SrasV1, Main, Merge, bibRecord, 005166

First external quality assurance of antibody diagnostic for SARS-new coronavirus

Identifieur interne : 005166 ( Main/Merge ); précédent : 005165; suivant : 005167

First external quality assurance of antibody diagnostic for SARS-new coronavirus

Auteurs : Matthias Niedrig [Allemagne] ; Katrin Leitmeyer [Allemagne, Suisse] ; Wilina Lim [Hong Kong] ; Malik Peiris [Hong Kong] ; John S. Mackenzie [Suisse, Australie] ; Maria Zambon [Royaume-Uni]

Source :

Journal of clinical virology [ 1386-6532 ] ; 2005.

RBID : Pascal:05-0385590

Descripteurs français

Pascal (Inist)
- Virus syndrome respiratoire aigu sévère, Anticorps, Microbiologie, Virologie, Syndrome respiratoire aigu sévère.

English descriptors

KwdEn :
- Antibody, Microbiology, Severe acute respiratory syndrome, Severe acute respiratory syndrome virus, Virology.

Abstract

To confirm an infection with the new coronavirus (SARS-CoV) causing the severe acute respiratory syndrome (SARS) diagnostic assays for detection of SARS-CoV specific antibody are necessary. To evaluate the diagnostic performance of laboratories an external quality assurance (EQA) study was performed in 2004. Participating laboratories (9/20) correctly detected anti-SARS antibodies in serum samples without false positive results in an immunofluorescence assay. In contrast, only 4/13 laboratories detected most of the anti-SARS antibody positive samples without false positive results using enzyme immunoassays (EIA) and/or immunoblot. The overall results clearly demonstrate that serological diagnosis of SARS-CoV remains at an early stage of development, with further technical improvements required, particularly with respect to the use of SARS specific ElAs.

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Pascal:05-0385590

Le document en format XML

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<author><name sortKey="Niedrig, Matthias" sort="Niedrig, Matthias" uniqKey="Niedrig M" first="Matthias" last="Niedrig">Matthias Niedrig</name>
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<front><div type="abstract" xml:lang="en">To confirm an infection with the new coronavirus (SARS-CoV) causing the severe acute respiratory syndrome (SARS) diagnostic assays for detection of SARS-CoV specific antibody are necessary. To evaluate the diagnostic performance of laboratories an external quality assurance (EQA) study was performed in 2004. Participating laboratories (9/20) correctly detected anti-SARS antibodies in serum samples without false positive results in an immunofluorescence assay. In contrast, only 4/13 laboratories detected most of the anti-SARS antibody positive samples without false positive results using enzyme immunoassays (EIA) and/or immunoblot. The overall results clearly demonstrate that serological diagnosis of SARS-CoV remains at an early stage of development, with further technical improvements required, particularly with respect to the use of SARS specific ElAs.</div>
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First external quality assurance of antibody diagnostic for SARS-new coronavirus

First external quality assurance of antibody diagnostic for SARS-new coronavirus

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri