SrasV1, Ncbi, Merge, bibRecord, 000A92

Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1.

Identifieur interne : 000A92 ( Ncbi/Merge ); précédent : 000A91; suivant : 000A93

Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1.

Auteurs : Robert J. Hogan [États-Unis] ; Guangping Gao ; Thomas Rowe ; Peter Bell ; Douglas Flieder ; Jason Paragas ; Gary P. Kobinger ; Nelson A. Wivel ; Ronald G. Crystal ; Julie Boyer ; Heinz Feldmann ; Thomas G. Voss ; James M. Wilson

Source :

Journal of virology [ 0022-538X ] ; 2004.

RBID : pubmed:15452265

Descripteurs français

KwdFr :
- Animaux, Bronchiolite virale (virologie), Facteur de transcription STAT-1, Immunohistochimie, Poumon (anatomopathologie), Poumon (virologie), Protéines de liaison à l'ADN (génétique), Protéines de liaison à l'ADN (métabolisme), Souris, Syndrome respiratoire aigu sévère (anatomopathologie), Syndrome respiratoire aigu sévère (immunologie), Syndrome respiratoire aigu sévère (physiopathologie), Syndrome respiratoire aigu sévère (virologie), Transactivateurs (génétique), Transactivateurs (métabolisme), Virus du SRAS (pathogénicité).
MESH :
- anatomopathologie : Poumon, Syndrome respiratoire aigu sévère.
- génétique : Protéines de liaison à l'ADN, Transactivateurs.
- immunologie : Syndrome respiratoire aigu sévère.
- métabolisme : Protéines de liaison à l'ADN, Transactivateurs.
- pathogénicité : Virus du SRAS.
- physiopathologie : Syndrome respiratoire aigu sévère.
- virologie : Bronchiolite virale, Poumon, Syndrome respiratoire aigu sévère.
- Animaux, Facteur de transcription STAT-1, Immunohistochimie, Souris.

English descriptors

KwdEn :
- Animals, Bronchiolitis, Viral (virology), DNA-Binding Proteins (genetics), DNA-Binding Proteins (metabolism), Immunohistochemistry, Lung (pathology), Lung (virology), Mice, SARS Virus (pathogenicity), STAT1 Transcription Factor, Severe Acute Respiratory Syndrome (immunology), Severe Acute Respiratory Syndrome (pathology), Severe Acute Respiratory Syndrome (physiopathology), Severe Acute Respiratory Syndrome (virology), Trans-Activators (genetics), Trans-Activators (metabolism).
MESH :
- chemical , genetics : DNA-Binding Proteins, Trans-Activators.
- chemical , metabolism : DNA-Binding Proteins, Trans-Activators.
- immunology : Severe Acute Respiratory Syndrome.
- pathogenicity : SARS Virus.
- pathology : Lung, Severe Acute Respiratory Syndrome.
- physiopathology : Severe Acute Respiratory Syndrome.
- virology : Bronchiolitis, Viral, Lung, Severe Acute Respiratory Syndrome.
- Animals, Immunohistochemistry, Mice, STAT1 Transcription Factor.

Abstract

Intranasal inhalation of the severe acute respiratory syndrome coronavirus (SARS CoV) in the immunocompetent mouse strain 129SvEv resulted in infection of conducting airway epithelial cells followed by rapid clearance of virus from the lungs and the development of self-limited bronchiolitis. Animals resistant to the effects of interferons by virtue of a deficiency in Stat1 demonstrated a markedly different course following intranasal inhalation of SARS CoV, one characterized by replication of virus in lungs and progressively worsening pulmonary disease with inflammation of small airways and alveoli and systemic spread of the virus to livers and spleens.

