Human coronavirus NL63: a clinically important virus?
Identifieur interne : 000B43 ( Pmc/Checkpoint ); précédent : 000B42; suivant : 000B44Human coronavirus NL63: a clinically important virus?
Auteurs : Burtram C. FieldingSource :
- Future Microbiology [ 1746-0913 ] ; 2011.
Abstract
Respiratory tract infection is a leading cause of morbidity and mortality worldwide, especially among young children. Human coronaviruses (HCoVs) have only recently been shown to cause both lower and upper respiratory tract infections. To date, five coronaviruses (HCoV-229E, HCoV-OC43, SARS-CoV, HCoV-NL63 and HCoV HKU-1) that infect humans have been identified, four of which (HCoV-229E, HCoV-OC43, HCoV-NL63 and HCoV-HKU-1) circulate continuously in the human population. Human coronavirus NL63 (HCoV-NL63) was first isolated from the aspirate from a 7-month-old baby in early 2004. Infection with HCoV-NL63 has since been shown to be a common worldwide occurrence and has been associated with many clinical symptoms and diagnoses, including severe lower respiratory tract infection, croup and bronchiolitis. HCoV-NL63 causes disease in children, the elderly and the immunocompromised, and has been detected in 1.0–9.3% of respiratory tract infections in children. In this article, the current knowledge of human coronavirus HCoV-NL63, with special reference to the clinical features, prevalence and seasonal incidence, and coinfection with other respiratory viruses, will be discussed.
Url:
DOI: 10.2217/fmb.10.166
PubMed: 21366416
PubMed Central: 7079714
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:7079714Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Human coronavirus NL63: a clinically important virus?</title><author><name sortKey="Fielding, Burtram C" sort="Fielding, Burtram C" uniqKey="Fielding B" first="Burtram C" last="Fielding">Burtram C. Fielding</name><affiliation><nlm:aff id="aff1">Molecular Virology Research Laboratory, Medical Microbiology Cluster, Department of Medical Biosciences, Faculty of Natural Sciences, University of the Western Cape, Private Bag X17, Modderdam Road, Bellville, Western Cape, 7535, South Africa. Tel.: +<phone>27 219 593 620</phone>; Fax: +<fax>27 219 593 125</fax>;<email xlink:href="mailto:bfielding@uwc.ac.za">bfielding@uwc.ac.za</email></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21366416</idno><idno type="pmc">7079714</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079714</idno><idno type="RBID">PMC:7079714</idno><idno type="doi">10.2217/fmb.10.166</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">001777</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001777</idno><idno type="wicri:Area/Pmc/Curation">001777</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001777</idno><idno type="wicri:Area/Pmc/Checkpoint">000B43</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000B43</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Human coronavirus NL63: a clinically important virus?</title><author><name sortKey="Fielding, Burtram C" sort="Fielding, Burtram C" uniqKey="Fielding B" first="Burtram C" last="Fielding">Burtram C. Fielding</name><affiliation><nlm:aff id="aff1">Molecular Virology Research Laboratory, Medical Microbiology Cluster, Department of Medical Biosciences, Faculty of Natural Sciences, University of the Western Cape, Private Bag X17, Modderdam Road, Bellville, Western Cape, 7535, South Africa. Tel.: +<phone>27 219 593 620</phone>; Fax: +<fax>27 219 593 125</fax>;<email xlink:href="mailto:bfielding@uwc.ac.za">bfielding@uwc.ac.za</email></nlm:aff></affiliation></author></analytic><series><title level="j">Future Microbiology</title><idno type="ISSN">1746-0913</idno><idno type="eISSN">1746-0921</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Respiratory tract infection is a leading cause of morbidity and mortality worldwide, especially among young children. Human coronaviruses (HCoVs) have only recently been shown to cause both lower and upper respiratory tract infections. To date, five coronaviruses (HCoV-229E, HCoV-OC43, SARS-CoV, HCoV-NL63 and HCoV HKU-1) that infect humans have been identified, four of which (HCoV-229E, HCoV-OC43, HCoV-NL63 and HCoV-HKU-1) circulate continuously in the human population. Human coronavirus NL63 (HCoV-NL63) was first isolated from the aspirate from a 7-month-old baby in early 2004. Infection with HCoV-NL63 has since been shown to be a common worldwide occurrence and has been associated with many clinical symptoms and diagnoses, including severe lower respiratory tract infection, croup and bronchiolitis. HCoV-NL63 causes disease in children, the elderly and the immunocompromised, and has been detected in 1.0–9.3% of respiratory tract infections in children. In this article, the current knowledge of human coronavirus HCoV-NL63, with special reference to the clinical features, prevalence and seasonal incidence, and coinfection with other respiratory viruses, will be discussed.