plethy: management of whole body plethysmography data in R.
Identifieur interne : 001198 ( Main/Exploration ); précédent : 001197; suivant : 001199plethy: management of whole body plethysmography data in R.
Auteurs : Daniel Bottomly [États-Unis] ; Beth Wilmot [États-Unis] ; Shannon K. Mcweeney [États-Unis]Source :
- BMC bioinformatics [ 1471-2105 ] ; 2015.
Descripteurs français
- KwdFr :
- Animaux, Coronavirus (génétique), Grippe chez les oiseaux (virologie), Génome viral, Génomique, Infections à Orthomyxoviridae (virologie), Infographie, Logiciel, Modèles statistiques, Oiseaux, Phénotype, Pléthysmographie du corps entier, Respiration (génétique), Souris, Souris de lignée C57BL, Syndrome respiratoire aigu sévère (virologie), Virus de la grippe A (génétique).
- MESH :
- génétique : Coronavirus, Respiration, Virus de la grippe A.
- virologie : Grippe chez les oiseaux, Infections à Orthomyxoviridae, Syndrome respiratoire aigu sévère.
- Animaux, Génome viral, Génomique, Infographie, Logiciel, Modèles statistiques, Oiseaux, Phénotype, Pléthysmographie du corps entier, Souris, Souris de lignée C57BL.
English descriptors
- KwdEn :
- Animals, Birds, Computer Graphics, Coronavirus (genetics), Genome, Viral, Genomics, Influenza A virus (genetics), Influenza in Birds (virology), Mice, Mice, Inbred C57BL, Models, Statistical, Orthomyxoviridae Infections (virology), Phenotype, Plethysmography, Whole Body, Respiration (genetics), Severe Acute Respiratory Syndrome (virology), Software.
- MESH :
- genetics : Coronavirus, Influenza A virus, Respiration.
- virology : Influenza in Birds, Orthomyxoviridae Infections, Severe Acute Respiratory Syndrome.
- Animals, Birds, Computer Graphics, Genome, Viral, Genomics, Mice, Mice, Inbred C57BL, Models, Statistical, Phenotype, Plethysmography, Whole Body, Software.
Abstract
Characterization of respiratory phenotypes can enhance complex trait and genomic studies involving allergic/autoimmune and infectious diseases. Many aspects of respiration can be measured using devices known as plethysmographs that can measure thoracic movement. One such approach (the Buxco platform) performs unrestrained whole body plethysmography on mice which infers thoracic movements from pressure differences from the act of inhalation and exhalation. While proprietary software is available to perform basic statistical analysis as part of machine's bundled software, it is desirable to be able to incorporate these analyses into high-throughput pipelines and integrate them with other data types, as well as leverage the wealth of analytic and visualization approaches provided by the R statistical computing environment.
DOI: 10.1186/s12859-015-0547-7
PubMed: 25924931
Affiliations:
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Le document en format XML
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<term>Computer Graphics</term>
<term>Coronavirus (genetics)</term>
<term>Genome, Viral</term>
<term>Genomics</term>
<term>Influenza A virus (genetics)</term>
<term>Influenza in Birds (virology)</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>Models, Statistical</term>
<term>Orthomyxoviridae Infections (virology)</term>
<term>Phenotype</term>
<term>Plethysmography, Whole Body</term>
<term>Respiration (genetics)</term>
<term>Severe Acute Respiratory Syndrome (virology)</term>
<term>Software</term>
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<term>Coronavirus (génétique)</term>
<term>Grippe chez les oiseaux (virologie)</term>
<term>Génome viral</term>
<term>Génomique</term>
<term>Infections à Orthomyxoviridae (virologie)</term>
<term>Infographie</term>
<term>Logiciel</term>
<term>Modèles statistiques</term>
<term>Oiseaux</term>
<term>Phénotype</term>
<term>Pléthysmographie du corps entier</term>
<term>Respiration (génétique)</term>
<term>Souris</term>
<term>Souris de lignée C57BL</term>
<term>Syndrome respiratoire aigu sévère (virologie)</term>
<term>Virus de la grippe A (génétique)</term>
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<term>Influenza A virus</term>
<term>Respiration</term>
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<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus</term>
<term>Respiration</term>
<term>Virus de la grippe A</term>
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<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe chez les oiseaux</term>
<term>Infections à Orthomyxoviridae</term>
<term>Syndrome respiratoire aigu sévère</term>
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<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza in Birds</term>
<term>Orthomyxoviridae Infections</term>
<term>Severe Acute Respiratory Syndrome</term>
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<term>Birds</term>
<term>Computer Graphics</term>
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<term>Genomics</term>
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<term>Modèles statistiques</term>
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<front><div type="abstract" xml:lang="en">Characterization of respiratory phenotypes can enhance complex trait and genomic studies involving allergic/autoimmune and infectious diseases. Many aspects of respiration can be measured using devices known as plethysmographs that can measure thoracic movement. One such approach (the Buxco platform) performs unrestrained whole body plethysmography on mice which infers thoracic movements from pressure differences from the act of inhalation and exhalation. While proprietary software is available to perform basic statistical analysis as part of machine's bundled software, it is desirable to be able to incorporate these analyses into high-throughput pipelines and integrate them with other data types, as well as leverage the wealth of analytic and visualization approaches provided by the R statistical computing environment.</div>
</front>
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<name sortKey="Wilmot, Beth" sort="Wilmot, Beth" uniqKey="Wilmot B" first="Beth" last="Wilmot">Beth Wilmot</name>
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