Residue analysis of a CTL epitope of SARS-CoV spike protein by IFN-gamma production and bioinformatics prediction
Identifieur interne : 001C71 ( Main/Exploration ); précédent : 001C70; suivant : 001C72Residue analysis of a CTL epitope of SARS-CoV spike protein by IFN-gamma production and bioinformatics prediction
Auteurs : Jun Huang [République populaire de Chine] ; Yingnan Cao [République populaire de Chine] ; Xianzhang Bu [République populaire de Chine] ; Changyou Wu [République populaire de Chine]Source :
- BMC Immunology [ 1471-2172 ] ; 2012.
Descripteurs français
- KwdFr :
- Analyse de séquence de protéine, Animaux, Biologie informatique, Cartographie épitopique (), Cellules cultivées, Déterminants antigéniques des lymphocytes T (immunologie), Déterminants antigéniques des lymphocytes T (métabolisme), Femelle, Fragments peptidiques (immunologie), Fragments peptidiques (métabolisme), Glycoprotéine de spicule des coronavirus, Glycoprotéines membranaires (immunologie), Glycoprotéines membranaires (métabolisme), Interféron gamma (métabolisme), Liaison aux protéines, Lymphocytes T cytotoxiques (immunologie), Protéines de l'enveloppe virale (immunologie), Protéines de l'enveloppe virale (métabolisme), Souris, Souris de lignée BALB C, Syndrome respiratoire aigu sévère (immunologie), Test ELISpot, Virus du SRAS (immunologie).
- MESH :
- immunologie : Déterminants antigéniques des lymphocytes T, Fragments peptidiques, Glycoprotéines membranaires, Lymphocytes T cytotoxiques, Protéines de l'enveloppe virale, Syndrome respiratoire aigu sévère, Virus du SRAS.
- métabolisme : Déterminants antigéniques des lymphocytes T, Fragments peptidiques, Glycoprotéines membranaires, Interféron gamma, Protéines de l'enveloppe virale.
- Analyse de séquence de protéine, Animaux, Biologie informatique, Cartographie épitopique, Cellules cultivées, Femelle, Glycoprotéine de spicule des coronavirus, Liaison aux protéines, Souris, Souris de lignée BALB C, Test ELISpot.
English descriptors
- KwdEn :
- Animals, Cells, Cultured, Computational Biology, Enzyme-Linked Immunospot Assay, Epitope Mapping (methods), Epitopes, T-Lymphocyte (immunology), Epitopes, T-Lymphocyte (metabolism), Female, Interferon-gamma (metabolism), Membrane Glycoproteins (immunology), Membrane Glycoproteins (metabolism), Mice, Mice, Inbred BALB C, Peptide Fragments (immunology), Peptide Fragments (metabolism), Protein Binding, SARS Virus (immunology), Sequence Analysis, Protein, Severe Acute Respiratory Syndrome (immunology), Spike Glycoprotein, Coronavirus, T-Lymphocytes, Cytotoxic (immunology), Viral Envelope Proteins (immunology), Viral Envelope Proteins (metabolism).
- MESH :
- chemical , immunology : Epitopes, T-Lymphocyte, Membrane Glycoproteins, Peptide Fragments, Viral Envelope Proteins.
- chemical , metabolism : Epitopes, T-Lymphocyte, Interferon-gamma, Membrane Glycoproteins, Peptide Fragments, Viral Envelope Proteins.
- immunology : SARS Virus, Severe Acute Respiratory Syndrome, T-Lymphocytes, Cytotoxic.
- methods : Epitope Mapping.
- Animals, Cells, Cultured, Computational Biology, Enzyme-Linked Immunospot Assay, Female, Mice, Mice, Inbred BALB C, Protein Binding, Sequence Analysis, Protein, Spike Glycoprotein, Coronavirus.
