SrasV1, Main, Merge, bibRecord, 003624

Antiviral Effects of Glycyrrhiza species

Identifieur interne : 003624 ( Main/Merge ); précédent : 003623; suivant : 003625

Antiviral Effects of Glycyrrhiza species

Auteurs : Cristina Fiore [Italie] ; Michael Eisenhut [Royaume-Uni] ; Rea Krausse [Allemagne] ; Eugenio Ragazzi [Italie] ; Donatella Pellati [Italie] ; Decio Armanini [Italie] ; Jens Bielenberg [Allemagne]

Source :

PTR. Phytotherapy research [ 0951-418X ] ; 2008.

RBID : Pascal:08-0153199

Descripteurs français

Pascal (Inist)
- Antiviral, Espèce, Réglisse, Acide glycyrrhizique, Enoxolone, Grippe, Hépatite, Relation structure activité, Pharmacognosie, Plante médicinale, Glycyrrhiza glabra, Origine végétale, Leguminosae, Saponine, Dérivé de l'oléanane, Acide uronique, Antiinflammatoire, Glycoside, Triterpène, Terpénoïde.
Wicri :
- topic : Plante médicinale.

English descriptors

KwdEn :
- Antiinflammatory agent, Antiviral, Enoxolone, Glycoside, Glycyrrhiza glabra, Glycyrrhizic acid, Hepatitis, Influenza, Leguminosae, Licorice, Medicinal plant, Oleanane derivatives, Pharmacognosy, Plant origin, Saponin, Species, Structure activity relation, Terpenoid, Triterpene, Uronic acid.

Abstract

Historical sources for the use of Glycyrrhiza species include ancient manuscripts from China, India and Greece. They all mention its use for symptoms of viral respiratory tract infections and hepatitis. Randomized controlled trials confirmed that the Glycyrrhiza glabra derived compound glycyrrhizin and its derivatives reduced hepatocellular damage in chronic hepatitis B and C. In hepatitis C virus-induced cirrhosis the risk of hepatocellular carcinoma was reduced. Animal studies demonstrated a reduction of mortality and viral activity in herpes simplex virus encephalitis and influenza A virus pneumonia. In vitro studies revealed antiviral activity against HIV-1, SARS related coronavirus, respiratory syncytial virus, arboviruses, vaccinia virus and vesicular stomatitis virus. Mechanisms for antiviral activity of Glycyrrhiza spp. include reduced transport to the membrane and sialylation of hepatitis B virus surface antigen, reduction of membrane fluidity leading to inhibition of fusion of the viral membrane of HIV-1 with the cell, induction of interferon gamma in T-cells, inhibition of phosphorylating enzymes in vesicular stomatitis virus infection and reduction of viral latency. Future research needs to explore the potency of compounds derived from licorice in prevention and treatment of influenza A virus pneumonia and as an adjuvant treatment in patients infected with HIV resistant to antiretroviral drugs.

