Emerging Respiratory Viruses: Challenges and Vaccine Strategies
Identifieur interne : 001732 ( Ncbi/Curation ); précédent : 001731; suivant : 001733Emerging Respiratory Viruses: Challenges and Vaccine Strategies
Auteurs : Laura Gillim-Ross [États-Unis] ; Kanta Subbarao [États-Unis]Source :
- Clinical Microbiology Reviews [ 0893-8512 ] ; 2006.
Descripteurs français
- KwdFr :
- Animaux, Grippe humaine (génétique), Grippe humaine (transmission), Humains, Infections de l'appareil respiratoire (), Infections de l'appareil respiratoire (virologie), Infections de l'appareil respiratoire (épidémiologie), Infections à Paramyxoviridae (), Infections à Paramyxoviridae (virologie), Infections à Paramyxoviridae (épidémiologie), Maladies virales (), Maladies virales (transmission), Maladies virales (virologie), Maladies virales (épidémiologie), Metapneumovirus (isolement et purification), Vaccins antiviraux (administration et posologie), Vaccins antiviraux (immunologie), Virus de la grippe A (génétique), Virus de la grippe A (physiologie), Virus du SRAS (isolement et purification), Zoonoses (virologie).
- MESH :
- administration et posologie : Vaccins antiviraux.
- génétique : Grippe humaine, Virus de la grippe A.
- immunologie : Vaccins antiviraux.
- isolement et purification : Metapneumovirus, Virus du SRAS.
- physiologie : Virus de la grippe A.
- virologie : Infections de l'appareil respiratoire, Infections à Paramyxoviridae, Maladies virales, Zoonoses.
- épidémiologie : Grippe humaine, Infections de l'appareil respiratoire, Infections à Paramyxoviridae, Maladies virales.
- Animaux, Humains, Infections de l'appareil respiratoire, Infections à Paramyxoviridae, Maladies virales.
English descriptors
- KwdEn :
- Animals, Humans, Influenza A virus (genetics), Influenza A virus (physiology), Influenza, Human (genetics), Influenza, Human (transmission), Metapneumovirus (isolation & purification), Paramyxoviridae Infections (epidemiology), Paramyxoviridae Infections (prevention & control), Paramyxoviridae Infections (virology), Respiratory Tract Infections (epidemiology), Respiratory Tract Infections (prevention & control), Respiratory Tract Infections (virology), SARS Virus (isolation & purification), Viral Vaccines (administration & dosage), Viral Vaccines (immunology), Virus Diseases (epidemiology), Virus Diseases (prevention & control), Virus Diseases (transmission), Virus Diseases (virology), Zoonoses (virology).
- MESH :
- chemical , administration & dosage : Viral Vaccines.
- epidemiology : Paramyxoviridae Infections, Respiratory Tract Infections, Virus Diseases.
- genetics : Influenza A virus, Influenza, Human.
- chemical , immunology : Viral Vaccines.
- isolation & purification : Metapneumovirus, SARS Virus.
- physiology : Influenza A virus.
- prevention & control : Paramyxoviridae Infections, Respiratory Tract Infections, Virus Diseases.
- transmission : Influenza, Human, Virus Diseases.
- virology : Paramyxoviridae Infections, Respiratory Tract Infections, Virus Diseases, Zoonoses.
- Animals, Humans.
Abstract
The current threat of avian influenza to the human population, the potential for the reemergence of severe acute respiratory syndrome (SARS)-associated coronavirus, and the identification of multiple novel respiratory viruses underline the necessity for the development of therapeutic and preventive strategies to combat viral infection. Vaccine development is a key component in the prevention of widespread viral infection and in the reduction of morbidity and mortality associated with many viral infections. In this review we describe the different approaches currently being evaluated in the development of vaccines against SARS-associated coronavirus and avian influenza viruses and also highlight the many obstacles encountered in the development of these vaccines. Lessons learned from current vaccine studies, coupled with our increasing knowledge of the host and viral factors involved in viral pathogenesis, will help to increase the speed with which efficacious vaccines targeting newly emerging viral pathogens can be developed.
Url:
DOI: 10.1128/CMR.00005-06
PubMed: 17041137
PubMed Central: 1592697
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PMC:1592697Le document en format XML
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