Abstract
Severe acute respiratory syndrome (SARS) is an emerging infectious disease caused by the novel coronavirus SARS-CoV. The T cell epitopes of the SARS CoV spike protein are well known, but no systematic evaluation of the functional and structural roles of each residue has been reported for these antigenic epitopes. Analysis of the functional importance of side-chains by mutational study may exaggerate the effect by imposing a structural disturbance or an unusual steric, electrostatic or hydrophobic interaction.
We demonstrated that N50 could induce significant IFN-gamma response from SARS-CoV S DNA immunized mice splenocytes by the means of ELISA, ELISPOT and FACS. Moreover, S366-374 was predicted to be an optimal epitope by bioinformatics tools: ANN, SMM, ARB and BIMAS, and confirmed by IFN-gamma response induced by a series of S358-374-derived peptides. Furthermore, each of S366-374 was replaced by alanine (A), lysine (K) or aspartic acid (D), respectively. ANN was used to estimate the binding affinity of single S366-374 mutants to H-2 Kd. Y367 and L374 were predicated to possess the most important role in peptide binding. Additionally, these one residue mutated peptides were synthesized, and IFN-gamma production induced by G368, V369, A371, T372 and K373 mutated S366-374 were decreased obviously.
We demonstrated that S366-374 is an optimal H-2 Kd CTL epitope in the SARS CoV S protein. Moreover, Y367, S370, and L374 are anchors in the epitope, while C366, G368, V369, A371, T372, and K373 may directly interact with TCR on the surface of CD8-T cells.
The online version of this article (doi:10.1186/1471-2172-13-50) contains supplementary material, which is available to authorized users.
Url:
DOI: 10.1186/1471-2172-13-50
PubMed: 22963340
PubMed Central: 3575293
Affiliations:
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<term>Cells, Cultured</term>
<term>Computational Biology</term>
<term>Enzyme-Linked Immunospot Assay</term>
<term>Epitope Mapping (methods)</term>
<term>Epitopes, T-Lymphocyte (immunology)</term>
<term>Epitopes, T-Lymphocyte (metabolism)</term>
<term>Female</term>
<term>Interferon-gamma (metabolism)</term>
<term>Membrane Glycoproteins (immunology)</term>
<term>Membrane Glycoproteins (metabolism)</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Peptide Fragments (immunology)</term>
<term>Peptide Fragments (metabolism)</term>
<term>Protein Binding</term>
<term>SARS Virus (immunology)</term>
<term>Sequence Analysis, Protein</term>
<term>Severe Acute Respiratory Syndrome (immunology)</term>
<term>Spike Glycoprotein, Coronavirus</term>
<term>T-Lymphocytes, Cytotoxic (immunology)</term>
<term>Viral Envelope Proteins (immunology)</term>
<term>Viral Envelope Proteins (metabolism)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Analyse de séquence de protéine</term>
<term>Animaux</term>
<term>Biologie informatique</term>
<term>Cartographie épitopique ()</term>
<term>Cellules cultivées</term>
<term>Déterminants antigéniques des lymphocytes T (immunologie)</term>
<term>Déterminants antigéniques des lymphocytes T (métabolisme)</term>
<term>Femelle</term>
<term>Fragments peptidiques (immunologie)</term>
<term>Fragments peptidiques (métabolisme)</term>
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<term>Peptide Fragments</term>
<term>Viral Envelope Proteins</term>
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<term>Interferon-gamma</term>
<term>Membrane Glycoproteins</term>
<term>Peptide Fragments</term>
<term>Viral Envelope Proteins</term>
