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Seroprevalence of SARS coronavirus antibody in household contacts

Identifieur interne : 000560 ( PascalFrancis/Corpus ); précédent : 000559; suivant : 000561

Seroprevalence of SARS coronavirus antibody in household contacts

Auteurs : C.-C. Lee ; S.-Y. Chen ; I.-J. Chang ; P.-C. Tsai ; T.-C. Lu ; P.-L. Wu ; W.-J. Chen ; L.-M. Huang ; S.-C. Chang

Source :

RBID : Pascal:06-0050385

Descripteurs français

English descriptors

Abstract

Between March and July 2003, 671 cases of severe acute respiratory syndrome (SARS) were diagnosed in Taiwan with a total of 84 fatalities. After the epidemic, a serological survey was conducted involving the asymptomatic household contacts. Household contacts of 13 index patients were enrolled in the study. Contact history and clinical symptoms of the household contacts were recorded by standardized questionnaires. Blood samples of patients and household contacts were collected at least 28 days after symptom onset in the index patients or household exposure in the contacts for SARS-associated coronavirus (SARS-CoV) IgG testing. On the basis of this investigation, 29 persons (25 adults and 4 children) were identified as having had unprotected exposure to the index cases before infection-control practices were implemented. Laboratory evaluation of clinical specimens showed no evidence of transmission of SARS-CoV infection to any contacts. This investigation demonstrated that subclinical transmission among household contacts was low in the described setting.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
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A02 01      @0 EPINEU
A03   1    @0 Epidemiol. infect.
A05       @2 133
A06       @2 6
A08 01  1  ENG  @1 Seroprevalence of SARS coronavirus antibody in household contacts
A11 01  1    @1 LEE (C.-C.)
A11 02  1    @1 CHEN (S.-Y.)
A11 03  1    @1 CHANG (I.-J.)
A11 04  1    @1 TSAI (P.-C.)
A11 05  1    @1 LU (T.-C.)
A11 06  1    @1 WU (P.-L.)
A11 07  1    @1 CHEN (W.-J.)
A11 08  1    @1 HUANG (L.-M.)
A11 09  1    @1 CHANG (S.-C.)
A14 01      @1 Department of Emergency Medicine, National Taiwan University Hospital @2 Taipei @3 TWN @Z 1 aut. @Z 2 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut. @Z 7 aut.
A14 02      @1 Institute of Preventive Medicine, School of Public Health, National Taiwan University @2 Taipei @3 TWN @Z 3 aut.
A14 03      @1 Division of Infectious Disease, Department of Pediatrics, National Taiwan University Hospital @2 Taipei @3 TWN @Z 8 aut.
A14 04      @1 Division of Infectious Disease, Department of Internal Medicine, National Taiwan University Hospital @2 Taipei @3 TWN @Z 9 aut.
A20       @1 1119-1122
A21       @1 2005
A23 01      @0 ENG
A43 01      @1 INIST @2 6056 @5 354000135393910180
A44       @0 0000 @1 © 2006 INIST-CNRS. All rights reserved.
A45       @0 19 ref.
A47 01  1    @0 06-0050385
A60       @1 P
A61       @0 A
A64 01  1    @0 Epidemiology and infection
A66 01      @0 GBR
C01 01    ENG  @0 Between March and July 2003, 671 cases of severe acute respiratory syndrome (SARS) were diagnosed in Taiwan with a total of 84 fatalities. After the epidemic, a serological survey was conducted involving the asymptomatic household contacts. Household contacts of 13 index patients were enrolled in the study. Contact history and clinical symptoms of the household contacts were recorded by standardized questionnaires. Blood samples of patients and household contacts were collected at least 28 days after symptom onset in the index patients or household exposure in the contacts for SARS-associated coronavirus (SARS-CoV) IgG testing. On the basis of this investigation, 29 persons (25 adults and 4 children) were identified as having had unprotected exposure to the index cases before infection-control practices were implemented. Laboratory evaluation of clinical specimens showed no evidence of transmission of SARS-CoV infection to any contacts. This investigation demonstrated that subclinical transmission among household contacts was low in the described setting.
