Human respiratory coronaviruses : neuroinvasive, neurotropic and potentially neurovirulent pathogens.
Identifieur interne : 003794 ( Ncbi/Curation ); précédent : 003793; suivant : 003795Human respiratory coronaviruses : neuroinvasive, neurotropic and potentially neurovirulent pathogens.
Auteurs : Marc Desforges [Canada] ; Alain Le Coupanec [Canada] ; Élodie Brison [Canada] ; Mathieu Meessen-Pinard [Canada] ; Pierre J. Talbot [Canada]Source :
- Virologie (Montrouge, France) [ 1267-8694 ] ; 2014.
Abstract
In humans, viral infections of the respiratory tract are a leading cause of morbidity and mortality worldwide. Among the various respiratory viruses, coronaviruses are important ubiquitous pathogens of humans and animals. Since the late 1960's, human coronaviruses (HCoV) are recognized pathogens of the upper respiratory tract, being mainly associated with mild pathologies such as the common cold. However, in vulnerable populations, (newborns, infants, the elderly and immune-compromised individuals), they can affect the lower respiratory tract, leading to pneumonia, exacerbations of asthma, respiratory distress syndrome or even severe acute respiratory syndrome (SARS). For almost three decades now, the scientific literature has also demonstrated that HCoV are neuroinvasive and neurotropic: neurons are often the target cell in the central nervous system (CNS), inducing neurodegeneration and eventually death. Moreover, HCoV can contribute to an overactivation of the immune system that could lead to autoimmunity in the CNS of susceptible individuals. Given all these properties, it has been suggested that HCoV could be associated with the triggering or the exacerbation of human neurological diseases for which the etiology remains unknown or poorly understood.
DOI: 10.1684/vir.2014.0544
PubMed: 32260043
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001057
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :001057
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000F87
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :003794
Links to Exploration step
pubmed:32260043Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Human respiratory coronaviruses : neuroinvasive, neurotropic and potentially neurovirulent pathogens.</title>
<author><name sortKey="Desforges, Marc" sort="Desforges, Marc" uniqKey="Desforges M" first="Marc" last="Desforges">Marc Desforges</name>
<affiliation wicri:level="1"><nlm:affiliation>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec), Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec)</wicri:regionArea>
<wicri:noRegion>H7V 1B7 Laval (Québec)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Le Coupanec, Alain" sort="Le Coupanec, Alain" uniqKey="Le Coupanec A" first="Alain" last="Le Coupanec">Alain Le Coupanec</name>
<affiliation wicri:level="1"><nlm:affiliation>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec), Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec)</wicri:regionArea>
<wicri:noRegion>H7V 1B7 Laval (Québec)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Brison, Elodie" sort="Brison, Elodie" uniqKey="Brison E" first="Élodie" last="Brison">Élodie Brison</name>
<affiliation wicri:level="1"><nlm:affiliation>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec), Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec)</wicri:regionArea>
<wicri:noRegion>H7V 1B7 Laval (Québec)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Meessen Pinard, Mathieu" sort="Meessen Pinard, Mathieu" uniqKey="Meessen Pinard M" first="Mathieu" last="Meessen-Pinard">Mathieu Meessen-Pinard</name>
<affiliation wicri:level="1"><nlm:affiliation>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec), Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec)</wicri:regionArea>
<wicri:noRegion>H7V 1B7 Laval (Québec)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Talbot, Pierre J" sort="Talbot, Pierre J" uniqKey="Talbot P" first="Pierre J" last="Talbot">Pierre J. Talbot</name>
<affiliation wicri:level="1"><nlm:affiliation>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec), Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec)</wicri:regionArea>
<wicri:noRegion>H7V 1B7 Laval (Québec)</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2014">2014</date>
<idno type="RBID">pubmed:32260043</idno>
<idno type="pmid">32260043</idno>
<idno type="doi">10.1684/vir.2014.0544</idno>
<idno type="wicri:Area/PubMed/Corpus">001057</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001057</idno>
<idno type="wicri:Area/PubMed/Curation">001057</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001057</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000F87</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000F87</idno>
<idno type="wicri:Area/Ncbi/Merge">003794</idno>
<idno type="wicri:Area/Ncbi/Curation">003794</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Human respiratory coronaviruses : neuroinvasive, neurotropic and potentially neurovirulent pathogens.</title>
<author><name sortKey="Desforges, Marc" sort="Desforges, Marc" uniqKey="Desforges M" first="Marc" last="Desforges">Marc Desforges</name>
<affiliation wicri:level="1"><nlm:affiliation>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec), Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec)</wicri:regionArea>
<wicri:noRegion>H7V 1B7 Laval (Québec)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Le Coupanec, Alain" sort="Le Coupanec, Alain" uniqKey="Le Coupanec A" first="Alain" last="Le Coupanec">Alain Le Coupanec</name>
<affiliation wicri:level="1"><nlm:affiliation>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec), Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec)</wicri:regionArea>
<wicri:noRegion>H7V 1B7 Laval (Québec)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Brison, Elodie" sort="Brison, Elodie" uniqKey="Brison E" first="Élodie" last="Brison">Élodie Brison</name>
<affiliation wicri:level="1"><nlm:affiliation>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec), Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec)</wicri:regionArea>
<wicri:noRegion>H7V 1B7 Laval (Québec)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Meessen Pinard, Mathieu" sort="Meessen Pinard, Mathieu" uniqKey="Meessen Pinard M" first="Mathieu" last="Meessen-Pinard">Mathieu Meessen-Pinard</name>
<affiliation wicri:level="1"><nlm:affiliation>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec), Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec)</wicri:regionArea>
<wicri:noRegion>H7V 1B7 Laval (Québec)</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Talbot, Pierre J" sort="Talbot, Pierre J" uniqKey="Talbot P" first="Pierre J" last="Talbot">Pierre J. Talbot</name>
<affiliation wicri:level="1"><nlm:affiliation>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec), Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>INRS-Institut Armand-Frappier, laboratoire de neuroimmunovirologie, 531, boulevard des Prairies, H7V 1B7 Laval (Québec)</wicri:regionArea>
<wicri:noRegion>H7V 1B7 Laval (Québec)</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Virologie (Montrouge, France)</title>
<idno type="ISSN">1267-8694</idno>
<imprint><date when="2014" type="published">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">In humans, viral infections of the respiratory tract are a leading cause of morbidity and mortality worldwide. Among the various respiratory viruses, coronaviruses are important ubiquitous pathogens of humans and animals. Since the late 1960's, human coronaviruses (HCoV) are recognized pathogens of the upper respiratory tract, being mainly associated with mild pathologies such as the common cold. However, in vulnerable populations, (newborns, infants, the elderly and immune-compromised individuals), they can affect the lower respiratory tract, leading to pneumonia, exacerbations of asthma, respiratory distress syndrome or even severe acute respiratory syndrome (SARS). For almost three decades now, the scientific literature has also demonstrated that HCoV are neuroinvasive and neurotropic: neurons are often the target cell in the central nervous system (CNS), inducing neurodegeneration and eventually death. Moreover, HCoV can contribute to an overactivation of the immune system that could lead to autoimmunity in the CNS of susceptible individuals. Given all these properties, it has been suggested that HCoV could be associated with the triggering or the exacerbation of human neurological diseases for which the etiology remains unknown or poorly understood.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003794 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 003794 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= Ncbi |étape= Curation |type= RBID |clé= pubmed:32260043 |texte= Human respiratory coronaviruses : neuroinvasive, neurotropic and potentially neurovirulent pathogens. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:32260043" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a SrasV1
This area was generated with Dilib version V0.6.33. |