</p></div></front><back><div1 type="bibliography"><listBibl></listBibl></div1></back></TEI><pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Future Microbiol</journal-id><journal-id journal-id-type="iso-abbrev">Future Microbiol</journal-id><journal-id journal-id-type="publisher-id">FMB</journal-id><journal-title-group><journal-title>Future Microbiology</journal-title></journal-title-group><issn pub-type="ppub">1746-0913</issn><issn pub-type="epub">1746-0921</issn><publisher><publisher-name>Future Medicine Ltd</publisher-name><publisher-loc>London, UK</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">21366416</article-id><article-id pub-id-type="pmc">7079714</article-id><article-id pub-id-type="doi">10.2217/fmb.10.166</article-id><article-categories><subj-group subj-group-type="heading"><subject>Special Report</subject></subj-group></article-categories><title-group><article-title>Human coronavirus NL63: a clinically important virus?</article-title><alt-title alt-title-type="running-head">Human coronavirus NL63: a clinically important virus?</alt-title><alt-title alt-title-type="running-head">Fielding</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Fielding</surname><given-names>Burtram C</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><aff id="aff1"><label>1</label>Molecular Virology Research Laboratory, Medical Microbiology Cluster, Department of Medical Biosciences, Faculty of Natural Sciences, University of the Western Cape, Private Bag X17, Modderdam Road, Bellville, Western Cape, 7535, South Africa. Tel.: +<phone>27 219 593 620</phone>; Fax: +<fax>27 219 593 125</fax>;<email xlink:href="mailto:bfielding@uwc.ac.za">bfielding@uwc.ac.za</email></aff></contrib-group><pub-date pub-type="ppub"><month>2</month><year>2011</year></pub-date><pub-date pub-type="epub"><day>2</day><month>3</month><year>2011</year></pub-date><pub-date pub-type="pmc-release"><day>2</day><month>3</month><year>2011</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on the
<volume>6</volume><issue>2</issue><fpage>153</fpage><lpage>159</lpage><permissions><copyright-statement>© 2011 Future Medicine Ltd</copyright-statement><copyright-year>2011</copyright-year><license license-type="open-access"><license-p>This work is licensed under the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 License</ext-link></license-p></license></permissions><self-uri content-type="pdf" xlink:type="simple" xlink:href="fmb-06-153.pdf"></self-uri><abstract><p>Respiratory tract infection is a leading cause of morbidity and mortality worldwide, especially among young children. Human coronaviruses (HCoVs) have only recently been shown to cause both lower and upper respiratory tract infections. To date, five coronaviruses (HCoV-229E, HCoV-OC43, SARS-CoV, HCoV-NL63 and HCoV HKU-1) that infect humans have been identified, four of which (HCoV-229E, HCoV-OC43, HCoV-NL63 and HCoV-HKU-1) circulate continuously in the human population. Human coronavirus NL63 (HCoV-NL63) was first isolated from the aspirate from a 7-month-old baby in early 2004. Infection with HCoV-NL63 has since been shown to be a common worldwide occurrence and has been associated with many clinical symptoms and diagnoses, including severe lower respiratory tract infection, croup and bronchiolitis. HCoV-NL63 causes disease in children, the elderly and the immunocompromised, and has been detected in 1.0–9.3% of respiratory tract infections in children. In this article, the current knowledge of human coronavirus HCoV-NL63, with special reference to the clinical features, prevalence and seasonal incidence, and coinfection with other respiratory viruses, will be discussed.</p></abstract><kwd-group kwd-group-type="author"><title>Keywords</title><kwd>childhood viral infections</kwd><kwd>clinical features</kwd><kwd>HCoV-NL63</kwd><kwd>human coronavirus</kwd><kwd>lower respiratory tract infection</kwd><kwd>respiratory viruses</kwd><kwd>upper respiratory tract infection</kwd></kwd-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Fielding, Burtram C" sort="Fielding, Burtram C" uniqKey="Fielding B" first="Burtram C" last="Fielding">Burtram C. Fielding</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000B43 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 000B43 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Pmc
|étape= Checkpoint
|type= RBID
|clé= PMC:7079714
|texte= Human coronavirus NL63: a clinically important virus?
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:21366416" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |