Inactivation of three emerging viruses - severe acute respiratory syndrome coronavirus, Crimean-Congo haemorrhagic fever virus and Nipah virus - in platelet concentrates by ultraviolet C light and in plasma by methylene blue plus visible light.
Identifieur interne : 000555 ( Main/Exploration ); précédent : 000554; suivant : 000556Inactivation of three emerging viruses - severe acute respiratory syndrome coronavirus, Crimean-Congo haemorrhagic fever virus and Nipah virus - in platelet concentrates by ultraviolet C light and in plasma by methylene blue plus visible light.
Auteurs : Markus Eickmann [Allemagne] ; Ute Gravemann [Allemagne] ; Wiebke Handke [Allemagne] ; Frank Tolksdorf [Allemagne] ; Stefan Reichenberg [Allemagne] ; Thomas H. Müller [Allemagne] ; Axel Seltsam [Allemagne]Source :
- Vox sanguinis [ 1423-0410 ] ; 2020.
Abstract
Emerging viruses like severe acute respiratory syndrome coronavirus (SARS-CoV), Crimean-Congo haemorrhagic fever virus (CCHFV) and Nipah virus (NiV) have been identified to pose a potential threat to transfusion safety. In this study, the ability of the THERAFLEX UV-Platelets and THERAFLEX MB-Plasma pathogen inactivation systems to inactivate these viruses in platelet concentrates and plasma, respectively, was investigated.
DOI: 10.1111/vox.12888
PubMed: 31930543
Affiliations:
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<front><div type="abstract" xml:lang="en">Emerging viruses like severe acute respiratory syndrome coronavirus (SARS-CoV), Crimean-Congo haemorrhagic fever virus (CCHFV) and Nipah virus (NiV) have been identified to pose a potential threat to transfusion safety. In this study, the ability of the THERAFLEX UV-Platelets and THERAFLEX MB-Plasma pathogen inactivation systems to inactivate these viruses in platelet concentrates and plasma, respectively, was investigated.</div>
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