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<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Déterminants antigéniques des lymphocytes T</term>
<term>Fragments peptidiques</term>
<term>Glycoprotéines membranaires</term>
<term>Lymphocytes T cytotoxiques</term>
<term>Protéines de l'enveloppe virale</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Virus du SRAS</term>
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<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>SARS Virus</term>
<term>Severe Acute Respiratory Syndrome</term>
<term>T-Lymphocytes, Cytotoxic</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Epitope Mapping</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Déterminants antigéniques des lymphocytes T</term>
<term>Fragments peptidiques</term>
<term>Glycoprotéines membranaires</term>
<term>Interféron gamma</term>
<term>Protéines de l'enveloppe virale</term>
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<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Cells, Cultured</term>
<term>Computational Biology</term>
<term>Enzyme-Linked Immunospot Assay</term>
<term>Female</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Protein Binding</term>
<term>Sequence Analysis, Protein</term>
<term>Spike Glycoprotein, Coronavirus</term>
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<term>Animaux</term>
<term>Biologie informatique</term>
<term>Cartographie épitopique</term>
<term>Cellules cultivées</term>
<term>Femelle</term>
<term>Glycoprotéine de spicule des coronavirus</term>
<term>Liaison aux protéines</term>
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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Severe acute respiratory syndrome (SARS) is an emerging infectious disease caused by the novel coronavirus SARS-CoV. The T cell epitopes of the SARS CoV spike protein are well known, but no systematic evaluation of the functional and structural roles of each residue has been reported for these antigenic epitopes. Analysis of the functional importance of side-chains by mutational study may exaggerate the effect by imposing a structural disturbance or an unusual steric, electrostatic or hydrophobic interaction.</p>
</sec>
<sec><title>Results</title>
<p>We demonstrated that N50 could induce significant IFN-gamma response from SARS-CoV S DNA immunized mice splenocytes by the means of ELISA, ELISPOT and FACS. Moreover, S366-374 was predicted to be an optimal epitope by bioinformatics tools: ANN, SMM, ARB and BIMAS, and confirmed by IFN-gamma response induced by a series of S358-374-derived peptides. Furthermore, each of S366-374 was replaced by alanine (A), lysine (K) or aspartic acid (D), respectively. ANN was used to estimate the binding affinity of single S366-374 mutants to H-2 Kd. Y367 and L374 were predicated to possess the most important role in peptide binding. Additionally, these one residue mutated peptides were synthesized, and IFN-gamma production induced by G368, V369, A371, T372 and K373 mutated S366-374 were decreased obviously.</p>
</sec>
<sec><title>Conclusions</title>
<p>We demonstrated that S366-374 is an optimal H-2 Kd CTL epitope in the SARS CoV S protein. Moreover, Y367, S370, and L374 are anchors in the epitope, while C366, G368, V369, A371, T372, and K373 may directly interact with TCR on the surface of CD8-T cells.</p>
</sec>
<sec><title>Electronic supplementary material</title>
<p>The online version of this article (doi:10.1186/1471-2172-13-50) contains supplementary material, which is available to authorized users.</p>
