SrasV1, Main, Exploration, bibRecord, 004046

SARS transmission in Vietnam outside of the health-care setting

Identifieur interne : 004046 ( Main/Exploration ); précédent : 004045; suivant : 004047

SARS transmission in Vietnam outside of the health-care setting

Auteurs : P. A. Tuan [Viêt Nam] ; P. Horby [Viêt Nam] ; P. N. Dinh [Viêt Nam] ; L. T. Q. Mai [Viêt Nam] ; M. Zambon [Royaume-Uni] ; J. Shah [États-Unis] ; V. Q. Huy [Viêt Nam] ; S. Bloom [États-Unis] ; R. Gopal [Royaume-Uni] ; J. Comer [États-Unis] ; A. Plant [Australie]

Source :

Epidemiology and Infection [ 0950-2688 ] ; 2007-04.

RBID : ISTEX:842736DB46780B694FA9ACAB5580197ABA1A6172

Abstract

To evaluate the risk of transmission of SARS coronavirus outside of the health-care setting, close household and community contacts of laboratory-confirmed SARS cases were identified and followed up for clinical and laboratory evidence of SARS infection. Individual- and household-level risk factors for transmission were investigated. Nine persons with serological evidence of SARS infection were identified amongst 212 close contacts of 45 laboratory- confirmed SARS cases (secondary attack rate 4·2%, 95% CI 1·5–7). In this cohort, the average number of secondary infections caused by a single infectious case was 0·2. Two community contacts with laboratory evidence of SARS coronavirus infection had mild or sub-clinical infection, representing 3% (2/65) of Vietnamese SARS cases. There was no evidence of transmission of infection before symptom onset. Physically caring for a symptomatic laboratory-confirmed SARS case was the only independent risk factor for SARS transmission (OR 5·78, 95% CI 1·23–24·24).

Url:

DOI: 10.1017/S0950268806006996

Affiliations:

Le document en format XML

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<front><div type="abstract">To evaluate the risk of transmission of SARS coronavirus outside of the health-care setting, close household and community contacts of laboratory-confirmed SARS cases were identified and followed up for clinical and laboratory evidence of SARS infection. Individual- and household-level risk factors for transmission were investigated. Nine persons with serological evidence of SARS infection were identified amongst 212 close contacts of 45 laboratory- confirmed SARS cases (secondary attack rate 4·2%, 95% CI 1·5–7). In this cohort, the average number of secondary infections caused by a single infectious case was 0·2. Two community contacts with laboratory evidence of SARS coronavirus infection had mild or sub-clinical infection, representing 3% (2/65) of Vietnamese SARS cases. There was no evidence of transmission of infection before symptom onset. Physically caring for a symptomatic laboratory-confirmed SARS case was the only independent risk factor for SARS transmission (OR 5·78, 95% CI 1·23–24·24).</div>
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SARS transmission in Vietnam outside of the health-care setting

SARS transmission in Vietnam outside of the health-care setting

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Abstract

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