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C03 01  X  ENG  @0 Severe acute respiratory syndrome virus @2 NW @5 01
C03 01  X  SPA  @0 Severe acute respiratory syndrome virus @2 NW @5 01
C03 02  X  FRE  @0 Prévalence @5 05
C03 02  X  ENG  @0 Prevalence @5 05
C03 02  X  SPA  @0 Prevalencia @5 05
C03 03  X  FRE  @0 Sérologie @5 06
C03 03  X  ENG  @0 Serology @5 06
C03 03  X  SPA  @0 Serología @5 06
C03 04  X  FRE  @0 Anticorps @5 07
C03 04  X  ENG  @0 Antibody @5 07
C03 04  X  SPA  @0 Anticuerpo @5 07
C03 05  X  FRE  @0 Microbiologie @5 08
C03 05  X  ENG  @0 Microbiology @5 08
C03 05  X  SPA  @0 Microbiología @5 08
C03 06  X  FRE  @0 Epidémiologie @5 09
C03 06  X  ENG  @0 Epidemiology @5 09
C03 06  X  SPA  @0 Epidemiología @5 09
C03 07  X  FRE  @0 Homme @5 10
C03 07  X  ENG  @0 Human @5 10
C03 07  X  SPA  @0 Hombre @5 10
C07 01  X  FRE  @0 Coronavirus @2 NW
C07 01  X  ENG  @0 Coronavirus @2 NW
C07 01  X  SPA  @0 Coronavirus @2 NW
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C07 02  X  ENG  @0 Coronaviridae @2 NW
C07 02  X  SPA  @0 Coronaviridae @2 NW
C07 03  X  FRE  @0 Nidovirales @2 NW
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C07 03  X  SPA  @0 Nidovirales @2 NW
C07 04  X  FRE  @0 Virus @2 NW
C07 04  X  ENG  @0 Virus @2 NW
C07 04  X  SPA  @0 Virus @2 NW
N21       @1 023
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 06-0050385 INIST
ET : Seroprevalence of SARS coronavirus antibody in household contacts
AU : LEE (C.-C.); CHEN (S.-Y.); CHANG (I.-J.); TSAI (P.-C.); LU (T.-C.); WU (P.-L.); CHEN (W.-J.); HUANG (L.-M.); CHANG (S.-C.)
AF : Department of Emergency Medicine, National Taiwan University Hospital/Taipei/Taïwan (1 aut., 2 aut., 4 aut., 5 aut., 6 aut., 7 aut.); Institute of Preventive Medicine, School of Public Health, National Taiwan University/Taipei/Taïwan (3 aut.); Division of Infectious Disease, Department of Pediatrics, National Taiwan University Hospital/Taipei/Taïwan (8 aut.); Division of Infectious Disease, Department of Internal Medicine, National Taiwan University Hospital/Taipei/Taïwan (9 aut.)
DT : Publication en série; Niveau analytique
SO : Epidemiology and infection; ISSN 0950-2688; Coden EPINEU; Royaume-Uni; Da. 2005; Vol. 133; No. 6; Pp. 1119-1122; Bibl. 19 ref.
LA : Anglais
EA : Between March and July 2003, 671 cases of severe acute respiratory syndrome (SARS) were diagnosed in Taiwan with a total of 84 fatalities. After the epidemic, a serological survey was conducted involving the asymptomatic household contacts. Household contacts of 13 index patients were enrolled in the study. Contact history and clinical symptoms of the household contacts were recorded by standardized questionnaires. Blood samples of patients and household contacts were collected at least 28 days after symptom onset in the index patients or household exposure in the contacts for SARS-associated coronavirus (SARS-CoV) IgG testing. On the basis of this investigation, 29 persons (25 adults and 4 children) were identified as having had unprotected exposure to the index cases before infection-control practices were implemented. Laboratory evaluation of clinical specimens showed no evidence of transmission of SARS-CoV infection to any contacts. This investigation demonstrated that subclinical transmission among household contacts was low in the described setting.
CC : 002A05
FD : Virus syndrome respiratoire aigu sévère; Prévalence; Sérologie; Anticorps; Microbiologie; Epidémiologie; Homme
FG : Coronavirus; Coronaviridae; Nidovirales; Virus
ED : Severe acute respiratory syndrome virus; Prevalence; Serology; Antibody; Microbiology; Epidemiology; Human
EG : Coronavirus; Coronaviridae; Nidovirales; Virus
SD : Severe acute respiratory syndrome virus; Prevalencia; Serología; Anticuerpo; Microbiología; Epidemiología; Hombre
LO : INIST-6056.354000135393910180
ID : 06-0050385