</sec>
</div>
</front>
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<author><name sortKey="Preiser, W" uniqKey="Preiser W">W Preiser</name>
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<author><name sortKey="Van Der Werf, S" uniqKey="Van Der Werf S">S van der Werf</name>
</author>
<author><name sortKey="Brodt, Hr" uniqKey="Brodt H">HR Brodt</name>
</author>
<author><name sortKey="Becker, S" uniqKey="Becker S">S Becker</name>
</author>
<author><name sortKey="Rabenau, H" uniqKey="Rabenau H">H Rabenau</name>
</author>
<author><name sortKey="Panning, M" uniqKey="Panning M">M Panning</name>
</author>
<author><name sortKey="Kolesnikova, L" uniqKey="Kolesnikova L">L Kolesnikova</name>
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</author>
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<author><name sortKey="Guan, Y" uniqKey="Guan Y">Y Guan</name>
</author>
<author><name sortKey="Yam, Ly" uniqKey="Yam L">LY Yam</name>
</author>
<author><name sortKey="Lim, W" uniqKey="Lim W">W Lim</name>
</author>
<author><name sortKey="Nicholls, J" uniqKey="Nicholls J">J Nicholls</name>
</author>
<author><name sortKey="Yee, Wk" uniqKey="Yee W">WK Yee</name>
</author>
<author><name sortKey="Yan, Ww" uniqKey="Yan W">WW Yan</name>
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</author>
<author><name sortKey="To, Kf" uniqKey="To K">KF To</name>
</author>
<author><name sortKey="Chan, Pk" uniqKey="Chan P">PK Chan</name>
</author>
<author><name sortKey="Lo, Aw" uniqKey="Lo A">AW Lo</name>
</author>
<author><name sortKey="Ng, Kc" uniqKey="Ng K">KC Ng</name>
</author>
<author><name sortKey="Wu, A" uniqKey="Wu A">A Wu</name>
</author>
<author><name sortKey="Lee, N" uniqKey="Lee N">N Lee</name>
</author>
<author><name sortKey="Wong, Hc" uniqKey="Wong H">HC Wong</name>
</author>
<author><name sortKey="Mak, Sm" uniqKey="Mak S">SM Mak</name>
</author>
<author><name sortKey="Chan, Kf" uniqKey="Chan K">KF Chan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rota, Pa" uniqKey="Rota P">PA Rota</name>
</author>
<author><name sortKey="Oberste, Ms" uniqKey="Oberste M">MS Oberste</name>
</author>
<author><name sortKey="Monroe, Ss" uniqKey="Monroe S">SS Monroe</name>
</author>
<author><name sortKey="Nix, Wa" uniqKey="Nix W">WA Nix</name>
</author>
<author><name sortKey="Campagnoli, R" uniqKey="Campagnoli R">R Campagnoli</name>
</author>
<author><name sortKey="Icenogle, Jp" uniqKey="Icenogle J">JP Icenogle</name>
</author>
<author><name sortKey="Penaranda, S" uniqKey="Penaranda S">S Penaranda</name>
</author>
<author><name sortKey="Bankamp, B" uniqKey="Bankamp B">B Bankamp</name>
</author>
<author><name sortKey="Maher, K" uniqKey="Maher K">K Maher</name>
</author>
<author><name sortKey="Chen, Mh" uniqKey="Chen M">MH Chen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Marra, Ma" uniqKey="Marra M">MA Marra</name>
</author>
<author><name sortKey="Jones, Sj" uniqKey="Jones S">SJ Jones</name>
</author>
<author><name sortKey="Astell, Cr" uniqKey="Astell C">CR Astell</name>
</author>
<author><name sortKey="Holt, Ra" uniqKey="Holt R">RA Holt</name>
</author>
<author><name sortKey="Brooks Wilson, A" uniqKey="Brooks Wilson A">A Brooks-Wilson</name>
</author>
<author><name sortKey="Butterfield, Ys" uniqKey="Butterfield Y">YS Butterfield</name>
</author>
<author><name sortKey="Khattra, J" uniqKey="Khattra J">J Khattra</name>
</author>
<author><name sortKey="Asano, Jk" uniqKey="Asano J">JK Asano</name>
</author>
<author><name sortKey="Barber, Sa" uniqKey="Barber S">SA Barber</name>
