ORF8-Related Genetic Evidence for Chinese Horseshoe Bats as the Source of Human Severe Acute Respiratory Syndrome Coronavirus
Identifieur interne : 001273 ( Main/Exploration ); précédent : 001272; suivant : 001274ORF8-Related Genetic Evidence for Chinese Horseshoe Bats as the Source of Human Severe Acute Respiratory Syndrome Coronavirus
Auteurs : Zhiqiang Wu ; Li Yang ; Xianwen Ren ; Junpeng Zhang ; Fan Yang ; Shuyi Zhang [République populaire de Chine] ; Qi JinSource :
- The Journal of Infectious Diseases [ 0022-1899 ] ; 2015.
Descripteurs français
- KwdFr :
- ARN viral (génétique), Analyse de regroupements, Analyse de séquence d'ADN, Animaux, Chine, Chiroptera (virologie), Données de séquences moléculaires, Génotype, Humains, Protéines de la matrice virale (génétique), Similitude de séquences, Virus du SRAS (), Virus du SRAS (génétique), Évolution moléculaire.
- MESH :
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : RNA, Viral, Viral Matrix Proteins.
- geographic : China.
- classification : SARS Virus.
- genetics : SARS Virus.
- virology : Chiroptera.
- Animals, Cluster Analysis, Evolution, Molecular, Genotype, Humans, Molecular Sequence Data, Sequence Analysis, DNA, Sequence Homology.
Abstract
Several lineage B betacoronaviruses termed severe acute respiratory syndrome (SARS)–like CoVs (SL-CoVs) were identified from
Url:
DOI: 10.1093/infdis/jiv476
PubMed: 26433221
PubMed Central: 7107392
Affiliations:
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Le document en format XML
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<series><title level="j">The Journal of Infectious Diseases</title>
<idno type="ISSN">0022-1899</idno>
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<term>China</term>
<term>Chiroptera (virology)</term>
<term>Cluster Analysis</term>
<term>Evolution, Molecular</term>
<term>Genotype</term>
<term>Humans</term>
<term>Molecular Sequence Data</term>
<term>RNA, Viral (genetics)</term>
<term>SARS Virus (classification)</term>
<term>SARS Virus (genetics)</term>
<term>Sequence Analysis, DNA</term>
<term>Sequence Homology</term>
<term>Viral Matrix Proteins (genetics)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (génétique)</term>
<term>Analyse de regroupements</term>
<term>Analyse de séquence d'ADN</term>
<term>Animaux</term>
<term>Chine</term>
<term>Chiroptera (virologie)</term>
<term>Données de séquences moléculaires</term>
<term>Génotype</term>
<term>Humains</term>
<term>Protéines de la matrice virale (génétique)</term>
<term>Similitude de séquences</term>
<term>Virus du SRAS ()</term>
<term>Virus du SRAS (génétique)</term>
<term>Évolution moléculaire</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>RNA, Viral</term>
<term>Viral Matrix Proteins</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>China</term>
</keywords>
<keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>SARS Virus</term>
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<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term>
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<term>Cluster Analysis</term>
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<term>Sequence Analysis, DNA</term>
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<term>Données de séquences moléculaires</term>
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<term>Similitude de séquences</term>
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<front><div type="abstract" xml:lang="en"><title>Abstract</title>
<p>Several lineage B betacoronaviruses termed severe acute respiratory syndrome (SARS)–like CoVs (SL-CoVs) were identified from <italic>Rhinolophus</italic>
bats in China. These viruses are characterized by a set of unique accessory open reading frames (ORFs) that are located between the M and N genes. Among unique accessory ORFs, ORF8 is most hypervariable. In this study, the ORF8s of all SL-CoVs were classified into 3 types, and, for the first time, it was found that very few SL-CoVs from <italic>Rhinolophus sinicus</italic>
have ORF8s that are identical to that of human SARS-CoV. This finding provides new genetic evidence for Chinese horseshoe bats as the source of human SARS-CoV.</p>
</div>
</front>
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<name sortKey="Ren, Xianwen" sort="Ren, Xianwen" uniqKey="Ren X" first="Xianwen" last="Ren">Xianwen Ren</name>
<name sortKey="Wu, Zhiqiang" sort="Wu, Zhiqiang" uniqKey="Wu Z" first="Zhiqiang" last="Wu">Zhiqiang Wu</name>
<name sortKey="Yang, Fan" sort="Yang, Fan" uniqKey="Yang F" first="Fan" last="Yang">Fan Yang</name>
<name sortKey="Yang, Li" sort="Yang, Li" uniqKey="Yang L" first="Li" last="Yang">Li Yang</name>
<name sortKey="Zhang, Junpeng" sort="Zhang, Junpeng" uniqKey="Zhang J" first="Junpeng" last="Zhang">Junpeng Zhang</name>
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<country name="République populaire de Chine"><noRegion><name sortKey="Zhang, Shuyi" sort="Zhang, Shuyi" uniqKey="Zhang S" first="Shuyi" last="Zhang">Shuyi Zhang</name>
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