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Le document en format XML

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<author><name sortKey="Fiore, Cristina" sort="Fiore, Cristina" uniqKey="Fiore C" first="Cristina" last="Fiore">Cristina Fiore</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Antiviral Effects of Glycyrrhiza species</title>
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<sZ>3 aut.</sZ>
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<author><name sortKey="Pellati, Donatella" sort="Pellati, Donatella" uniqKey="Pellati D" first="Donatella" last="Pellati">Donatella Pellati</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Medical and Surgical Sciences-Endocrinology, University of Padua</s1>
<s2>Padova</s2>
<s3>ITA</s3>
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<author><name sortKey="Armanini, Decio" sort="Armanini, Decio" uniqKey="Armanini D" first="Decio" last="Armanini">Decio Armanini</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Medical and Surgical Sciences-Endocrinology, University of Padua</s1>
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<s3>ITA</s3>
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<sZ>5 aut.</sZ>
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<author><name sortKey="Bielenberg, Jens" sort="Bielenberg, Jens" uniqKey="Bielenberg J" first="Jens" last="Bielenberg">Jens Bielenberg</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Raphael-Apotheke, Bahnhofstr.53</s1>
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<wicri:noRegion>25364 Westerhorn</wicri:noRegion>
<wicri:noRegion>Bahnhofstr.53</wicri:noRegion>
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<series><title level="j" type="main">PTR. Phytotherapy research</title>
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<seriesStmt><title level="j" type="main">PTR. Phytotherapy research</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiinflammatory agent</term>
<term>Antiviral</term>
<term>Enoxolone</term>
<term>Glycoside</term>
<term>Glycyrrhiza glabra</term>
<term>Glycyrrhizic acid</term>
<term>Hepatitis</term>
<term>Influenza</term>
<term>Leguminosae</term>
<term>Licorice</term>
<term>Medicinal plant</term>
<term>Oleanane derivatives</term>
<term>Pharmacognosy</term>
<term>Plant origin</term>
<term>Saponin</term>
<term>Species</term>
<term>Structure activity relation</term>
<term>Terpenoid</term>
<term>Triterpene</term>
<term>Uronic acid</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Antiviral</term>
<term>Espèce</term>
<term>Réglisse</term>
<term>Acide glycyrrhizique</term>
<term>Enoxolone</term>
<term>Grippe</term>
<term>Hépatite</term>
<term>Relation structure activité</term>
<term>Pharmacognosie</term>
<term>Plante médicinale</term>
<term>Glycyrrhiza glabra</term>
<term>Origine végétale</term>
<term>Leguminosae</term>
<term>Saponine</term>
<term>Dérivé de l'oléanane</term>
<term>Acide uronique</term>
<term>Antiinflammatoire</term>
<term>Glycoside</term>
<term>Triterpène</term>
<term>Terpénoïde</term>
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<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Plante médicinale</term>
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<front><div type="abstract" xml:lang="en">Historical sources for the use of Glycyrrhiza species include ancient manuscripts from China, India and Greece. They all mention its use for symptoms of viral respiratory tract infections and hepatitis. Randomized controlled trials confirmed that the Glycyrrhiza glabra derived compound glycyrrhizin and its derivatives reduced hepatocellular damage in chronic hepatitis B and C. In hepatitis C virus-induced cirrhosis the risk of hepatocellular carcinoma was reduced. Animal studies demonstrated a reduction of mortality and viral activity in herpes simplex virus encephalitis and influenza A virus pneumonia. In vitro studies revealed antiviral activity against HIV-1, SARS related coronavirus, respiratory syncytial virus, arboviruses, vaccinia virus and vesicular stomatitis virus. Mechanisms for antiviral activity of Glycyrrhiza spp. include reduced transport to the membrane and sialylation of hepatitis B virus surface antigen, reduction of membrane fluidity leading to inhibition of fusion of the viral membrane of HIV-1 with the cell, induction of interferon gamma in T-cells, inhibition of phosphorylating enzymes in vesicular stomatitis virus infection and reduction of viral latency. Future research needs to explore the potency of compounds derived from licorice in prevention and treatment of influenza A virus pneumonia and as an adjuvant treatment in patients infected with HIV resistant to antiretroviral drugs.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Italie</li>
<li>Royaume-Uni</li>
</country>
</list>
<tree><country name="Italie"><noRegion><name sortKey="Fiore, Cristina" sort="Fiore, Cristina" uniqKey="Fiore C" first="Cristina" last="Fiore">Cristina Fiore</name>
</noRegion>
<name sortKey="Armanini, Decio" sort="Armanini, Decio" uniqKey="Armanini D" first="Decio" last="Armanini">Decio Armanini</name>
<name sortKey="Pellati, Donatella" sort="Pellati, Donatella" uniqKey="Pellati D" first="Donatella" last="Pellati">Donatella Pellati</name>
<name sortKey="Ragazzi, Eugenio" sort="Ragazzi, Eugenio" uniqKey="Ragazzi E" first="Eugenio" last="Ragazzi">Eugenio Ragazzi</name>
</country>
<country name="Royaume-Uni"><noRegion><name sortKey="Eisenhut, Michael" sort="Eisenhut, Michael" uniqKey="Eisenhut M" first="Michael" last="Eisenhut">Michael Eisenhut</name>
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<country name="Allemagne"><noRegion><name sortKey="Krausse, Rea" sort="Krausse, Rea" uniqKey="Krausse R" first="Rea" last="Krausse">Rea Krausse</name>
</noRegion>
<name sortKey="Bielenberg, Jens" sort="Bielenberg, Jens" uniqKey="Bielenberg J" first="Jens" last="Bielenberg">Jens Bielenberg</name>
</country>
</tree>
</affiliations>
</record>

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Antiviral Effects of Glycyrrhiza species

Antiviral Effects of Glycyrrhiza species

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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