SrasV1, Ncbi, Curation, bibRecord, 001589

SARS transmission in Vietnam outside of the health-care setting

Identifieur interne : 001589 ( Ncbi/Curation ); précédent : 001588; suivant : 001590

SARS transmission in Vietnam outside of the health-care setting

Auteurs : P. A. Tuan [Viêt Nam] ; P. Horby [Viêt Nam] ; P. N. Dinh [Viêt Nam] ; L. T. Q. Mai [Viêt Nam] ; M. Zambon [Royaume-Uni] ; J. Shah [États-Unis] ; V. Q. Huy [Viêt Nam] ; S. Bloom [États-Unis] ; R. Gopal [Royaume-Uni] ; J. Comer [États-Unis] ; A. Plant [Australie]

Source :

Epidemiology and Infection [ 0950-2688 ] ; 2006.

RBID : PMC:2870589

Abstract

SUMMARY

To evaluate the risk of transmission of SARS coronavirus outside of the health-care setting, close household and community contacts of laboratory-confirmed SARS cases were identified and followed up for clinical and laboratory evidence of SARS infection. Individual- and household-level risk factors for transmission were investigated. Nine persons with serological evidence of SARS infection were identified amongst 212 close contacts of 45 laboratory- confirmed SARS cases (secondary attack rate 4·2%, 95% CI 1·5–7). In this cohort, the average number of secondary infections caused by a single infectious case was 0·2. Two community contacts with laboratory evidence of SARS coronavirus infection had mild or sub-clinical infection, representing 3% (2/65) of Vietnamese SARS cases. There was no evidence of transmission of infection before symptom onset. Physically caring for a symptomatic laboratory-confirmed SARS case was the only independent risk factor for SARS transmission (OR 5·78, 95% CI 1·23–24·24).

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870589

DOI: 10.1017/S0950268806006996
PubMed: 16870029
PubMed Central: 2870589

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PMC:2870589

Le document en format XML

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<author><name sortKey="Tuan, P A" sort="Tuan, P A" uniqKey="Tuan P" first="P. A." last="Tuan">P. A. Tuan</name>
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<author><name sortKey="Horby, P" sort="Horby, P" uniqKey="Horby P" first="P." last="Horby">P. Horby</name>
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<author><name sortKey="Gopal, R" sort="Gopal, R" uniqKey="Gopal R" first="R." last="Gopal">R. Gopal</name>
<affiliation wicri:level="3"><nlm:aff id="aff003">Health Protection Agency, London, UK</nlm:aff>
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<front><div type="abstract" xml:lang="en"><title>SUMMARY</title>
<p>To evaluate the risk of transmission of SARS coronavirus outside of the health-care setting, close household and community contacts of laboratory-confirmed SARS cases were identified and followed up for clinical and laboratory evidence of SARS infection. Individual- and household-level risk factors for transmission were investigated. Nine persons with serological evidence of SARS infection were identified amongst 212 close contacts of 45 laboratory- confirmed SARS cases (secondary attack rate 4·2%, 95% CI 1·5–7). In this cohort, the average number of secondary infections caused by a single infectious case was 0·2. Two community contacts with laboratory evidence of SARS coronavirus infection had mild or sub-clinical infection, representing 3% (2/65) of Vietnamese SARS cases. There was no evidence of transmission of infection before symptom onset. Physically caring for a symptomatic laboratory-confirmed SARS case was the only independent risk factor for SARS transmission (OR 5·78, 95% CI 1·23–24·24).</p>
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SARS transmission in Vietnam outside of the health-care setting

SARS transmission in Vietnam outside of the health-care setting

Source :

Abstract

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