</author>
<author><name sortKey="Chan, Sy" uniqKey="Chan S">SY Chan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="He, Y" uniqKey="He Y">Y He</name>
</author>
<author><name sortKey="Zhou, Y" uniqKey="Zhou Y">Y Zhou</name>
</author>
<author><name sortKey="Siddiqui, P" uniqKey="Siddiqui P">P Siddiqui</name>
</author>
<author><name sortKey="Jiang, S" uniqKey="Jiang S">S Jiang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Huang, J" uniqKey="Huang J">J Huang</name>
</author>
<author><name sortKey="Cao, Y" uniqKey="Cao Y">Y Cao</name>
</author>
<author><name sortKey="Du, J" uniqKey="Du J">J Du</name>
</author>
<author><name sortKey="Bu, X" uniqKey="Bu X">X Bu</name>
</author>
<author><name sortKey="Ma, R" uniqKey="Ma R">R Ma</name>
</author>
<author><name sortKey="Wu, C" uniqKey="Wu C">C Wu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Laugel, B" uniqKey="Laugel B">B Laugel</name>
</author>
<author><name sortKey="Van Der Berg, Ha" uniqKey="Van Der Berg H">HA van der Berg</name>
</author>
<author><name sortKey="Gostick, E" uniqKey="Gostick E">E Gostick</name>
</author>
<author><name sortKey="Cole, Dk" uniqKey="Cole D">DK Cole</name>
</author>
<author><name sortKey="Wooldridge, L" uniqKey="Wooldridge L">L Wooldridge</name>
</author>
<author><name sortKey="Boulter, J" uniqKey="Boulter J">J Boulter</name>
</author>
<author><name sortKey="Milicic, A" uniqKey="Milicic A">A Milicic</name>
</author>
<author><name sortKey="Price, Da" uniqKey="Price D">DA Price</name>
</author>
<author><name sortKey="Sewell, Ak" uniqKey="Sewell A">AK Sewell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Anderson, Mw" uniqKey="Anderson M">MW Anderson</name>
</author>
<author><name sortKey="Gorski, J" uniqKey="Gorski J">J Gorski</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lee, Y" uniqKey="Lee Y">Y Lee</name>
</author>
<author><name sortKey="Ferrari, G" uniqKey="Ferrari G">G Ferrari</name>
</author>
<author><name sortKey="Lee, Sc" uniqKey="Lee S">SC Lee</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yang, Zy" uniqKey="Yang Z">ZY Yang</name>
</author>
<author><name sortKey="Kong, Wp" uniqKey="Kong W">WP Kong</name>
</author>
<author><name sortKey="Huang, Y" uniqKey="Huang Y">Y Huang</name>
</author>
<author><name sortKey="Roberts, A" uniqKey="Roberts A">A Roberts</name>
</author>
<author><name sortKey="Murphy, Br" uniqKey="Murphy B">BR Murphy</name>
</author>
<author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K Subbarao</name>
</author>
<author><name sortKey="Nabel, Gj" uniqKey="Nabel G">GJ Nabel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Thompson, Re" uniqKey="Thompson R">RE Thompson</name>
</author>
<author><name sortKey="Jolliffe, Ka" uniqKey="Jolliffe K">KA Jolliffe</name>
</author>
<author><name sortKey="Payne, Rj" uniqKey="Payne R">RJ Payne</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Meister, Ge" uniqKey="Meister G">GE Meister</name>
</author>
<author><name sortKey="Roberts, Cg" uniqKey="Roberts C">CG Roberts</name>
</author>
<author><name sortKey="Berzofsky, Ja" uniqKey="Berzofsky J">JA Berzofsky</name>
</author>
<author><name sortKey="De Groot, As" uniqKey="De Groot A">AS De Groot</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Buus, S" uniqKey="Buus S">S Buus</name>
</author>
<author><name sortKey="Lauemoller, Sl" uniqKey="Lauemoller S">SL Lauemoller</name>
</author>
<author><name sortKey="Worning, P" uniqKey="Worning P">P Worning</name>
</author>
<author><name sortKey="Kesmir, C" uniqKey="Kesmir C">C Kesmir</name>
</author>
