Seroprevalence of SARS coronavirus antibody in household contacts
Identifieur interne : 004963 ( Main/Exploration ); précédent : 004962; suivant : 004964Seroprevalence of SARS coronavirus antibody in household contacts
Auteurs : C.-C. Lee [Taïwan] ; S.-Y. Chen [Taïwan] ; I.-J. Chang [Taïwan] ; P.-C. Tsai [Taïwan] ; T.-C. Lu [Taïwan] ; P.-L. Wu [Taïwan] ; W.-J. Chen [Taïwan] ; L.-M. Huang [Taïwan] ; S.-C. Chang [Taïwan]Source :
- Epidemiology and Infection [ 0950-2688 ] ; 2005-12.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Anticorps antiviraux (sang), Femelle, Humains, Immunoglobuline G (sang), Mâle, Syndrome respiratoire aigu sévère (transmission), Syndrome respiratoire aigu sévère (épidémiologie), Traçage des contacts, Virus du SRAS (immunologie), Virus du SRAS (isolement et purification), Études séroépidémiologiques.
- MESH :
- immunologie : Virus du SRAS.
- isolement et purification : Virus du SRAS.
- sang : Anticorps antiviraux, Immunoglobuline G.
- épidémiologie : Syndrome respiratoire aigu sévère.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Mâle, Traçage des contacts, Études séroépidémiologiques.
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Adult, Antibodies, Viral (blood), Antibody, Contact Tracing, Epidemiology, Female, Human, Humans, Immunoglobulin G (blood), Male, Microbiology, Middle Aged, Prevalence, SARS Virus (immunology), SARS Virus (isolation & purification), Seroepidemiologic Studies, Serology, Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (transmission), Severe acute respiratory syndrome virus.
- MESH :
- chemical , blood : Antibodies, Viral, Immunoglobulin G.
- epidemiology : Severe Acute Respiratory Syndrome.
- immunology : SARS Virus.
- isolation & purification : SARS Virus.
- transmission : Severe Acute Respiratory Syndrome.
- Adult, Contact Tracing, Female, Humans, Male, Middle Aged, Seroepidemiologic Studies.
Abstract
Between March and July 2003, 671 cases of severe acute respiratory syndrome (SARS) were diagnosed in Taiwan with a total of 84 fatalities. After the epidemic, a serological survey was conducted involving the asymptomatic household contacts. Household contacts of 13 index patients were enrolled in the study. Contact history and clinical symptoms of the household contacts were recorded by standardized questionnaires. Blood samples of patients and household contacts were collected at least 28 days after symptom onset in the index patients or household exposure in the contacts for SARS-associated coronavirus (SARS-CoV) IgG testing. On the basis of this investigation, 29 persons (25 adults and 4 children) were identified as having had unprotected exposure to the index cases before infection-control practices were implemented. Laboratory evaluation of clinical specimens showed no evidence of transmission of SARS-CoV infection to any contacts. This investigation demonstrated that subclinical transmission among household contacts was low in the described setting.
Url:
- https://api.istex.fr/ark:/67375/6GQ-HD0GF94C-V/fulltext.pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870347
DOI: 10.1017/S0950268805004541
Affiliations:
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Le document en format XML
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Lee</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Emergency Medicine, National Taiwan University Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Chen, S Y" sort="Chen, S Y" uniqKey="Chen S" first="S.-Y." last="Chen">S.-Y. Chen</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Emergency Medicine, National Taiwan University Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Chang, I J" sort="Chang, I J" uniqKey="Chang I" first="I.-J." last="Chang">I.-J. Chang</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Institute of Preventive Medicine, School of Public Health, National Taiwan University, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Tsai, P C" sort="Tsai, P C" uniqKey="Tsai P" first="P.-C." last="Tsai">P.-C. Tsai</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Emergency Medicine, National Taiwan University Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Lu, T C" sort="Lu, T C" uniqKey="Lu T" first="T.-C." last="Lu">T.-C. 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After the epidemic, a serological survey was conducted involving the asymptomatic household contacts. Household contacts of 13 index patients were enrolled in the study. Contact history and clinical symptoms of the household contacts were recorded by standardized questionnaires. Blood samples of patients and household contacts were collected at least 28 days after symptom onset in the index patients or household exposure in the contacts for SARS-associated coronavirus (SARS-CoV) IgG testing. On the basis of this investigation, 29 persons (25 adults and 4 children) were identified as having had unprotected exposure to the index cases before infection-control practices were implemented. Laboratory evaluation of clinical specimens showed no evidence of transmission of SARS-CoV infection to any contacts. This investigation demonstrated that subclinical transmission among household contacts was low in the described setting.</div></front></TEI><affiliations><list><country><li>Taïwan</li></country></list><tree><country name="Taïwan"><noRegion><name sortKey="Lee, C C" sort="Lee, C C" uniqKey="Lee C" first="C.-C." last="Lee">C.-C. Lee</name></noRegion><name sortKey="Chang, I J" sort="Chang, I J" uniqKey="Chang I" first="I.-J." last="Chang">I.-J. Chang</name><name sortKey="Chang, S C" sort="Chang, S C" uniqKey="Chang S" first="S.-C." last="Chang">S.-C. Chang</name><name sortKey="Chen, S Y" sort="Chen, S Y" uniqKey="Chen S" first="S.-Y." last="Chen">S.-Y. Chen</name><name sortKey="Chen, W J" sort="Chen, W J" uniqKey="Chen W" first="W.-J." last="Chen">W.-J. Chen</name><name sortKey="Huang, L M" sort="Huang, L M" uniqKey="Huang L" first="L.-M." last="Huang">L.-M. Huang</name><name sortKey="Lu, T C" sort="Lu, T C" uniqKey="Lu T" first="T.-C." last="Lu">T.-C. Lu</name><name sortKey="Tsai, P C" sort="Tsai, P C" uniqKey="Tsai P" first="P.-C." last="Tsai">P.-C. Tsai</name><name sortKey="Wu, P L" sort="Wu, P L" uniqKey="Wu P" first="P.-L." last="Wu">P.-L. Wu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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