The severe acute respiratory syndrome (SARS)
Identifieur interne : 000546 ( Pmc/Curation ); précédent : 000545; suivant : 000547The severe acute respiratory syndrome (SARS)
Auteurs : Samson S. Y. Wong ; K. Y. YuenSource :
- Journal of Neurovirology [ 1355-0284 ] ; 2005.
Abstract
The world was shocked in early 2003 when a pandemic of severe acute respiratory syndrome (SARS) was imminent. The outbreak of this novel disease, caused by a novel coronavirus (the SARS-coronavirus), hit hardest in the Asian Pacific region, though eventually it spread to five continents. The speed of the spread of the SARS epidemic was unprecedented due to the highly efficient intercontinental transportation. An international collaborative effort through the World Health Organization (WHO) has helped to identify the aetiological agent about 1 month after the onset of the epidemic. The power of molecular biology and bioinformatics has enabled the complete decoding of the viral genome within weeks. Over 1000 publications on the phylogeny, epidemiology, genomics, laboratory diagnostics, antiviral, immunization, pathogenesis, clinical disease, and management accumulated within just 1 year. Although the exact animal reservoir of virus and how it evolved into a human pathogen are still obscure, accurate diagnosis and epidemiological control of the disease are now possible. This article reviews what is currently known about the virus and the disease.
Url:
DOI: 10.1080/13550280500187724
PubMed: 16287687
PubMed Central: 7095431
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<front><div type="abstract" xml:lang="en"><p>The world was shocked in early 2003 when a pandemic of severe acute respiratory syndrome (SARS) was imminent. The outbreak of this novel disease, caused by a novel coronavirus (the SARS-coronavirus), hit hardest in the Asian Pacific region, though eventually it spread to five continents. The speed of the spread of the SARS epidemic was unprecedented due to the highly efficient intercontinental transportation. An international collaborative effort through the World Health Organization (WHO) has helped to identify the aetiological agent about 1 month after the onset of the epidemic. The power of molecular biology and bioinformatics has enabled the complete decoding of the viral genome within weeks. Over 1000 publications on the phylogeny, epidemiology, genomics, laboratory diagnostics, antiviral, immunization, pathogenesis, clinical disease, and management accumulated within just 1 year. Although the exact animal reservoir of virus and how it evolved into a human pathogen are still obscure, accurate diagnosis and epidemiological control of the disease are now possible. This article reviews what is currently known about the virus and the disease.</p>
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<pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Neurovirol</journal-id>
<journal-id journal-id-type="iso-abbrev">J. Neurovirol</journal-id>
<journal-title-group><journal-title>Journal of Neurovirology</journal-title>
</journal-title-group>
<issn pub-type="ppub">1355-0284</issn>
<issn pub-type="epub">1538-2443</issn>
<publisher><publisher-name>Springer-Verlag</publisher-name>
<publisher-loc>New York</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">16287687</article-id>
<article-id pub-id-type="pmc">7095431</article-id>
<article-id pub-id-type="publisher-id">110500455</article-id>
<article-id pub-id-type="doi">10.1080/13550280500187724</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Review</subject>
</subj-group>
</article-categories>
<title-group><article-title>The severe acute respiratory syndrome (SARS)</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Wong</surname>
<given-names>Samson S. Y.</given-names>
</name>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Yuen</surname>
<given-names>K. Y.</given-names>
</name>
<address><email>kyyuen@hkucc.hku.hk</email>
</address>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.415550.0</institution-id>
<institution-id institution-id-type="ISNI">0000000417644144</institution-id>
<institution>Department of Microbiology,</institution>
<institution>The University of Hong Kong, University Pathology Building, Queen Mary Hospital,</institution>
</institution-wrap>
Pokfulam Road, Hong Kong</aff>
</contrib-group>
<pub-date pub-type="ppub"><year>2005</year>
</pub-date>
<volume>11</volume>
<issue>5</issue>
<fpage>455</fpage>
<lpage>468</lpage>
<permissions><copyright-statement>© Journal of NeuroVirology, Inc. 2005</copyright-statement>
<license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p>
</license>
</permissions>
<abstract id="Abs1"><p>The world was shocked in early 2003 when a pandemic of severe acute respiratory syndrome (SARS) was imminent. The outbreak of this novel disease, caused by a novel coronavirus (the SARS-coronavirus), hit hardest in the Asian Pacific region, though eventually it spread to five continents. The speed of the spread of the SARS epidemic was unprecedented due to the highly efficient intercontinental transportation. An international collaborative effort through the World Health Organization (WHO) has helped to identify the aetiological agent about 1 month after the onset of the epidemic. The power of molecular biology and bioinformatics has enabled the complete decoding of the viral genome within weeks. Over 1000 publications on the phylogeny, epidemiology, genomics, laboratory diagnostics, antiviral, immunization, pathogenesis, clinical disease, and management accumulated within just 1 year. Although the exact animal reservoir of virus and how it evolved into a human pathogen are still obscure, accurate diagnosis and epidemiological control of the disease are now possible. This article reviews what is currently known about the virus and the disease.</p>
</abstract>
<kwd-group xml:lang="en"><title>Keywords</title>
<kwd>coronavirus</kwd>
<kwd>pathology</kwd>
<kwd>SARS</kwd>
<kwd>severe acute respiratory syndrome</kwd>
<kwd>vaccine</kwd>
<kwd>virology</kwd>
</kwd-group>
<custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name>
<meta-value>© Journal of NeuroVirology, Inc. 2005</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
</record>
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