Does elevated testosterone result in increased exposure and transmission of parasites?
Identifieur interne : 002E22 ( Main/Exploration ); précédent : 002E21; suivant : 002E23Does elevated testosterone result in increased exposure and transmission of parasites?
Auteurs : Daniel A. Grear [États-Unis] ; Sarah E. Perkins [États-Unis] ; Peter J. Hudson [États-Unis]Source :
- Ecology Letters [ 1461-023X ] ; 2009-06.
English descriptors
- Teeft :
- Aparicio pascual, Apodemus sylvaticus, Assortativity index, Average degree, Average mass, Behaviour, Biol, Blackwell publishing, Body mass, Chicago press, Coefficient, Confidence interval overlap, Contact distributions, Contact rate, Contact rates, Deer mice, Degree distributions, Development core team, Disease dynamics, Ecol, Ecology, Ecology letters, Effect variables, Evolutionary perspective, Experimental treatment, Exponential distribution, Female body mass, Females males, Glmm, Grid, Increase exposure, Individual degree, Individual differences, Individual heterogeneity, Individual males, Individual network degree, Individual node, Individual treatment, Infection rates, Infection status, Infectious contact, Infectious disease dynamics, Larger territories, Leucopus, Male mice, Natural systems, Network analysis, Network degree, Network graphs, Network models, Network size, Network structure, Network theory, Node, Null model, Parasite, Parasite intensity, Parasite transmission, Perkins, Peromyscus, Peromyscus leucopus, Peromyscus maniculatus, Population treatment, Random degree distribution, Rodent, Rodent societies, Sera testosterone levels, Sexual dimorphism, Significant relationship, Sites males, Small sample size, Social networks, Social structure, Standard error, State college, Testosterone, Testosterone drives contact networks, Testosterone levels, Testosterone propionate, Testosterone treatment, Testosterone treatment males, Time period, Transmission dynamics, Treatment group, Treatment period, Trends ecol, Undirected edges, Untreated, Untreated populations, Untreated sites.
Abstract
Male‐biased infection is a common phenomenon in vertebrate‐parasite systems and male‐biased transmission has been experimentally demonstrated. One mechanism that is hypothesized to create male‐biased transmission is the immuno‐suppressive effect of testosterone because it increases susceptibility to infection. Testosterone also influences host behaviour and, consequently, may increase exposure to parasites. To test how testosterone could increase exposure and transmission, we undertook a longitudinal mark‐recapture study where we experimentally elevated testosterone levels in wild male rodents. Individuals in control populations reduced the average number of contacts over the treatment period, while populations with experimentally elevated testosterone levels maintained the number of contacts between hosts. As a result, the transmission potential was higher in testosterone treated populations compared to controls. Our results indicated that males with high‐testosterone levels alter the population‐level contacts, producing different social networks and increasing transmission potential compared to those where testosterone is at background levels.
Url:
DOI: 10.1111/j.1461-0248.2009.01306.x
Affiliations:
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One mechanism that is hypothesized to create male‐biased transmission is the immuno‐suppressive effect of testosterone because it increases susceptibility to infection. Testosterone also influences host behaviour and, consequently, may increase exposure to parasites. To test how testosterone could increase exposure and transmission, we undertook a longitudinal mark‐recapture study where we experimentally elevated testosterone levels in wild male rodents. Individuals in control populations reduced the average number of contacts over the treatment period, while populations with experimentally elevated testosterone levels maintained the number of contacts between hosts. As a result, the transmission potential was higher in testosterone treated populations compared to controls. Our results indicated that males with high‐testosterone levels alter the population‐level contacts, producing different social networks and increasing transmission potential compared to those where testosterone is at background levels.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li></region><settlement><li>University Park (Pennsylvanie)</li></settlement><orgName><li>Université d'État de Pennsylvanie</li></orgName></list><tree><country name="États-Unis"><noRegion><name sortKey="Grear, Daniel A" sort="Grear, Daniel A" uniqKey="Grear D" first="Daniel A." last="Grear">Daniel A. Grear</name></noRegion><name sortKey="Hudson, Peter J" sort="Hudson, Peter J" uniqKey="Hudson P" first="Peter J." last="Hudson">Peter J. Hudson</name><name sortKey="Perkins, Sarah E" sort="Perkins, Sarah E" uniqKey="Perkins S" first="Sarah E." last="Perkins">Sarah E. Perkins</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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