID-19 outbreak.

DOI: 10.1016/j.cca.2020.03.009
PubMed: 32156607

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<front><div type="abstract" xml:lang="en">There's an outbreak of a novel coronavirus (SARS-CoV-2) infection since December 2019, first in China, and currently with more than 80 thousand confirmed infection globally in 29 countries till March 2, 2020. Identification, isolation and caring for patients early are essential to limit human-to-human transmission including reducing secondary infections among close contacts and health care workers, preventing transmission amplification events. The RT-PCR detection of viral nucleic acid test (NAT) was one of the most quickly established laboratory diagnosis method in a novel viral pandemic, just as in this COVID-19 outbreak.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32156607</PMID>
<DateCompleted><Year>2020</Year>
<Month>04</Month>
<Day>17</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>17</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-3492</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>505</Volume>
<PubDate><Year>2020</Year>
<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>Clinica chimica acta; international journal of clinical chemistry</Title>
<ISOAbbreviation>Clin. Chim. Acta</ISOAbbreviation>
</Journal>
<ArticleTitle>Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020.</ArticleTitle>
<Pagination><MedlinePgn>172-175</MedlinePgn>
</Pagination>
<ELocationID EIdType="pii" ValidYN="Y">S0009-8981(20)30112-1</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.cca.2020.03.009</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">There's an outbreak of a novel coronavirus (SARS-CoV-2) infection since December 2019, first in China, and currently with more than 80 thousand confirmed infection globally in 29 countries till March 2, 2020. Identification, isolation and caring for patients early are essential to limit human-to-human transmission including reducing secondary infections among close contacts and health care workers, preventing transmission amplification events. The RT-PCR detection of viral nucleic acid test (NAT) was one of the most quickly established laboratory diagnosis method in a novel viral pandemic, just as in this COVID-19 outbreak.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">4880 cases that had respiratory infection symptoms or close contact with COVID-19 patients in hospital in Wuhan, China, were tested for SARS-CoV-2 infection by use of quantitative RT-PCR (qRT-PCR) on samples from the respiratory tract. Positive rates were calculated in groups divided by genders or ages.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The positive rate was about 38% for the total 4880 specimens. Male and older population had a significant higher positive rates. However, 57% was positive among the specimens from the Fever Clinics. Binary logistic regression analysis showed that age, not gender, was the risk factor for SARS-CoV-2 infection in fever clinics.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Therefore, we concluded that viral NAT played an important role in identifying SARS-CoV-2 infection.</AbstractText>
<CopyrightInformation>Copyright © 2020 Elsevier B.V. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Rui</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Han</LastName>
<ForeName>Huan</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Fang</ForeName>
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<AffiliationInfo><Affiliation>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China; Dept. Wuhan Institute of Biotechnology, Wuhan 430075, Hubei, China.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Lv</LastName>
<ForeName>Zhihua</ForeName>
<Initials>Z</Initials>
<AffiliationInfo><Affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wu</LastName>
<ForeName>Kailang</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Yingle</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Dept. State Key Laboratory of Virology (Wuhan University), College of Life Sciences of Wuhan University, Wuhan 430072, Hubei, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Feng</LastName>
<ForeName>Yong</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>School of Basic Medical Sciences, Wuhan University, Wuhan 430071, Hubei, China. Electronic address: yongfeng@whu.edu.cn.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhu</LastName>
<ForeName>Chengliang</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Dept. of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China. Electronic address: xinchengzhu@163.com.</Affiliation>
</AffiliationInfo>
</Author>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>03</Month>
<Day>07</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Netherlands</Country>
<MedlineTA>Clin Chim Acta</MedlineTA>
<NlmUniqueID>1302422</NlmUniqueID>
<ISSNLinking>0009-8981</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D004279">DNA, Viral</NameOfSubstance>
</Chemical>
</ChemicalList>
<SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName>
<SupplMeshName Type="Protocol" UI="C000657964">COVID-19 diagnostic testing</SupplMeshName>
<SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName>
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<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000367" MajorTopicYN="N">Age Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001992" MajorTopicYN="N">Bronchoalveolar Lavage Fluid</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002681" MajorTopicYN="N" Type="Geographic">China</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
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<MeshHeading><DescriptorName UI="D019411" MajorTopicYN="N">Clinical Laboratory Techniques</DescriptorName>
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<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
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<MeshHeading><DescriptorName UI="D004279" MajorTopicYN="N">DNA, Viral</DescriptorName>
<QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName>
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<MeshHeading><DescriptorName UI="D004196" MajorTopicYN="N">Disease Outbreaks</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
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<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D019251" MajorTopicYN="N">Nucleocapsid</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
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<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
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<MeshHeading><DescriptorName UI="D060888" MajorTopicYN="N">Real-Time Polymerase Chain Reaction</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
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<MeshHeading><DescriptorName UI="D012137" MajorTopicYN="N">Respiratory System</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
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<MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012737" MajorTopicYN="N">Sex Factors</DescriptorName>
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<MeshHeading><DescriptorName UI="D013183" MajorTopicYN="N">Sputum</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
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</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword>
<Keyword MajorTopicYN="N">Nucleic acid test</Keyword>
<Keyword MajorTopicYN="N">Positive rate</Keyword>
<Keyword MajorTopicYN="N">SARS-CoV-2</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year>
<Month>03</Month>
<Day>02</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2020</Year>
<Month>03</Month>
<Day>06</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2020</Year>
<Month>3</Month>
<Day>12</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>4</Month>
<Day>18</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>3</Month>
<Day>12</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32156607</ArticleId>
<ArticleId IdType="pii">S0009-8981(20)30112-1</ArticleId>
<ArticleId IdType="doi">10.1016/j.cca.2020.03.009</ArticleId>
<ArticleId IdType="pmc">PMC7094385</ArticleId>
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   |texte=   Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020.
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Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020.

Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020.

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