<author><name sortKey="Frimurer, T" uniqKey="Frimurer T">T Frimurer</name>
</author>
<author><name sortKey="Corbet, S" uniqKey="Corbet S">S Corbet</name>
</author>
<author><name sortKey="Fomsgaard, A" uniqKey="Fomsgaard A">A Fomsgaard</name>
</author>
<author><name sortKey="Hilden, J" uniqKey="Hilden J">J Hilden</name>
</author>
<author><name sortKey="Holm, A" uniqKey="Holm A">A Holm</name>
</author>
<author><name sortKey="Brunak, S" uniqKey="Brunak S">S Brunak</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brusic, V" uniqKey="Brusic V">V Brusic</name>
</author>
<author><name sortKey="Bajic, Vb" uniqKey="Bajic V">VB Bajic</name>
</author>
<author><name sortKey="Petrovsky, N" uniqKey="Petrovsky N">N Petrovsky</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Peters, B" uniqKey="Peters B">B Peters</name>
</author>
<author><name sortKey="Sette, A" uniqKey="Sette A">A Sette</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Peters, B" uniqKey="Peters B">B Peters</name>
</author>
<author><name sortKey="Tong, W" uniqKey="Tong W">W Tong</name>
</author>
<author><name sortKey="Sidney, J" uniqKey="Sidney J">J Sidney</name>
</author>
<author><name sortKey="Sette, A" uniqKey="Sette A">A Sette</name>
</author>
<author><name sortKey="Weng, Z" uniqKey="Weng Z">Z Weng</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Doytchinova, Ia" uniqKey="Doytchinova I">IA Doytchinova</name>
</author>
<author><name sortKey="Guan, P" uniqKey="Guan P">P Guan</name>
</author>
<author><name sortKey="Flower, Dr" uniqKey="Flower D">DR Flower</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bui, Hh" uniqKey="Bui H">HH Bui</name>
</author>
<author><name sortKey="Sidney, J" uniqKey="Sidney J">J Sidney</name>
</author>
<author><name sortKey="Peters, B" uniqKey="Peters B">B Peters</name>
</author>
<author><name sortKey="Sathiamurthy, M" uniqKey="Sathiamurthy M">M Sathiamurthy</name>
</author>
<author><name sortKey="Sinichi, A" uniqKey="Sinichi A">A Sinichi</name>
</author>
<author><name sortKey="Purton, Ka" uniqKey="Purton K">KA Purton</name>
</author>
<author><name sortKey="Mothe, Br" uniqKey="Mothe B">BR Mothe</name>
</author>
<author><name sortKey="Chisari, Fv" uniqKey="Chisari F">FV Chisari</name>
</author>
<author><name sortKey="Watkins, Di" uniqKey="Watkins D">DI Watkins</name>
</author>
<author><name sortKey="Sette, A" uniqKey="Sette A">A Sette</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Peters, B" uniqKey="Peters B">B Peters</name>
</author>
<author><name sortKey="Bui, Hh" uniqKey="Bui H">HH Bui</name>
</author>
<author><name sortKey="Frankild, S" uniqKey="Frankild S">S Frankild</name>
</author>
<author><name sortKey="Nielson, M" uniqKey="Nielson M">M Nielson</name>
</author>
<author><name sortKey="Lundegaard, C" uniqKey="Lundegaard C">C Lundegaard</name>
</author>
<author><name sortKey="Kostem, E" uniqKey="Kostem E">E Kostem</name>
</author>
<author><name sortKey="Basch, D" uniqKey="Basch D">D Basch</name>
</author>
<author><name sortKey="Lamberth, K" uniqKey="Lamberth K">K Lamberth</name>
</author>
<author><name sortKey="Harndahl, M" uniqKey="Harndahl M">M Harndahl</name>
</author>
<author><name sortKey="Fleri, W" uniqKey="Fleri W">W Fleri</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, P" uniqKey="Wang P">P Wang</name>
</author>
<author><name sortKey="Sidney, J" uniqKey="Sidney J">J Sidney</name>
</author>
<author><name sortKey="Kim, Y" uniqKey="Kim Y">Y Kim</name>
</author>
<author><name sortKey="Sette, A" uniqKey="Sette A">A Sette</name>
</author>