DOI: 10.1128/JVI.78.20.11416-11421.2004
PubMed: 15452265

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 002B36
to stream PubMed, to step Curation: 002B36
to stream PubMed, to step Checkpoint: 002B08

Links to Exploration step

pubmed:15452265

Le document en format XML

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<front><div type="abstract" xml:lang="en">Intranasal inhalation of the severe acute respiratory syndrome coronavirus (SARS CoV) in the immunocompetent mouse strain 129SvEv resulted in infection of conducting airway epithelial cells followed by rapid clearance of virus from the lungs and the development of self-limited bronchiolitis. Animals resistant to the effects of interferons by virtue of a deficiency in Stat1 demonstrated a markedly different course following intranasal inhalation of SARS CoV, one characterized by replication of virus in lungs and progressively worsening pulmonary disease with inflammation of small airways and alveoli and systemic spread of the virus to livers and spleens.</div>
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<Abstract><AbstractText>Intranasal inhalation of the severe acute respiratory syndrome coronavirus (SARS CoV) in the immunocompetent mouse strain 129SvEv resulted in infection of conducting airway epithelial cells followed by rapid clearance of virus from the lungs and the development of self-limited bronchiolitis. Animals resistant to the effects of interferons by virtue of a deficiency in Stat1 demonstrated a markedly different course following intranasal inhalation of SARS CoV, one characterized by replication of virus in lungs and progressively worsening pulmonary disease with inflammation of small airways and alveoli and systemic spread of the virus to livers and spleens.</AbstractText>
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</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Alabama</li>
</region>
</list>
<tree><noCountry><name sortKey="Bell, Peter" sort="Bell, Peter" uniqKey="Bell P" first="Peter" last="Bell">Peter Bell</name>
<name sortKey="Boyer, Julie" sort="Boyer, Julie" uniqKey="Boyer J" first="Julie" last="Boyer">Julie Boyer</name>
<name sortKey="Crystal, Ronald G" sort="Crystal, Ronald G" uniqKey="Crystal R" first="Ronald G" last="Crystal">Ronald G. Crystal</name>
<name sortKey="Feldmann, Heinz" sort="Feldmann, Heinz" uniqKey="Feldmann H" first="Heinz" last="Feldmann">Heinz Feldmann</name>
<name sortKey="Flieder, Douglas" sort="Flieder, Douglas" uniqKey="Flieder D" first="Douglas" last="Flieder">Douglas Flieder</name>
<name sortKey="Gao, Guangping" sort="Gao, Guangping" uniqKey="Gao G" first="Guangping" last="Gao">Guangping Gao</name>
<name sortKey="Kobinger, Gary P" sort="Kobinger, Gary P" uniqKey="Kobinger G" first="Gary P" last="Kobinger">Gary P. Kobinger</name>
<name sortKey="Paragas, Jason" sort="Paragas, Jason" uniqKey="Paragas J" first="Jason" last="Paragas">Jason Paragas</name>
<name sortKey="Rowe, Thomas" sort="Rowe, Thomas" uniqKey="Rowe T" first="Thomas" last="Rowe">Thomas Rowe</name>
<name sortKey="Voss, Thomas G" sort="Voss, Thomas G" uniqKey="Voss T" first="Thomas G" last="Voss">Thomas G. Voss</name>
<name sortKey="Wilson, James M" sort="Wilson, James M" uniqKey="Wilson J" first="James M" last="Wilson">James M. Wilson</name>
<name sortKey="Wivel, Nelson A" sort="Wivel, Nelson A" uniqKey="Wivel N" first="Nelson A" last="Wivel">Nelson A. Wivel</name>
</noCountry>
<country name="États-Unis"><region name="Alabama"><name sortKey="Hogan, Robert J" sort="Hogan, Robert J" uniqKey="Hogan R" first="Robert J" last="Hogan">Robert J. Hogan</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Ncbi/Merge

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A92 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 000A92 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    Ncbi
   |étape=   Merge
   |type=    RBID
   |clé=     pubmed:15452265
   |texte=   Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i   -Sk "pubmed:15452265" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd   \
       | NlmPubMed2Wicri -a SrasV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration SRAS

Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1.

Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki