SrasV1, Main, Merge, bibRecord, 005195

Detection of severe acute respiratory syndrome coronavirus RNA in plasma during the course of infection

Identifieur interne : 005195 ( Main/Merge ); précédent : 005194; suivant : 005196

Detection of severe acute respiratory syndrome coronavirus RNA in plasma during the course of infection

Auteurs : Wei-Kung Wang [Taïwan] ; Chi-Tai Fang [Taïwan] ; Hui-Ling Chen [Taïwan] ; Chao-Fu Yang [Taïwan] ; Yee-Chun Chen [Taïwan] ; Mei-Ling Chen [Taïwan] ; Shey-Ying Chen [Taïwan] ; Jyh-Yuan Yang [Taïwan] ; Jih-Hui Lin [Taïwan] ; Pan-Chyr Yang [Taïwan] ; Shan-Chwen Chang [Taïwan]

Source :

Journal of clinical microbiology : (Print) [ 0095-1137 ] ; 2005.

RBID : Pascal:05-0143513

Descripteurs français

Pascal (Inist)
- Coronavirus, Détection, Microbiologie, Syndrome respiratoire aigu sévère.

English descriptors

KwdEn :
- Coronavirus, Detection, Microbiology, Severe acute respiratory syndrome.

Abstract

We examined severe acute respiratory syndrome-associated coronavirus (SARS-CoV) RNA in plasma of 32 patients (probable SARS cases) by a quantitative real-time reverse transcription-PCR assay and reported that the highest detection rate, 75%, was found between day 5 and day 7 of illness, followed by rates of 64, 50, and 38% found between day 8 and day 11, day 2 and day 4, and day 12 and day 16, respectively. Analysis of sequential SARS-CoV load in plasma from six cases revealed different patterns of viremia, with the peak between day 4 and day 8. Our findings of the high detection rate of SARS-CoV RNA in plasma before day 11, together with the relative convenience of collecting and handling plasma, suggest that plasma can be used for early diagnosis of SARS.

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Pascal:05-0143513

Le document en format XML

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<front><div type="abstract" xml:lang="en">We examined severe acute respiratory syndrome-associated coronavirus (SARS-CoV) RNA in plasma of 32 patients (probable SARS cases) by a quantitative real-time reverse transcription-PCR assay and reported that the highest detection rate, 75%, was found between day 5 and day 7 of illness, followed by rates of 64, 50, and 38% found between day 8 and day 11, day 2 and day 4, and day 12 and day 16, respectively. Analysis of sequential SARS-CoV load in plasma from six cases revealed different patterns of viremia, with the peak between day 4 and day 8. Our findings of the high detection rate of SARS-CoV RNA in plasma before day 11, together with the relative convenience of collecting and handling plasma, suggest that plasma can be used for early diagnosis of SARS.</div>
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Detection of severe acute respiratory syndrome coronavirus RNA in plasma during the course of infection

Detection of severe acute respiratory syndrome coronavirus RNA in plasma during the course of infection

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Descripteurs français

English descriptors

Abstract

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