<author><name sortKey="Lund, O" uniqKey="Lund O">O Lund</name>
</author>
<author><name sortKey="Nielsen, M" uniqKey="Nielsen M">M Nielsen</name>
</author>
<author><name sortKey="Peters, B" uniqKey="Peters B">B Peters</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Parker, Kc" uniqKey="Parker K">KC Parker</name>
</author>
<author><name sortKey="Bednarek, Ma" uniqKey="Bednarek M">MA Bednarek</name>
</author>
<author><name sortKey="Coligan, Je" uniqKey="Coligan J">JE Coligan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nielsen, M" uniqKey="Nielsen M">M Nielsen</name>
</author>
<author><name sortKey="Lund, O" uniqKey="Lund O">O Lund</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, B" uniqKey="Wang B">B Wang</name>
</author>
<author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name>
</author>
<author><name sortKey="Jiang, X" uniqKey="Jiang X">X Jiang</name>
</author>
<author><name sortKey="Zhang, M" uniqKey="Zhang M">M Zhang</name>
</author>
<author><name sortKey="Wan, T" uniqKey="Wan T">T Wan</name>
</author>
<author><name sortKey="Li, N" uniqKey="Li N">N Li</name>
</author>
<author><name sortKey="Zhou, X" uniqKey="Zhou X">X Zhou</name>
</author>
<author><name sortKey="Wu, Y" uniqKey="Wu Y">Y Wu</name>
</author>
<author><name sortKey="Yang, F" uniqKey="Yang F">F Yang</name>
</author>
<author><name sortKey="Yu, Y" uniqKey="Yu Y">Y Yu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yang, J" uniqKey="Yang J">J Yang</name>
</author>
<author><name sortKey="James, E" uniqKey="James E">E James</name>
</author>
<author><name sortKey="Roti, M" uniqKey="Roti M">M Roti</name>
</author>
<author><name sortKey="Huston, L" uniqKey="Huston L">L Huston</name>
</author>
<author><name sortKey="Gebe, Ja" uniqKey="Gebe J">JA Gebe</name>
</author>
<author><name sortKey="Kwok, Ww" uniqKey="Kwok W">WW Kwok</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhi, Y" uniqKey="Zhi Y">Y Zhi</name>
</author>
<author><name sortKey="Kobinger, Gp" uniqKey="Kobinger G">GP Kobinger</name>
</author>
<author><name sortKey="Jordan, H" uniqKey="Jordan H">H Jordan</name>
</author>
<author><name sortKey="Suchma, K" uniqKey="Suchma K">K Suchma</name>
</author>
<author><name sortKey="Weiss, Sr" uniqKey="Weiss S">SR Weiss</name>
</author>
<author><name sortKey="Shen, H" uniqKey="Shen H">H Shen</name>
</author>
<author><name sortKey="Schumer, G" uniqKey="Schumer G">G Schumer</name>
</author>
<author><name sortKey="Gao, G" uniqKey="Gao G">G Gao</name>
</author>
<author><name sortKey="Boyer, Jl" uniqKey="Boyer J">JL Boyer</name>
</author>
<author><name sortKey="Crystal, Rg" uniqKey="Crystal R">RG Crystal</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Boesteanu, A" uniqKey="Boesteanu A">A Boesteanu</name>
</author>
<author><name sortKey="Brehm, M" uniqKey="Brehm M">M Brehm</name>
</author>
<author><name sortKey="Mylin, Lm" uniqKey="Mylin L">LM Mylin</name>
</author>
<author><name sortKey="Christianson, Gj" uniqKey="Christianson G">GJ Christianson</name>
</author>
<author><name sortKey="Tevethia, Ss" uniqKey="Tevethia S">SS Tevethia</name>
</author>
<author><name sortKey="Roopenian, Dc" uniqKey="Roopenian D">DC Roopenian</name>
</author>
<author><name sortKey="Joyce, S" uniqKey="Joyce S">S Joyce</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Robinson, Ra" uniqKey="Robinson R">RA Robinson</name>
</author>
<author><name sortKey="Lee, Dr" uniqKey="Lee D">DR Lee</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Malik, A" uniqKey="Malik A">A Malik</name>
</author>
<author><name sortKey="Houghten, R" uniqKey="Houghten R">R Houghten</name>
