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Expression and functional characterisation of the putative SARS coronavirus non-structural proteins X1-X5.

Identifieur interne : 001D20 ( Ncbi/Curation ); précédent : 001D19; suivant : 001D21

Expression and functional characterisation of the putative SARS coronavirus non-structural proteins X1-X5.

Auteurs : Y Y Ho [Hong Kong]

Source :

RBID : pubmed:18708666

Descripteurs français

English descriptors

Abstract

1. We produced mammalian expression vectors encoding the SARS coronavirus (SARS-CoV) accessory proteins with or without the fluorescence protein tag and cell lines with stable expression of these proteins. 2. The cellular localisation and function of the SARS-CoV accessory proteins was determined. 3. SARS 6 and SARS 8b proteins are localised to the endoplasmic reticulum and nucleus/cytoplasm, respectively, and both proteins stimulate host cell DNA synthesis.

PubMed: 18708666

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Le document en format XML

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<term>Cell Survival (physiology)</term>
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<term>Chlorocebus aethiops</term>
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