Posttraumatic stress disorder in convalescent severe acute respiratory syndrome patients: a 4-year follow-up study☆
Identifieur interne : 002A54 ( Main/Exploration ); précédent : 002A53; suivant : 002A55Posttraumatic stress disorder in convalescent severe acute respiratory syndrome patients: a 4-year follow-up study☆
Auteurs : Xia Hong [République populaire de Chine, États-Unis] ; Glenn W. Currier [États-Unis] ; Xiaohui Zhao [République populaire de Chine] ; Yinan Jiang [République populaire de Chine] ; Wei Zhou [République populaire de Chine] ; Jing Wei [République populaire de Chine]Source :
- General Hospital Psychiatry [ 0163-8343 ] ; 2009.
Abstract
To measure the incidence and impact of posttraumatic stress disorder (PTSD) in a cohort of 70 subjects with severe acute respiratory syndrome (SARS).
Clinical assessments of PTSD were conducted at 2, 7, 10, 20 and 46 months after discharge from medical hospitalization for treatment of SARS. Diagnoses of PTSD were established by a trained psychiatrist using the
Of the 68 subjects who finished at least two follow-up interviews, 30 developed PTSD over the study period (44.1%). Scores on IES, SAS, SDS and SCL-90 (
PTSD occurs in a significant percentage of subjects who recover from SARS, and the occurrence of PTSD predicts persistent psychological distress and diminished social functioning in the 4 years after SARS treatment.
Url:
DOI: 10.1016/j.genhosppsych.2009.06.008
PubMed: 19892213
PubMed Central: 7112559
Affiliations:
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Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhou, Wei" sort="Zhou, Wei" uniqKey="Zhou W" first="Wei" last="Zhou">Wei Zhou</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Psychological Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Psychological Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wei, Jing" sort="Wei, Jing" uniqKey="Wei J" first="Jing" last="Wei">Jing 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rid="d32e2490">☆</xref></sup></title><author><name sortKey="Hong, Xia" sort="Hong, Xia" uniqKey="Hong X" first="Xia" last="Hong">Xia Hong</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Psychological Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Psychological Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff2">Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Currier, Glenn W" sort="Currier, Glenn W" uniqKey="Currier G" first="Glenn W." last="Currier">Glenn W. Currier</name><affiliation wicri:level="2"><nlm:aff id="aff2">Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff3">Department of Emergency Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Emergency Medicine, University of Rochester Medical Center, Rochester, NY 14642</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Zhao, Xiaohui" sort="Zhao, Xiaohui" uniqKey="Zhao X" first="Xiaohui" last="Zhao">Xiaohui Zhao</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Psychological Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Psychological Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Jiang, Yinan" sort="Jiang, Yinan" uniqKey="Jiang Y" first="Yinan" last="Jiang">Yinan Jiang</name><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Internal Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Internal Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhou, Wei" sort="Zhou, Wei" uniqKey="Zhou W" first="Wei" last="Zhou">Wei Zhou</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Psychological Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Psychological Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wei, Jing" sort="Wei, Jing" uniqKey="Wei J" first="Jing" last="Wei">Jing Wei</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Psychological Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Psychological Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></analytic><series><title level="j">General Hospital Psychiatry</title><idno type="ISSN">0163-8343</idno><idno type="eISSN">1873-7714</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objective</title><p>To measure the incidence and impact of posttraumatic stress disorder (PTSD) in a cohort of 70 subjects with severe acute respiratory syndrome (SARS).</p></sec><sec><title>Methods</title><p>Clinical assessments of PTSD were conducted at 2, 7, 10, 20 and 46 months after discharge from medical hospitalization for treatment of SARS. Diagnoses of PTSD were established by a trained psychiatrist using the <italic>Chinese Classification of Mental Disorders</italic> (<italic>CCMD-III</italic>) and <italic>Diagnostic and Statistical Manual of Mental Disorders, 4th Edition</italic> (<italic>DSM-IV</italic>) criteria. To study the impact of PTSD, we used the Impact of Event Scale (IES), Zung Self-Rating Anxiety Scale (SAS), Zung Self-Rating Depression Scale (SDS), Symptom Checklist 90 (SCL-90), Short Form-36 (SF-36 Health Survey) and Social Disability Screening Schedule (SDSS).</p></sec><sec><title>Results</title><p>Of the 68 subjects who finished at least two follow-up interviews, 30 developed PTSD over the study period (44.1%). Scores on IES, SAS, SDS and SCL-90 (<italic>P</italic><.0001) were higher, and functional impairment as measured by SF-36 (<italic>P</italic><.0001) and SDSS was more severe (<italic>P</italic>=.0073) for subjects with PTSD.</p></sec><sec><title>Conclusion</title><p>PTSD occurs in a significant percentage of subjects who recover from SARS, and the occurrence of PTSD predicts persistent psychological distress and diminished social functioning in the 4 years after SARS treatment.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="World Health Organization" uniqKey="World Health Organization">World Health Organization</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="World Health Organization" uniqKey="World Health Organization">World Health Organization</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liang, W" uniqKey="Liang W">W. 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Hokema</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li><li>États-Unis</li></country><region><li>État de New York</li></region><settlement><li>Pékin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Hong, Xia" sort="Hong, Xia" uniqKey="Hong X" first="Xia" last="Hong">Xia Hong</name></noRegion><name sortKey="Jiang, Yinan" sort="Jiang, Yinan" uniqKey="Jiang Y" first="Yinan" last="Jiang">Yinan Jiang</name><name sortKey="Wei, Jing" sort="Wei, Jing" uniqKey="Wei J" first="Jing" last="Wei">Jing Wei</name><name sortKey="Zhao, Xiaohui" sort="Zhao, Xiaohui" uniqKey="Zhao X" first="Xiaohui" last="Zhao">Xiaohui Zhao</name><name sortKey="Zhou, Wei" sort="Zhou, Wei" uniqKey="Zhou W" first="Wei" last="Zhou">Wei Zhou</name></country><country name="États-Unis"><region name="État de New York"><name sortKey="Hong, Xia" sort="Hong, Xia" uniqKey="Hong X" first="Xia" last="Hong">Xia Hong</name></region><name sortKey="Currier, Glenn W" sort="Currier, Glenn W" uniqKey="Currier G" first="Glenn W." last="Currier">Glenn W. 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