The severe acute respiratory syndrome (SARS)
Identifieur interne : 004821 ( Main/Merge ); précédent : 004820; suivant : 004822The severe acute respiratory syndrome (SARS)
Auteurs : Samson S. Y. Wong ; K. Y. YuenSource :
- Journal of Neurovirology [ 1355-0284 ] ; 2005.
Descripteurs français
- KwdFr :
- Animaux, Antiviraux (usage thérapeutique), Facteurs de risque, Facteurs immunologiques (usage thérapeutique), Flambées de maladies, Humains, Immunisation, Maladies transmissibles émergentes (), Maladies transmissibles émergentes (diagnostic), Maladies transmissibles émergentes (épidémiologie), Modèles animaux de maladie humaine, Santé mondiale, Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (diagnostic), Syndrome respiratoire aigu sévère (épidémiologie), Transports, Vaccins antiviraux (administration et posologie), Virus du SRAS (isolement et purification), Virus du SRAS (physiologie).
- MESH :
- administration et posologie : Vaccins antiviraux.
- diagnostic : Maladies transmissibles émergentes, Syndrome respiratoire aigu sévère.
- isolement et purification : Virus du SRAS.
- physiologie : Virus du SRAS.
- usage thérapeutique : Antiviraux, Facteurs immunologiques.
- épidémiologie : Maladies transmissibles émergentes, Syndrome respiratoire aigu sévère.
- Animaux, Facteurs de risque, Flambées de maladies, Humains, Immunisation, Maladies transmissibles émergentes, Modèles animaux de maladie humaine, Santé mondiale, Syndrome respiratoire aigu sévère, Transports.
English descriptors
- KwdEn :
- Animals, Antiviral Agents (therapeutic use), Communicable Diseases, Emerging (diagnosis), Communicable Diseases, Emerging (epidemiology), Communicable Diseases, Emerging (therapy), Disease Models, Animal, Disease Outbreaks, Global Health, Humans, Immunization, Immunologic Factors (therapeutic use), Risk Factors, SARS Virus (isolation & purification), SARS Virus (physiology), Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (therapy), Transportation, Viral Vaccines (administration & dosage).
- MESH :
- chemical , administration & dosage : Viral Vaccines.
- chemical , therapeutic use : Antiviral Agents, Immunologic Factors.
- diagnosis : Communicable Diseases, Emerging, Severe Acute Respiratory Syndrome.
- epidemiology : Communicable Diseases, Emerging, Severe Acute Respiratory Syndrome.
- isolation & purification : SARS Virus.
- physiology : SARS Virus.
- therapy : Communicable Diseases, Emerging, Severe Acute Respiratory Syndrome.
- Animals, Disease Models, Animal, Disease Outbreaks, Global Health, Humans, Immunization, Risk Factors, Transportation.
Abstract
The world was shocked in early 2003 when a pandemic of severe acute respiratory syndrome (SARS) was imminent. The outbreak of this novel disease, caused by a novel coronavirus (the SARS-coronavirus), hit hardest in the Asian Pacific region, though eventually it spread to five continents. The speed of the spread of the SARS epidemic was unprecedented due to the highly efficient intercontinental transportation. An international collaborative effort through the World Health Organization (WHO) has helped to identify the aetiological agent about 1 month after the onset of the epidemic. The power of molecular biology and bioinformatics has enabled the complete decoding of the viral genome within weeks. Over 1000 publications on the phylogeny, epidemiology, genomics, laboratory diagnostics, antiviral, immunization, pathogenesis, clinical disease, and management accumulated within just 1 year. Although the exact animal reservoir of virus and how it evolved into a human pathogen are still obscure, accurate diagnosis and epidemiological control of the disease are now possible. This article reviews what is currently known about the virus and the disease.
Url:
DOI: 10.1080/13550280500187724
PubMed: 16287687
PubMed Central: 7095431
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PMC:7095431Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>The world was shocked in early 2003 when a pandemic of severe acute respiratory syndrome (SARS) was imminent. The outbreak of this novel disease, caused by a novel coronavirus (the SARS-coronavirus), hit hardest in the Asian Pacific region, though eventually it spread to five continents. The speed of the spread of the SARS epidemic was unprecedented due to the highly efficient intercontinental transportation. An international collaborative effort through the World Health Organization (WHO) has helped to identify the aetiological agent about 1 month after the onset of the epidemic. The power of molecular biology and bioinformatics has enabled the complete decoding of the viral genome within weeks. Over 1000 publications on the phylogeny, epidemiology, genomics, laboratory diagnostics, antiviral, immunization, pathogenesis, clinical disease, and management accumulated within just 1 year. Although the exact animal reservoir of virus and how it evolved into a human pathogen are still obscure, accurate diagnosis and epidemiological control of the disease are now possible. This article reviews what is currently known about the virus and the disease.</p>
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