plethy: management of whole body plethysmography data in R.
Identifieur interne : 002A67 ( Ncbi/Curation ); précédent : 002A66; suivant : 002A68plethy: management of whole body plethysmography data in R.
Auteurs : Daniel Bottomly [États-Unis] ; Beth Wilmot [États-Unis] ; Shannon K. Mcweeney [États-Unis]Source :
- BMC bioinformatics [ 1471-2105 ] ; 2015.
Descripteurs français
- KwdFr :
- Animaux, Coronavirus (génétique), Grippe chez les oiseaux (virologie), Génome viral, Génomique, Infections à Orthomyxoviridae (virologie), Infographie, Logiciel, Modèles statistiques, Oiseaux, Phénotype, Pléthysmographie du corps entier, Respiration (génétique), Souris, Souris de lignée C57BL, Syndrome respiratoire aigu sévère (virologie), Virus de la grippe A (génétique).
- MESH :
- génétique : Coronavirus, Respiration, Virus de la grippe A.
- virologie : Grippe chez les oiseaux, Infections à Orthomyxoviridae, Syndrome respiratoire aigu sévère.
- Animaux, Génome viral, Génomique, Infographie, Logiciel, Modèles statistiques, Oiseaux, Phénotype, Pléthysmographie du corps entier, Souris, Souris de lignée C57BL.
English descriptors
- KwdEn :
- Animals, Birds, Computer Graphics, Coronavirus (genetics), Genome, Viral, Genomics, Influenza A virus (genetics), Influenza in Birds (virology), Mice, Mice, Inbred C57BL, Models, Statistical, Orthomyxoviridae Infections (virology), Phenotype, Plethysmography, Whole Body, Respiration (genetics), Severe Acute Respiratory Syndrome (virology), Software.
- MESH :
- genetics : Coronavirus, Influenza A virus, Respiration.
- virology : Influenza in Birds, Orthomyxoviridae Infections, Severe Acute Respiratory Syndrome.
- Animals, Birds, Computer Graphics, Genome, Viral, Genomics, Mice, Mice, Inbred C57BL, Models, Statistical, Phenotype, Plethysmography, Whole Body, Software.
Abstract
Characterization of respiratory phenotypes can enhance complex trait and genomic studies involving allergic/autoimmune and infectious diseases. Many aspects of respiration can be measured using devices known as plethysmographs that can measure thoracic movement. One such approach (the Buxco platform) performs unrestrained whole body plethysmography on mice which infers thoracic movements from pressure differences from the act of inhalation and exhalation. While proprietary software is available to perform basic statistical analysis as part of machine's bundled software, it is desirable to be able to incorporate these analyses into high-throughput pipelines and integrate them with other data types, as well as leverage the wealth of analytic and visualization approaches provided by the R statistical computing environment.
DOI: 10.1186/s12859-015-0547-7
PubMed: 25924931
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pubmed:25924931Le document en format XML
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Mcweeney</name><affiliation wicri:level="2"><nlm:affiliation>Oregon Clinical and Translational Research Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd97239, Portland, Oregon, US. mcweeney@ohsu.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Oregon Clinical and Translational Research Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd97239, Portland, Oregon</wicri:regionArea><placeName><region type="state">Oregon</region></placeName></affiliation></author></analytic><series><title level="j">BMC bioinformatics</title><idno type="eISSN">1471-2105</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Birds</term><term>Computer Graphics</term><term>Coronavirus (genetics)</term><term>Genome, Viral</term><term>Genomics</term><term>Influenza A virus (genetics)</term><term>Influenza in Birds (virology)</term><term>Mice</term><term>Mice, Inbred C57BL</term><term>Models, Statistical</term><term>Orthomyxoviridae Infections (virology)</term><term>Phenotype</term><term>Plethysmography, Whole Body</term><term>Respiration (genetics)</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Software</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Coronavirus (génétique)</term><term>Grippe chez les oiseaux (virologie)</term><term>Génome viral</term><term>Génomique</term><term>Infections à Orthomyxoviridae (virologie)</term><term>Infographie</term><term>Logiciel</term><term>Modèles statistiques</term><term>Oiseaux</term><term>Phénotype</term><term>Pléthysmographie du corps entier</term><term>Respiration (génétique)</term><term>Souris</term><term>Souris de lignée C57BL</term><term>Syndrome respiratoire aigu sévère (virologie)</term><term>Virus de la grippe A (génétique)</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus</term><term>Influenza A virus</term><term>Respiration</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus</term><term>Respiration</term><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe chez les oiseaux</term><term>Infections à Orthomyxoviridae</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza in Birds</term><term>Orthomyxoviridae Infections</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Birds</term><term>Computer Graphics</term><term>Genome, Viral</term><term>Genomics</term><term>Mice</term><term>Mice, Inbred C57BL</term><term>Models, Statistical</term><term>Phenotype</term><term>Plethysmography, Whole Body</term><term>Software</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Génome viral</term><term>Génomique</term><term>Infographie</term><term>Logiciel</term><term>Modèles statistiques</term><term>Oiseaux</term><term>Phénotype</term><term>Pléthysmographie du corps entier</term><term>Souris</term><term>Souris de lignée C57BL</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Characterization of respiratory phenotypes can enhance complex trait and genomic studies involving allergic/autoimmune and infectious diseases. Many aspects of respiration can be measured using devices known as plethysmographs that can measure thoracic movement. One such approach (the Buxco platform) performs unrestrained whole body plethysmography on mice which infers thoracic movements from pressure differences from the act of inhalation and exhalation. While proprietary software is available to perform basic statistical analysis as part of machine's bundled software, it is desirable to be able to incorporate these analyses into high-throughput pipelines and integrate them with other data types, as well as leverage the wealth of analytic and visualization approaches provided by the R statistical computing environment.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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