</author>
<author><name sortKey="Corradin, G" uniqKey="Corradin G">G Corradin</name>
</author>
<author><name sortKey="Buus, S" uniqKey="Buus S">S Buus</name>
</author>
<author><name sortKey="Berzofsky, Ja" uniqKey="Berzofsky J">JA Berzofsky</name>
</author>
<author><name sortKey="Hoffman, Sl" uniqKey="Hoffman S">SL Hoffman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mitaksov, V" uniqKey="Mitaksov V">V Mitaksov</name>
</author>
<author><name sortKey="Fremont, Dh" uniqKey="Fremont D">DH Fremont</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wells, Ja" uniqKey="Wells J">JA Wells</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Arabshahi, A" uniqKey="Arabshahi A">A Arabshahi</name>
</author>
<author><name sortKey="Frey, Pa" uniqKey="Frey P">PA Frey</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Srinivasan, Kn" uniqKey="Srinivasan K">KN Srinivasan</name>
</author>
<author><name sortKey="Zhang, Gl" uniqKey="Zhang G">GL Zhang</name>
</author>
<author><name sortKey="Khan, Am" uniqKey="Khan A">AM Khan</name>
</author>
<author><name sortKey="August, Jt" uniqKey="August J">JT August</name>
</author>
<author><name sortKey="Brusic, V" uniqKey="Brusic V">V Brusic</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Soam, Ss" uniqKey="Soam S">SS Soam</name>
</author>
<author><name sortKey="Khan, F" uniqKey="Khan F">F Khan</name>
</author>
<author><name sortKey="Bhasker, B" uniqKey="Bhasker B">B Bhasker</name>
</author>
<author><name sortKey="Mishra, Bn" uniqKey="Mishra B">BN Mishra</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lin, Hh" uniqKey="Lin H">HH Lin</name>
</author>
<author><name sortKey="Ray, S" uniqKey="Ray S">S Ray</name>
</author>
<author><name sortKey="Tongchusak, S" uniqKey="Tongchusak S">S Tongchusak</name>
</author>
<author><name sortKey="Reinherz, El" uniqKey="Reinherz E">EL Reinherz</name>
</author>
<author><name sortKey="Brusic, V" uniqKey="Brusic V">V Brusic</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhang, Gl" uniqKey="Zhang G">GL Zhang</name>
</author>
<author><name sortKey="Srinivasan, Kn" uniqKey="Srinivasan K">KN Srinivasan</name>
</author>
<author><name sortKey="Veeramani, A" uniqKey="Veeramani A">A Veeramani</name>
</author>
<author><name sortKey="August, Jt" uniqKey="August J">JT August</name>
</author>
<author><name sortKey="Brusic, V" uniqKey="Brusic V">V Brusic</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bolin, Dr" uniqKey="Bolin D">DR Bolin</name>
</author>
<author><name sortKey="Swain, Al" uniqKey="Swain A">AL Swain</name>
</author>
<author><name sortKey="Sarabu, R" uniqKey="Sarabu R">R Sarabu</name>
</author>
<author><name sortKey="Berthel, Sj" uniqKey="Berthel S">SJ Berthel</name>
</author>
<author><name sortKey="Gillespie, P" uniqKey="Gillespie P">P Gillespie</name>
</author>
<author><name sortKey="Huby, Nj" uniqKey="Huby N">NJ Huby</name>
</author>
<author><name sortKey="Makofske, R" uniqKey="Makofske R">R Makofske</name>
</author>
<author><name sortKey="Orzechowski, L" uniqKey="Orzechowski L">L Orzechowski</name>
</author>
<author><name sortKey="Perrotta, A" uniqKey="Perrotta A">A Perrotta</name>
</author>
<author><name sortKey="Toth, K" uniqKey="Toth K">K Toth</name>
</author>
</analytic>
</biblStruct>
</listBibl>
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<tree><country name="République populaire de Chine"><noRegion><name sortKey="Huang, Jun" sort="Huang, Jun" uniqKey="Huang J" first="Jun" last="Huang">Jun Huang</name>
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