Links to Exploration step

Pascal:06-0050385

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<div type="abstract" xml:lang="en">Between March and July 2003, 671 cases of severe acute respiratory syndrome (SARS) were diagnosed in Taiwan with a total of 84 fatalities. After the epidemic, a serological survey was conducted involving the asymptomatic household contacts. Household contacts of 13 index patients were enrolled in the study. Contact history and clinical symptoms of the household contacts were recorded by standardized questionnaires. Blood samples of patients and household contacts were collected at least 28 days after symptom onset in the index patients or household exposure in the contacts for SARS-associated coronavirus (SARS-CoV) IgG testing. On the basis of this investigation, 29 persons (25 adults and 4 children) were identified as having had unprotected exposure to the index cases before infection-control practices were implemented. Laboratory evaluation of clinical specimens showed no evidence of transmission of SARS-CoV infection to any contacts. This investigation demonstrated that subclinical transmission among household contacts was low in the described setting.</div>
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<s5>05</s5>
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<s2>NW</s2>
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<s1>023</s1>
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<s1>OTO</s1>
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<NO>PASCAL 06-0050385 INIST</NO>
<ET>Seroprevalence of SARS coronavirus antibody in household contacts</ET>
<AU>LEE (C.-C.); CHEN (S.-Y.); CHANG (I.-J.); TSAI (P.-C.); LU (T.-C.); WU (P.-L.); CHEN (W.-J.); HUANG (L.-M.); CHANG (S.-C.)</AU>
<AF>Department of Emergency Medicine, National Taiwan University Hospital/Taipei/Taïwan (1 aut., 2 aut., 4 aut., 5 aut., 6 aut., 7 aut.); Institute of Preventive Medicine, School of Public Health, National Taiwan University/Taipei/Taïwan (3 aut.); Division of Infectious Disease, Department of Pediatrics, National Taiwan University Hospital/Taipei/Taïwan (8 aut.); Division of Infectious Disease, Department of Internal Medicine, National Taiwan University Hospital/Taipei/Taïwan (9 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Epidemiology and infection; ISSN 0950-2688; Coden EPINEU; Royaume-Uni; Da. 2005; Vol. 133; No. 6; Pp. 1119-1122; Bibl. 19 ref.</SO>
<LA>Anglais</LA>
<EA>Between March and July 2003, 671 cases of severe acute respiratory syndrome (SARS) were diagnosed in Taiwan with a total of 84 fatalities. After the epidemic, a serological survey was conducted involving the asymptomatic household contacts. Household contacts of 13 index patients were enrolled in the study. Contact history and clinical symptoms of the household contacts were recorded by standardized questionnaires. Blood samples of patients and household contacts were collected at least 28 days after symptom onset in the index patients or household exposure in the contacts for SARS-associated coronavirus (SARS-CoV) IgG testing. On the basis of this investigation, 29 persons (25 adults and 4 children) were identified as having had unprotected exposure to the index cases before infection-control practices were implemented. Laboratory evaluation of clinical specimens showed no evidence of transmission of SARS-CoV infection to any contacts. This investigation demonstrated that subclinical transmission among household contacts was low in the described setting.</EA>
<CC>002A05</CC>
<FD>Virus syndrome respiratoire aigu sévère; Prévalence; Sérologie; Anticorps; Microbiologie; Epidémiologie; Homme</FD>
<FG>Coronavirus; Coronaviridae; Nidovirales; Virus</FG>
<ED>Severe acute respiratory syndrome virus; Prevalence; Serology; Antibody; Microbiology; Epidemiology; Human</ED>
<EG>Coronavirus; Coronaviridae; Nidovirales; Virus</EG>
<SD>Severe acute respiratory syndrome virus; Prevalencia; Serología; Anticuerpo; Microbiología; Epidemiología; Hombre</SD>
<LO>INIST-6056.354000135393910180</LO>
<ID>06-0050385</ID>
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