Characterisation of novel microRNAs in the Black flying fox (Pteropus alecto) by deep sequencing.
Identifieur interne : 001691 ( Main/Exploration ); précédent : 001690; suivant : 001692Characterisation of novel microRNAs in the Black flying fox (Pteropus alecto) by deep sequencing.
Auteurs : Christopher Cowled [Australie] ; Cameron R. Stewart ; Vladimir A. Likic ; Marc R. Friedl Nder ; Mary Tachedjian ; Kristie A. Jenkins ; Mark L. Tizard ; Pauline Cottee ; Glenn A. Marsh ; Peng Zhou ; Michelle L. Baker ; Andrew G. Bean ; Lin-Fa WangSource :
- BMC genomics [ 1471-2164 ] ; 2014.
Descripteurs français
- KwdFr :
- Analyse de séquence d'ARN, Animaux, Annotation de séquence moléculaire, Chiroptera (génétique), Données de séquences moléculaires, Famille multigénique, Gene Ontology, Interférence par ARN, Introns, Mâle, Similitude de séquences d'acides nucléiques, Sites de fixation, Séquence nucléotidique, Séquences répétées inversées, Séquençage nucléotidique à haut débit, microARN (génétique).
- MESH :
- génétique : Chiroptera, microARN.
- Analyse de séquence d'ARN, Animaux, Annotation de séquence moléculaire, Données de séquences moléculaires, Famille multigénique, Gene Ontology, Interférence par ARN, Introns, Mâle, Similitude de séquences d'acides nucléiques, Sites de fixation, Séquence nucléotidique, Séquences répétées inversées, Séquençage nucléotidique à haut débit.
English descriptors
- KwdEn :
- Animals, Base Sequence, Binding Sites, Chiroptera (genetics), Gene Ontology, High-Throughput Nucleotide Sequencing, Introns, Inverted Repeat Sequences, Male, MicroRNAs (genetics), Molecular Sequence Annotation, Molecular Sequence Data, Multigene Family, RNA Interference, Sequence Analysis, RNA, Sequence Homology, Nucleic Acid.
- MESH :
- chemical , genetics : MicroRNAs.
- genetics : Chiroptera.
- Animals, Base Sequence, Binding Sites, Gene Ontology, High-Throughput Nucleotide Sequencing, Introns, Inverted Repeat Sequences, Male, Molecular Sequence Annotation, Molecular Sequence Data, Multigene Family, RNA Interference, Sequence Analysis, RNA, Sequence Homology, Nucleic Acid.
Abstract
Bats are a major source of new and emerging viral diseases. Despite the fact that bats carry and shed highly pathogenic viruses including Ebola, Nipah and SARS, they rarely display clinical symptoms of infection. Host factors influencing viral replication are poorly understood in bats and are likely to include both pre- and post-transcriptional regulatory mechanisms. MicroRNAs are a major mechanism of post-transcriptional gene regulation, however very little is known about them in bats.
DOI: 10.1186/1471-2164-15-682
PubMed: 25128405
Affiliations:
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Le document en format XML
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<term>Binding Sites</term>
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<term>Introns</term>
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<term>Sites de fixation</term>
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<front><div type="abstract" xml:lang="en">Bats are a major source of new and emerging viral diseases. Despite the fact that bats carry and shed highly pathogenic viruses including Ebola, Nipah and SARS, they rarely display clinical symptoms of infection. Host factors influencing viral replication are poorly understood in bats and are likely to include both pre- and post-transcriptional regulatory mechanisms. MicroRNAs are a major mechanism of post-transcriptional gene regulation, however very little is known about them in bats.</div>
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