Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.
Identifieur interne : 001126 ( Ncbi/Checkpoint ); précédent : 001125; suivant : 001127Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.
Auteurs : Martin J. Vincent [États-Unis] ; Eric Bergeron ; Suzanne Benjannet ; Bobbie R. Erickson ; Pierre E. Rollin ; Thomas G. Ksiazek ; Nabil G. Seidah ; Stuart T. NicholSource :
- Virology journal [ 1743-422X ] ; 2005.
Descripteurs français
- KwdFr :
- Animaux, Antiviraux (pharmacologie), Cellules Vero, Chloroquine (pharmacologie), Chlorure d'ammonium (pharmacologie), Glycoprotéine de spicule des coronavirus, Glycoprotéines membranaires (métabolisme), Glycosylation, Peptidyl-Dipeptidase A (métabolisme), Protéines de l'enveloppe virale (métabolisme), Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (métabolisme), Syndrome respiratoire aigu sévère (traitement médicamenteux), Syndrome respiratoire aigu sévère (virologie), Technique d'immunofluorescence indirecte, Virus du SRAS ().
- MESH :
- métabolisme : Glycoprotéines membranaires, Peptidyl-Dipeptidase A, Protéines de l'enveloppe virale, Syndrome respiratoire aigu sévère.
- pharmacologie : Antiviraux, Chloroquine, Chlorure d'ammonium.
- traitement médicamenteux : Syndrome respiratoire aigu sévère.
- virologie : Syndrome respiratoire aigu sévère.
- Animaux, Cellules Vero, Glycoprotéine de spicule des coronavirus, Glycosylation, Syndrome respiratoire aigu sévère, Technique d'immunofluorescence indirecte, Virus du SRAS.
English descriptors
- KwdEn :
- Ammonium Chloride (pharmacology), Animals, Antiviral Agents (pharmacology), Chlorocebus aethiops, Chloroquine (pharmacology), Fluorescent Antibody Technique, Indirect, Glycosylation, Membrane Glycoproteins (metabolism), Peptidyl-Dipeptidase A (metabolism), SARS Virus (drug effects), Severe Acute Respiratory Syndrome (drug therapy), Severe Acute Respiratory Syndrome (metabolism), Severe Acute Respiratory Syndrome (prevention & control), Severe Acute Respiratory Syndrome (virology), Spike Glycoprotein, Coronavirus, Vero Cells, Viral Envelope Proteins (metabolism).
- MESH :
- chemical , metabolism : Membrane Glycoproteins, Peptidyl-Dipeptidase A, Viral Envelope Proteins.
- chemical , pharmacology : Ammonium Chloride, Antiviral Agents, Chloroquine.
- drug effects : SARS Virus.
- drug therapy : Severe Acute Respiratory Syndrome.
- metabolism : Severe Acute Respiratory Syndrome.
- prevention & control : Severe Acute Respiratory Syndrome.
- virology : Severe Acute Respiratory Syndrome.
- Animals, Chlorocebus aethiops, Fluorescent Antibody Technique, Indirect, Glycosylation, Spike Glycoprotein, Coronavirus, Vero Cells.
Abstract
Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.
DOI: 10.1186/1743-422X-2-69
PubMed: 16115318
Affiliations:
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pubmed:16115318Le document en format XML
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<term>Fluorescent Antibody Technique, Indirect</term>
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<front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.</div>
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