Human coronavirus NL63: a clinically important virus?
Identifieur interne : 002108 ( Main/Exploration ); précédent : 002107; suivant : 002109Human coronavirus NL63: a clinically important virus?
Auteurs : Burtram C. FieldingSource :
- Future Microbiology [ 1746-0913 ] ; 2011.
Descripteurs français
- KwdFr :
- Coronavirus humain NL63 (isolement et purification), Enfant d'âge préscolaire, Humains, Infections de l'appareil respiratoire (anatomopathologie), Infections de l'appareil respiratoire (virologie), Infections de l'appareil respiratoire (épidémiologie), Infections à coronavirus (anatomopathologie), Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Nourrisson, Prévalence, Saisons.
- MESH :
- anatomopathologie : Infections de l'appareil respiratoire, Infections à coronavirus.
- isolement et purification : Coronavirus humain NL63.
- virologie : Infections de l'appareil respiratoire, Infections à coronavirus.
- épidémiologie : Infections de l'appareil respiratoire, Infections à coronavirus.
- Enfant d'âge préscolaire, Humains, Nourrisson, Prévalence, Saisons.
English descriptors
- KwdEn :
- Child, Preschool, Coronavirus Infections (epidemiology), Coronavirus Infections (pathology), Coronavirus Infections (virology), Coronavirus NL63, Human (isolation & purification), Humans, Infant, Prevalence, Respiratory Tract Infections (epidemiology), Respiratory Tract Infections (pathology), Respiratory Tract Infections (virology), Seasons.
- MESH :
- epidemiology : Coronavirus Infections, Respiratory Tract Infections.
- isolation & purification : Coronavirus NL63, Human.
- pathology : Coronavirus Infections, Respiratory Tract Infections.
- virology : Coronavirus Infections, Respiratory Tract Infections.
- Child, Preschool, Humans, Infant, Prevalence, Seasons.
Abstract
Respiratory tract infection is a leading cause of morbidity and mortality worldwide, especially among young children. Human coronaviruses (HCoVs) have only recently been shown to cause both lower and upper respiratory tract infections. To date, five coronaviruses (HCoV-229E, HCoV-OC43, SARS-CoV, HCoV-NL63 and HCoV HKU-1) that infect humans have been identified, four of which (HCoV-229E, HCoV-OC43, HCoV-NL63 and HCoV-HKU-1) circulate continuously in the human population. Human coronavirus NL63 (HCoV-NL63) was first isolated from the aspirate from a 7-month-old baby in early 2004. Infection with HCoV-NL63 has since been shown to be a common worldwide occurrence and has been associated with many clinical symptoms and diagnoses, including severe lower respiratory tract infection, croup and bronchiolitis. HCoV-NL63 causes disease in children, the elderly and the immunocompromised, and has been detected in 1.0–9.3% of respiratory tract infections in children. In this article, the current knowledge of human coronavirus HCoV-NL63, with special reference to the clinical features, prevalence and seasonal incidence, and coinfection with other respiratory viruses, will be discussed.
Url:
DOI: 10.2217/fmb.10.166
PubMed: 21366416
PubMed Central: 7079714
Affiliations:
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Le document en format XML
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Fielding</name><affiliation><nlm:aff id="aff1">Molecular Virology Research Laboratory, Medical Microbiology Cluster, Department of Medical Biosciences, Faculty of Natural Sciences, University of the Western Cape, Private Bag X17, Modderdam Road, Bellville, Western Cape, 7535, South Africa. Tel.: +<phone>27 219 593 620</phone>; Fax: +<fax>27 219 593 125</fax>;<email xlink:href="mailto:bfielding@uwc.ac.za">bfielding@uwc.ac.za</email></nlm:aff></affiliation></author></analytic><series><title level="j">Future Microbiology</title><idno type="ISSN">1746-0913</idno><idno type="eISSN">1746-0921</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Child, Preschool</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (pathology)</term><term>Coronavirus Infections (virology)</term><term>Coronavirus NL63, Human (isolation & purification)</term><term>Humans</term><term>Infant</term><term>Prevalence</term><term>Respiratory Tract Infections (epidemiology)</term><term>Respiratory Tract Infections (pathology)</term><term>Respiratory Tract Infections (virology)</term><term>Seasons</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Coronavirus humain NL63 (isolement et purification)</term><term>Enfant d'âge préscolaire</term><term>Humains</term><term>Infections de l'appareil respiratoire (anatomopathologie)</term><term>Infections de l'appareil respiratoire (virologie)</term><term>Infections de l'appareil respiratoire (épidémiologie)</term><term>Infections à coronavirus (anatomopathologie)</term><term>Infections à coronavirus (virologie)</term><term>Infections à coronavirus (épidémiologie)</term><term>Nourrisson</term><term>Prévalence</term><term>Saisons</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Infections de l'appareil respiratoire</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Coronavirus NL63, Human</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus humain NL63</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Coronavirus Infections</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections de l'appareil respiratoire</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections de l'appareil respiratoire</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Child, Preschool</term><term>Humans</term><term>Infant</term><term>Prevalence</term><term>Seasons</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Enfant d'âge préscolaire</term><term>Humains</term><term>Nourrisson</term><term>Prévalence</term><term>Saisons</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Respiratory tract infection is a leading cause of morbidity and mortality worldwide, especially among young children. Human coronaviruses (HCoVs) have only recently been shown to cause both lower and upper respiratory tract infections. To date, five coronaviruses (HCoV-229E, HCoV-OC43, SARS-CoV, HCoV-NL63 and HCoV HKU-1) that infect humans have been identified, four of which (HCoV-229E, HCoV-OC43, HCoV-NL63 and HCoV-HKU-1) circulate continuously in the human population. Human coronavirus NL63 (HCoV-NL63) was first isolated from the aspirate from a 7-month-old baby in early 2004. Infection with HCoV-NL63 has since been shown to be a common worldwide occurrence and has been associated with many clinical symptoms and diagnoses, including severe lower respiratory tract infection, croup and bronchiolitis. HCoV-NL63 causes disease in children, the elderly and the immunocompromised, and has been detected in 1.0–9.3% of respiratory tract infections in children. In this article, the current knowledge of human coronavirus HCoV-NL63, with special reference to the clinical features, prevalence and seasonal incidence, and coinfection with other respiratory viruses, will be discussed.</p></div></front><back><div1 type="bibliography"><listBibl></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Fielding, Burtram C" sort="Fielding, Burtram C" uniqKey="Fielding B" first="Burtram C" last="Fielding">Burtram C. Fielding</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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