Coronavirus infection and hospitalizations for acute respiratory illness in young children
Identifieur interne : 002E33 ( Main/Exploration ); précédent : 002E32; suivant : 002E34Coronavirus infection and hospitalizations for acute respiratory illness in young children
Auteurs : H. Keipp B. Talbot [États-Unis] ; James E. Crowe Jr. [États-Unis] ; Kathryn M. Edwards [États-Unis] ; Marie R. Griffin [États-Unis] ; Yuwei Zhu [États-Unis] ; Geoffrey A. Weinberg [États-Unis] ; Peter G. Szilagyi [États-Unis] ; Caroline B. Hall [États-Unis] ; Amy B. Podsiad [États-Unis] ; Marika Iwane [Géorgie (pays)] ; John V. Williams [États-Unis]Source :
- Journal of Medical Virology [ 0146-6615 ] ; 2009-05.
English descriptors
- Teeft :
- Care unit, Clinical features, Common colds, Cooperative agreement, Coronavirus, Coronavirus infection, Coronavirus infections, Coronaviruses, Discharge diagnoses, Disease control, Grant number, Grant numbers, Grant sponsor, Hcov, Hcov strains, Healthy children, Hong kong, Hospital admission, Hospitalization, Human coronavirus, Human coronavirus infections, Human coronaviruses, Human metapneumovirus, Infection, Iwane, Kawasaki syndrome, Novel coronavirus, Prospective study, Respiratory syncytial virus, Respiratory tract infections, Vaccine surveillance network, Vanderbilt university, Virol, Young children.
Abstract
There is only limited knowledge on the burden of disease due to both new (HCoV‐NL63 and HKU‐1) and previously discovered coronaviruses (OC43 and 229E) in children. Respiratory specimens and clinical data were prospectively collected in an active, population‐based surveillance study over a 2‐year period from children aged <5 years hospitalized with acute respiratory symptoms or fever. These samples were retrospectively tested by real‐time RT‐PCR for HCoV‐NL63, HKU1, OC43, and 229E. Human coronaviruses (HCoVs) were identified in 2.2% of study children <2 years of age. Rates of HCoV‐associated hospitalization per 10,000 were 10.2 (95% CI 4.3, 17.6), 4.2 (95% CI 1.9, 6.9), and 0 (95% CI 0, 3.7) in children aged <6 months, 6–23 months, and 24–59 months, respectively. Coronaviruses were identified in a modest number of hospitalized children. J. Med. Virol. 81:853–856, 2009. © 2009 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/jmv.21443
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">There is only limited knowledge on the burden of disease due to both new (HCoV‐NL63 and HKU‐1) and previously discovered coronaviruses (OC43 and 229E) in children. Respiratory specimens and clinical data were prospectively collected in an active, population‐based surveillance study over a 2‐year period from children aged <5 years hospitalized with acute respiratory symptoms or fever. These samples were retrospectively tested by real‐time RT‐PCR for HCoV‐NL63, HKU1, OC43, and 229E. Human coronaviruses (HCoVs) were identified in 2.2% of study children <2 years of age. Rates of HCoV‐associated hospitalization per 10,000 were 10.2 (95% CI 4.3, 17.6), 4.2 (95% CI 1.9, 6.9), and 0 (95% CI 0, 3.7) in children aged <6 months, 6–23 months, and 24–59 months, respectively. Coronaviruses were identified in a modest number of hospitalized children. J. Med. Virol. 81:853–856, 2009. © 2009 Wiley‐Liss, Inc.</div>
</front>
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<name sortKey="Crowe Jr, James E" sort="Crowe Jr, James E" uniqKey="Crowe Jr J" first="James E." last="Crowe Jr.">James E. Crowe Jr.</name>
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